2,959 results match your criteria hardness tissue

Coping strategies in response to different levels of elevated water hardness in channel catfish (Ictalurus punctatus): Insight into ion-regulatory and histopathological modulations.

Comp Biochem Physiol A Mol Integr Physiol 2021 Jul 20;260:111040. Epub 2021 Jul 20.

Department of Aquaculture and Fisheries, University of Arkansas at Pine Bluff, 1200 North University Drive, Pine Bluff 71601, AR, USA. Electronic address:

Water hardness above the optimal level can incite toxic effects in fish, which are often species specific. Hence, we aimed at obtaining insights on the potential effects of elevated water hardness as well as coping strategies in channel catfish (Ictalurus punctatus). First, a toxicity assay was performed where the 96 h-LC was calculated as 4939 mg/L CaCO. Read More

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[Quantitative evaluation of printing accuracy of multi-color and multi-hardness three-dimensional printing dental model with photopolymer jetting].

Zhonghua Kou Qiang Yi Xue Za Zhi 2021 Jul;56(7):652-658

Center of Digital Dentistry, Faculty of Prosthodontics, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China.

To quantitatively evaluate the accuracy of multi-color and multi-hardness dental models printed by using the photopolymer jetting (PJ) technology, and to provide protocol for the clinical application. A maxillary partially edentulous (Kennedy class Ⅱ subclass 1) standard digital model obtained through scanning and processing was selected as reference data. Five monochromatic DLP (digital light processing) models with single hardness were printed by printer DLP-800d based on DLP technology (DLP group), and five multi-color and multi-hardness PJ models were printed by printer J300Plus based on PJ technology (PJ group). Read More

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Are Radial Pressure Waves Effective in Treating Erectile Dysfunction? A Systematic Review of Preclinical and Clinical Studies.

Sex Med 2021 Jul 15;9(4):100393. Epub 2021 Jul 15.

Boston Medical Group, Bogotá, Colombia.

Introduction: Radial waves are used to treat erectile dysfunction; however, they are different than focal waves, and their mechanism of action or effect on improving this condition is not known.

Aim: To evaluate the effect of radial waves at the cellular level and their effectiveness at the clinical level for the treatment of erectile dysfunction.

Methods: Systematic literature review. Read More

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An Investigation of Regional Plantar Soft Tissue Hardness and Its Potential Correlation with Plantar Pressure Distribution in Healthy Adults.

Appl Bionics Biomech 2021 12;2021:5566036. Epub 2021 Jun 12.

Department of Orthopedics, Huashan Hospital, Fudan University, China.

Background: The plantar soft tissue plays a critical role in absorbing shocks and attenuating excessive stresses during walking. Plantar soft tissue property and plantar pressure are critical information for footwear design and clinical assessment. The aim of this study was to investigate the relationship between plantar soft tissue hardness and plantar pressure during walking. Read More

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Tribological, cytotoxicity and antibacterial properties of graphene oxide/carbon fibers/polyetheretherketone composite coatings on Ti-6Al-4V alloy as orthopedic/dental implants.

J Mech Behav Biomed Mater 2021 Jun 30;122:104659. Epub 2021 Jun 30.

School of Material Science and Engineering, Taiyuan University of Technology, Taiyuan, 030024, China. Electronic address:

In this work, graphene oxide/carbon fibers/polyetheretherketone (GO/CF/PEEK) composite coatings on Ti-6Al-4V (TC4) alloy were fabricated by electrostatic powder spraying method. The coatings with 0.02 wt% GO and 25 wt% CF were made to improve the wear resistance, cytocompatibility and antibacterial properties of the TC4 as orthopedic/dental implants. Read More

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Novel Approach to Tooth Chemistry. Quantification of the Dental-Enamel Junction.

Int J Mol Sci 2021 Jun 2;22(11). Epub 2021 Jun 2.

Department of Physics and Biophysics, Poznań University of Life Sciences, 60-637 Poznań, Poland.

The dentin-enamel junction (DEJ) is known for its special role in teeth. Several techniques were applied for the investigation of the DEJ in human sound molar teeth. The electron (EPMA) and proton (PIXE) microprobes gave consistent indications about the variability of elemental concentrations on this boundary. Read More

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Diagnostic accuracy of ultrasound shear wave elastography combined with superb microvascular imaging for breast tumors: A protocol for systematic review and meta-analysis.

