3,191 results match your criteria healthy lambs


Nampt affects mitochondrial function in aged oocytes by mediating the downstream effector FoxO3a.

J Cell Physiol 2021 Jul 28. Epub 2021 Jul 28.

National Engineering Laboratory for Animal Breeding, Beijing Key Laboratory for Animal Genetic Improvement, College of Animal Science and Technology, China Agricultural University, Beijing, China.

Maternal aging can impair the quality and decrease the developmental competence of ovulated oocytes. In this study, compromised germinal vesicle breakdown (GVBD) was found in aged mice oocytes. Furthermore, we observed increased reactive oxygen species (ROS) and mitochondrial Ca levels, along with reduced mitochondrial temperature in aged oocytes. Read More

View Article and Full-Text PDF

Dental biofilm and its ecological interrelationships in ovine periodontitis.

J Med Microbiol 2021 Jul;70(7)

Department of Production and Animal Health, School of Veterinary Medicine, São Paulo State University (Unesp), Araçatuba Campus, São Paulo, Brazil.

Periodontitis, one of the most common oral disorders in sheep, is caused by a mixed and opportunistic microbiota that severely affects the health and welfare of animals. However, little is known about the ecological processes involved and the composition of the microbiota associated with the development of the disease. Using high-throughput sequencing of the 16S ribosomal RNA gene and network analysis it would be possible to discriminate the microbiomes of clinically healthy sheep and those with periodontitis and possibly identify the key microorganisms associated with the disease. Read More

View Article and Full-Text PDF

Effect of ketoprofen and tolfenamic acid on intravenous pharmacokinetics of ceftriaxone in sheep.

J Vet Pharmacol Ther 2021 Jul 26. Epub 2021 Jul 26.

Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Selcuk, Konya, Turkey.

In this study, the pharmacokinetics of ceftriaxone (40 mg/kg) was determined following a single intravenous (IV) administration of ceftriaxone alone and co-administration with ketoprofen (3 mg/kg) or tolfenamic acid (2 mg/kg) in sheep. Eight healthy Akkaraman sheep (2.4 ± 0. Read More

View Article and Full-Text PDF

Role of biometals in activation of immune cum inflammatory response in ovine ageing eye: a potential model for understanding human geriatric eye diseases.

Biometals 2021 Jul 23. Epub 2021 Jul 23.

Department of General Surgery, SKIMS Medical College, Srinagar, Jammu and Kashmir, 190001, India.

The present study was designed to evaluate the age-related changes in biometal and antimicrobial peptide (cathelicidin) concentration and their role in oxidative cum pro-inflammatory cascade in an ovine animal model. Clinically healthy ovine (n = 126) were grouped as Group I (n = 55, age = up to 3 years), Group II (n = 52, age = above 3-below 6 years) and Group III (n = 19, age = 6 years above). Samples (aqueous humour and lens of the eye) were collected stored at - 80 °C till further analysis. Read More

View Article and Full-Text PDF

Morphometrical, histological, and scanning electron microscopic investigations on the hard palate of Rahmani sheep (Ovis aries).

Microsc Res Tech 2021 Jul 26. Epub 2021 Jul 26.

Department of Anatomy and Embryology, Faculty of Veterinary Medicine, South Valley University, Qena, Egypt.

The present study investigated the hard palate of Rahmani sheep (Ovis aries). Samples from nine healthy adult male sheep were investigated using morphometrical, histological and scanning electron microscopic examination. Morphologically, the hard palate was elongated, narrow rostrally, and wide caudally. Read More

View Article and Full-Text PDF

Occupational Practices and Hazards of Rural Livestock Keepers in Uganda: A Cross-Sectional Study.

East Afr Health Res J 2018 1;2(1):67-77. Epub 2018 Apr 1.

Center for One Health Research, University of Washington, Seattle, Washington, USA.

Objective: In Uganda, 70% of rural poor rely on livestock for subsistence, to meet social obligations, and to insure against disaster. Livestock farming in Africa is in a state of transition from traditional management systems toward intensified modern systems, calling into question the future of traditional systems. To inform this debate, we conducted a survey in Moyo District, Uganda, to describe occupational practices and hazards of agropastoralist livestock keepers. Read More

View Article and Full-Text PDF

Sequencing and High-Contiguity Genome Assembly of Reveals Its Specific Fatty Acid Metabolism and Reproductive Stem Cell Regulatory Network.

