218,297 results match your criteria health problems


Prescription pattern of antimicrobial use in small animal veterinary practice in Cameroon.

Top Companion Anim Med 2021 May 10:100540. Epub 2021 May 10.

College of Technology, University of Bamenda, Bambili, Cameroon. Electronic address:

Retrospective data on antimicrobial use (AMU) within the period ranging from January 2012 to December 2015 was collected to assess the antimicrobial prescription patterns in pets (cats and dogs) treated by 16 veterinary private practitioners in the two main urban cities of Cameroon (Douala and Yaounde). The vet practitioners were interviewed in order to analyze prescribing behavior and factors influencing antimicrobial prescription. Out of a total of 3928 antimicrobial prescriptions, 3673(93. Read More

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Prevalence, predictors and correlates of religious and spiritual struggles in palliative cancer patients.

J Pain Symptom Manage 2021 May 10. Epub 2021 May 10.

Department of Religion, Health and Human Values, Rush University Medical Center, Chicago, Illinois.

Context: Religion and spirituality (r/s) are important resources in coping with cancer. However, there are aspects of r/s, such as religious and spiritual struggles, found to be associated with poorer outcomes. A new measure has been adapted from the Religious and Spiritual Struggles Scale (RSS) to assess r/s struggles: the RSS-14. Read More

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Functional Outcomes, Goals, and Goal Attainment Amongst Chronically Critically Ill Long-Term Acute Care Hospital Patients.

Ann Am Thorac Soc 2021 May 13. Epub 2021 May 13.

University of Pennsylvania Perelman School of Medicine, 14640, Philadelphia, Pennsylvania, United States.

Rationale: Chronically critically ill patients admitted to a long-term acute care hospital (LTACH) setting are a vulnerable population of intensive care unit survivors. Little is known of the goals and functional outcomes achieved by patients after rehabilitation in the LTACH setting.

Objectives: We sought to examine patient goals and functional outcomes, including swallowing function, amongst ICU survivors admitted to an LTACH with a tracheostomy. Read More

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Recent advances in the microbial production of C4 alcohols by metabolically engineered microorganisms.

Biotechnol J 2021 May 13:e2000451. Epub 2021 May 13.

Department of Chemical Engineering and Materials Science, Graduate Program in System Health Science and Engineering, Ewha Womans University, Seoul, 03760, Republic of Korea.

Background: The heavy global dependence on petroleum-based industries has led to serious environmental problems, including climate change and global warming. As a result, there have been calls for a paradigm shift towards the use of biorefineries, which employ natural and engineered microorganisms that can utilize various carbon sources from renewable resources as host strains for the carbon-neutral production of target products.

Purpose And Scope: C4 alcohols are versatile chemicals that can be used directly as biofuels and bulk chemicals and in the production of value-added materials such as plastics, cosmetics, and pharmaceuticals. Read More

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The effectiveness of nicotine replacement therapy in light versus heavier smokers.

Nicotine Tob Res 2021 May 13. Epub 2021 May 13.

University of Toronto, Department of Pharmacology & Toxicology, Toronto, ON.

Purpose: The prevalence of light smoking has increased in North America; however, research on the effectiveness of current treatments in this sub-population of smokers is limited. We compared quit outcomes between light (1-10 cigarettes per day (CPD)) versus heavier smokers (>10 CPD) enrolled in a treatment program at their primary care clinic.

Methods: This secondary analysis analyzed 45,087 participants (light smokers (n=9,861); heavier smokers (n=35,226)) enrolled in a smoking cessation program between April 2016 and March 2020. Read More

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Mesoporous silica coated CeO nanozymes with combined lipid-lowering and antioxidant activity induce long-term improvement of the metabolic profile in obese Zucker rats.

Nanoscale 2021 May 14;13(18):8452-8466. Epub 2021 Apr 14.

Service of Biochemistry and Molecular Genetics, Hospital Clinic Universitari, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Carrer de Villarroel, 170, 08036 Barcelona, Spain.

Obesity is one of the most important public health problems that is associated with an array of metabolic disorders linked to cardiovascular disease, stroke, type 2 diabetes, and cancer. A sustained therapeutic approach to stop the escalating prevalence of obesity and its associated metabolic comorbidities remains elusive. Herein, we developed a novel nanocomposite based on mesoporous silica coated cerium oxide (CeO) nanozymes that reduce the circulating levels of fatty acids and remarkably improve the metabolic phenotype in a model of obese Zucker rats five weeks after its administration. Read More

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Men's perception and understanding of male-factor infertility in the UK.

