495,762 results match your criteria health state


Increase in SARS-CoV-2 infected biomedical waste among low middle-income countries: environmental sustainability and impact with health implications.

J Basic Clin Physiol Pharmacol 2021 Jul 22. Epub 2021 Jul 22.

Department of Anatomical Sciences, School of Medicine and Allied Health Sciences, University of the Gambia, Serekunda, The Gambia.

Studies have shown that severe acute respiratory syndrome corona virus-2 (SARS-CoV-2) is a highly infectious disease, with global deaths rising to about 360,438 as of 28 May 2020. Different countries have used various approaches such as lockdown, social distancing, maintenance of personal hygiene, and increased establishment of testing and isolation centers to manage the pandemic. Poor biomedical waste (BMW) management, treatment, and disposal techniques, especially SARS-CoV-2 infected BMW, may threaten the environmental and public health in most developing countries and, by extension, impact the economic status of individuals and the nation at large. Read More

View Article and Full-Text PDF

Adverse childhood experiences and trauma informed care: treating the whole patient with a more complete osteopathic approach.

Authors:
T Brian Marcoux

J Osteopath Med 2021 Jul 22. Epub 2021 Jul 22.

Division of Child & Adolescent Psychiatry, The Johns Hopkins Hospital, 1800 Orleans St, Baltimore, MD21287-0010, USA.

In 1998, a seminal study identified a strong connection between participants' exposures to adverse childhood experiences (ACEs) and the development of risk factors for serious health conditions later in life. More than two decades later, leaders in both policy and health care professions now appreciate the impact of social determinants of health, including the enormous societal costs incurred by deleterious experiences, and recognize that treating illness begins with prevention in early childhood. The trauma informed care (TIC) model offers a treatment approach that lends consideration to the traumatic experiences that impact a given patient and allows for more complete treatment by their physician. Read More

View Article and Full-Text PDF

Validation of the Mini-Addenbrooke's Cognitive Examination in Mild Cognitive Impairment in Arabic Speakers.

Dement Geriatr Cogn Disord 2021 Jul 22:1-5. Epub 2021 Jul 22.

Geriatrics and Gerontology Department, Ain Shams University, Cairo, Egypt.

Introduction: Mild cognitive impairment (MCI) represents a target for early detection and intervention in dementia, yet there is a shortage of validated screening tools in Arabic to diagnose MCI. The mini-Addenbrooke's Cognitive Examination (m-ACE) is a brief cognitive battery that is scored out of 30 and can be administered in under 5 min providing a quick screening tool for assessment of cognition.

Objective: We aimed to validate the m-ACE in Arabic speakers in Egypt with MCI to provide cut-off scores. Read More

View Article and Full-Text PDF

Synthetic pulmonary perfusion images from 4DCT for functional avoidance using deep learning.

Phys Med Biol 2021 Jul 22. Epub 2021 Jul 22.

Radiation Oncology, Beaumont Health System, Royal Oak, Michigan, UNITED STATES.

Purpose: To develop and evaluate the performance of a deep learning model to generate synthetic pulmonary perfusion images from clinical 4DCT images for patients undergoing radiotherapy for lung cancer.

Methods: A clinical data set of 58 pre- and post-radiotherapy 99mTc-labelled MAA-SPECT perfusion studies (32 patients) each with contemporaneous 4DCT studies was collected. Using the inhale and exhale phases of the 4DCT, a 3D-Residual Network was trained to create synthetic perfusion images utilizing the MAA-SPECT as ground truth. Read More

View Article and Full-Text PDF

B-prolymphocytic leukemia: Is it time to retire this entity?

Ann Diagn Pathol 2021 Jul 16;54:151790. Epub 2021 Jul 16.

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America. Electronic address:

B-prolymphocytic leukemia (B-PLL) is included as a distinct entity in the current World Health Organization classification of hematolymphoid neoplasms. However, the diagnosis of B-PLL has presented several challenges since its conception, and over the past decades investigations of B-PLL have revealed substantial biologic and molecular heterogeneity. These data have shown that many B-PLL cases present many similarities with other types of small B-cell lymphomas, and that small B-cell lymphomas can undergo prolymphocytoid transformation. Read More

View Article and Full-Text PDF

Differences in emotional state and autistic symptoms before and during confinement due to the COVID-19 pandemic.

