615,064 results match your criteria healthy people


The poorly conducted orchestra of steroid hormones, oxidative stress and inflammation in frailty needs a maestro: Regular physical exercise.

Exp Gerontol 2021 Sep 21:111562. Epub 2021 Sep 21.

Health Sciences Research Unit: Nursing (UICISA: E), Nursing School of Coimbra (ESEnfC), Coimbra, Portugal; Institute Polytechnic of Maia, Porto, Portugal; University of Coimbra, Research Unit for Sport and Physical Activity (CIDAF, UID/PTD/04213/2019) at Faculty of Sport Science and Physical Education, (FCDEF-UC), Portugal. Electronic address:

This review outlines the various factors associated with unhealthy aging which includes becoming frail and dependent. With many people not engaging in recommended exercise, facilitators and barriers to engage with exercise must be investigated to promote exercise uptake and adherence over the lifespan for different demographics, including the old, less affluent, women, and those with different cultural-ethnic backgrounds. Governmental and locally funded public health messages and environmental facilitation (gyms, parks etc. Read More

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September 2021

Electroencephalographic evidence of unconscious and conscious attentional bias in people with functional gastrointestinal disorders: A pilot study.

Int J Psychophysiol 2021 Sep 21. Epub 2021 Sep 21.

Department of Psychology, Macquarie University, Sydney, Australia.

Debate continues as to whether an attentional bias towards threat displayed by sufferers of functional gastrointestinal disorders (FGIDs) is conscious and, thus, more amenable to change through psychological therapy. We compared the amplitudes of early (unconscious) and later (conscious) electroencephalographic (EEG) event-related potentials following silent reading of symptom-related, emotionally neutral, and emotionally negative nouns across two participant groups: 30 female FGID-sufferers who met diagnostic criteria for irritable bowel syndrome or functional dyspepsia, and 30 female healthy controls. Analogous indices based on alpha desynchronization were also examined, as were correlations between the EEG-based indices and a range of psychosocial variables. Read More

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September 2021

Endophenotype and Psychiatry: an Interesting Combination.

Psychiatr Danub 2021 Sep;33(Suppl 9):26-29

Psychiatric Studies Center (Cen.Stu.Psi.), Piazza Portici, 11 - 25050 Provaglio d'Iseo (BS), Italy ,

The endophenotype is a measurable component which is characterized as an intermediate part of the path existing between the genotype and phenotype of a disease. In the context of psychiatric pathologies, an endophenotype is such if it shares inheritable variations with it, if it is evident both during the active and inactive phases of the pathology, if it is co-transmitted in the family, and if it is evident in both affected family members from pathology, and in healthy people. This review reports the available literature data of the interesting combination between endophenotype and psychiatry. Read More

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September 2021

Developing State Health Improvement Plans: Exploring States' Use of Healthy People.

J Public Health Manag Pract 2021 Nov-Dec 01;27(Suppl 6):S274-S279

NORC at the University of Chicago, Bethesda, MD.

Background: While Healthy People outlines a national framework for improving the health of the nation, many states develop State Health Improvement Plans (SHIPs) to set priorities to improve the health of their residents. The purpose of this study was to understand the processes that states use to develop their SHIPs, how states align their SHIPs with Healthy People, and challenges that states face using Healthy People.

Methods: NORC conducted semistructured interviews with 9 state health department representatives who were responsible for SHIPs. Read More

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September 2021

Healthy People 2030 Leading Health Indicators and Overall Health and Well-being Measures: Opportunities to Assess and Improve the Health and Well-being of the Nation.

J Public Health Manag Pract 2021 Nov-Dec 01;27(Suppl 6):S235-S241

Office of Disease Prevention and Health Promotion, Office of the Assistant Secretary for Health, Office of the Secretary, US Department of Health and Human Services, Washington, District of Columbia (Ms Ochiai, Ms Kigenyi, and Ms Blakey); Secretary's Advisory Committee on National Health Promotion and Disease Prevention Objectives for 2030 (former) (Dr Sondik, Dr Pronk, and Dr Kleinman); NORC at the University of Chicago, Bethesda, Maryland (Ms Fromknecht and Ms Heffernan); and Health ConTexts, LLC, Silver Spring, Maryland (Ms Brewer).

Context: Released by the US Department of Health and Human Services (HHS) every decade since 1980, Healthy People identifies science-based objectives with targets to monitor progress and motivate and focus action. Healthy People 2030 is the current iteration of the Healthy People initiative.

