64 results match your criteria hammer mallet

Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders.

Biol Psychiatry 2021 Mar 23. Epub 2021 Mar 23.

Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, Illinois; Department of Psychiatry and Behavioral Sciences, North Shore University Health System, Evanston, Illinois.

Background: Sex differences in incidence and/or presentation of schizophrenia (SCZ), major depressive disorder (MDD), and bipolar disorder (BIP) are pervasive. Previous evidence for shared genetic risk and sex differences in brain abnormalities across disorders suggest possible shared sex-dependent genetic risk.

Methods: We conducted the largest to date genome-wide genotype-by-sex (G×S) interaction of risk for these disorders using 85,735 cases (33,403 SCZ, 19,924 BIP, and 32,408 MDD) and 109,946 controls from the PGC (Psychiatric Genomics Consortium) and iPSYCH. Read More

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Using an impact hammer to perform biomechanical measurements during osteotomies: Study of an animal model.

Proc Inst Mech Eng H 2021 Jul 23;235(7):838-845. Epub 2021 Apr 23.

CNRS, Laboratoire Modélisation et Simulation Multi Echelle, MSME UMR 8208 CNRS, Créteil Cedex, France.

Osteotomies are common surgical procedures used for instance in rhinoplasty and usually performed using an osteotome impacted by a mallet. Visual control being difficult, osteotomies are often based on the surgeon proprioception to determine the number and energy of each impact. The aim of this study is to determine whether a hammer instrumented with a piezoelectric force sensor can be used to (i) follow the displacement of the osteotome and (ii) determine when the tip of the osteotome arrives in frontal bone, which corresponds to the end of the osteotomy pathway. Read More

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Foot deformities in patients with diabetic mellitus (with and without peripheral neuropathy).

J Tissue Viability 2021 04 16. Epub 2021 Apr 16.

Department of Nursing, University of Malaga, Spain; Biomedical Research Institute (IBIMA), 29010, Malaga, Spain.

Background: Diabetic peripheral neuropathy (DPN) is one of the most common complications in diabetes mellitus. It is the disorder that most commonly affects the feet of people with diabetes. The aim of the present study is to determine the relationship between DPN and the presence of deformities in the foot. Read More

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[Research progress of interphalangeal arthrodesis].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2020 Sep;34(9):1195-1199

Department of Ankle Surgery, Tongji Hospital of Tongji University, Shanghai, 200065, P.R.China.

Objective: To review the research progress of interphalangeal arthrodesis in the treatment of interphalangeal joint deformity.

Methods: The literature about interphalangeal arthrodesis at home and abroad was extensively consulted, and the indications, fusion methods, fixation methods, complications, and so on were summarized and analysed.

Results: The indications of interphalangeal arthrodesis are hammer toe, claw toe, and mallet toe. Read More

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September 2020

Injury pattern and the biomechanical assessment of skull fracture risk in blows with a rubber mallet.

Forensic Sci Int 2020 Jul 23;312:110303. Epub 2020 Apr 23.

Institute of Legal Medicine, University of Halle-Wittenberg, Franzosenweg 1, 06112 Halle/Saale, Germany.

Acts of violence often result in blunt force trauma. On behalf of the court, forensic experts not only have to assess injuries in terms of morphology or severity, but they also have to give statements regarding the risk of potential fatal injuries. We describe a case of domestic violence where a man hit the head of his wife using a rubber mallet. Read More

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Mallet hallux injury: A case report and literature review.

Clin Imaging 2020 Jun 24;62:33-36. Epub 2020 Jan 24.

Department of Radiology, University of California San Diego, 408 Dickinson Street, Mail code 8226, San Diego, CA 92103, USA. Electronic address:

Mallet injury is associated with variable degrees of extensor hallucis longus tendon tearing, ultimately leading to the well-known mallet toe deformity; this entity, commonly described at the lesser toes and fingers, has rarely been reported at the hallux. We present a surgically proven case of mallet hallux injury with radiographic and magnetic resonance imaging assessment and review the literature, including clinical and radiological findings, along with basic treatment concepts. Read More

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Using an Impact Hammer to Estimate Elastic Modulus and Thickness of a Sample During an Osteotomy.

J Biomech Eng 2020 Jul;142(7)

CNRS, Laboratoire Modélisation et Simulation Multi-Echelle, UMR CNRS 8208, 61 Avenue du Général de Gaulle, Créteil 94010, France.

