1,686,883 results match your criteria health economic

Temperament and Academic Achievement in Children: A Meta-Analysis.

Eur J Investig Health Psychol Educ 2021 Jul 12;11(3):736-757. Epub 2021 Jul 12.

Institute of Psychology, Faculty of Philosophy, Vilnius University, 3 Universiteto Str., LT-01513 Vilnius, Lithuania.

This study aimed to systematize the diverse and rather controversial findings of empirical research on the relationship between the temperament and academic achievement of school children, as well as to determine the average effect size between these variables. We included 57 original studies of published and unpublished research conducted in 12 countries between 1985 and 2019, with cumulative sample size of 79,913 (varying from 6333 to 14,126 for links between particular temperament dimensions and specific domains of achievement). A random-effects and mixed-effects model was fitted to the data for the central tendency of the temperament-achievement relation and for analyzing moderators, respectively. Read More

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State of the Art on the SARS-CoV-2 Toolkit for Antigen Detection: One Year Later.

Biosensors (Basel) 2021 Aug 31;11(9). Epub 2021 Aug 31.

Department of Chemical Science and Technologies, University of Rome "Tor Vergata", Via della Ricerca Scientifica, 00133 Rome, Italy.

The recent global events of COVID-19 in 2020 have alerted the world to the risk of viruses and their impacts on human health, including their impacts in the social and economic sectors. Rapid tests are urgently required to enable antigen detection and thus to facilitate rapid and simple evaluations of contagious individuals, with the overriding goal to delimitate spread of the virus among the population. Many efforts have been achieved in recent months through the realization of novel diagnostic tools for rapid, affordable, and accurate analysis, thereby enabling prompt responses to the pandemic infection. Read More

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Emerging evidence of Toll-like receptors as a putative pathway linking maternal inflammation and neurodevelopmental disorders in human offspring: a systematic review.

Brain Behav Immun 2021 Sep 22. Epub 2021 Sep 22.

Kids Neuroscience Centre, The Children's Hospital at Westmead, Faculty of Medicine and Health, University of Sydney, Sydney, Australia; The Children's Hospital at Westmead Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, Australia; Molecular Neurobiology Research Laboratory, Kids Research, Children's Hospital at Westmead, and The Children's Medical Research Institute, Westmead, New South Wales, Australia. Electronic address:

Inflammation is increasingly recognised to play a major role in gene-environment interactions in neurodevelopmental disorders (NDDs). The effects of aberrant immune responses to environmental stimuli in the mother and in the child can affect neuroimmune signalling that is central to brain development. Toll-like receptors (TLR) are the best known innate immune pattern and danger recognition sensors to various environmental threats. Read More

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September 2021

Estimated effect of increased diagnosis, treatment, and control of diabetes and its associated cardiovascular risk factors among low-income and middle-income countries: a microsimulation model.

Lancet Glob Health 2021 Sep 22. Epub 2021 Sep 22.

Institute for Applied Health Research, University of Birmingham, Birmingham, UK; Centre for Global Surgery, Department of Global Health, Stellenbosch University, Cape Town, South Africa; Medical Research Council-Wits University Rural Public Health and Health Transitions Research Unit, Faculty of Health Sciences, School of Public Health, University of the Witwatersrand, Johannesburg, South Africa.

Background: Given the increasing prevalence of diabetes in low-income and middle-income countries (LMICs), we aimed to estimate the health and cost implications of achieving different targets for diagnosis, treatment, and control of diabetes and its associated cardiovascular risk factors among LMICs.

Methods: We constructed a microsimulation model to estimate disability-adjusted life-years (DALYs) lost and health-care costs of diagnosis, treatment, and control of blood pressure, dyslipidaemia, and glycaemia among people with diabetes in LMICs. We used individual participant data-specifically from the subset of people who were defined as having any type of diabetes by WHO standards-from nationally representative, cross-sectional surveys (2006-18) spanning 15 world regions to estimate the baseline 10-year risk of atherosclerotic cardiovascular disease (defined as fatal and non-fatal myocardial infarction and stroke), heart failure (ejection fraction of <40%, with New York Heart Association class III or IV functional limitations), end-stage renal disease (defined as an estimated glomerular filtration rate <15 mL/min per 1·73 m or needing dialysis or transplant), retinopathy with severe vision loss (<20/200 visual acuity as measured by the Snellen chart), and neuropathy with pressure sensation loss (assessed by the Semmes-Weinstein 5·07/10 g monofilament exam). Read More

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September 2021

Challenges and solutions for diabetes early career researchers in the COVID-19 recovery - perspectives of the Diabetes UK Innovators in Diabetes.

