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Difficulties encountered by physicians and mental health professionals in evaluating and caring for affective and behavioral problems in pediatric brain tumor survivors.

Support Care Cancer 2021 May 14. Epub 2021 May 14.

Psycho-Oncology Unit, Gustave Roussy, 114, Rue Edouard Vaillant, 94805, Villejuif Cedex, France.

Background: Pediatric brain tumor survivors (PBTS) present a high risk for emotional and behavioral disorders. When addressing these difficulties, differences in study designs; variety of and disagreement about diagnoses; and intricate links of emotional, behavioral, and cognitive issues may complicate the interpretation of studies and probably also the work of clinicians. We aimed to survey the difficulties perceived by physicians and mental health professionals in their practice and their interest in developing a new evaluative tool. Read More

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Assistance from Automated ASPECTS Software Improves Reader Performance.

J Stroke Cerebrovasc Dis 2021 May 10;30(7):105829. Epub 2021 May 10.

Department of Radiology, Neuroimaging and Neurointervention Division, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, United States.

Purpose: To compare physicians' ability to read Alberta Stroke Program Early CT Score (ASPECTS) in patients with a large vessel occlusion within 6 hours of symptom onset when assisted by a machine learning-based automatic software tool, compared with their unassisted score.

Materials And Methods: 50 baseline CT scans selected from two prior studies (CRISP and GAMES-RP) were read by 3 experienced neuroradiologists who were provided access to a follow-up MRI. The average ASPECT score of these reads was used as the reference standard. Read More

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Double Dose Desogestrel: Is it effective in Adolescent Menstrual Dysfunction?

J Pediatr Adolesc Gynecol 2021 May 11. Epub 2021 May 11.

Paediatric and Adolescent Gynaecology Department, Alder Hey Children's Hospital, Liverpool Women's Hospital, Liverpool, UK.

Study Objective: Adolescent menstrual dysfunction (AMD) is a common cause of iron deficiency anaemia and absences from school. The management of AMD with single and double dose desogestrel is largely based on anecdotal evidence. Our aim is to describe the effectiveness and safety of both dosing strategies in our clinic cohort to help guide future management. Read More

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Acute otitis externa: Consensus definition, diagnostic criteria and core outcome set development.

PLoS One 2021 14;16(5):e0251395. Epub 2021 May 14.

Salford Royal Hospital, Salford, United Kingdom.

Objective: Evidence for the management of acute otitis externa (AOE) is limited, with unclear diagnostic criteria and variably reported outcome measures that may not reflect key stakeholder priorities. We aimed to develop 1) a definition, 2) diagnostic criteria and 3) a core outcome set (COS) for AOE.

Study Design: COS development according to Core Outcome Measures in Effectiveness Trials (COMET) methodology and parallel consensus selection of diagnostic criteria/definition. Read More

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Fast prototyping of a local fuzzy search system for decision support and retraining of hospital staff during pandemic.

Health Inf Sci Syst 2021 Dec 11;9(1):21. Epub 2021 May 11.

Pavlov First Saint Petersburg State Medical University, L'va Tolstogo str. 6-8, Saint Petersburg, 197022 Russia.

Purpose: The COVID-19 pandemic showed an urgent need for decision support systems to help doctors at a time of stress and uncertainty. However, significant differences in hospital conditions, as well as skepticism of doctors about machine learning algorithms, limit their introduction into clinical practice. Our goal was to test and apply the principle of "patient-like-mine" decision support in rapidly changing conditions of a pandemic. Read More

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December 2021

A physician assistant entry-level doctoral degree: more harm than good?

BMC Med Educ 2021 May 14;21(1):274. Epub 2021 May 14.

Physician Assistant Leadership and Learning Academy (PALLA), University of Maryland Baltimore Graduate School, 620 West Lexington Street, Baltimore, MD, USA.

Background: As most health professions in the United States have adopted clinical or practice doctorates, there has been an ongoing debate on whether physician assistants (PAs) should transition from a master's to a doctorate as the terminal degree. The authors examined perceived risks, benefits and impact of transitioning to an entry-level PA doctoral degree.

Methods: A multi-prong, mixed-methods approach was used that included a literature review and collecting quantitative and qualitative data using a survey and interviews. Read More

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Effects of high-fidelity simulation education on medical students' anxiety and confidence.

PLoS One 2021 13;16(5):e0251078. Epub 2021 May 13.

Department of Pulmonary and Critical Care Medicine, Ajou University School of Medicine, Suwon, South Korea.

Introduction: Psychological factors such as anxiety and confidence that students have in the patient care situation are important in that this affects the actual clinical performance. Students who are just starting clinical practice have a lack of clinical knowledge, skill proficiency, and patient communication skills, so they experience anxiety and lack of confidence in clinical setting. Practice in a safe environment, such as simulation education, can help students perform more settled and competently in patient care. Read More

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Multi-scale attention-based convolutional neural network for classification of breast masses in mammograms.

Med Phys 2021 May 13. Epub 2021 May 13.

College of Data Science, Taiyuan University of Technology, No.209 university street, Taiyuan, China, 030600.