Performing an osteotomy with a surgical mallet and an osteotome is a delicate intervention mostly based on the surgeon proprioception. It remains difficult to assess the properties of bone tissue being osteotomized. Mispositioning of the osteotome or too strong impacts may lead to bone fractures which may have dramatic consequences. Read More

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The effect of needle tenotomy on hammer, mallet and claw toe deformities in patients with diabetes, a retrospective study.

J Clin Transl Endocrinol 2019 Dec 12;18:100208. Epub 2019 Oct 12.

Steno Diabetes Center Copenhagen, Niels Steensens Vej 2, 2820 Gentofte, Denmark.

Aim: The aim of this study was to evaluate outcomes of needle tenotomies as a treatment option for hammer, mallet and claw toes in patients with diabetes.

Methods: This was a retrospective study where all patients receiving flexor tendon tenotomy by needle at our outpatient clinic were identified through the electronic patient record system.

Results: A total of 81 patients that had 106 tenotomy procedures performed were identified. Read More

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December 2019

Forefoot disorders and conservative treatment.

Yeungnam Univ J Med 2019 05 14;36(2):92-98. Epub 2019 May 14.

Department of Physical Medicine and Rehabilitation, Yeungnam University College of Medicine, Daegu, Korea.

Forefoot disorders are often seen in clinical practice. Forefoot deformity and pain can deteriorate gait function and decrease quality of life. This review presents common forefoot disorders and conservative treatment using an insole or orthosis. Read More

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A polygenic resilience score moderates the genetic risk for schizophrenia.

Mol Psychiatry 2021 03 6;26(3):800-815. Epub 2019 Sep 6.

Psychiatric Genetic Epidemiology & Neurobiology Laboratory (PsychGENe Lab), Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, NY, USA.

Based on the discovery by the Resilience Project (Chen R. et al. Nat Biotechnol 34:531-538, 2016) of rare variants that confer resistance to Mendelian disease, and protective alleles for some complex diseases, we posited the existence of genetic variants that promote resilience to highly heritable polygenic disorders1,0 such as schizophrenia. Read More

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Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.

Nat Genet 2019 Jun;51(6):1068

Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, IL, USA.

In the HTML version of the article originally published, the author group 'The Schizophrenia Working Group of the Psychiatric Genomics Consortium' was displayed incorrectly. The error has been corrected in the HTML version of the article. Read More

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Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.

Nat Genet 2019 04 25;51(4):659-674. Epub 2019 Mar 25.

Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, IL, USA.

Transcriptomic imputation approaches combine eQTL reference panels with large-scale genotype data in order to test associations between disease and gene expression. These genic associations could elucidate signals in complex genome-wide association study (GWAS) loci and may disentangle the role of different tissues in disease development. We used the largest eQTL reference panel for the dorso-lateral prefrontal cortex (DLPFC) to create a set of gene expression predictors and demonstrate their utility. Read More

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Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia.

Am J Med Genet B Neuropsychiatr Genet 2019 04 23;180(3):223-231. Epub 2019 Feb 23.

Cognitive Genetics and Cognitive Therapy Group, Neuroimaging, Cognition & Genomics (NICOG) Centre & NCBES Galway Neuroscience Centre, School of Psychology and Discipline of Biochemistry, National University of Ireland Galway, Galway, Ireland.

Genome-wide association studies (GWASs) are highly effective at identifying common risk variants for schizophrenia. Rare risk variants are also important contributors to schizophrenia etiology but, with the exception of large copy number variants, are difficult to detect with GWAS. Exome and genome sequencing, which have accelerated the study of rare variants, are expensive so alternative methods are needed to aid detection of rare variants. Read More

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Comparison of Percutaneous Reduction and Pin Fixation in Acute and Chronic Pediatric Mallet Fractures.

J Pediatr Orthop 2019 Mar;39(3):146-152

Department of Orthopaedic Surgery, Texas Scottish Rite Hospital for Children and Children's Medical Center of Dallas, Dallas, TX.

Background: Although pediatric mallet fractures are more common than adult fractures, no techniques have focused on surgical fixation of pediatric mallet fractures. This study aims to describe the technique and results of percutaneous reduction and fixation in acute and chronic pediatric mallet fractures.

Methods: This is a retrospective review of 51 pediatric mallet fractures treated with percutaneous wire fixation from 2007 to 2014; 38 were acute fractures and 13 were chronic (>4 wk from injury). Read More

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Plantar Plate Injury and Angular Toe Deformity.

Foot Ankle Clin 2018 Dec 25;23(4):703-713. Epub 2018 Sep 25.