Program: Healthy People 2030 includes 3 sets of measures-Healthy People 2030 objectives, Leading Health Indicators (LHIs), and Overall Health and Well-being Measures (OHMs). Read More

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September 2021

Healthy People 2030: A Beacon for Addressing Health Disparities and Health Equity.

Authors:
Rachel L Levine

J Public Health Manag Pract 2021 Nov-Dec 01;27(Suppl 6):S220-S221

Office of the Assistant Secretary for Health, Office of the Secretary, US Department of Health and Human Services, Washington, District of Columbia.

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September 2021

Becoming the Healthiest Nation: The Role of Healthy People 2030.

J Public Health Manag Pract 2021 Nov-Dec 01;27(Suppl 6):S218-S219

American Public Health Association, Washington, District of Columbia.

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September 2021

Flourishing After a Pandemic: Healthy People 2030.

J Public Health Manag Pract 2021 Nov-Dec 01;27(Suppl 6):S215-S217

Harvard T. H. Chan School of Public Health and Harvard Kennedy School, Boston, Massachusetts (Dr Koh); and Office of Disease Prevention and Health Promotion, US Department of Health and Human Services, Rockville, Maryland (Ms Blakey and Ms Ochiai).

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September 2021

Safety and efficacy of using heat-killed L-137: High-dose and long-term use effects on immune-related safety and intestinal bacterial flora.

J Immunotoxicol 2021 Dec;18(1):127-135

Ingredient Research Division, Research and Development Institute, House Wellness Foods Corp, Itami, Japan.

Heat-killed L-137 (HK L-137) promotes immune function in animals. In healthy people, T-cell proliferation was shown to be enhanced by taking 10 mg HK L-137 daily for 12 weeks. However, the safety and efficacy of higher doses or longer treatments have not yet been investigated in humans. Read More

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December 2021

Social Contagion of Vasovagal Symptoms in Blood Donors: Interactions With Empathy.

Ann Behav Med 2021 Sep 24. Epub 2021 Sep 24.

Department of Psychology, McGill University, Montreal, QC, Canada.

Background: Vasovagal reactions (VVRs) are commonly experienced in medical situations such as blood donation. Many believe that psychosocial contagion can contribute to the development of VVRs, but this is largely clinical lore.

Purpose: The goal of the present investigation was to examine the physiological effects of observing another experience a reaction, focusing on the potential moderating effects of empathy. Read More

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September 2021

Global trends and performances of Mediterranean diet: A bibliometric analysis in CiteSpace.

Medicine (Baltimore) 2021 Sep;100(38):e27175

Anhui University of Chinese Medicine, Anhui, China.

Background: The Mediterranean diet (MD) is an ancient eating habit that is believed to contribute to a healthy lifestyle. Unsurprisingly, research on the MD is growing rapidly as people pay more attention to health preservation and prevention, treatment and rehabilitation of chronic diseases. Previous reviews focused more on the effects of MD on a particular disease which has enhanced its significance in the medicine field. Read More

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September 2021

Diagnostic performance of the calcium/phosphate ratio for primary hyperparathyroidism in southwest China.

Endocr Connect 2021 Sep 1. Epub 2021 Sep 1.

G Li, Sichuan University West China Hospital, Chengdu, 610041, China.

Background: The diagnosis of primary hyperparathyroidism (PHPT) remains a challenge because of increased asymptomatic PHPT or patients with normocalcaemic PHPT (NPHPT). In addition, some primary hospitals in China have no equipment to measure PTH levels. Therefore, an additional, simple, and inexpensive laboratory biochemical marker is urgently needed. Read More

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September 2021

mHealth Interventions for Lifestyle and Risk Factor Modification in Coronary Heart Disease: Randomized Controlled Trial.

JMIR Mhealth Uhealth 2021 Sep 24;9(9):e29928. Epub 2021 Sep 24.

Department of Prevention and Management, School of Medicine, Inha University Hospital, Inha University, Incheon, Republic of Korea.

Background: Self-management of lifestyle and cardiovascular disease risk factors is challenging in older patients with coronary heart disease (CHD). SMS text messaging could be a potential support tool for self-management and the most affordable and accessible method through a mobile phone. High-quality evidence had been lacking, and previous studies evaluated the effects of SMS text messaging on the subjective measures of short-term outcomes. Read More

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September 2021

Influencing factors of community empowerment for domestic waste prevention and management among people living in river basin: A scoping review.