Front Cell Infect Microbiol 2021 6;11:693914. Epub 2021 Jul 6.

Key Laboratory of Bio-Resources and Eco-Environment (Ministry of Education), College of Life Sciences, Sichuan University, Chengdu, China.

() parasitizes the small intestine of sheep and causes inhibited growth and development or even death. Being globally distributed, it causes considerable economic losses to the animal husbandry industry. Here, using Illumina, PacBio and BioNano techniques, we obtain a high-quality genome assembly of , which has a total length of 142 Mb, a scaffold N50 length of 7. Read More

View Article and Full-Text PDF

Airway diameter at different transpulmonary pressures in ex vivo sheep lungs: Implications for deep-inspiration-induced bronchodilation and bronchoprotection.

Am J Physiol Lung Cell Mol Physiol 2021 07 21. Epub 2021 Jul 21.

The UBC Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, BC, Canada.

Deep inspiration (DI)-induced bronchodilation is the first line of defense against bronchoconstriction in healthy subjects. A hallmark of asthma is the lack of this beneficial effect of DI. The mechanism underlying the bronchodilatory effect of DI is not clear. Read More

View Article and Full-Text PDF

Blunted natriuretic response to saline loading in sheep with hypertensive kidney disease following radiofrequency catheter-based renal denervation.

Sci Rep 2021 Jul 20;11(1):14795. Epub 2021 Jul 20.

Cardiovascular Program, Monash Biomedicine Discovery Institute and Department of Physiology, Monash University, Clayton, Melbourne, VIC, 3800, Australia.

Renal sympathetic nerves contribute to renal excretory function during volume expansion. We hypothesized that intact renal innervation is required for excretion of a fluid/electrolyte load in hypertensive chronic kidney disease (CKD) and normotensive healthy settings. Blood pressure, kidney hemodynamic and excretory response to 180 min of isotonic saline loading (0. Read More

View Article and Full-Text PDF

The combinations of sulfur and molybdenum fertilizations improved antioxidant capacity of grazing Guizhou semi-fine wool sheep under copper and cadmium stress.

Ecotoxicol Environ Saf 2021 Jul 17;222:112520. Epub 2021 Jul 17.

State Key Laboratory of Sheep Genetic Improvement and Healthy Production, Xinjiang Academy of Agricultural and Reclamation Sciences, Shihezi, China.

Mineral development and metal smelting are the main sources of heavy metal pollution, and copper (Cu) and cadmium (Cd) are the most serious mineral elements in heavy metal pollution. Food chain is the main channel for Cu and Cd to enter human body. Excessive accumulation of Cu and Cd can lead to a variety of diseases and threaten human health. Read More

View Article and Full-Text PDF

Molecular investigation and phylogeny of Theileria spp. from naturally infected sheep and the first report of Theileria sp. OT3 in Sulaymaniyah governorate/Iraq.

Pol J Vet Sci 2021 Jun;24(2):201-209

Department of Microbiology, College of Medicine, University of Sulaimani, Madame Mitterrand, Sulaymaniyah 46001, Kurdistan Region, Iraq.

Theileriosis is a significant hemoprotozoal disease of domestic and wild ruminants in tropical and subtropical regions of the world. Ovines are mainly infected by T. ovis and T. Read More

View Article and Full-Text PDF

Effects of mannan oligosaccharides on growth performance, nutrient digestibility, ruminal fermentation and hematological parameters in sheep.

PeerJ 2021 30;9:e11631. Epub 2021 Jun 30.

Gansu Agricultural University, Lanzhou, China.

Background: Mannan oligosaccharides (MOS) are a promising feed additive in animal husbandry due to mainly improving animal health status. The purpose of this study was to investigate the effects of MOS on growth performance, nutrient digestibility, ruminal fermentation, and twelve hematological parameters in sheep.

Methods: Ninety-six healthy rams with similar body weights were chosen and divided into four treatment groups (twenty-four rams in each group), in which four different doses of MOS were tested: 0%, 0. Read More

View Article and Full-Text PDF

A Trifecta of New Insights into Ovine Footrot for Infection Drivers, Immune Response and Host Pathogen Interactions.

Infect Immun 2021 Jul 6:IAI0027021. Epub 2021 Jul 6.

School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, Loughborough, Leicestershire, LE12 5RD.