Diabet Med 2021 Sep 25:e14698. Epub 2021 Sep 25.

Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, UK.

The COVID-19 pandemic has put diabetes at the forefront of conversation. The prevalence of type 2 diabetes in the UK is high and has links to adverse COVID-19 outcomes . Research investigating the links between these two public health issues are moving at pace. Read More

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September 2021

Feats, Flops, and Free Lessons from Nz's Response to the Covid-19 Pandemic.

Joanna M Manning

Med Law Rev 2021 Sep 25. Epub 2021 Sep 25.

Faculty of Law, University of Auckland, Auckland, New Zealand.

Beginning from the first reports of COVID-19 out of China, this article provides a commentary on the actions taken by the Government of New Zealand in terms of nine themes-a national response with an elimination goal, speed, and comprehensiveness of the initial response; an evidence-based, science-led approach, prioritised on protecting lives; effective communication; leadership style which appealed to collective responsibility and attempted to de-politicise the Government's response to the virus; flexibility of response characterised by 'learning as you go'; oversight of coercive state powers, including a pragmatic response which attempted to defuse conflict and reserved use of 'hard power' to a last resort; deployment of public health interventions, and health system adaptations; the impact on Māori and marginalised communities; and economic protection and stimulus-to identify factors that might help explain why New Zealand's pandemic response was successful and those which could have been managed better. The partially successful legal challenge brought to the four-and-a half week lockdown, the most stringent in the world, in Borrowdale v Director-General of Health, is also considered. Read More

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September 2021

Concerns and recommendations for using Amazon MTurk for eating disorder research.

Int J Eat Disord 2021 Sep 25. Epub 2021 Sep 25.

Charleston Area Medical Center - Institute for Academic Medicine, Charleston, West Virginia, USA.

Objective: Our original aim was to validate and norm common eating disorder (ED) symptom measures in a large, representative community sample of transgender adults in the United States. We recruited via Amazon Mechanical Turk (MTurk), a popular online recruitment and data collection platform both within and outside of the ED field. We present an overview of our experience using MTurk. Read More

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September 2021

Advanced Nanocellulose-Based Composites for Flexible Functional Energy Storage Devices.

Adv Mater 2021 Sep 24:e2101368. Epub 2021 Sep 24.

Department of Wood Technology and Wood-Based Composites, University of Göttingen, D-37077, Göttingen, Germany.

With the increasing demand for wearable electronics (such as smartwatch equipment, wearable health monitoring systems, and human-robot interface units), flexible energy storage systems with eco-friendly, low-cost, multifunctional characteristics, and high electrochemical performances are imperative to be constructed. Nanocellulose with sustainable natural abundance, superb properties, and unique structures has emerged as a promising nanomaterial, which shows significant potential for fabricating functional energy storage systems. This review is intended to provide novel perspectives on the combination of nanocellulose with other electrochemical materials to design and fabricate nanocellulose-based flexible composites for advanced energy storage devices. Read More

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September 2021

How are economic evaluations carried out for primary caries prevention strategies?

Henry Quach

Evid Based Dent 2021 Jan;22(3):90

Dental Core Trainee, Oral & Maxillofacial Surgery, Ninewells Hospital, Dundee, UK.

Aims To summarise evidence on economic evaluations (EEs) of primary caries prevention in preschool children aged 2-5 years and to evaluate the reporting quality of full EE studies using a quality assessment tool.Methods Systematic literature search from several databases. The reporting quality was assessed using the Consolidated Health Economic Evaluation Reporting Standards (CHEERS) checklist. Read More

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January 2021

First-line Medications for the Outpatient Treatment of Alcohol Use Disorder: A Systematic Review of Perceived Barriers.

J Addict Med 2021 Sep 22. Epub 2021 Sep 22.

Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada (CG, SLM, RM); Department of Family Medicine, McMaster University, Hamilton, Ontario, Canada (YC); Addiction Medicine Program, Homewood Specialized Services, Guelph, Ontario, Canada (YC); Schwartz/Reisman Emergency Medicine Institute, Toronto, Ontario, Canada (SLM, RM); Division of Emergency Medicine, Sinai Health, Toronto, Ontario, Canada (SLM); Department of Family and Community Medicine, Division of Emergency Medicine, University of Toronto, Toronto, Ontario, Canada (SLM); Division of Emergency Medicine, North York General Hospital, Toronto, Ontario, Canada (RM).

Objectives: Alcohol use disorder (AUD) is a common illness with significant health and economic consequences. Although three pharmacotherapeutic agents have been shown to decrease heavy drinking days among individuals with AUD, they are vastly underutilized in clinical practice. The objective of this review was to elucidate barriers that may prevent patients from obtaining medication for addiction treatment (MAT) for AUD in an outpatient or residential setting. Read More

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September 2021

Technology-induced job loss risk, disability and all-cause mortality in Norway.

Occup Environ Med 2021 Sep 24. Epub 2021 Sep 24.

Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway

Background: Ongoing shifts in economic structure from automation and globalisation can affect employment and mortality, yet these relations are not well described.

Objective: We assess whether long-term employment and health outcomes relate systematically to structural change in the labour market, using the occupational Routine Task Intensity (RTI) score as indicator of exposure is to risks of outsourcing and technology-induced job loss.

Methods: Using a cohort design and administrative data with national population coverage, we categorise all Norwegian employees in 2003 by the RTI score of their occupation and examine how this score correlates with employment and health outcomes measured in 2018 and 2019. Read More

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September 2021

Impact of household shocks on access to healthcare services in Kenya: a propensity score matching analysis.

BMJ Open 2021 Sep 24;11(9):e048189. Epub 2021 Sep 24.

School of Governance, Utrecht University Faculty of Law, Economics and Governance, Utrecht, The Netherlands.

Objective: This study examines the effects of household shocks on access to healthcare services in Kenya. Shocks are adverse events that lead to loss of household income and/or assets.

Design And Setting: The study used data from the Kenya Integrated Household Budget Survey 2015/2016, a nationally representative cross-sectional survey. Read More

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September 2021

The relationship between quality of life and fear of Turkish individuals during the COVID-19 pandemic: A cross-sectional study.

Arch Psychiatr Nurs 2021 Oct 8;35(5):472-478. Epub 2021 Jun 8.

Department of Nursing, Mersin University Faculty of Nursing, 33343 Mersin, Turkey.

Objective: In this study, it was aimed to determine the relationship between quality of life and the fear experienced due to the COVID-19 pandemic.

Method: This cross-sectional descriptive study was conducted with a total of 1060 participants from Turkey's 65 provinces. The research data were collected through an online questionnaire consisting of three parts: "Personal Information Form", "The Fear of COVID-19 Scale (FCS)" and "World Health Organization Life Quality Scale-Short Form (WHOQOL-BREF)". Read More

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October 2021

How much does the hospital stay for infusion of anti-CD19 CAR-T cells cost to the French National Health Insurance?

Bull Cancer 2021 Sep 21. Epub 2021 Sep 21.

Université Lyon, centre Léon-Bérard, GATE L-SE UMR 5824, 69008 Lyon, France; Human and Social Science Department, centre Léon-Bérard, 69008 Lyon, France; Haute Autorité de santé, Committee for Economic and Public Health Evaluation, 93200 Saint Denis, France. Electronic address:

Chimeric antigen receptor T-cells (CAR-T cells) have the potential to be a major innovation as a new type of cancer treatment, but are associated with extremely high prices and a high level of uncertainty. This study aims to assess the cost of the hospital stay for the administration of anti-CD19 CAR-T cells in France. Data were collected from the French Medical Information Systems Program (PMSI) and all hospital stays associated with an administrated drug encoded 9439938 (tisagenlecleucel, Kymriah®) or 9440456 (axicabtagene ciloleucel, Yescarta®) between January 2019 and December 2020 were included. Read More

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September 2021

Key elements and effects of cardiovascular disease management programs based on community-based participatory research: protocol for a scoping review.

Syst Rev 2021 Sep 24;10(1):256. Epub 2021 Sep 24.

Department of Nursing, Changwon National University, Gyeongnam, 51140, Republic of Korea.