Indian J Public Health 2021 Jul-Sep;65(3):302-306

Department of Community Health Nursing, Faculty of Nursing, Universitas Padjadjaran, Sumedang, West Java Indonesia, Asia, Indonesia.

Citarum River in West Java, Indonesia, is the most polluted river in the world which pollutes the ocean. This is caused by lack of community empowerment for domestic waste prevention and management. This study aimed to identify factors influencing community empowerment for domestic waste prevention and management, as well as the intervention for improvement. Read More

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September 2021

Abnormalities in normal-appearing white matter from which multiple sclerosis lesions arise.

Brain Commun 2021 10;3(3):fcab176. Epub 2021 Aug 10.

Biogen Digital Health, Biogen, Cambridge, MA 02142, USA.

Normal-appearing white matter is far from normal in multiple sclerosis; little is known about the precise pathology or spatial pattern of this alteration and its relation to subsequent lesion formation. This study was undertaken to evaluate normal-appearing white matter abnormalities in brain areas where multiple sclerosis lesions subsequently form, and to investigate the spatial distribution of normal-appearing white matter abnormalities in persons with multiple sclerosis. Brain MRIs of pre-lesion normal-appearing white matter were analysed in participants with new T2 lesions, pooled from three clinical trials: SYNERGY (NCT01864148; = 85 with relapsing multiple sclerosis) was the test data set; ASCEND (NCT01416181; = 154 with secondary progressive multiple sclerosis) and ADVANCE (NCT00906399; = 261 with relapsing-remitting multiple sclerosis) were used as validation data sets. Read More

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Associations between Disability in Activities of Daily Living and Social Capital aspects among older adults: a scoping review.

J Frailty Sarcopenia Falls 2021 Sep 1;6(3):119-130. Epub 2021 Sep 1.

University of West Attica, Department of Nursing, Athens, Greece.

Social capital aspects are playing an important role in activities of daily living (ADL) performance, thus on independent living. This paper was aimed to present an overview of the associations and adverse effects between social capital aspects and disability in ADL and health-related quality of life (HRQoL) in an older population aged 65 years old and over. Α scoping review was designed following the guidelines of PRISMA Extension for Scoping Reviews (PRISMA-ScR) and the review was conducted by 3 authors. Read More

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September 2021

Oxidative Stress and Its Related Factors in Latent Autoimmune Diabetes in Adults.

Biomed Res Int 2021 13;2021:5676363. Epub 2021 Sep 13.

NHC Key Laboratory of Hormones and Development, Tianjin Key Laboratory of Metabolic Diseases, Chu Hsien-I Memorial Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin 300134, China.

Aims: Few research was reported to explore oxidative stress in individuals with latent autoimmune diabetes in adults (LADA). Therefore, our goal is to study oxidative stress and related factors in LADA patients.

Methods: In this study, 250 Chinese inpatients were diagnosed with LADA ( = 110) and type 2 diabetes mellitus ( = 140) and 140 healthy volunteers were recruited. Read More

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September 2021

Choriocapillaris Ischemia at the Leakage Point of Patients With Acute Central Serous Chorioretinopathy.

Front Med (Lausanne) 2021 7;8:675876. Epub 2021 Sep 7.

Zibo Central Hospital, Binzhou Medical University, Zibo, China.

We aimed to determine ischemia of the choriocapillaris at the leakage point of patients with acute central serous chorioretinopathy (CSC) by optical coherence tomographic angiography (OCTA). A retrospective study of 38 eyes of 38 acute CSC patients with spontaneous complete resolution of subretinal fluid (SRF) was conducted and patients were followed for 3 months. Fundus fluorescein angiography (FFA) and indocyanine green angiography (ICGA) were performed at baseline. Read More

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September 2021

Aesthetic-functional reconstruction of dental fracture and its impact on the psychosocial aspect.

Int J Burns Trauma 2021 15;11(4):328-336. Epub 2021 Aug 15.

Postgraduate Program, School of Dentistry, Fluminense Federal University Niterói, RJ, Brazil.

Traumatic dental injury (TDI) constitutes a public health concern. This injury occurs mainly in anterior teeth and brings disadvantageous psychosocial consequences that affect adolescents, as well as impairing their speech and eating habits. A healthy smile and facial aesthetic have an influence on social interaction, especially in the way individuals are seen, felt, and perceived by other people. Read More

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What Influences the Sustainable Food Consumption Behaviours of University Students? A Systematic Review.