Footrot is a polymicrobial infectious disease in sheep causing severe lameness, leading to one of the industry's biggest welfare problems. The complex aetiology of footrot makes in-situ or in-vitro investigations difficult. Computational methods offer a solution to understanding the bacteria involved, how they may interact with the host and ultimately providing a way to identify targets for future hypotheses driven investigative work. Read More

View Article and Full-Text PDF

Multidrug resistance IncC plasmid carrying bla in Shiga toxin-producing Escherichia coli ST215-H54 of ovine origin.

Infect Genet Evol 2021 Jul 1;93:104989. Epub 2021 Jul 1.

Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, São Paulo, Brazil. Electronic address:

CMY-type β-lactamases are the most reported plasmid-mediated AmpC (pAmpC), with the CMY-2-like group being the most clinically relevant described in Escherichia coli at human-animal-environment interface. Shiga toxin-producing E. coli (STEC) lineages are zoonotic pathogens commonly reported causing serious clinical conditions in humans, including severe diarrheagenic diseases. Read More

View Article and Full-Text PDF

An empirical investigation of deviations from the Beer-Lambert law in optical estimation of lactate.

Sci Rep 2021 Jul 2;11(1):13734. Epub 2021 Jul 2.

Research Centre for Biomedical Engineering (RCBE), School of Mathematics, Computer Science and Engineering, City, University of London, Northampton Square, London, EC1V 0HB, UK.

The linear relationship between optical absorbance and the concentration of analytes-as postulated by the Beer-Lambert law-is one of the fundamental assumptions that much of the optical spectroscopy literature is explicitly or implicitly based upon. The common use of linear regression models such as principal component regression and partial least squares exemplifies how the linearity assumption is upheld in practical applications. However, the literature also establishes that deviations from the Beer-Lambert law can be expected when (a) the light source is far from monochromatic, (b) the concentrations of analytes are very high and (c) the medium is highly scattering. Read More

View Article and Full-Text PDF

Optimising Large Animal Models of Sustained Atrial Fibrillation: Relevance of the Critical Mass Hypothesis.

Front Physiol 2021 15;12:690897. Epub 2021 Jun 15.

Unit of Cardiac Physiology, Institute of Cardiovascular Sciences, Manchester Academic Health Sciences Centre, The University of Manchester, Manchester, United Kingdom.

Background: Large animal models play an important role in our understanding of the pathophysiology of atrial fibrillation (AF). Our aim was to determine whether prospectively collected baseline variables could predict the development of sustained AF in sheep, thereby reducing the number of animals required in future studies. Our hypothesis was that the relationship between atrial dimensions, refractory periods and conduction velocity (otherwise known as the critical mass hypothesis) could be used for the first time to predict the development of sustained AF. Read More

View Article and Full-Text PDF

Ticks and Tick-Borne Pathogens Associated with Dromedary Camels () in Northern Kenya.

Microorganisms 2021 Jun 30;9(7). Epub 2021 Jun 30.

International Centre of Insect Physiology and Ecology (icipe), Nairobi P.O. Box 30772-00100, Kenya.

Ticks and tick-borne pathogens (TBPs) are major constraints to camel health and production, yet epidemiological data on their diversity and impact on dromedary camels remain limited. We surveyed the diversity of ticks and TBPs associated with camels and co-grazing sheep at 12 sites in Marsabit County, northern Kenya. We screened blood and ticks (858 pools) from 296 camels and 77 sheep for bacterial and protozoan TBPs by high-resolution melting analysis and sequencing of PCR products. Read More

View Article and Full-Text PDF

Influence of the Production System (Intensive vs. Extensive) at Farm Level on Proximate Composition and Volatile Compounds of Portuguese Lamb Meat.

Foods 2021 Jun 22;10(7). Epub 2021 Jun 22.

Centro Tecnológico de la Carne de Galicia, Avd. Galicia No 4, Parque Tecnológico de Galicia, San Cibrao das Viñas, 32900 Ourense, Spain.

Today's society demands healthy meat with a special emphasis on integrated animal husbandry combined with the concern for animal welfare. In this sense, the raising of lambs in an extensive system has been one of the most common practices, which results in meats with high nutritional value. However, both the production system and the diet play a fundamental role in the chemical composition of the meat, which has a direct impact on the content of volatile compounds. Read More

View Article and Full-Text PDF

Platelet and White Cell Reactivity to Top-Load Intravenous Perfluorocarbon Infusion in Healthy Sheep.