Res Dev Disabil 2021 Jul 16;116:104038. Epub 2021 Jul 16.

Department of Health Psychology, Miguel Hernández University of Elche, Edificio Altamira, Avda. de la Universidad, s/n Elche, Alicante, 03202, Spain.

Background: The COVID-19 pandemic has generated a global crisis that has affected the emotional health of both the general and the clinical population.

Method: The present study aimed to analyze the differences between the emotional states of a group of individuals with ASD and a neurotypical group both during and after the COVID-19 confinement. The study also examined the changes in autistic symptoms between a group of individuals with ASD who were confined during the COVID-19 pandemic and another group of individuals with ASD who were studied prior to the COVID-19 pandemic period. Read More

View Article and Full-Text PDF

Mapping groundwater-dependent ecosystems in arid Central Asia: Implications for controlling regional land degradation.

Sci Total Environ 2021 Jul 14;797:149027. Epub 2021 Jul 14.

Eurasia Institute of Earth Sciences, Istanbul Technical University, Maslak, Istanbul 34469, Turkey.

Groundwater-dependent ecosystems (GDEs) exist all over the world, especially in water-limited regions. To achieve better water management, it is necessary to map and identify GDEs. Central Asia (CA) is one of the most arid regions in the mid-latitudes and one of the major regions with shallow groundwater tables. Read More

View Article and Full-Text PDF

Male involvement in promotion of safe motherhood in low- and middle-income countries: A scoping review.

Midwifery 2021 Jul 14;103:103089. Epub 2021 Jul 14.

Centre for Midwifery, Maternal & Perinatal Health, Faculty of Health and Social Sciences, Bournemouth University, 10 St Paul's Ln, Boscombe BH8 8AJ, United Kingdom. Electronic address:

Background: Maternal health programmes that focus on the woman alone are limiting in LMICs as pregnant women often relate to maternity services through a complex social web that reflects power struggles within the kinship and the community.

Methods: A scoping review was conducted to explore the rationale for male involvement in maternal health in LMICs. This review was guided by the question: What is the current state of knowledge regarding the inclusion of men in maternal health services in LMICs? The literature search was conducted using mySearch, Bournemouth University`s iteration of the EBSCO Discovery Service (EDS) tool. Read More

View Article and Full-Text PDF

Blood volatile organic aromatic compounds concentrations across adulthood in relation to total and cause specific mortality: A prospective cohort study.

Chemosphere 2021 Jul 16;286(Pt 1):131590. Epub 2021 Jul 16.

Department of Occupational & Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China; Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China. Electronic address:

Objective: We aimed to evaluate the relationship between blood volatile organic aromatic compounds (VOACs) across adulthood and mortality.

Methods: A total of 16,968 participants from the National health and Nutrition Examination Surveys (NHANES 1988-1994 and 1999-2014) were included in the present study. Cox proportional hazards models were used to explore the associations between VOACs and total or cause-specific mortality. Read More

View Article and Full-Text PDF

Biomass as source for hydrochar and biochar production to recover phosphates from wastewater: A review on challenges, commercialization, and future perspectives.

Chemosphere 2021 Jul 15;286(Pt 1):131490. Epub 2021 Jul 15.

Department of Food, Agricultural and Biological Engineering, The Ohio State University, Wooster, OH, United States. Electronic address:

Excessive phosphate run-off with total phosphorus concentration greater than 20 μg P L triggers the growth of harmful algal species in waterbodies and potentially leads to eutrophication. This has severe negative implications on aquatic environment and impacts human health. The annual economic impact of harmful algal blooms is reported to be as high as $25 million for public health and commercial fishery sector, $29 million for recreation/tourism sector and $2 million for monitoring and management. Read More

View Article and Full-Text PDF

"LIMITED" EXTREME LATERAL INFRAJUGULAR TRANSCONDYLAR-TRANSTUBERCULAR EXPOSURE (ELITE) FOR THE MICROSURGICAL MANAGEMENT OF C1-C2 SCHWANNOMA: OPERATIVE VIDEO.

World Neurosurg 2021 Jul 19. Epub 2021 Jul 19.

Department of Neurosurgery, San Filippo Neri Hospital/ASLRoma1, Rome, Italy; Department of Neurosurgery, The State Education Institution of Higher Professional Training, The First Sechenov Moscow State Medical University under Ministry of Health, Russian Federation. Electronic address:

View Article and Full-Text PDF

The Effects of Chronic Lymphocytic Thyroiditis on Clinicopathological Factors In Papillary Thyroid Cancer.

