35 results match your criteria haze flattening

Partial corneal recovery following selective trabeculoplasty-induced keratopathy: Longitudinal analysis through scheimpflug imaging.

Am J Ophthalmol Case Rep 2021 Jun 26;22:101062. Epub 2021 Feb 26.

Glaucoma Unit, Hospital Medicina dos Olhos, 207, Salem Bechara Street, Osasco, São Paulo, 06018-180, Brazil.

Purpose: To report an uncommon case of hyperopic shift and corneal haze, flattening and thinning following a single session of selective laser trabeculoplasty (SLT), and provide longitudinal clinical data and serial analyses of corneal profile through Scheimpflug imaging. Furthermore, a careful literature review was undertaken to determine possible risk factors for this complication.

Observations: A 47-year-old woman presented with blurred vision and mild corneal edema and haze three days following routine SLT. Read More

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Mitomycin C Application After Corneal Cross-linking for Keratoconus Increases Stromal Haze.

J Refract Surg 2021 Feb;37(2):83-90

Purpose: To evaluate and compare corneal haze as determined by optical coherence tomography (OCT) after corneal cross-linking (CXL) for the treatment of mild to moderate keratoconus with or without mitomycin C (MMC) application.

Methods: This was a retrospective analysis of 87 eyes of 72 patients with mild to moderate keratoconus. The first group (n = 44 eyes) underwent CXL between June 2013 and January 2015 and the second group (n = 43 eyes) underwent CXL with MMC (CXL+MMC) between February and December 2015, both following the Dresden protocol. Read More

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February 2021

Three-year follow-up in advanced pediatric keratoconus: thin corneas may not have pachymetry properly assessed after crosslinking.

Int J Ophthalmol 2020 18;13(10):1561-1566. Epub 2020 Oct 18.

Department of Ophthalmology, Otorhinolaryngology, Head and Neck Surgery, Medical School of Ribeirão Preto, University of São Paulo, Ribeirão Preto 14049-900, Brazil.

Aim: To analyze the crosslinking (CXL) effects in pediatric keratoconus, and to identify the patients' corneal characteristics whose pachymetry could not be adequately evaluated by Scheimpflug method after procedure.

Methods: Consecutive pediatric patients with progressive keratoconus underwent CXL were included. Best-corrected visual acuity (BCVA) and spheric equivalent (SE) were measured before and after CXL. Read More

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October 2020

Prospective two year study of changes in corneal density following transepithelial pulsed, epithelium-off continuous and epithelium-off pulsed, corneal crosslinking for keratoconus.

Cont Lens Anterior Eye 2020 10 22;43(5):458-464. Epub 2020 Mar 22.

Department of Ophthalmology, New Zealand National Eye Centre, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.

Purpose: To compare the corneal densitometry changes after transepithelial pulsed (t-ACXL), epithelium-off continuous (c-ACXL) and epithelium-off pulsed (p-ACXL), accelerated corneal crosslinking for patients with progressive keratoconus.

Methods: Prospective, interventional case series at a university hospital tertiary referral center. Forty eyes received t-ACXL, 40 eyes received c-ACXL, and 40 eyes received p-ACXL. Read More

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October 2020

Late progressive corneal flattening, haze and visual loss after eccentric crosslinking for Pellucid marginal degeneration.

Am J Ophthalmol Case Rep 2020 Jun 22;18:100621. Epub 2020 Feb 22.

Sadalla Amin Ghanem Eye Hospital, Joinville, SC, Brazil.

Purpose: Pellucid marginal degeneration (PMD) is a rare disease that is often mistaken for keratoconus but can similarly be treated with corneal collagen crosslinking (CXL). We report a case followed though 6 years of progressive irregular corneal flattening and thinning in both eyes (OU) after eccentric CXL for PMD.

Observation: A 46-year-old man with bilateral PMD and corrected distance visual acuity (CDVA) of 20/20 (-2. Read More

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Corneal Cross-linking in Thin Corneas: 1-Year Results of Accelerated Contact Lens-Assisted Treatment of Keratoconus.

J Refract Surg 2019 Oct;35(10):642-648

Purpose: To evaluate the safety and efficacy of accelerated contact lens-assisted cross-linking (A-CACXL) for patients with keratoconus and thin corneas.

Methods: This retrospective study included consecutive patients undergoing A-CACXL for progressive keratoconus from 2015 to 2017. Patients with a minimum corneal thickness of 400 µm or less after epithelium removal who underwent A-CACXL (9 mW/cm for 10 minutes, using iso-osmolar 0. Read More

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October 2019

Phototherapeutic keratectomy.

Surv Ophthalmol 2020 Jan - Feb;65(1):79-108. Epub 2019 Jul 12.