J Surg Res 2021 Jun 27;267:342-349. Epub 2021 Jun 27.

Department of Anesthesiology, University of Florida College of Medicine, Gainesville, Florida 32610.

Background: Perfluorocarbon emulsions (PFCs) are intravenous artificial oxygen carriers with enhanced gas solubility. As lipid micelle nanoparticle emulsions, PFCs may have a class effect that causes degrees of thrombocytopenia. Understanding the extent of the platelet effects, including mechanism and potential inflammation after PFC infusion, is important for safe human trials. Read More

View Article and Full-Text PDF

Effect of dietary protein on growth performance, and serum biochemical index in late pregnant Hu ewes and their offspring.

Anim Biotechnol 2021 Jun 30:1-9. Epub 2021 Jun 30.

Hunan International Joint Laboratory of Animal Intestinal Ecology and Health, Laboratory of Animal Nutrition and Human Health, College of Life Sciences, Hunan Normal University, Changsha, China.

The purpose of this study was to investigate the effects of different protein levels in late pregnancy on ewe and lamb growth performance, serum biochemical indexes. Thirty-three ewes (46.4 ± 1. Read More

View Article and Full-Text PDF

CRISPR-Cas13a-Based Detection for Bovine Viral Diarrhea Virus.

Front Vet Sci 2021 9;8:603919. Epub 2021 Jun 9.

College of Life Sciences, Shihezi University, Shihezi, China.

Bovine Viral Diarrhea Virus (BVDV) is the main pathogen of bovine viral diarrhea disease (BVD), which leads to enormous economic losses in the cattle industry. A sensitive and specific detection for BVDV is advantageous to the control of BVDV. Clustered regularly interspaced short palindromic repeats (CRISPR)-Cas systems have been used for detecting virus RNA. Read More

View Article and Full-Text PDF

Molecular detection and characterization of ovine herpesvirus-2 using heminested PCR in Pakistan.

J Vet Sci 2021 Jul 3;22(4):e51. Epub 2021 Jun 3.

Department of Zoology, Faculty of Sciences, PMAS-Arid Agriculture University, Rawalpindi 46000, Pakistan.

Background: Malignant catarrhal fever (MCF) is a highly fatal lymphoproliferative disease of cattle, deer, bison, water buffalo, and pigs caused by the gamma-herpesviruses alcelaphine herpesvirus-1 (AlHV-1) and ovine herpesvirus-2 (OvHV-2).

Objectives: This study aimed to determine the prevalence of OvHV-2 in sheep, goats, cattle, and buffalo in Rawalpindi and Islamabad, Pakistan, by applying molecular and phylogenetic methods.

Methods: Blood samples were aspirated from sheep (n = 54), goat (n = 50), cattle (n = 46) and buffalo (n= 50) at a slaughterhouse and several farms. Read More

View Article and Full-Text PDF

Clonal spread of O101: H9-ST10 and O101: H9-ST167 strains carrying and among diarrheal calves in a Chinese farm, with Australian as the possible origin of O101: H9-ST10.

Zool Res 2021 Jul;42(4):461-468

College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong 510642, China.

During a 2018 antimicrobial resistance surveillance of isolates from diarrheal calves in Xinjiang Province, China, an unexpectedly high prevalence (48.5%) of fosfomycin resistance was observed. This study aimed to reveal the determinants of fosfomycin resistance and the underlying transmission mechanism. Read More

View Article and Full-Text PDF

miR-509-5p anti-infection response for mycoplasma pneumonia in sheep by targeting NF-κB pathway.

Vet Immunol Immunopathol 2021 Aug 5;238:110275. Epub 2021 Jun 5.

College of Animal Science and Technology, Shihezi University, Shihezi, Xinjiang, China. Electronic address:

MicroRNAs play a key role in Mannan-binding lectin-mediated resistance to Mycoplasma ovipneumoniae pneumonia, by regulating the translation of mRNAs of target genes, thereby regulating the immune response. Additionally, TRAF6 is a key molecule in Toll-like receptor signal transduction, which mediates inflammation and apoptosis signaling pathways and is widely involved in inflammation and immune response. While the molecular regulation mechanism has not been reported. Read More

View Article and Full-Text PDF

Perceptions of pastoralist problems: A participatory study on animal management, disease spectrum and animal health priorities of small ruminant pastoralists in Georgia.