Int J Public Health 2021 7;66:1604149. Epub 2021 Sep 7.

Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.

Global environmental challenges demand sustainable behaviours and policies to protect human and planetary health. We aimed to summarize the evidence about the factors related to Sustainable Food Consumption (SFC) behaviours of university students, and to propose an operational categorization of SFC behaviours. Seven databases were searched for observational studies evaluating Sustainable Food Consumption (SFC) among university students and that reported at least one behavioural outcome measure. Read More

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September 2021

Estimated Prevalence and Number of PiMZ Genotypes of Alpha-1 Antitrypsin in Seventy-Four Countries Worldwide.

Int J Chron Obstruct Pulmon Dis 2021 17;16:2617-2630. Epub 2021 Sep 17.

Pneumology Department, Hospital Universitari Vall d'Hebron/Vall d'Hebron Research Institute (VHIR), Vall d'Hebron Barcelona Hospital Campus, CIBER de Enfermedades Respiratorias (CIBERES), Barcelona, Spain.

Background: The α-1 antitrypsin (AAT) protease inhibitor PiMZ is a moderately deficient genotype, until recently considered of little or negligible risk. However, a growing number of studies show that MZ carriers have an increased risk of developing lung and liver diseases, if exposed to smoking or other airborne or industrial pollutants, and hepatotoxic substances.

Methods: We used the epidemiological studies performed to determine the frequencies of PiM and PiZ worldwide, based on the following criteria: 1) samples representative of the general population; 2) AAT phenotyping or genotyping characterized by adequate methods, including isoelectric focusing and polymerase chain reaction; and 3) studies with reliable results assessed with a coefficient of variation calculated from the sample size and 95% confidence intervals, to measure the precision of the results in terms of dispersion of the data around the mean. Read More

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September 2021

Quantitative Analysis of the Olfactory System in COVID-19: An MR Imaging Study.

AJNR Am J Neuroradiol 2021 Sep 23. Epub 2021 Sep 23.

Department of Radiology (S.M.E), Istanbul University Faculty of Medicine, Istanbul, Turkey.

Background And Purpose: Anosmia or hyposmia, often accompanied by changes in taste, is recognized as a common symptom that can assist in the diagnosis of coronavirus disease 2019 (COVID-19). The pathogenesis of olfactory dysfunction in COVID-19 is not yet fully understood. MR imaging represents a useful anatomic imaging method for the evaluation of olfactory dysfunction associated with varying etiologies, including viral infection, trauma, and neurodegenerative processes. Read More

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September 2021

Serum lncRNA-ANRIL and SOX9 expression levels in glioma patients and their relationship with poor prognosis.

World J Surg Oncol 2021 Sep 23;19(1):287. Epub 2021 Sep 23.

Department of Neurosurgery, Guangrao County People's Hospital, No. 180 Huayuan Road, Dongying, Guangrao County, 257300, P.R. China.

Background: lncRNA-CDKN2B antisense RNA 1 (ANRIL) and SRY-box transcription factor 9 (SOX9) has abnormal expression in many tumors including glioma, but the underlying molecular mechanism is unclear. This study set out to investigate the serum lncRNA-ANRIL and SOX9 levels in glioma patients and their effects on prognosis.

Methods: We enrolled 142 glioma patients admitted to our hospital from May 2014 to May 2016 into the research group (RG) and 120 healthy subjects receiving concurrent physical examinations into the control group (CG). Read More

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September 2021

Association Study of Polymorphisms in Neuronal Nicotinic Acetylcholine Receptor Subunit Genes With Schizophrenia in the Han Chinese Population.

Psychiatry Investig 2021 Sep 27. Epub 2021 Sep 27.

Department of Psychiatry, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Objective: To investigate the relation between nicotinic acetylcholine receptor subunit (nAChR) genes and schizophrenia, and the relation between tag single nucleotide polymorphism (rs1317286, rs1044396, rs6494212, rs16969968, and rs684513) and schizophrenia in Han Chinese people.

Methods: The protein-protein interaction (PPI) network among nAChR protein and 350 proteins encoded by schizophrenia-related susceptibility genes was constructed through the String database to explore whether nAChR genes were associated with schizophrenia in these known databases. Then, five single nucleotide polymorphisms (SNPs) of CHRNA3 (rs1317286), CHRNA4 (rs1044396), CHRNA7 (rs6494212), and CHRNA5 (rs16969968, rs684513) were analyzed in a sample of 1,035 schizophrenic patients and 816 healthy controls. Read More

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September 2021

Resilience and its associated factors among older disaster survivors.