Br J Nurs 2021 May;30(9):S8-S16

Consultant Urologist, Newcastle Fertility Centre, Newcastle-upon-Tyne Hospitals NHS Foundation Trust, Newcastle-upon-Tyne.

Male-factor infertility is a common but stigmatised issue, and men often do not receive the emotional support and the information they need. This study sought to understand awareness of male fertility issues compared to female fertility among the UK general male public, and also what were perceived as being the optimum methods for providing support for affected men, emotionally and through information. Men feel that male infertility is not discussed by the public as much as female infertility. Read More

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Parent ethnic-racial socialization during childhood protects against increases in bedtime sleep problems in Black adolescents.

Am J Orthopsychiatry 2021 ;91(2):236-245

School of Social Work, University of Washington.

Racial disparities in sleep have been reported with Black adolescents showing the least amount of sleep relative to other youth. Yet, few within-group studies have examined factors that protect Black adolescents from sleep problems. To address this gap, we tested whether parent ethnic-racial socialization (i. Read More

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January 2021

The longitudinal associations between attitudes to aging and attachment insecurities among combat veterans.

Am J Orthopsychiatry 2021 ;91(2):162-170

3 I-Core Research Center for Mass Trauma, Bob Shapell School of Social Work, Tel Aviv University.

For combat veterans, the trauma of war can have lasting effects, that may later extend to attitudes toward one's own aging (ATOA). The present study sought to examine whether attachment insecurities may help to predict ATOA in later life, while also exploring the moderating role of combat exposure concerning the effects of attachment insecurities on subsequent ATOA. A cohort of 171 veterans of the Israeli 1973 Yom Kippur War (mean age = 68. Read More

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January 2021

The prefrontal cortex in a pandemic: Restoring functions with system-, family-, and individual-focused interventions.

Am Psychol 2021 May 13. Epub 2021 May 13.

Child Study Center.

The COVID-19 pandemic is an unanticipated and uncontrollable chronic stressor that is detrimental to the mental and behavioral health of children and families, particularly those from disadvantaged and marginalized backgrounds. Chronic stress impairs a myriad of prefrontal cortical functions, important for coping with the COVID-19 pandemic, and has consequences on dyadic parent-child functioning. Informed by neuroscience and clinical evidence, sensitive parenting is a vital avenue of intervention that buffers against the toxic effects of COVID-19 on parent-child mental health. Read More

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Care for Breast Cancer Survivors.

Adv Exp Med Biol 2021 ;1187:511-524

Seoul National University Hospital, Seoul, South Korea.

The number of cancer survivors is increasing globally. More than 15.5 million Americans in 2016 and 1. Read More

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January 2021

A Worksite Self-management Program for Workers with Chronic Health Conditions Improves Worker Engagement and Retention, but not Workplace Function.

J Occup Rehabil 2021 May 13. Epub 2021 May 13.

University of South-Eastern Norway, Raveien 215, 3184, Borre, Norway.

Purpose An increasing number of workers in the US have chronic health conditions that limit their ability to work, and few worksite interventions have been tested to improve worker coping and problem solving at work. The purpose of this study was to evaluate a worksite-based health self-management program designed to improve workplace function among workers with chronic health conditions. Methods We conducted a randomized, controlled trial of a worksite self-management program ("Manage at Work") (clinicaltrials. Read More

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Triple Challenge: How Medical Students May Solve 3 Long-Standing Problems Bedeviling Health Systems and Medical Education.

Acad Med 2021 May 11. Epub 2021 May 11.

V.S. Elliott is a technical writer, Medical Education Outcomes, American Medical Association, Chicago, Illinois. J. Jackson is a resident, Boston Children's Hospital and Boston Medical Center. S.A. Santen is senior associate dean and professor of emergency medicine, Virginia Commonwealth University School of Medicine, Richmond, Virginia, and consultant, American Medical Association, Chicago, Illinois; ORCID: http://orcid.org/0000-0002-8327-8002. J. Richardson is director of research and evaluation, Medical Education Outcomes, American Medical Association, Chicago, Illinois. K. Heckman is director of product development, Medical Education Outcomes, American Medical Association, Chicago, Illinois. M.M. Hammoud is professor of obstetrics & gynecology and learning health sciences, Michigan Medicine, Ann Arbor, Michigan, and consultant, American Medical Association, Chicago, Illinois.

