205,123 results match your criteria health nutrition

The Relationship of Lifestyle Factors with the Prevalence of Major Depressive Disorder by Ecological Factors.

Psychiatry Investig 2021 Apr 25;18(4):340-347. Epub 2021 Apr 25.

Department of Preventive Medicine, Kangwon National University School of Medicine, Chuncheon, Republic of Korea.

Objective: The association between ecological/lifestyle factors and major depressive disorder (MDD) have been provided but was inconsistent as characteristics of population including race, gender, etc.

Methods: Data were extracted from the Korean National Health and Nutrition Examination Survey and consisted of 35,839 adults including 1,537 with MDD. Ecological factors included age, sex, married status, education, family income, residence, occupation, BMI, self-recognition stress, and history of non-communicable disease. Read More

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The effect of on obesity related metabolic disorders: a systematic review of randomized controlled trials.

J Complement Integr Med 2021 May 5. Epub 2021 May 5.

Nutrition Research Center, Department of Community Nutrition, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.

Objectives: (CV) as a unicellular algae is a dietary supplement with beneficial nutritious content, used for decades in some countries. Positive effects for CV supplementation on metabolic parameters has been established in animal and human studies. However there is a gap for this results summary for a definite conclusion announce. Read More

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Use of lemongrass essential oil as a feed additive in quail's nutrition: its effect on growth, carcass, blood biochemistry, antioxidant and immunological indices, digestive enzymes and intestinal microbiota.

Poult Sci 2021 Mar 26;100(6):101172. Epub 2021 Mar 26.

Poultry Department, Faculty of Agriculture, Zagazig University, Zagazig 44511, Egypt.

The present study was designed to assess the impact of dietary supplementation of lemongrass essential oil (LGEO) on growth performance, carcass traits, liver and kidney function, immunity, antioxidant indices and caecal microbiota of growing quail. A total of 200 Japanese quails at 1-week-old were haphazardly allotted to 5 groups of 40 chicks in five replicates (8 per replicate). The first group was the control group, while LGEO was added at levels of 150, 300, 450, and 600 mg/kg diet in the 2nd, 3rd, 4th and 5th groups, respectively. Read More

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Cecal microbiota contribute to the development of woody breast myopathy.

Poult Sci 2021 Mar 13;100(6):101124. Epub 2021 Mar 13.

Department of Food Science, Nutrition, and Health Promotion, Mississippi State University, Mississippi State, MS 39762, USA. Electronic address:

The objective of this study was to characterize the bacterial diversity of cecal microbiota in broilers related to breast phenotype, diet, and genetic strain. Broilers from 2 genetic strains (120 birds/strain) were fed a control diet (15 birds/pen) and an amino acid reduced diet (15 birds/pen, digestible lysine, total sulfur amino acids, and threonine reduced by 20% compared to the control diet). At 8 wk of age, 4 male broilers with normal breast (NB, 1 chick per pen) and 4 male broilers with woody breast (WB, 1 chick per pen) were selected for each treatment (strain × diet). Read More

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Identification of chemicals of emerging concern in urine of Flemish adolescents using a new suspect screening workflow for LC-QTOF-MS.

Chemosphere 2021 Apr 27;280:130683. Epub 2021 Apr 27.

Toxicological Center, University of Antwerp, Universiteitsplein 1, 2610, Wilrijk, Belgium. Electronic address:

An essential step in human biomonitoring or molecular epidemiology programs is to estimate human exposure to environmental chemicals. Despite significant progress in the capabilities of analytical methods, the number of pollutants and their metabolites keeps increasing continuously. Some of these relatively unknown chemicals of emerging concern (CECs) may pose significant health risks to humans and biota, but remain virtually undetected in traditional HBM-studies. Read More

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Midlobular zone 2 hepatocytes: A gatekeeper of liver homeostasis.

Cell Metab 2021 May;33(5):855-856

Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan; Toranomon Hospital, Tokyo, Japan. Electronic address:

The liver consists of different zones that vary in function depending on their lobular localization. It remained unclear which zone serves as a source of repopulating/regenerating hepatocytes; however, experiments by Wei et al. (2021) in 11 CreER knockin murine strains revealed a vital role for zone 2 hepatocytes in liver homeostasis. Read More

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Axon-enriched lincRNA ALAE is required for axon elongation via regulation of local mRNA translation.