Endocr Pract 2021 Jul 19. Epub 2021 Jul 19.

Department of Endocrinology and Metabolism, University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey.

Introduction: This study evaluated the impact of chronic lymphocytic thyroiditis (CLT) on clinicopathological parameters, prognostic outcome and initial treatment responses in patients with papillary thyroid cancer (PTC).

Methods: A retrospective review was made of 1409 patients with PTC, comprising 443 pathology proven PTC patients with CLT and 447 PTC patients without CLT.

Results: The median follow-up time was 58 (8-380) months and the median age at the time of diagnosis was 43 years. Read More

View Article and Full-Text PDF

Relationship of proprioception, cutaneous sensitivity, and muscle strength with the balance control among older adults.

J Sport Health Sci 2021 Jul 19. Epub 2021 Jul 19.

Key Laboratory of Exercise and Health Sciences of Ministry of Education, Shanghai University of Sport, Shanghai 200438, China; Department of Health Sciences and Kinesiology, Georgia Southern University, Statesboro, GA 30460, USA. Electronic address:

Purpose: Balance impairment is one of the strongest risk factors for falls. Proprioception, cutaneous sensitivity, and muscle strength are 3 important contributors to balance control in older adults. The relationship that dynamic and static balance control has to proprioception, cutaneous sensitivity, and muscle strength is still unclear. Read More

View Article and Full-Text PDF

Population seroprevalence of SARS-CoV-2 antibodies in Anambra state, South-East, Nigeria.

Int J Infect Dis 2021 Jul 19. Epub 2021 Jul 19.

State Ministry of Health, Jerome Udoji Secretariat Complex, Aroma Awka, Anambra State, Nigeria.

Objective: The objective of this study was to determine the proportion of Anambra State population that had been infected by the SARS-CoV-2 virus and developed antibodies before the second wave.

Methods: The WHO-recommended health facility-based cross-sectional approach was adapted for this survey. Between 8 and 15 December 2020, 3142 participants across the 21 local government areas (LGAs) of the state, aged one year and over, attending randomly selected health facilities were recruited. Read More

View Article and Full-Text PDF

Identification and molecular characterization of H9N2 viruses carrying multiple mammalian adaptation markers in resident birds in central-western wetlands in India.

Infect Genet Evol 2021 Jul 19:105005. Epub 2021 Jul 19.

ICAR- National Institute of High Security Animal Diseases, Bhopal 462022, India.

We report here a targeted risk-based study to investigate the presence of influenza A viruses at the migratory-wild-domestic bird interface across the major wetlands of central India's Maharashtra state during the winter migration season. The H9N2 viruses have been isolated and confirmed in 3.86% (33/854) of the fecal samples of resident birds. Read More

View Article and Full-Text PDF

Combining tumor deposits with the number of lymph node metastases to improve the prognostic accuracy in stage III colon cancer: a post hoc analysis of the CALGB/SWOG 80702 phase III study (Alliance).

Ann Oncol 2021 Jul 19. Epub 2021 Jul 19.

Department of Medical Oncology, Dana-Farber/Partners Cancer Care, Boston, MA, USA.

Background: In colon cancer, tumor deposits (TD) are considered in assigning prognosis and staging only in the absence of lymph node metastasis (i.e., stage III pN1c tumors). Read More

View Article and Full-Text PDF

Perinatal SSRI exposure disrupts G protein-coupled receptor BAI3 in developing dentate gyrus and adult emotional behavior: relevance to psychiatric disorders.

Neuroscience 2021 Jul 19. Epub 2021 Jul 19.

School of Neuroscience, Virginia Polytechnic Institute and State University, Blacksburg, VA, 24061, USA. Electronic address:

Selective serotonin reuptake inhibitor (SSRI) antidepressants are widely prescribed to pregnant women suffering with depression, although the long-term impact of these medications on exposed offspring are poorly understood. Perinatal SSRI exposure alters human offspring's neurodevelopment and increases risk for psychiatric illness in later life. Rodent studies suggest that perinatal SSRI-induced behavioral abnormalities are driven by changes in the serotonin system as well as epigenetic and transcriptomic changes in the developing hippocampus. Read More

View Article and Full-Text PDF

Dietary quality modifies the association between multimorbidity and change in mobility limitations among older Americans.