Medical education and the health system must address challenges that, despite significant effort, seem unsolvable. Health systems science (HSS)-the fundamental understanding of how care is delivered, how health professionals work together to deliver that care, and how the health system can improve patient care and health care delivery-is increasingly being recognized as a potential source of solutions to these challenges. In this article, the authors review the 43 abstracts submitted to the American Medical Association Accelerating Change in Medical Education 2018 Health Systems Science Student Impact Competition that aligned with the goals of HSS. Read More

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Flavonoids as potential anti-platelet aggregation agents: from biochemistry to health promoting abilities.

Crit Rev Food Sci Nutr 2021 May 13:1-14. Epub 2021 May 13.

Department of Clinical Pharmacy, University of Medicine and Pharmacy of Craiova, Craiova, Romania.

Cardiovascular ailments are the number one cause of mortalities throughout the globe with 17.9 million deaths per year. Platelet activation and aggregation play a crucial role in the pathogenesis of arterial diseases, including acute coronary syndrome, acute myocardial infarction, cerebrovascular transient ischemia, unstable angina, among others. Read More

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Prenatal nicotine exposure was associated with long-term impact on the cardiovascular system and regulation-review.

Acta Paediatr 2021 May 13. Epub 2021 May 13.

Pediatric Cardiology Unit, Karolinska University Hospital, Department of Women´s and Child´s Health, Karolinska Institute, Karolinska, Sweden.

Aim: The aim of this structured review was to discuss knowledge of nicotine use during pregnancy and long-term effects on children's cardiovascular function.

Methods: PubMed and MEDLINE were searched for original papers that covered various forms of nicotine exposure during pregnancy and this identified 314 papers published in English from inception of the databases to 1 March 2021. The research focus was prenatal exposure that had long-term effects on the cardiovascular system. Read More

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Negative interpretations of ambiguous 'psychosis-like' and 'anxiety-like' experiences in recovery from psychosis or anxiety.

Br J Clin Psychol 2021 May 13. Epub 2021 May 13.

Department of Experimental Psychology, The Oxford Centre for Psychological Health, The Oxford Institute of Clinical Psychology, University of Oxford, Salisbury, UK.

Objectives: Fear of relapse (FOR) after experiencing psychosis has been found to predict actual relapse; however, potential mechanisms underlying this relationship have not been investigated. Negative appraisals of 'prodromal symptoms' are believed to play an important role in both psychosis and mental health anxiety (MHA). This study aimed to explore whether people in recovery from psychosis or anxiety disorders show an enduring tendency to negatively interpret ambiguous experiences both related and less related to their previous mental health difficulty relative to controls. Read More

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Problems associated with antiviral drugs and vaccines development for COVID-19: approach to intervention using expression vectors via GPI anchor.

Authors:
Khue Vu Nguyen

Nucleosides Nucleotides Nucleic Acids 2021 May 13:1-32. Epub 2021 May 13.

Department of Medicine, Biochemical Genetics and Metabolism, The Mitochondrial and Metabolic Disease Center, School of Medicine, University of California, San Diego, San Diego, CA, USA.

The outbreak of a novel coronavirus responsible for the severe acquired respiratory syndrome: SARS-CoV-2, also known as coronavirus disease 2019: COVID-19, represents a pandemic threat that has been declared a public health emergency of international concern. The CoV spike (S) glycoprotein is a key target for diagnostic, development of antibodies, entry inhibitors, and vaccines. COVID-19 also recognizes angiotensin-converting enzyme 2 (ACE2) as its host receptor binding to viral S protein. Read More

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Motives for gambling, cognitive distortions, and irresponsible gambling: Proposal for an explanatory model of gambling addiction in university students.

J Addict Dis 2021 May 13:1-10. Epub 2021 May 13.

Evolutive Psychology Department, Universitat de València, Valencia, Spain.

There are many factors that appear to be directly related to the development of gambling addiction problems, and it is important to understand these relationships from a clinical perspective in order to develop prevention and intervention programs. This research seeks to analyze the relationships these problems have with gambling motives, cognitive distortions and irresponsible gambling behavior, and proposes an explanatory model of gambling addiction. The sample was made up of 258 adults residing in the province of Valencia (59. Read More

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Measurement of neurodevelopmental effects of prenatal alcohol exposure in Ukrainian preschool children.