Medicine (Baltimore) 2021 Jun;100(25):e26262

Ultrasound department of the First Affiliated Hospital of Dalian Medical University, Dalian, China.

Background: Shear wave elastography (SWE) is a new ultrasonic elastography technique for evaluating the hardness of living tissue by measuring the propagation velocity of shear wave in tissue, which is characterized by real-time, non-invasive and quantitative. The SWE technique can be used to diagnose the lesions of different tissues and organs, and the quantitative measurement of SWE is considered as more objective information about breast masses. Superb microvascular imaging (SMI) is a new noninvasive Doppler ultrasound imaging method, which can display blood flow information with high spatial resolution and high frame rate, while keeping the minimum low-speed blood flow components. Read More

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Ezh2 knockout in mesenchymal cells causes enamel hyper-mineralization.

Biochem Biophys Res Commun 2021 Aug 16;567:72-78. Epub 2021 Jun 16.

Department of Oral Biology, Rutgers School of Dental Medicine, NJ, USA. Electronic address:

Enhancer of zeste homolog 2 (EZH2) is the catalytic core of polycomb repressive complex 2 (PRC2), which primarily methylates lysine 27 on histone H3 (H2K27me3), generating transcriptionally suppressed heterochromatin. Since EZH2 suppresses expression of genes involved in dentin formation, we examined the role of EZH2 in tooth development. Intriguingly, microCT analysis of teeth from mice with conditional Ezh2 knockout in uncommitted mesenchymal cells showed hyper-mineralization of enamel, which is produced by the epithelial-lineage cells, ameloblasts. Read More

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Utility of Elastography for Differentiating Malignant and Benign Lymph Nodes During EBUS-TBNA: A Systematic Review and Meta-analysis.

J Bronchology Interv Pulmonol 2021 Jun 16. Epub 2021 Jun 16.

Departments of Pulmonary, Critical Care, and Sleep Medicine Biostatistics, All India Institute of Medical Sciences (AIIMS) Department of Pathology, VMMC and Safdarjung Hospital, New Delhi, India.

Background: Ultrasound elastography noninvasively estimates tissue hardness. Studies have evaluated elastography for differentiating malignant from benign lymph nodes during endobronchial ultrasound-guided transbronchial needle aspiration. Several methods of performing elastography are described with variable diagnostic accuracy. Read More

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Influence of protein and solid fat content on mechanical properties and comminution behavior of structured plant-based lipids.

Food Res Int 2021 07 19;145:110416. Epub 2021 May 19.

Department of Food Physics and Meat Science, Institute of Food Science and Biotechnology, University of Hohenheim, Garbenstr. 25, 70599 Stuttgart, Germany. Electronic address:

Recently an approach has been developed to structure plant-based lipids with the intention to mimic animal fat tissue in processed meat products or analogues. This study investigated the comminution behavior in a bowl chopper of such structured lipids with varying mechanical properties. For products like salami-type sausages these systems need to withstand comminution to yield particles for inclusion in product matrices. Read More

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A new teaching model with artificial teeth containing simulated pulpal tissue.

Dent Res J (Isfahan) 2021 17;18:19. Epub 2021 Mar 17.

Dental Student, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: This study aimed to evaluate the use of artificial teeth for endodontic training for dental students.

Materials And Methods: The following aspects of the artificial teeth were approved by the endodontists in Isfahan University of Medical Science: internal and external anatomy; coronal pulp chambers regarding their size, shape, and canal path; the root canals regarding their size, shape, and position; filling the pulp chamber and root canals by considering the texture, quantity, color, and ease of handling; and resin hardness and visualization of the radiographic image.

Results: The results showed favorable opinions regarding the internal and external anatomy, coronal pulp chamber, root canal (s), handling, and radiographic imaging. Read More

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Muscle fiber and fresh meat characteristics of white-striping chicken breasts, and its effects on palatability of sous-vide cooked meat.

Poult Sci 2021 Jul 11;100(7):101177. Epub 2021 Apr 11.

Department of Animal Sciences, Kyungpook National University, Sangju, South Korea. Electronic address:

The aim of this study was to compare the histochemical and meat quality characteristics between the normal and white-striping (WS) pectoralis major muscles. Additionally, this study investigated the effects of oven cooking (OV) and sous-vide (SV) cooking methods on objective texture parameters and sensory quality characteristics of the normal and WS chicken breast meats. Results showed that the WS condition broilers had higher body and breast weights (P < 0. Read More

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Self-assembling peptide hydrogel SPG-178 as a pancreatic fistula-preventing agent.