Cell Rep 2021 May;35(5):109053

State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, CAS Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, China; Shanghai Research Center for Brian Science and Brain-Inspired Intelligence, Shanghai, China. Electronic address:

Long intergenic noncoding RNAs (lincRNAs) are critical regulators involved in diverse biological processes. However, the roles and related mechanisms of lincRNAs in axon development are largely unknown. Here we report an axon-enriched lincRNA regulating axon elongation, referred to as ALAE. Read More

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Ustekinumab is more effective than azathioprine to prevent endoscopic postoperative recurrence in Crohn's disease.

United European Gastroenterol J 2021 May 5. Epub 2021 May 5.

Department of Gastroenterology, University Hospital of Besançon, University Bourgogne FrancheComté, Besançon, France.

Background: Preventing postoperative recurrence (POR) is a major concern in Crohn's disease (CD). While azathioprine is an option, no data is available on ustekinumab efficacy in this situation.

Aims: We compared the effectiveness of ustekinumab versus azathioprine in preventing endoscopic POR in CD. Read More

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Basal protein synthesis rates differ between vastus lateralis and rectus abdominis muscle.

J Cachexia Sarcopenia Muscle 2021 May 5. Epub 2021 May 5.

Department of Human Biology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht, The Netherlands.

Background: In vivo muscle protein synthesis rates are typically assessed by measuring the incorporation rate of stable isotope labelled amino acids in skeletal muscle tissue collected from vastus lateralis muscle. It remains to be established whether muscle protein synthesis rates in the vastus lateralis are representative of muscle protein synthesis rates of other muscle groups. We hypothesized that post-absorptive muscle protein synthesis rates differ between vastus lateralis and rectus abdominis, pectoralis major, or temporalis muscle in vivo in humans. Read More

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Exposure to obesogenic endocrine disrupting chemicals and obesity among youth of Latino or Hispanic origin in the United States and Latin America: A lifecourse perspective.

Obes Rev 2021 May 5:e13245. Epub 2021 May 5.

Center for Nutrition and Health Research, National Institute of Public Health, Mexico City, Mexico.

Following a 2019 workshop led by the Center for Global Health Studies at the Fogarty International Center on the topic of childhood obesity prevention and research synergies transpiring from cross-border collaborations, we convened a group of experts in the United States and Latin America to conduct a narrative review of the epidemiological literature on the role of obesogenic endocrine disrupting chemicals (EDCs) in the etiology of childhood obesity among Latino youth in the United States and Latin America. In addition to summarizing and synthesizing results from research on this topic published within the last decade, we place the findings within a lifecourse biobehavioral framework to aid in identification of unique exposure-outcome relationships driven by both biological and behavioral research, identify inconsistencies and deficiencies in current literature, and discuss the role of policy regulations, all with the goal of identifying viable avenues for prevention of early life obesity in Latino/Hispanic populations. Read More

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Implementation of childhood obesity prevention and control policies in the United States and Latin America: Lessons for cross-border research and practice.

Obes Rev 2021 May 5:e13247. Epub 2021 May 5.

Fogarty International Center, National Institutes of Health, Bethesda, Maryland, USA.

Progress has been made in the development and widespread implementation of effective interventions to address childhood obesity, yet important challenges remain. To understand how the United States and Latin American countries achieved success in implementing obesity policies and programs (PAPs) and identify improvement opportunities using implementation science principles. We identified three comparative case studies: (1) front-of-food package labeling (Mexico and Chile); (2) Open Streets/play streets (Colombia and the United States); and (3) the Baby-Friendly Hospital Initiative (Brazil and the United States). Read More

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The social environment and childhood obesity: Implications for research and practice in the United States and countries in Latin America.

Obes Rev 2021 May 5:e13246. Epub 2021 May 5.

Department of Family Medicine and Community Health, Medical School, University of Minnesota, Minneapolis, Minnesota, USA.

The environments of children influence their risk for childhood obesity through, among other factors, a child's weight-related behaviors (i.e., diet and physical activity). Read More

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Maternal Selenium Status has Crucial Role on Clinical Outcomes Of Pregnant Women With COVID-19 Infection.