Child Neuropsychol 2021 May 13:1-16. Epub 2021 May 13.

Collaborative Initiative for Fetal Alcohol Spectrum Disorders.

Effects of prenatal alcohol exposure (PAE) are rarely measured in preschool children due to relative insensitivity of assessment methods at this age. To examine the potential of a nonverbal battery in early identification of cognitive problems in alcohol-exposed children, 291 prospectively identified Ukrainian children were evaluated using a test battery focusing on early executive functioning (EF) and visuospatial skills, areas of cognitive development particularly sensitive to PAE in older children. Tests included the Differential Ability Scales, 2 Edition (DAS-2) and several NEPSY/NEPSY-II subtests, standardized in the United States. Read More

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[Thoughts on post-marketing evaluation of classical Chinese patent medicines based on clinical value].

Zhongguo Zhong Yao Za Zhi 2021 Apr;46(8):1988-1993

Xiyuan Hospital, Chinese Academy of Chinese Medical Sciences Beijing 100091, China.

Classical Chinese patent medicines(CPMs) are a kind of modern preparation developed from the experience of compatibility and application about ancient prescriptions. Its rich history of human use and reliable clinical efficacy imply the unique theoretical essence and precious value of traditional Chinese medicine(TCM). With the development of evidence-based medicine and the improvement of medical policy, it is particularly urgent to evaluate the clinical values of post-marketing classical CPMs. Read More

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Element concentration, daily intake of elements, and health risk indices of wild mushrooms collected from Belgrad Forest and Ilgaz Mountain National Park (Turkey).

Environ Sci Pollut Res Int 2021 May 13. Epub 2021 May 13.

Faculty of Science and Literature, Department of Molecular Biology and Genetics, Kilis 7 Aralik University, TR-79000, Kilis, Turkey.

The aim of this study was to determine the element content of wild edible and inedible mushroom species (Agaricus campestris, Armillaria ostoyae, Boletus reticulatus, Bondarzewia mesenterica, Bovistella utriformis, Cantharellus cibarius, Marasmius oreades, Megacollybia platyphylla, Meripilus giganteus, Neoboletus erythropus, Panellus stipticus, Phaeotremella foliacea, Pleurotus ostreatus, Podoscypha multizonata, Russula aurea, R. chloroides, R. virescens, T. Read More

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Averting a public health crisis in England's coastal communities: a call for public health research and policy.

J Public Health (Oxf) 2021 May 13. Epub 2021 May 13.

Plymouth Institute of Health and Care Research (PIHR), University of Plymouth, Drake Circus, Plymouth PL4 8AA, UK.

Coastal communities have received little attention in the public health literature, perhaps because our mental maps tend to associate socio-economic deprivation and health inequalities with inner cities. Mapping a range of key health indicators at small area level, this paper reveals a distinct core-periphery pattern in disease prevalence, with coastal communities experiencing a high burden of ill health across almost all conditions included in the Quality and Outcomes Framework dataset. Other sources suggest poor outcomes for children and young people living in coastal areas. Read More

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The contribution of hypochondria resulting from Corona virus on the occupational productivity loss through increased job stress and decreased resilience in the central workshop of an oil refinery: A path analysis.

Heliyon 2021 Apr 18;7(4):e06808. Epub 2021 Apr 18.

Department of Occupational Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

The prevalence of contagious viral-infectious diseases such as COVID19 cause the economic problems in addition to harmful effect on the people health. The present study was aimed to determine the contribution of hypochondria resulting from Corona virus on the occupational productivity loss through increased job stress and decreased resilience in the central workshop of an oil refinery. This cross-sectional study was conducted on 275 subjects in the spring of 2020 in one of the oil and gas industries in southern Iran. Read More

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Impaired Touchscreen Skills in Parkinson's Disease and Effects of Medication.

Mov Disord Clin Pract 2021 May 12;8(4):546-554. Epub 2021 Mar 12.

KU Leuven, Department of Rehabilitation Sciences Research Group for Neurorehabilitation (eNRGy) Leuven Belgium.

Background: Deficits in fine motor skills may impair device manipulation including touchscreens in people with Parkinson's disease (PD).

Objectives: To investigate the impact of PD and anti-parkinsonian medication on the ability to use touchscreens.