Prev Med 2021 Jul 19:106721. Epub 2021 Jul 19.

Department of Oncology, Dell Medical School, University of Texas at Austin, Austin, TX, USA.

To identify potentially modifiable risk-factors in the age-related disablement process, we examined the association between change in mobility limitations and multimorbidity and how dietary quality moderates this association. Information from 3320 adults aged 65 and older in 2012 was drawn from the Health and Retirement Study and the Health Care and Nutrition Study. Mobility limitations reported in 2012 and change in mobility limitations from 2012 to 2014 were regressed on multimorbidity measured as number of chronic conditions in 2012, dietary quality measured in 2013 using the Alternative Healthy Eating Index-2010 (AHEI-2010), and their interaction term using Poisson regression. Read More

View Article and Full-Text PDF

STRIDES - STudying Risk to Improve DisparitiES in Cervical Cancer in Mississippi - Design and baseline results of a Statewide Cohort Study.

Prev Med 2021 Jul 19:106740. Epub 2021 Jul 19.

National Cancer Institute, Clinical Genetics Branch, Division of Cancer Epidemiology & Genetics, Rockville, MD, United States of America. Electronic address:

Cervical cancer rates in Mississippi are disproportionately high, particularly among Black individuals; yet, research in this population is lacking. We designed a statewide, racially diverse cohort of individuals undergoing cervical screening in Mississippi. Here, we report the baseline findings from this study. Read More

View Article and Full-Text PDF

Timing, duration, and differential susceptibility to early life adversities and cardiovascular disease risk across the lifespan: Implications for future research.

Prev Med 2021 Jul 19:106736. Epub 2021 Jul 19.

Department of Psychology, University of Denver, Denver, CO, United States of America.

Early life adversities (ELA), include experiences such as child maltreatment, household dysfunction, bullying, exposure to crime, discrimination, bias, and victimization, and are recognized as social determinants of cardiovascular disease (CVD). Strong evidence shows exposure to ELA directly impacts cardiometabolic risk in adulthood and emerging evidence suggests there may be continuity in ELA's prediction of cardiometabolic risk over the life course. Extant research has primarily relied on a cumulative risk framework to evaluate the relationship between ELA and CVD. Read More

View Article and Full-Text PDF

The role of psychosocial factors in the decision to enroll in physical education courses at the state college level.

J Am Coll Health 2021 Jul 22:1-8. Epub 2021 Jul 22.

Department of Health Sciences, College of Health Professions and Sciences, University of Central Florida, Orlando, Florida, USA.

Objective: Physical education (PE) courses may provide young adults with opportunities to become active, however, enrollment in college PE courses remains low.

Participants: This study examined psychosocial factors related to PE enrollment in a sample of 177 college students (29.4% completed a PE course). Read More

View Article and Full-Text PDF

Prevalence of hyperventilation in patients with asthma.

J Asthma 2021 Jul 22:1-11. Epub 2021 Jul 22.

Radboud university medical center, Radboud Institute for Health Sciences, Department of Respiratory Diseases, 6525 GA Nijmegen, The Netherlands.

Objective: Asthma is frequently accompanied by dysfunctional breathing of which hyperventilation has been recognized as a subtype. The prevalence of hyperventilation in stable asthma has been scantily studied using blood gas analysis. Hence, a reliable estimate of its prevalence is lacking. Read More

View Article and Full-Text PDF

Exploring the association Between Cardiovascular Health measured with CANHEART model and early cognitive impairment in middle-aged population.

Epidemiol Health 2021 Jul 13:e2021044. Epub 2021 Jul 13.

Yonsei University College of Medicine, Seoul, Korea.

Background: Both cardiovascular health (CVH) and inflammation associated with cognition, and inflammation also associated with cardiovascular health. However, related information in the Korean population is limited. The objective of our study was to confirm the influence of inflammation on the association between CVH and cognition in cross-sectional design. Read More

View Article and Full-Text PDF

The interactions between childhood adversities and recent stress were associated with early-adulthood depression among Chinese undergraduate students.

Depress Anxiety 2021 Jul 22. Epub 2021 Jul 22.

Mental Health Center and Psychiatric Laboratory, the State Key Laboratory of Biotherapy, West China Hospital of Sichuan University, Chengdu, Sichuan, China.