Purpose: Breast cancer is the cancer with the highest incidence in women, and early detection can effectively improve the survival rate of patients. Mammography is an important method for physicians to screening breast cancer, but the diagnosis of mammograms by physicians depends largely on clinical practice experience. Studies have shown that using computer aided diagnosis techniques can help doctors diagnose breast cancer. Read More

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Development and implementation of a clinician report to reduce unnecessary urine drug screen testing in the ED: a quality improvement initiative.

Emerg Med J 2021 May 12. Epub 2021 May 12.

Emergency Medicine, Saskatchewan Health Authority, Regina, Saskatchewan, Canada.

Background: Unnecessary testing is a problem-facing healthcare systems around the world striving to achieve sustainable care. Despite knowing this problem exists, clinicians continue to order tests that do not contribute to patient care. Using behavioural and implementation science can help address this problem. Read More

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Involvement of mental health professionals in the treatment of tuberous sclerosis complex-associated neuropsychiatric disorders (TAND): results of a multinational European electronic survey.

Orphanet J Rare Dis 2021 May 12;16(1):216. Epub 2021 May 12.

Robert Debré University Hospital, Paris, France.

Background: Tuberous sclerosis complex (TSC) is a rare, genetic, multisystem disorder characterized by the growth of hamartomas in several organs, including the brain, kidneys, heart, eyes, and lungs. Even though over 90% of patients will have some form of TSC-associated neuropsychiatric disorder (TAND), there is an apparent lack of involvement of mental health professionals (MHPs) in the care of patients with TSC. The aim of this study was to determine the current level of TAND awareness in the TSC community and to identify possible barriers to effective multidisciplinary collaboration between MHPs and other healthcare providers (HCPs) in TAND management. Read More

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Utility of Volumetric Metabolic Parameters on Preoperative FDG PET/CT for Predicting Tumor Lymphovascular Invasion in Non-Small Cell Lung Cancer.

AJR Am J Roentgenol 2021 May 12. Epub 2021 May 12.

Department of Nuclear Medicine, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan 430071, Hubei Province, China.

Lymphovascular invasion (LVI) is an adverse prognostic indicator in non-small cell lung cancer (NSCLC) and serves as an indication for postoperative adjuvant chemotherapy recommendation after resection. To assess the utility of clinicopathologic factors and volumetric metabolic parameters from preoperative FDG PET/CT in predicting primary tumor LVI in NSCLC. This retrospective study included 161 patients (mean age, 61. Read More

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Clinical analysis and a novel risk predictive nomogram for 155 adult patients with hemophagocytic lymphohistiocytosis.

Ann Hematol 2021 May 12. Epub 2021 May 12.

Department and Institute of Infectious Disease, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

Recently, more and more attention has been paid on adult hemophagocytic lymphohistiocytosis (HLH), a disease with complicated symptoms and high mortality. In order to analyze the clinical characteristics and prediction risk factors of mortality, we designed a retrospective study with 1-year follow-up and included 155 patients admitted to Tongji Hospital diagnosed as HLH. One hundred seven patients formed the training cohort for nomogram development, and 48 patients formed the validation cohort to confirm the model's performance. Read More

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Thrombosis of the Portal Vein and Superior Mesenteric Vein in a Patient With Subclinical COVID-19 Infection.

Cureus 2021 Apr 8;13(4):e14366. Epub 2021 Apr 8.

Non-Invasive Cardiology, Fortis Escorts Hospital, Amritsar, IND.

More than 122 million cases of COVID-19 infection have been documented, and hundreds of thousands are being added every day. Several co-morbidities are associated with COVID-19, among which hypercoagulability has garnered the attention of many doctors and researchers. Most cases of vascular thrombosis are noted in intensive care unit (ICU) patients with serious disease; among these, many cases of deep venous thrombosis and pulmonary embolism have been noted. Read More

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Neural network analysis of clinical variables predicts escalated care in COVID-19 patients: a retrospective study.

PeerJ 2021 19;9:e11205. Epub 2021 Apr 19.

Department of Radiology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.

This study sought to identify the most important clinical variables that can be used to determine which COVID-19 patients hospitalized in the general floor will need escalated care early on using neural networks (NNs). Analysis was performed on hospitalized COVID-19 patients between 7 February 2020 and 4 May 2020 in Stony Brook Hospital. Demographics, comorbidities, laboratory tests, vital signs and blood gases were collected. Read More

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Uncontrolled Asthma: Unmet Needs in the Management of Patients.

J Asthma Allergy 2021 3;14:457-466. Epub 2021 May 3.

Department of Medicine, University of Verona, Verona, Italy.

The recent scientific research has provided clinicians with the tools for substantially upgrading the standard of care in the field of bronchial asthma. Nevertheless, satisfactory asthma control still remains an unmet need worldwide. Identifying the major determinants of poor control in different asthma severity levels represents the first step towards the improvement of the overall patients' management. Read More

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CT scan chest findings in symptomatic COVID-19 patients: a reliable alternative for diagnosis.

Ghana Med J 2020 Dec;54(4 Suppl):97-99

Department of Radiology, University of Ghana Medical School, Korle Bu, Accra.

Computed Tomography (CT) scan of the chest plays an important role in the diagnosis and management of Coronavirus disease 2019 (COVID-19), the disease caused by the novel coronavirus SARS-CoV-2. COVID-19 pneumonia shows typical CT Scan features which can aid diagnoses and therefore help in the early detection and isolation of infected patients. CT scanners are readily available in many parts of Ghana. Read More

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December 2020