Langenbecks Arch Surg 2021 Jun 7. Epub 2021 Jun 7.

Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Yamadaoka 2-2, Suita, Osaka, 565-0871, Japan.

Purpose: Pancreatic fistula (PF) is a common and challenging complication after pancreatic surgery. The aim of this study was to investigate the efficacy of a new method for preventing PF utilizing self-assembling peptide hydrogel SPG-178 as a preclinical study.

Methods: The degradability of SPG-178 was confirmed by mixing it with protease. Read More

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Polyelectrolyte multilayer composite coating on 316 L stainless steel for controlled release of dual growth factors accelerating restoration of bone defects.

Mater Sci Eng C Mater Biol Appl 2021 Jul 14;126:112187. Epub 2021 May 14.

Department of Chemical Engineering and Biotechnology, National Taipei University of Technology (Taipei Tech), Taipei, Taiwan. Electronic address:

A composite coating of polyelectrolyte multilayers (PEMs) consisting of collagen, a chitosan barrier, and poly-γ-glutamic acid was fabricated using a spin coating technique to investigate and overcome the limited osseointegration capacity of 316 L stainless steel (316 L SS). To further enhance the biocompatibility, bone morphogenetic protein 2 (BMP-2) and basic fibroblast growth factor-2 (FGF-2) were loaded separately as dual growth factors, allowing for progressive drug release following the natural process of bone regeneration. The first burst release of FGF-2 triggered the proliferation of surrounding cells, and the subsequent release of BMP-2 stimulated their differentiation. Read More

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Effects of nitric oxide treatment on lignin biosynthesis and texture properties at wound sites of muskmelons.

Food Chem 2021 Nov 25;362:130193. Epub 2021 May 25.

College of Food Science and Engineering, Gansu Agricultural University, Lanzhou, China; Department of Postharvest Science of Fresh Produce, Agricultural Research Organization, Rishon LeZion, Israel.

Lignin is an important component of the healing tissue in fruits. In this study, we treated muskmelon (Cucumis melo L. cv. Read More

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November 2021

Cylindrical Polyurethane Scaffold Fabricated Using the Phase Inversion Method: Influence of Process Parameters on Scaffolds' Morphology and Mechanical Properties.

Materials (Basel) 2021 May 31;14(11). Epub 2021 May 31.

Biomedical Engineering Laboratory, Faculty of Chemical and Process Engineering, Warsaw University of Technology, Warynskiego 1, 00-645 Warsaw, Poland.

This work presents a method of obtaining cylindrical polymer structures with a given diameter (approx. 5 mm) using the phase inversion technique. As part of the work, the influence of process parameters (polymer hardness, polymer solution concentration, the composition of the non-solvent solution, process time) on the scaffolds' morphology was investigated. Read More

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Composite Scaffolds for Bone Tissue Regeneration Based on PCL and Mg-Containing Bioactive Glasses.

Biology (Basel) 2021 May 4;10(5). Epub 2021 May 4.

Department of Engineering "Enzo Ferrari", University of Modena and Reggio Emilia, Via P. Vivarelli 10, 41125 Modena, Italy.

Polycaprolactone (PCL) is widely used in additive manufacturing for the construction of scaffolds for tissue engineering because of its good bioresorbability, biocompatibility, and processability. Nevertheless, its use is limited by its inadequate mechanical support, slow degradation rate and the lack of bioactivity and ability to induce cell adhesion and, thus, bone tissue regeneration. In this study, we fabricated 3D PCL scaffolds reinforced with a novel Mg-doped bioactive glass (Mg-BG) characterized by good mechanical properties and biological reactivity. Read More

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Evaluation of interface pressure and temperature management in five wheelchair seat cushions and their effects on user satisfaction.

J Tissue Viability 2021 Aug 24;30(3):402-409. Epub 2021 May 24.

Department of Physiotherapy. University of Valencia, Spain; Group in Physiotherapy of the Ageing Processes: Socio-sanitary Strategies. Department of Physiotherapy. University of Valencia, Spain; Joint Research Unit IRIMED (La Fe- UV), Spain.