Geriatr Nurs 2021 Sep 20;42(6):1264-1274. Epub 2021 Sep 20.

Faculty of Nursing, Prince of Songkla University, Thailand. Electronic address:

Resilience is a valuable resource in attaining a productive life as well as successful and healthy aging. Little is known about how older people who have experienced the impacts of disasters have fared, especially after earthquakes, in the long term. This cross-sectional analytical study aimed to identify resilience and its associated factors among 324 older disaster survivors. Read More

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September 2021

Effects of different high-flow nasal cannula flow rates on swallowing function.

Clin Biomech (Bristol, Avon) 2021 Sep 6;89:105477. Epub 2021 Sep 6.

Department of Physical Therapy, Nagasaki University Graduate School of Biomedical Sciences, Japan. Electronic address:

Background: High-flow nasal cannula therapy is used as a noninvasive treatment for people with acute respiratory disease. The aim of this study was to assess the impact of high-flow nasal cannula different flow rates on different characteristics of swallowing in healthy volunteers.

Methods: A prospective cohort study where healthy adult volunteers were subject to high-flow nasal cannula at different flow rates (0, 10, 20, 30, 40, and 50 L/min, in random order). Read More

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September 2021

Contemporary antiretrovirals and body-mass index: a prospective study of the RESPOND cohort consortium.

Lancet HIV 2021 Sep 20. Epub 2021 Sep 20.

ViiV Healthcare, Research Triangle, NC, USA.

Background: Weight gain effects of individual antiretroviral drugs are not fully understood. We investigated associations between a prespecified clinically significant increase (>7%) in body-mass index (BMI) and contemporary antiretroviral use.

Methods: The International Cohort Consortium of Infectious Diseases (RESPOND) is a prospective, multicohort collaboration, including data from 17 well established cohorts and over 29 000 people living with HIV. Read More

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September 2021

Speckle tracking imaging combined with myocardial comprehensive index to evaluate left ventricular function changes in patients with systemic lupus erythematosus.

Echocardiography 2021 Sep 23. Epub 2021 Sep 23.

Department of Ultrasonography, First Affiliated Hospital, School of Medicine, Shihezi University, Shihezi, China.

Objective: To evaluate early changes in left ventricular systolic function in patients with systemic lupus erythematosus (SLE) using three-dimensional speckle tracking imaging (3D-STI).

Methods: A total of 30 SLE patients and 30 healthy people (control group) were selected, the patients were further divided into subgroups according to their Safety of Estrogens in Lupus Erythematosus National Assessment version of the SLE Disease Activity Index (SELENA-SLEDAI) score: ≤ 12: mild-to-moderate group; > 12: severe group. All participants were examined using 3D-STI, the 3D-STI parameters were obtained. Read More

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September 2021

Comparative Effectiveness of Moderna, Pfizer-BioNTech, and Janssen (Johnson & Johnson) Vaccines in Preventing COVID-19 Hospitalizations Among Adults Without Immunocompromising Conditions - United States, March-August 2021.

MMWR Morb Mortal Wkly Rep 2021 Sep 24;70(38):1337-1343. Epub 2021 Sep 24.

Three COVID-19 vaccines are authorized or approved for use among adults in the United States (1,2). Two 2-dose mRNA vaccines, mRNA-1273 from Moderna and BNT162b2 from Pfizer-BioNTech, received Emergency Use Authorization (EUA) by the Food and Drug Administration (FDA) in December 2020 for persons aged ≥18 years and aged ≥16 years, respectively. A 1-dose viral vector vaccine (Ad26. Read More

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September 2021

Short Sleep Duration Among Infants, Children, and Adolescents Aged 4 Months-17 Years - United States, 2016-2018.

MMWR Morb Mortal Wkly Rep 2021 Sep 24;70(38):1315-1321. Epub 2021 Sep 24.

Infants, children, and adolescents who do not get sufficient sleep are at increased risk for injuries, obesity, type 2 diabetes, poor mental health, attention and behavior problems, and poor cognitive development (1). The American Academy of Sleep Medicine (AASM) provides age-specific sleep duration recommendations to promote optimal health (1). CDC analyzed data from the 2016-2018 National Survey of Children's Health (NSCH) to assess the prevalence of short sleep duration among persons in the United States aged 4 months-17 years. Read More

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September 2021