Methods: Twelve PD patients (H&Y II-III), OFF and ON medication, and 12 healthy controls (HC) performed tapping, single and multi-direction sliding tasks on a touchscreen and a mobile phone task (MPT). Read More

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A Public Mental Health Study Among Iraqi Refugees in Sweden: Social Determinants, Resilience, Gender, and Cultural Context.

Front Sociol 2021 26;6:551105. Epub 2021 Apr 26.

Department of Learning, Informatics, Management and Ethics, National Centre for Suicide Research and Prevention of Mental Ill-Health, Karolinska Institutet, Stockholm, Sweden.

This public mental health study highlights the interactions among social determinants and resilience on mental health, PTSD and acculturation among Iraqi refugees in Sweden 2012-2013. The study aims to understand participants' health, resilience and acculturation, paying specific attention to gender differences. The study, using a convenience sampling survey design ( = 4010, 53. Read More

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Biogenic Silver Nanoparticles as a Strategy in the Fight Against Multi-Resistant Isolated From Dairy Calves.

Front Bioeng Biotechnol 2021 26;9:644014. Epub 2021 Apr 26.

Área de Microbiología, Departamento de Biociencias, Facultad de Química, Universidad de la República, Montevideo, Uruguay.

Infectious diseases are one of the most important health problems worldwide, one of the main causes being the development of multi-resistant microorganisms. Likewise, the zoonotic potential of some pathogens and their ability to transfer resistance mechanisms, reduce the therapeutic options in both humans and animals. is an important pathogen that affects a wide range of animal species and humans, being Typhimurium one of the most frequent serotypes affecting cattle, causing enteritis, diarrhea, and septicemia. Read More

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Feeling Valued and Adding Value: A Participatory Action Research Project on Co-creating Practices of Social Inclusion in Kindergartens and Communities.

Front Public Health 2021 26;9:604796. Epub 2021 Apr 26.

Department of Public Health and Nursing, Norwegian University of Science and Technology, Trondheim, Norway.

Contemporary public health problems connect to the social determinants of health, with a growing recognition of social inclusion as imperative to sustainable development. In this quest for social inclusion, early childhood and families are of particular interest. Although co-creation is suggested as viable path to support well-being, less is known how social inclusion might be co-created in practice. Read More

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Incidence of postoperative complications and non- periprosthetic fractures after total hip arthroplasty: A more than 10-year follow-up retrospective cohort study.

Phys Ther Res 2021 13;24(1):77-83. Epub 2020 Nov 13.

Department of Orthopaedic Surgery, Shonan Kamakura Joint Reconstruction Center, Japan.

Objective: Postoperative complications and non-periprosthetic fractures (NPPFs), which was defined as a fracture existing non- periprosthetic implant, after total hip arthroplasty (THA) have a negative effect on the patients' ability to perform activities of daily living. Thus, investigating these incidences of patients after THA will be valuable as it lead to a more strategic physical therapy interventions and advanced research to prevent these problems. The purpose of this study was to investigate the incidence of postoperative complications related to implants and NPPFs in patients after THA, a more than 10-year follow-up. Read More

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November 2020

Exercise training in dialysis patients: impact on cardiovascular and skeletal muscle health.

Clin Kidney J 2021 Apr 11;14(Suppl 2):ii25-ii33. Epub 2021 Jan 11.

Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

Dialysis patients show a high rate of reduced functional capacity, morbidity and mortality. Cardiovascular disorders, muscle atrophy and malnutrition play an essential role among the aetiological factors. Sedentary lifestyle characterizes them and contributes to the aggravation of the disorders. Read More

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Is COVID-19 Keeping us Up at Night? Stress, Anxiety, and Sleep Among Adult Twins.

Front Neurosci 2021 26;15:665777. Epub 2021 Apr 26.

Department of Nutrition and Exercise Physiology, Washington State University Health Sciences Spokane, Spokane, WA, United States.

In response to the COVID-19 pandemic, a variety of social distancing measures to mitigate the virus outbreak have been implemented. These measures may have unintended consequences on individuals' well-being, such as increased stress, anxiety, and sleep disruptions. We investigated the extent to which individuals' mental health status is associated with perceived changes in sleep amount and sleep quality among a sample of adult twin pairs ( = 909 pairs; 77% MZ, 23% DZ), less than a month after the outbreak was declared a pandemic by the World Health Organization. Read More

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