Background: Factors such as the manufacturing materials, shape or even the mechanical and thermal response of sitting Pressure Redistribution Support Surfaces (PRSS) can be potential contributors to pressure ulcers. However, few studies have compared a number of characteristics of the most frequently used devices.

Objective: To compare three potential contributors to pressure ulcers in five commercial PRSS: pressure redistribution, temperature and perceived comfort. Read More

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Is there a preferable management for root caries in middle-aged and older adults? A systematic review.

Br Dent J 2021 May 27. Epub 2021 May 27.

Université de Lyon - Université Claude Bernard Lyon 1, UMR CNRS 5615, Laboratoire des Multimatériaux et Interfaces, F-69622 Villeurbanne, France; Université de Lyon - Université Claude Bernard Lyon 1, Faculté d'Odontologie, 69008 Lyon, France; Hospices Civils de Lyon, Centre de Consultations et de Traitements Dentaires, 69007 Lyon, France.

Aim This systematic review aimed to critically summarise the results of clinical studies investigating agents able to: stop the progression of carious lesions; stop the development of new root carious lesions; preserve the vitality of the infected dental tissues; and increase the surface hardness or change of surface texture, in middle-age and older adults.Methods PubMed, Scopus, and Web of Science were searched systematically, following PRISMA guidelines. Clinical trials published from 2011 to 2020 (March) were included. Read More

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Effect of Zamzam Water on Microhardness of Primary Tooth Enamel After Erosion Induced by Claritin Syrup: An Study.

J Int Soc Prev Community Dent 2021 Mar-Apr;11(2):173-178. Epub 2021 Apr 15.

Preventive Dentistry Department, Umm Al-Qura University, Makkah, Saudi Arabia.

Background: Dental erosion is an irreversible damage to hard tissues in the mouth due to acid dissolution not induced by microorganisms. Oral medications contributed to the etiology of dental erosion. Among these medications, antihistamine-containing syrups were reported to have a considerable erosive effect on hard dental tissues. Read More

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Development of purified cashew gum mucoadhesive buccal tablets containing nystatin for treatment of oral candidiasis.

Drug Dev Ind Pharm 2021 May 7;47(5):825-837. Epub 2021 Jun 7.

Institute of Macromolecules, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

Objective: The objective of this work was to prepare mucoadhesive buccal tablets containing nystatin and purified cashew gum for the treatment of oral candidiasis.

Significance: Mucoadhesive buccal tablets containing the drug nystatin are an alternative to oral suspensions, which cause low therapeutic adherence to the treatment of oral candidiasis. Purified cashew gum has been studied as a diluent and mucoadhesive agent in tablets. Read More

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Biodegradable magnesium pins enhanced the healing of transverse patellar fracture in rabbits.

Bioact Mater 2021 Nov 27;6(11):4176-4185. Epub 2021 Apr 27.

Musculoskeletal Research Laboratory, Department of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Hong Kong SAR, China.

Displaced fractures of patella often require open reduction surgery and internal fixation to restore the extensor continuity and articular congruity. Fracture fixation with biodegradable magnesium (Mg) pins enhanced fracture healing. We hypothesized that fixation with Mg pins and their degradation over time would enhance healing of patellar fracture radiologically, mechanically, and histologically. Read More

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November 2021

Atlas of Human Skeleton Hardness Obtained Using the Micro-indentation Technique.

Orthop Surg 2021 Jun 11;13(4):1417-1422. Epub 2021 May 11.

The Third Hospital of Hebei Medical University, Shijiazhuang, China.

Objectives: Measure and systematically evaluate the distribution of microhardness in the human skeleton.

Methods: Three fresh corpses were obtained, aged 62 (male), 45 (female), and 58 years (male). Soft tissues were removed, and all axial and unilateral appendicular bones were freshly harvested. Read More

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AI driven feature extraction model for chest cavity spectrum signal visualization.

Haitao Niu Jihua Gu

Int J Speech Technol 2021 Apr 30:1-14. Epub 2021 Apr 30.

School of Optoelectronic Science and Engineering, Soochow University, Suzhou, 215006 China.

Lung cancer is the most fatal cancer in the world. Early detection, diagnosis and treatment of lung cancer is an important means to improve the survival rate of lung cancer patients. The early signs of lung cancer are small pulmonary nodules, so early detection and timely treatment of pulmonary nodules are of great significance to save the lives of lung cancer patients. Read More

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Ceria-Incorporated Biopolymer for Preventing Fungal Adhesion.