Prev Vet Med 2021 Aug 11;193:105412. Epub 2021 Jun 11.

State Laboratory of Agriculture, Tbilisi, Georgia. Electronic address:

Small ruminants support the livelihoods of millions of poor pastoralist and sedentary households around the world. While pastoralists are generally not amongst the poorest in terms of assets, they are frequently marginalised in terms of their access to political power, health and education. This study was undertaken among pastoralist households keeping small ruminants in four regions of the country of Georgia. Read More

View Article and Full-Text PDF

Species variations in tenocytes' response to inflammation require careful selection of animal models for tendon research.

Sci Rep 2021 Jun 14;11(1):12451. Epub 2021 Jun 14.

Department of Companion Animals and Horses, Equine Surgery Unit, University of Veterinary Medicine Vienna, VETERM, Veterinaerplatz 1, 1210, Vienna, Austria.

For research on tendon injury, many different animal models are utilized; however, the extent to which these species simulate the clinical condition and disease pathophysiology has not yet been critically evaluated. Considering the importance of inflammation in tendon disease, this study compared the cellular and molecular features of inflammation in tenocytes of humans and four common model species (mouse, rat, sheep, and horse). While mouse and rat tenocytes most closely equalled human tenocytes' low proliferation capacity and the negligible effect of inflammation on proliferation, the wound closure speed of humans was best approximated by rats and horses. Read More

View Article and Full-Text PDF

Effects of xenin-25 on insulin and glucagon secretions in healthy conscious sheep.

Domest Anim Endocrinol 2021 May 15;77:106635. Epub 2021 May 15.

Veterinary Physiology, Division of Biosciences, Department of Veterinary Medicine, School of Veterinary Medicine, Rakuno Gakuen University, 582 Bunkyodai-Midorimachi, Ebetsu, Hokkaido 069-8501, Japan.

The aim of present study was to determine effect of an intravenous injection of xenin-25 on insulin and glucagon secretion in healthy conscious sheep. After feeding once at 17:00, the experiment was started from 9:00 on the next day. Xenin-25 was intravenously (i. Read More

View Article and Full-Text PDF

Local and systemic inflammation after implantation of a novel iron based porous degradable bone replacement material in sheep model.

Sci Rep 2021 Jun 8;11(1):12035. Epub 2021 Jun 8.

Fraunhofer Institute for Manufacturing and Advanced Materials (IFAM), Dresden, Germany.

Despite the high potential of healthy bone to regenerate, the reconstruction of large bone defects remains a challenge. Due to the lack of mechanical stability of existing bone substitutes, recently developed degradable metallic alloys are an interesting alternative providing higher load-bearing capabilities. Degradable iron-based alloys therefore might be an attractive innovation. Read More

View Article and Full-Text PDF

A kinematic model-based analysis framework for 3D Cine-DENSE-validation with an axially compressed gel phantom and application in sheep before and after antero-apical myocardial infarction.

Magn Reson Med 2021 10 6;86(4):2105-2121. Epub 2021 Jun 6.

Veterans Affairs Medical Center, San Francisco, California, USA.

Purpose: Myocardial strain is increasingly used to assess left ventricular (LV) function. Incorporation of LV deformation into finite element (FE) modeling environment with subsequent strain calculation will allow analysis to reach its full potential. We describe a new kinematic model-based analysis framework (KMAF) to calculate strain from 3D cine-DENSE (displacement encoding with stimulated echoes) MRI. Read More

View Article and Full-Text PDF
October 2021

Effect of housing and nutritional interventions during winter on wool attributes of Corriedale sheep.

Trop Anim Health Prod 2021 Jun 7;53(3):348. Epub 2021 Jun 7.

Faculty of Veterinary Sciences and Animal Husbandry, Sher-E-Kashmir University of Agricultural Sciences and Technology-Kashmir, Srinagar, 190006, J&K, India.

There are several factors that can directly or indirectly influence wool quality and quantity in sheep, the main elements being genetic and environmental factors. An experiment was conducted to assess the effect of different management/housing interventions during winter on wool quality and yield in Corriedale ewes. Forty healthy pregnant ewes were selected and divided into four groups (G, G, G, G) based on their body weight and parity. Read More

View Article and Full-Text PDF