Cornea, Cataract and Refractive Surgery Services, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India. Electronic address:

Phototherapeutic keratectomy is an excimer laser-based surgical procedure widely performed by corneal surgeons for treating anterior corneal stromal pathologies. Phototherapeutic keratectomy helps by ablating the corneal stroma, thereby improving corneal clarity and smoothening the surface. Transient discomfort and induced hyperopia from corneal flattening are the immediate postoperative concerns. Read More

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Corneal Scarring and Hyperopic Shift After Corneal Cross-linking for Corneal Ectasia After SMILE.

J Refract Surg 2018 Nov;34(11):779-782

Purpose: To report a case of severe corneal scarring and hyperopic shift after corneal cross-linking (CXL) for the treatment of ectasia following small incision lenticule extraction (SMILE).

Methods: Case report and literature review.

Results: A 35-year-old man was referred with severe unilateral corneal haze that developed after CXL. Read More

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November 2018

Survival Analysis of Corneal Densitometry After Collagen Cross-Linking for Progressive Keratoconus.

Cornea 2018 Nov;37(11):1449-1456

Cornea Service, Wills Eye Hospital, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA.

Purpose: To evaluate the history of densitometric data in patients with keratoconus undergoing corneal cross-linking.

Methods: Twenty-two eyes of 22 patients with keratoconus were included. Corneal tomography and densitometry measurements were performed before and after accelerated corneal cross-linking. Read More

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November 2018

Comparative analysis of safety and efficacy of photorefractive keratectomy versus photorefractive keratectomy combined with crosslinking.

Clin Ophthalmol 2018 30;12:783-790. Epub 2018 Apr 30.

Refractive Services, The Eye Foundation, Coimbatore, India.

Purpose: To assess the safety, efficacy, and refractive predictability of half-fluence accelerated corneal collagen crosslinking (CXL) applied concurrently with photorefractive keratectomy (PRK), and compare the results to standard PRK.

Setting: Refractive Services, The Eye Foundation, Coimbatore, India.

Design: Interventional comparative case series. Read More

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Corneal Inlays for Presbyopia Explanted Due to Corneal Haze.

J Refract Surg 2018 May;34(5):357-360

Purpose: To present 3 patients who required explantation of KAMRA inlays (AcuFocus, Inc., Irvine, CA) due to visual symptoms caused by postoperative corneal haze.

Methods: Case series. Read More

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Epithelium-on photorefractive intrastromal cross-linking (PiXL) for reduction of low myopia.

Clin Ophthalmol 2017 27;11:1205-1211. Epub 2017 Jun 27.

Eagle Eye Centre, Mount Alvernia Hospital.

Purpose: To report the 9-12-month outcomes of a novel procedure for reduction of low myopia through epithelium-on photorefractive intrastromal cross-linking (PiXL) with customized control of topographic distribution of ultraviolet (UV)-fluence.

Method: Myopic patients with normal (non-ectatic) corneas underwent the PiXL procedure for reduction of low myopia. PiXL treatments were delivered through selective application of UVA light based on the refractive error of each patient. Read More

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Effect of preoperative factors on visual acuity, corneal flattening, and corneal haze after accelerated corneal crosslinking.

J Cataract Refract Surg 2016 10;42(10):1483-1489

From the Ophthalmology Department (Koc, Uzel, Tekin, Kosekahya, Yilmazbas), Ulucanlar Eye Training and Research Hospital, and Dünyagöz Hospital (Ozulken), Ankara, Turkey.

Purpose: To evaluate the preoperative characteristics that might influence corneal flattening, visual acuity, and corneal haze after accelerated (9 mW/cm) corneal collagen crosslinking (CXL).

Setting: Ulucanlar Eye Hospital, Ankara, Turkey.

Design: Retrospective case series. Read More

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October 2016

Femtosecond Intrastromal Lenticular Implantation Combined With Accelerated Collagen Cross-Linking for the Treatment of Keratoconus--Initial Clinical Result in 6 Eyes.

Cornea 2015 Oct;34(10):1331-9

Phaco and Refractive Department, Nethradhama Superspeciality Eye Hospital, Bangalore, India.

Purpose: To evaluate the initial outcomes of femtosecond intrastromal lenticular implantation (FILI) combined with accelerated collagen cross-linking in patients with progressive keratoconus.

Methods: In this interventional, prospective, exploratory case series, patients with progressive keratoconus and contact lens intolerance were included. All eyes underwent femtosecond laser-enabled placement of stromal donor tissue and simultaneous accelerated collagen cross-linking. Read More

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October 2015

Transepithelial versus epithelium-off corneal cross-linking for the treatment of progressive keratoconus: a randomized controlled trial.