J Med Virol 2021 May 5. Epub 2021 May 5.

University of Health Sciences, Department of Obstetrics and Gynecology, Ministry of Health, Ankara City Hospital, Ankara, Turkey.

Aim: Adequate maternal selenium level is essential for immune response and healthy pregnancy. This study aimed to enlighten selenium status of pregnant women with COVID-19 and the effects of potential deficiency in serum selenium levels.

Methods: Totally 141 pregnant women, 71 of them was COVID-19 patients, in different trimesters were included in the study. Read More

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Perspective: Defining Carbohydrate Quality for Human Health and Environmental Sustainability.

Adv Nutr 2021 May 5. Epub 2021 May 5.

Department of Food Science and Nutrition, University of Minnesota, St. Paul, MN, USA.

Plant foods are universally promoted for their links to improved human health, yet carbohydrate-containing foods are often maligned based on isolated, reductionist methods that fail to assess carbohydrate foods as a matrix of nutrients and food components. Currently accepted positive carbohydrate quality indices include plant food, whole-grain content, and dietary fiber, while negative health outcomes are linked to high intakes of added sugar and high glycemic index. More recently, negative health aspects have been linked to ultra-processed foods, which are often high in carbohydrates. Read More

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A Systematic Review of Dietary Influences on Fecal Microbiota Composition and Function among Healthy Humans 1-20 Years of Age.

Adv Nutr 2021 May 5. Epub 2021 May 5.

Division of Nutritional Sciences, University of Illinois at Urbana-Champaign, Urbana, IL, USA.

Diet is a key modulator of fecal microbiota composition and function. However, the influence of diet on the microbiota from toddlerhood to adolescence and young adulthood is less well studied than for infancy and adulthood. We aimed to complete a qualitative systematic review of the impacts of diet on the fecal microbiota of healthy humans 1-20 y of age. Read More

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Association between Sarcopenic Obesity and Nonalcoholic Fatty Liver Disease and Fibrosis detected by Fibroscan.

J Gastrointestin Liver Dis 2021 May 3. Epub 2021 May 3.

Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA, USA.

Background And Aims: Nonalcoholic fatty liver disease (NAFLD) and sarcopenic obesity share several pathophysiologic backgrounds. No prior studies have determined a plausible association between sarcopenic obesity and NAFLD and NAFLD-associated fibrosis. We aim to investigate the association between sarcopenic obesity and NAFLD, and NAFLD-associated fibrosis detected by transient elastography. Read More

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Romanian Guidelines for Nonpharmacological Therapy of IBS.

J Gastrointestin Liver Dis 2021 May 3. Epub 2021 May 3.

Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca; 2nd Department of Internal Medicine, Cluj-Napoca, Romania.

Background And Aims: The nonpharmacological therapy in irritable bowel syndrome (IBS) is expanding rapidly. Practitioners and medical educators need to be aware of progress and changes in knowledge of this topic. The Romanian Society of Neurogastroenterology aimed to create guidelines based on best evidence on the use of nonpharmacological therapy in IBS. Read More

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A cluster-randomised controlled trial of the LifeLab education intervention to improve health literacy in adolescents.

PLoS One 2021 5;16(5):e0250545. Epub 2021 May 5.

NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom.

Adolescence offers a window of opportunity during which improvements in health behaviours could benefit long-term health, and enable preparation for parenthood-albeit a long way off, passing on good health prospects to future children. This study was carried out to evaluate whether an educational intervention, which engages adolescents in science, can improve their health literacy and behaviours. A cluster-randomised controlled trial of 38 secondary schools in England, UK was conducted. Read More

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Nutritional markers of undiagnosed type 2 diabetes in adults: Findings of a machine learning analysis with external validation and benchmarking.

PLoS One 2021 5;16(5):e0250832. Epub 2021 May 5.

Monash Centre for Health Research and Implementation, School of Public Health and Preventive Medicine, Faculty of Medicine, Nursing, and Health Sciences, Monash University, Clayton, Australia.

Objectives: Using a nationally-representative, cross-sectional cohort, we examined nutritional markers of undiagnosed type 2 diabetes in adults via machine learning.