Background: Cardiovascular diseases (CVDs) are health problems that demonstrate high death and prevalence rates, and exhibit large health inequalities across different socio-economic status. Although interest in community-based participatory research (CBPR) is increasing because of the efforts to improve health equity, not enough literature review has been conducted on CBPR-based CVD management programs. The objective of this scoping review is to identify the key elements that should be considered when developing CBPR-based CVD management programs, and explore the effects of CBPR-based CVD management programs. Read More

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September 2021

Histone deacetylase inhibitor AR-42 and achiral analogues kill malaria parasites in vitro and in mice.

Int J Parasitol Drugs Drug Resist 2021 Aug 23;17:118-127. Epub 2021 Aug 23.

Griffith Institute for Drug Discovery, Griffith University, Queensland, 4111, Australia. Electronic address:

Malaria is caused by infection with Plasmodium parasites and results in significant health and economic impacts. Malaria eradication is hampered by parasite resistance to current drugs and the lack of a widely effective vaccine. Compounds that target epigenetic regulatory proteins, such as histone deacetylases (HDACs), may lead to new therapeutic agents with a different mechanism of action, thereby avoiding resistance mechanisms to current antimalarial drugs. Read More

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Screening biorefinery pathways to biodiesel, green-diesel and propylene-glycol: A hierarchical sustainability assessment of process.

J Environ Manage 2021 Sep 21;300:113772. Epub 2021 Sep 21.

Escola de Química, Federal University of Rio de Janeiro, CT, E, Ilha do Fundão, Rio de Janeiro, RJ, 21941-909, Brazil.

Plant design implies the best choice among a set of feedstock-to-product process pathways. Multiple sustainability performance indicators can blur the decision, and existing sustainability assessment methods usually focus only on environmental life-cycle performance and corporate metrics or solely on the gate-to-gate process. It is relevant to incorporate integrated system analysis to address sustainability comprehensively. Read More

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September 2021

Chemical and biological tracking in decentralized sanitation systems: The case of artificial constructed wetlands.

J Environ Manage 2021 Sep 21;300:113799. Epub 2021 Sep 21.

Institute of Chemical Engineering Sciences, Foundation of Research & Technology Hellas (ICEHT/FORTH), 10 Stadiou St., Platani, 26504, Patras, Greece.

Given that the social and economic sustainability of rural areas is highly based on the protection of natural resources, biodiversity and human health, simple-operated and cost-effective wastewater treatment systems, like artificial constructed wetlands (CWs), are widely proposed for minimizing the environmental and human impact of both water and soil pollution. Considering that the optimization of wastewater treatment processes is vital for the reduction of effluents toxic potential, there is imperative need to establish appropriate management strategies for ensuring CW performance and operational efficiency. To this end, the present study aimed to assess the operational efficiency of a horizontal free water surface CW (HFWS-CW) located in a world heritage area of Western Greece, via a twelve-month duration Toxicity Identification Evaluation (TIE)-like approach, including both chemical and biological tracking tools. Read More

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September 2021

[Prevalence and associated factors of frailty in adults over 70 years in the community].

Aten Primaria 2021 Sep 21;53(10):102128. Epub 2021 Sep 21.

Departamento de Enfermería, Universidad de Alicante, Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL), Alicante, España; Unidad de Investigación en Cuidados y Servicios de Salud (Investén-isciii), Instituto de Salud Carlos III, Madrid, España; CIBER Fragilidad y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid, España.

Objective: To estimate the prevalence and analyze the factors associated with frailty syndrome, in adults ≥70 years old, belonging to a health center in Asturias.

Design: Observational cross-sectional study.

Participants: Adults ≥70 years of age. Read More

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September 2021

Factors associated with the utilization of reproductive health services among the Bangladeshi married women: Analysis of national representative MICS 2019 data.

Midwifery 2021 Sep 14;103:103139. Epub 2021 Sep 14.

Department of Psychology and Neuroscience, Dalhousie University, 1355 Oxford Street, Halifax NS B3H 4R2, Nova Scotia, Canada. Electronic address:

Objectives: We calculated the prevalence of reproductive health services utilization among the currently married non-pregnant women in Bangladesh and investigated its association with demographics and socio-economic factors.