Am J Ophthalmol 2015 May 19;159(5):821-8.e3. Epub 2015 Feb 19.

Zonnestraal Eye Hospital Amersfoort, Amersfoort, Netherlands.

Purpose: To compare the clinical effects and safety of transepithelial corneal cross-linking (CXL) to epithelium-off (epi-off) CXL in progressive keratoconus.

Design: Randomized clinical trial (noninferiority).

Methods: Patients received either transepithelial CXL with Ricrolin TE (n = 35) or epi-off CXL with isotonic riboflavin (n = 26) in 1 academic treatment center, using a simple unrestricted randomization procedure. Read More

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Two-year accelerated corneal cross-linking outcome in patients with progressive keratoconus.

Biomed Res Int 2015 6;2015:325157. Epub 2015 Jan 6.

Department of Ophthalmology and Vision Rehabilitation, Medical University of Łódź, Żeromskiego 113, 90-549 Łódź, Poland.

Purpose: To evaluate the long-term results of accelerated corneal cross-linking (CXL) in patients with progressive keratoconus.

Methods: Sixteen patients underwent accelerated CXL at 6 mW/cm(2) for 15 minutes in one eye. The follow-up visits were scheduled on 7 days, 14 days, and 3, 12, and 24 months after the treatment. Read More

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October 2015

Additive effect of repeated corneal collagen cross-linking in keratoconus.

J Refract Surg 2014 Oct;30(10):716-8

Purpose: To report the long-term clinical outcome in a patient diagnosed as having bilateral progressive keratoconus who received a single corneal collagen cross-linking (CXL) treatment in the right eye and repeated CXL in the left eye.

Methods: Observational case report. Topographical changes were assessed by high-resolution Scheimpflug imaging. Read More

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October 2014

Characteristics influencing outcomes of corneal collagen crosslinking for keratoconus and ectasia: implications for patient selection.

J Cataract Refract Surg 2013 Aug;39(8):1133-40

Cornea and Laser Eye Institute-Hersh Vision Group, CLEI Center for Keratoconus, Teaneck, and the Department of Ophthalmology, UMDNJ New Jersey Medical School, Newark, New Jersey 07666, USA.

Purpose: To determine preoperative patient characteristics that may predict topography and visual acuity outcomes of corneal collagen crosslinking (CXL).

Setting: Cornea and refractive surgery practice.

Design: Cohort study. Read More

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Contact lens-induced keratitis resembling central toxic keratopathy syndrome.

Cornea 2009 Oct;28(9):1077-80

Moran Eye Center, University of Utah, Salt Lake City, Utah 84132, USA.

Purpose: To document a case of contact lens-induced keratitis resembling central toxic keratopathy syndrome.

Methods: A 23-year-old female developed an acute, central, stromal haze subsequent to soft contact lens overwear. Slit lamp examination revealed corrugated stromal "mud cracks," as seen in stage IV diffuse lamellar keratitis (DLK). Read More

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October 2009

Wavefront-supported photorefractive keratectomy with the Bausch & Lomb Zyoptix in patients with myopic astigmatism and suspected keratoconus.

J Refract Surg 2006 Jun;22(6):533-8

Department of Ophthalmology, Rabin Medical Center, Beilinson Campus, Petah Tiqwa, Israel.

Purpose: To evaluate the safety, efficacy, and visual outcome of wavefront-supported photorefractive keratectomy (PRK) for the correction of myopia and myopic astigmatism in patients with suspected keratoconus.

Methods: Forty eyes of 20 patients with myopia -4.0 to -8. Read More

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Early clinical experience using custom excimer laser ablations to treat irregular astigmatism.

J Cataract Refract Surg 2000 Oct;26(10):1442-50

Exilaser S.A., Bogota, Colombia.

Purpose: To assess the viability of custom excimer laser ablations for treating irregular astigmatism.

Setting: Single-center prospective study of a new custom-ablation technique.

Methods: Twelve patients received 15 custom ablations for irregular astigmatism resulting from keratoconus, penetrating keratoplasty for keratoconus, prior decentered laser in situ keratomileusis, or incisional refractive surgery. Read More

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October 2000

Healing after photorefractive keratectomy in cat eyes with a scanning mid-infrared Nd:YAG pumped optical parametric oscillator laser.

J Refract Surg 2000 Jan-Feb;16(1):32-9

IRVision, Inc., San Jose, CA 95131, USA.

Purpose: To evaluate the healing characteristics of cat corneas treated with a new scanning mid-infrared laser system.

Methods: Six adult cats were treated with 6-mm diameter photorefractive keratectomy (PRK) corrections. One eye in each animal was untreated as a control and the other was treated with either a -3. Read More

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Wound healing following anterior keratectomy and lamellar keratoplasty in the pig.