Orthopaedic Surgery, Tri-State Specialist, LLC, Suite 300, 2730 Pierce Street, Sioux City, IA 51104, USA.

Lesser toe plantar plate injuries at the metatarsophalangeal (MTP) joint are a common source of metatarsalgia. The second MTP joint is the most commonly affected digit. The fibrocartilaginous plantar plate is the most important static stabilizer of the MTP joint; high loading with weight bearing can lead to attritional plantar plate injuries. Read More

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December 2018

Claw toe.

J Med Imaging Radiat Oncol 2018 Oct;62 Suppl 1:126

Department of Radiology, Concord Repatriation General Hospital, Concord, New South Wales, Australia.

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October 2018

Effects of the Use of a Mallet during Bone Marrow Biopsy Collection on Specimen Quality: A Quality Improvement Project.

Ann Clin Lab Sci 2018 Jul;48(4):517-521

Department of Pathology and Laboratory Medicine, University of Texas McGovern Medical School at Houston, Houston, Texas, USA

Context: Avoiding procedure-related morphologic distortion such as fragmentation and crush artifact is critical in bone marrow diagnosis. Use of a hammer or mallet, although infrequent, is a known technique of advancing the biopsy needle during specimen collection.

Objectives: We performed a double-blinded, retrospective review of bone marrow biopsies collected by the Interventional Radiology department at our institution in order to assess specimen quality by using this technique. Read More

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Quantifying the force transmission through the pelvic joints during total hip arthroplasty: A pilot cadaveric study.

Clin Biomech (Bristol, Avon) 2018 10 20;58:69-73. Epub 2018 Jul 20.

Department of Orthopaedic Surgery, Wake Forest School of Medicine, Winston-Salem, NC 27157-1050, USA. Electronic address:

Background: Total hip arthroplasty is one of the most successful and cost effective procedures in orthopedics. The purpose of this study is to investigate force transmission through the sacroiliac joint as a possible source of post-operative pain after total hip arthroplasty through the following three questions: Does the ipsilateral sacroiliac joint, contralateral sacroiliac joint, or pubic symphysis experience more force during placement? Does the larger mallet used to seat the implant generate a higher force? Does the specimen's bone density or BMI alter force transmission?

Methods: A solid design acetabular component was impacted into five human cadaver pelves with intact soft tissues. The pressure at both sacroiliac joints and the pubic symphysis was measured during cup placement. Read More

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October 2018

Age at first birth in women is genetically associated with increased risk of schizophrenia.

Sci Rep 2018 07 5;8(1):10168. Epub 2018 Jul 5.

Australian Center for Precision Health, University of South Australia Cancer Research Institute, University of South Australia, Adelaide, SA, 5000, Australia.

Previous studies have shown an increased risk for mental health problems in children born to both younger and older parents compared to children of average-aged parents. We previously used a novel design to reveal a latent mechanism of genetic association between schizophrenia and age at first birth in women (AFB). Here, we use independent data from the UK Biobank (N = 38,892) to replicate the finding of an association between predicted genetic risk of schizophrenia and AFB in women, and to estimate the genetic correlation between schizophrenia and AFB in women stratified into younger and older groups. Read More

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Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes.


Cell 2018 06;173(7):1705-1715.e16

Schizophrenia and bipolar disorder are two distinct diagnoses that share symptomology. Understanding the genetic factors contributing to the shared and disorder-specific symptoms will be crucial for improving diagnosis and treatment. In genetic data consisting of 53,555 cases (20,129 bipolar disorder [BD], 33,426 schizophrenia [SCZ]) and 54,065 controls, we identified 114 genome-wide significant loci implicating synaptic and neuronal pathways shared between disorders. Read More

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Effects of Rhinoplasty on Labyrinthine Function.

Aesthet Surg J 2018 Oct;38(11):1172-1177

Department of Otorhinolaryngology, Istanbul Medipol University.

Background: Rhinoplasty is a common surgical procedure that is requested and accepted by patients for cosmetic and functional reasons. Osteotomies are performed on nasal bone, maxillary crest, or vomer to fix the deviations of the nasal dorsum or septum. During the percussion of the osteotomes with the surgical mallet, the vibration energy diffuses to the cranium. Read More

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October 2018

Estimation of Genetic Correlation via Linkage Disequilibrium Score Regression and Genomic Restricted Maximum Likelihood.

Am J Hum Genet 2018 06 10;102(6):1185-1194. Epub 2018 May 10.

