Br Dent J 2021 May 27. Epub 2021 May 27.
Université de Lyon - Université Claude Bernard Lyon 1, UMR CNRS 5615, Laboratoire des Multimatériaux et Interfaces, F-69622 Villeurbanne, France; Université de Lyon - Université Claude Bernard Lyon 1, Faculté d'Odontologie, 69008 Lyon, France; Hospices Civils de Lyon, Centre de Consultations et de Traitements Dentaires, 69007 Lyon, France.
Aim This systematic review aimed to critically summarise the results of clinical studies investigating agents able to: stop the progression of carious lesions; stop the development of new root carious lesions; preserve the vitality of the infected dental tissues; and increase the surface hardness or change of surface texture, in middle-age and older adults.Methods PubMed, Scopus, and Web of Science were searched systematically, following PRISMA guidelines. Clinical trials published from 2011 to 2020 (March) were included. Read More