Methods: A total of 16429 men and non-pregnant women ≥ 20 years of age were analysed from five consecutive cycles of the National Health and Nutrition Examination Survey. Cohorts from years 2013-2016 (n = 6673) was used for external validation. Read More

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Nutritional markers and proteome in patients undergoing treatment for pulmonary tuberculosis differ by geographic region.

PLoS One 2021 5;16(5):e0250586. Epub 2021 May 5.

Division of Pulmonary and Critical Care Medicine and UCSF Center for Tuberculosis, University of California San Francisco, San Francisco, California, United States of America.

Introduction: Contemporary phase 2 TB disease treatment clinical trials have found that microbiologic treatment responses differ between African versus non-African regions, the reasons for which remain unclear. Understanding host and disease phenotypes that may vary by region is important for optimizing curative treatments.

Methods: We characterized clinical features and the serum proteome of phase 2 TB clinical trial participants undergoing treatment for smear positive, culture-confirmed TB, comparing host serum protein expression in clinical trial participants enrolled in African and Non-African regions. Read More

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Genomic surveillance of antimicrobial resistance shows cattle and poultry are a moderate source of multi-drug resistant non-typhoidal Salmonella in Mexico.

PLoS One 2021 5;16(5):e0243681. Epub 2021 May 5.

Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México, Ciudad de México, México.

Multi-drug resistant (MDR) non-typhoidal Salmonella (NTS) is a public health concern globally. This study reports the phenotypic and genotypic antimicrobial resistance (AMR) profiles of NTS isolates from bovine lymph nodes (n = 48) and ground beef (n = 29). Furthermore, we compared genotypic AMR data of our isolates with those of publicly available NTS genomes from Mexico (n = 2400). Read More

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The neural correlates of delay discounting in obesity and binge eating disorder.

J Behav Addict 2021 Apr 26. Epub 2021 Apr 26.

1Department of Psychiatry, Bellvitge University Hospital-IDIBELL, C/Feixa Llarga s/n, 08907, Barcelona, Spain.

Background And Aims: Increased delay discounting is associated with obesity and binge eating disorder (BED). Although BED and obesity frequently co-occur, the neural mechanisms underlying delay discounting in these conditions remain poorly understood.

Methods: Thirtyfive women with obesity, including 10 participants with obesity and BED and 31 controls completed a monetary delay discounting task during functional magnetic resonance imaging. Read More

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Estimating the COVID-19 spread through real-time population mobility patterns: surveillance in Low- and Middle- income countries.

J Med Internet Res 2021 Feb 21. Epub 2021 Feb 21.

School of Nursing, Hong Kong Ppolytechnic University, Hong Kong, HK.

Background: On January 30, 2020, the World Health Organization (WHO) declared the current novel coronavirus disease 2019 (COVID-19) as a public health emergency of international concern and later characterized it as a pandemic. Since then, the virus has also rapidly spread among Latin American, Caribbean and African countries. The first aim of this study was to identify new emerging COVID-19 clusters over time and in space in Latin American, Caribbean, and African regions [mostly low- and middle-income countries (LMICs)], using a prospective space-time scan measurement approach. Read More

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February 2021

Human-associated scarcity of hosts for tsetse flies (Diptera: Glossinidae) is related to an increase in prevalence of trypanosome infection in flies in north-eastern Zambia.

Trop Anim Health Prod 2021 May 5;53(2):305. Epub 2021 May 5.

School of Life Sciences, University of KwaZulu-Natal, Durban, South Africa.

Occurrence of nutritional stress (due to depletion of fat reserves) in tsetse flies, associated with inadequate levels of access to blood meals, enhances susceptibility of the flies to trypanosome infection. Thus, in a tsetse-infested area, a spatial gradient of reducing tsetse habitat quality is potentially a gradient of increasing prospects for occurrence of stress in tsetse flies. This study investigated prevalence of trypanosome infection in Glossina morsitans morsitans and G. Read More

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An exploratory analysis to identify behavior change techniques of implementation interventions associated with the implementation of healthy canteen policies.

Transl Behav Med 2021 May 5. Epub 2021 May 5.

Hunter New England Local Health District, Population Health, New Lambton, NSW, Australia.