Centre for Population Health Research, School of Health Sciences and Sansom Institute of Health Research, University of South Australia, Adelaide, SA 5000, Australia; School of Environmental and Rural Science, University of New England, Armidale, NSW 2351, Australia; Queensland Brain Institute, University of Queensland, Brisbane, QLD 4072, Australia. Electronic address:

Genetic correlation is a key population parameter that describes the shared genetic architecture of complex traits and diseases. It can be estimated by current state-of-art methods, i.e. Read More

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Conservative Management of Metatarsalgia and Lesser Toe Deformities.

Foot Ankle Clin 2018 Mar 11;23(1):9-20. Epub 2017 Nov 11.

Foot and Ankle Division, Department of Orthopedic Surgery, Duke University Medical Center, 2301 Erwin Road, Box 3000, Durham, NC 27710, USA. Electronic address:

There are several forefoot conditions that can result in metatarsal head pain. Various points of the gait cycle can predispose the metatarsal heads to pain based on intrinsic and extrinsic imbalances. Metatarsalgia can further be classified according to primary, secondary, or iatrogenic etiologies. Read More

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Foot problems in older women.

F Guidozzi

Climacteric 2017 Dec 21;20(6):518-521. Epub 2017 Sep 21.

a Department of Obstetrics and Gynecology, Faculty of Health Sciences , University of Witwatersrand , Parktown, Johannesburg , South Africa.

Between 20 and 45% of women aged over 65 years of age will develop one or more foot problems, which, although not specific to older women, are more common in that age group than in younger women. These include structural defects of the toes including hallux valgus, hammer, mallet or claw toes, skin disorders, fungal infection of the toes and toe nails, thickened toe nails, ulcers, fissures or cracks between the toes, corns and calluses, flat or high-arched feet. Foot pain is common and may be associated with other co-morbid diseases of the foot. Read More

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December 2017

The pathology and management of lesser toe deformities.

EFORT Open Rev 2016 Nov 13;1(11):409-419. Epub 2017 Mar 13.

Foot & Ankle Unit, Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, HA7 4LP, UK.

Deformities of the lesser toes are common and can be associated with significant morbidity. These deformities are often multiple, and numerous treatment strategies have been described in the literature.The goal of surgical treatment is to improve symptoms by restoring alignment and function, and avoiding recurrence. Read More

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November 2016

A Midterm Review of Lesser Toe Arthrodesis With an Intramedullary Implant.

Foot Ankle Spec 2017 Oct 27;10(5):458-464. Epub 2017 Apr 27.

Department of Podiatric Surgery, Park House Health Centre, Carlton, Nottingham, UK (JLH, AJM).

Lesser toe deformities are one of the most common conditions encountered by podiatric surgeons. When conservative treatments fail surgical correction is indicated. Many surgical options have been described to address the complex nature of these deformities but no perfect solution has been reported to date. Read More

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October 2017

Survey of hand surgeons' and therapists' perceptions of the benefit of common surgical procedures of the hand.

J Plast Surg Hand Surg 2018 Feb 18;52(1):1-6. Epub 2017 Apr 18.

d Department of Surgery , Central Finland Central Hospital , Jyväskylä , Finland.

Objective: The objectives of this survey were (1) to study if surgeons' perceptions of the benefit of six surgical procedures differ if they consider themselves as patients instead of treating a patient, (2) to evaluate the role of five predetermined factors that may influence decision-making, and (3) to assess how uniformly hand surgeons and hand therapists perceive the benefits of the surgical treatments.

Methods: The members of the national societies for Hand Surgery and Hand Therapy were asked to participate in the survey. Six patient cases with hand complaint (carpal tunnel syndrome, flexor tendon injury, dorsal wrist ganglion, thumb amputation, boxer's fracture, and mallet fracture) and a proposed operative procedure were presented, and the respondents rated the procedures in terms of the expected benefit. Read More

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February 2018

Genetic correlation between amyotrophic lateral sclerosis and schizophrenia.

Nat Commun 2017 03 21;8:14774. Epub 2017 Mar 21.

Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht 3584 CX, The Netherlands.

We have previously shown higher-than-expected rates of schizophrenia in relatives of patients with amyotrophic lateral sclerosis (ALS), suggesting an aetiological relationship between the diseases. Here, we investigate the genetic relationship between ALS and schizophrenia using genome-wide association study data from over 100,000 unique individuals. Using linkage disequilibrium score regression, we estimate the genetic correlation between ALS and schizophrenia to be 14. Read More

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