Background: It is widely acknowledged that childhood adversities (CAs) and recent stress are potential risk factors for adult depression. However, the mechanism(s) by which interactions of CAs with recent stress affect adult depression remain unclear.

Aims: To investigate the predictive association of the interaction among CAs and recent stress with early-adult depression. Read More

View Article and Full-Text PDF

Emotional intelligence training as a protective factor for mental health during the COVID-19 pandemic.

Depress Anxiety 2021 Jul 22. Epub 2021 Jul 22.

Department of Psychiatry, University of Arizona, Tucson, Arizona, USA.

Introduction: The COVID-19 pandemic has presented a major challenge to mental health and emotional wellbeing. The present study examined whether training in emotional intelligence (EI) skills, provided before the pandemic, would serve as a protective factor for sustaining mental health during the COVID-19 crisis.

Methods: Data came from a longitudinal study (N = 89) that was initially designed to test the effectiveness of an EI training program versus a non-emotion-focused placebo program. Read More

View Article and Full-Text PDF

Narrative frames as choice over structure of American Indian sexual and reproductive health consequences of historical trauma.

Sociol Health Illn 2021 Jul 22. Epub 2021 Jul 22.

Montana State University, Bozeman, Montana, USA.

Emerging evidence suggests that the historical trauma associated with settler colonialism affects the sexual and reproductive health (SRH) of American Indian (AI) communities today. This article examines how one AI community narratively frames the influence of historical trauma within the context of community-based participatory research (CBPR) and the implications of this framing for health behaviours, internalized oppression, SRH outcomes, and future CBPR interventions. We found that AIs framed the SRH consequences of historical trauma with renderings that favoured personal choice over structural explanations. Read More

View Article and Full-Text PDF

Reproducibility and Validity of Capillary Dried Blood Spot for Diagnosis of Vitamin A Deficiency and Anemia in Children <5 Years Old.

J Nutr 2021 Jul 22. Epub 2021 Jul 22.

Department of Social Nutrition, Nutrition Institute, Rio de Janeiro State University, Rio de Janeiro, Brazil.

Background: Vitamin A deficiency (VAD) and anemia are the most prevalent nutritional deficiency in children globally. The dried blood spot (DBS) method has been used in prevalence studies of VAD and anemia in different age groups. However, it has not yet been validated for children. Read More

View Article and Full-Text PDF

Effects of canagliflozin on human myocardial redox signalling: clinical implications.

Eur Heart J 2021 Jul 19. Epub 2021 Jul 19.

Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, L6 West Wing, John Radcliffe Hospital, Headley Way, Oxford OX3 9DU, UK.

Aims: Recent clinical trials indicate that sodium-glucose cotransporter 2 (SGLT2) inhibitors improve cardiovascular outcomes in heart failure patients, but the underlying mechanisms remain unknown. We explored the direct effects of canagliflozin, an SGLT2 inhibitor with mild SGLT1 inhibitory effects, on myocardial redox signalling in humans.

Methods And Results: Study 1 included 364 patients undergoing cardiac surgery. Read More

View Article and Full-Text PDF

Development of emodepside as a possible adulticidal treatment for human onchocerciasis-The fruit of a successful industrial-academic collaboration.

PLoS Pathog 2021 Jul 22;17(7):e1009682. Epub 2021 Jul 22.

Department of Biomedical Sciences, Iowa State University, Ames, Iowa, United States of America.

Current mass drug administration (MDA) programs for the treatment of human river blindness (onchocerciasis) caused by the filarial worm Onchocerca volvulus rely on ivermectin, an anthelmintic originally developed for animal health. These treatments are primarily directed against migrating microfilariae and also suppress fecundity for several months, but fail to eliminate adult O. volvulus. Read More

View Article and Full-Text PDF

Both high and low pre-infection glucose levels associated with increased risk for severe COVID-19: New insights from a population-based study.

PLoS One 2021 22;16(7):e0254847. Epub 2021 Jul 22.

Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.

Importance: Patients with diabetes are known to be at increased risk for infections including severe coronavirus disease 2019 (COVID-19) but the relationship between COVID-19 severity and specific pre-infection glucose levels is not known.

Objective: To assess the differential effects of pre-infection glucose levels on the risk for severe COVID-19 amongst patients with and without diabetes.

Design: Population based historical cohort study. Read More

View Article and Full-Text PDF