J Refract Surg 1999 Nov-Dec;15(6):636-47

Wake Forest University Eye Center, Winston-Salem, USA.

Purpose: To examine corneal wound healing in an animal model of two types of mechanical lamellar keratectomy.

Methods: One eye from each of 28 pigs was studied. Using a motorized keratome, corneas were subjected to an anterior lamellar keratectomy with removal of anterior stroma and epithelium, or to automated lamellar keratoplasty (ALK) with reapposition of a corneal flap. Read More

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February 2000

Corneal stromal wound healing in refractive surgery: the role of myofibroblasts.

Prog Retin Eye Res 1999 May;18(3):311-56

Department of Ophthalmology, The University of Texas Southwestern Medical Center at Dallas, 75235-9057, USA.

While laser and incisional refractive surgery offer the promise to correct visual refractive errors permanently and predictably, variability and complications continue to hinder wide-spread acceptance. To explain variations, recent studies have focused on the role of corneal wound healing in modulating refractive outcomes. As our understanding of the corneal response to refractive surgery broadens, it has become apparent that the response of one cell, the corneal stromal keratocyte, plays a pivotal role in defining the results of refractive surgery. Read More

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Predictability of radial keratotomy after excimer laser photorefractive keratectomy.

W J Jory

J Cataract Refract Surg 1998 Mar;24(3):312-4

London Centre for Refractive Surgery, England.

Purpose: To evaluate the results of radial keratotomy (RK) after photorefractive keratectomy (PRK).

Setting: London Centre for Refractive Surgery.

Methods: This study comprised six eyes having RK enhancement after PRK. Read More

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Glare sensitivity and visual acuity after excimer laser photorefractive keratectomy for myopia.

Br J Ophthalmol 1997 Feb;81(2):136-40

Eye Clinic, Cantonal Hospital, Lucerne, Switzerland.

Background: Following excimer laser photorefractive keratectomy (PRK), an increase in glare sensitivity and a reduction in contrast sensitivity can occur owing to changes in the cornea (structure and topography). In this study, an attempt was made to quantify and document objectively a change in those subjective perceptual factors.

Methods: Snellen visual acuity and disability glare were measured with the Berkeley glare test preoperatively as well as 1, 3, 6, 9, and 12 months postoperatively, after excimer laser photorefractive keratectomy (PRK) on 32 myopic patients (46 eyes). Read More

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February 1997

Contact lens fitting after photorefractive keratectomy.

Br J Ophthalmol 1996 Jul;80(7):597-603

Moorfields Eye Hospital, London.

Aims/background: This study evaluated contact lens fitting and the longer term response of the photorefractive keratectomy (PRK) cornea to lens wear. In PRK for myopia problems such as regression, anterior stromal haze, irregular astigmatism, halo aberration, and anisometropia have been reported. Certain patients therefore require contact lens correction to obtain best corrected visual acuity (BCVA). Read More

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Climatic proteoglycan stromal keratopathy, a new corneal degeneration.

Am J Ophthalmol 1995 Sep;120(3):330-41

El Maghraby Eye Hospital, Jeddah, Saudi Arabia.

Purpose: To characterize a previously undescribed corneal disorder, climatic proteoglycan stromal keratopathy.

Methods: We prospectively characterized the disorder in 58 eyes of 29 patients (ages 41 to 84 years) at the El Maghraby Eye Hospital, Jeddah Saudi Arabia. Light and transmission electron microscopy were performed on six corneal specimens. Read More

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September 1995

Myopic intrastromal photorefractive keratectomy with the neodymium-yttrium lithium fluoride picosecond laser in the cat cornea.

Arch Ophthalmol 1995 Apr;113(4):499-505

Department of Ophthalmology, New York Eye and Ear Infirmary, New York, USA.

Objective: To evaluate the refractive effects of myopic intrastromal photorefractive keratectomy (IPRK) with the neodymium-yttrium lithium fluoride (Nd-YLF) picosecond laser.

Methods: A 1053-nm Nd-YLF picosecond laser was used to produce myopic IPRK in cat corneas at threshold energy densities. Preoperative corneal topography and ultrasonic pachymetry were performed followed by IPRK in one eye each of 21 cats. Read More

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Multistep photorefractive keratectomy for high myopia.

Refract Corneal Surg 1993 Mar-Apr;9(2 Suppl):S37-41

Kim's Eye Center, Pusan, Korea.

Nineteen human myopic eyes exceeding -8.00 D underwent multi-step excimer laser photorefractive keratectomy (PRK) with 6-month follow up. We performed two or three step PRK at the same time according to the amount of myopia present. Read More

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