ACS Biomater Sci Eng 2021 05 4;7(5):1808-1816. Epub 2020 Dec 4.

Institute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan 31116, South Korea.

Although biopolymers are widely used in biomedical fields, the issue of poor antimicrobial properties remains unsolved, leading to a potential increase in infections. Here, ceria nanoparticles (CNPs) were incorporated into a representative biopolymer, poly(methyl methacrylate) (PMMA), for drug-free antimicrobial properties. After characterizing the CNPs and surface/mechanical properties of the CNP-PMMA nanocomposite, antiadhesive effects against , the most common fungal species responsible for fungal infections, were determined using metabolic activity assays, and the underlying microbial antiadhesive mechanism was revealed. Read More

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Oyster biomineralization under ocean acidification: From genes to shell.

Glob Chang Biol 2021 Aug 27;27(16):3779-3797. Epub 2021 May 27.

The Swire Institute of Marine Science and School of Biological Sciences, The University of Hong Kong, Pokfulam, Hong Kong SAR.

Biomineralization is one of the key processes that is notably affected in marine calcifiers such as oysters under ocean acidification (OA). Understanding molecular changes in the biomineralization process under OA and its heritability, therefore, is key to developing conservation strategies for protecting ecologically and economically important oyster species. To do this, in this study, we have explicitly chosen the tissue involved in biomineralization (mantle) of an estuarine commercial oyster species, Crassostrea hongkongensis. Read More

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3D Printing Improved Testicular Prostheses: Using Lattice Infill Structure to Modify Mechanical Properties.

Front Surg 2021 20;8:626143. Epub 2021 Apr 20.

Engineering Faculty, Queensland University of Technology, Brisbane, QLD, Australia.

Patients often opt for implantation of testicular prostheses following orchidectomy for cancer or torsion. Recipients of testicular prostheses report issues regarding firmness, shape, size, and position, aspects of which relate to current limitations of silicone materials used and manufacturing methods for soft prostheses. We aim to create a 3D printable testicular prosthesis which mimics the natural shape and stiffness of a human testicle using a lattice infill structure. Read More

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Shear wave elastography as a new, non-invasive diagnostic modality for the diagnosis of penile elasticity: a prospective multicenter study.

Ther Adv Urol 2021 Jan-Dec;13:17562872211007978. Epub 2021 Apr 19.

Andrology and Urogynecology Clinic, Santa Maria Terni Hospital, University of Perugia, Perugia, Italy.

Objective: Shear wave elastosonography (SWE) could be used to evaluate the elasticity of penile tissue. Few studies in the literature, however, have investigated its use in patients with erectile dysfunction (ED) or have attempted to correlate findings with International Index of Erectile Function (IIEF-5) scores. The primary aim of this study was to evaluate the characteristics of erectile tissue using SWE and to determine possible relationships with IIEF-5 and Erection Hardness Scale (EHS) scores. Read More

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Bioinspired buckling of scaled skins.

Bioinspir Biomim 2021 06 7;16(4). Epub 2021 Jun 7.

Department of Mechanical Engineering, McGill University, 817 Sherbrooke Street West, Montreal, QC H3A 2K6, Canada.

Natural flexural armors combine hard, discrete scales attached to soft tissues, providing unique combinations of surface hardness (for protection) and flexibility (for unimpeded motion). Scaled skins are now inspiring synthetic protective materials which offer attractive properties, but which still suffer from limited trade-offs between flexibility and protection. In particular, bending a scaled skin with the scales on the intrados side jams the scales and stiffen the system significantly, which is not desirable in systems like gloves where scales must cover the palm side. Read More

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A New Tactile Transfer Cell Using Magnetorheological Materials for Robot-Assisted Minimally Invasive Surgery.

Sensors (Basel) 2021 Apr 26;21(9). Epub 2021 Apr 26.

Department of Mechanical Engineering, The State University of New York, Korea (SUNY Korea), Incheon 21985, Korea.

This paper proposes a new type of tactile transfer cell which can be effectively applied to robot-assisted minimally invasive surgery (RMIS). The proposed tactile device is manufactured from two smart materials, a magnetorheological fluid (MRF) and a magnetorheological elastomer (MRE), whose viscoelastic properties are controllable by an external magnetic field. Thus, it can produce field-dependent repulsive forces which are equivalent to several human organs (or tissues) such as a heart. Read More

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