Methods: Publicly available secondary country representative 2019 Multiple Indicator Cluster Survey (MICS) dataset was analyzed. A two-stage stratified random sampling technique was followed, and all administrative districts (N=64) of Bangladesh were covered in the MICS 2019. Read More

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September 2021

A randomized sham controlled comparison of once vs twice-daily intermittent theta burst stimulation in depression: A canadian rTMS treatment and biomarker network in depression (CARTBIND) study.

Brain Stimul 2021 Sep 21. Epub 2021 Sep 21.

Department of Psychiatry and Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, M5S 1A8, Canada; Centre for Mental Health and Krembil Research Institute, University Health Network, Toronto, M5T 0S8, Canada.

Background: Intermittent theta burst stimulation (iTBS) is a newer form of repetitive transcranial magnetic stimulation (rTMS) for patients with treatment resistant depression (TRD) that can increase treatment capacity. Applying multiple daily iTBS sessions may enable patients to achieve remission more rapidly.

Objective: /Hypothesis- We compared the efficacy and tolerability of a twice-daily versus once-daily iTBS protocol in patients with TRD. Read More

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September 2021

Food Acquisition and Shopping Patterns in the United States: Characteristics and Relation to BMI in FoodAPS.

J Acad Nutr Diet 2021 Sep 21. Epub 2021 Sep 21.

Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina. Electronic address:

Background: Previous studies examined the association between shopping distance, frequency, and store type separately.

Objectives: The objective is to explore food acquisition and shopping habits using multi-dimensional measures and examine its association with body mass index (BMI).

Design: A cross-sectional study was conducted. Read More

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September 2021


Ophthalmology 2021 Sep 21. Epub 2021 Sep 21.

Importance: Approximately 8 million Americans self-report vision loss and blindness (VL), potentially resulting in a significant economic burden.

Objective: Estimate the economic burden of VL in the US and by state.

Design: Analysis of secondary data sources (American Community Survey (ACS), American Time Use Survey, Bureau of Labor Statistics, Medical Expenditure Panel Survey (MEPS), National and State Health Expenditure Accounts (N/SHEA), National Health Interview Survey (NHIS)) using attributable fraction, regression, and other methods to estimate the incremental direct and indirect 2017 costs of VL. Read More

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September 2021

Community risk perception and barriers for the practice of COVID-19 prevention measures in Northwest Ethiopia: A qualitative study.

PLoS One 2021 24;16(9):e0257897. Epub 2021 Sep 24.

School of Medicine, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.

Background: According to the World Health Organization, viral diseases continue to emerge and represent a serious issue for public health. The elderly and those with underlying chronic diseases are more likely to become severe cases. Our study sets out to present in-depth exploration and analyses of the community's risk perception and barriers to the practice of COVID-19 prevention measures in South Gondar Zone, Northwest Ethiopia. Read More

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September 2021

Wilson's Disease: An Analysis of Health Care Use and Cost Burden of Commercially Insured Adults in the United States.

Hepatol Commun 2021 Sep 2. Epub 2021 Sep 2.

Division of Gastroenterology and Hepatology, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA.

The economic and health care use burdens of Wilson's disease (WD) are unknown. In this study, we aimed to quantify this health care resource use and economic burden. We performed a retrospective case-control analysis of individuals in the Truven Health MarketScan Commercial Claims database (2007-2017). Read More

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September 2021

Treatment options for progression or recurrence of glioblastoma: a network meta-analysis.

Cochrane Database Syst Rev 2021 May 4;5:CD013579. Epub 2021 May 4.

Department of Oncology, Addenbrooke's Hospital, Cambridge, UK.

Background: Glioblastoma (GBM) is a highly malignant brain tumour that almost inevitably progresses or recurs after first line standard of care. There is no consensus regarding the best treatment/s to offer people upon disease progression or recurrence. For the purposes of this review, progression and recurrence are considered as one entity. Read More

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Prevalence and correlates of university students' perceived stress in southwestern Saudi Arabia.

Medicine (Baltimore) 2021 Sep;100(38):e27295

Department of Family and Community Medicine, College of Medicine, King Khalid University, Abha, Saudi Arabia.

Abstract: The university period can be stressful for most students. It may be due to exposure to various stressors. Objectives: To establish the prevalence and factors associated with high perceived stress among university undergraduates in south-western Saudi Arabia. Read More

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September 2021