Empirical studies to disentangle the effects of multicomponent implementation interventions are needed to inform the development of future interventions. This study aims to examine which behavior change techniques (BCTs) primarily targeting canteen manager are associated with school's healthy canteen policy implementation. This is a secondary data analysis from three randomized controlled trials assessing the impact of a "high," "medium," and "low" intensity intervention primarily targeting canteen managers on school's implementation of a healthy canteen policy. Read More

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RPS Brazilian Birth Cohorts Consortium (Ribeirão Preto, Pelotas and São Luís): history, objectives and methods.

Cad Saude Publica 2021 30;37(4):e00093320. Epub 2021 Apr 30.

Universidade Federal do Maranhão, São Luís, Brasil.

This paper describes the history, objectives and methods used by the nine Brazilian cohorts of the RPS Brazilian Birth Cohorts Consortium (Ribeirão Preto, Pelotas and São Luís) Common thematic axes are identified and the objectives, baseline periods, follow-up stages and representativity of the population studied are presented. The Consortium includes three birth cohorts from Ribeirão Preto, São Paulo State (1978/1979, 1994 and 2010), four from Pelotas, Rio Grande do Sul State (1982, 1993, 2004 and 2015), and two from São Luís, Maranhão State (1997 and 2010). The cohorts cover three regions of Brazil, from three distinct states, with marked socioeconomic, cultural and infrastructure differences. Read More

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Mediterranean Diet, Brain and Muscle: Olive Polyphenols and Resveratrol Protection in Neurodegenerative and Neuromuscular Disorders.

Curr Med Chem 2021 May 3. Epub 2021 May 3.

Institute of Biochemistry and Cell Biology, Section of Neurobiology, (IBBC-CNR), Rome. Italy.

The Mediterranean diet is worldwide recognized as a good prototype of nutrition due to the conspicuous intake of olive oil, nuts, red wine, legumes, fruit, and vegetables, all fundamental elements rich in antioxidant substances and polyphenols. Polyphenols are a wide range of phytochemicals and/or synthetic chemical compounds with proven beneficial properties for human health. In the present review, we critically summarize the well-characterized antioxidant and anti-inflammatory properties of polyphenols contained in the olives and extra virgin olive oil and of resveratrol, a non-flavonoid phenolic compound. Read More

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Hamstring and gluteal activation during high-speed overground running: Impact of prior strain injury.

J Sports Sci 2021 May 5:1-7. Epub 2021 May 5.

School of Exercise and Nutrition Science, Faculty of Health, Queensland University of Technology, Brisbane, Australia.

This study examined the spatial patterns of hamstring and gluteal muscle activation during high-speed overground running in limbs with and without aprior hamstring strain injury. Ten active males with arecent (<18 month) unilateral biceps femoris long head (BFLH) strain injury underwent functional magnetic resonance imaging before and immediately after arepeat-sprint running protocol. Transverse relaxation (T2) time, an index of muscle activation, of the BFLH and short head (BFSH), semitendinosus (ST), semimembranosus (SM), gluteus maximus (GMAX) and medius (GMED) was assessed pre-post exercise. Read More

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Lessons learned from 25 Years of Research into Long term Consequences of Prenatal Exposure to the Dutch famine 1944-45: The Dutch famine Birth Cohort.

Int J Environ Health Res 2021 May 5:1-15. Epub 2021 May 5.

Department of Epidemiology and Data Science, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.

This paper describes the findings of a historical cohort study of men and women born around the time of the Dutch famine 1944-45. It provided the first direct evidence in humans of the lasting consequences of prenatal undernutrition. The effects of undernutrition depended on its timing during gestation, and the organs and tissues undergoing periods of rapid development at that time. Read More

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Effective behavior change techniques to promote physical activity in adults with overweight or obesity: A systematic review and meta-analysis.

Obes Rev 2021 May 5:e13258. Epub 2021 May 5.

Assistance Publique-Hôpitaux de Paris (AP-HP), Pitié-Salpêtrière Hospital, Department of Nutrition, Institute of Cardiometabolism and Nutrition, Sorbonne University, Paris, France.

Multicomponent behavior change interventions are typically used in weight management, but results are largely heterogeneous and modest. Determining which techniques (behavior change technique [BCTs]) are more effective in changing behavior is thus required. This study aimed to identify the most effective BCTs for increasing physical activity (PA) in digital and face-to-face behavior change interventions in adults with overweight/obesity. Read More

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