Am J Obstet Gynecol 2021 Jun 23. Epub 2021 Jun 23.
Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada; University of Toronto, Toronto, Ontario, Canada. Electronic address:
Background: Despite the growing integration of mandatory biopsies for correlative endpoints within oncology clinical trials, there is sparse data on patient-reported outcomes, perceptions and preferences.
Objective: (s): The aim of this study was to prospectively assess the impact of research biopsies on the quality of life in patients with gynecologic cancer, evaluate biopsy related patient-reported outcomes, symptoms, complications and determine factors associated with patients' willingness to undergo sequential biopsies.
Study Design: We conducted a prospective study in patients with gynecologic malignancies undergoing research biopsies between 2015 and 2019 at Princess Margaret Cancer Centre, a tertiary Canadian cancer centre (NCT02334761). Read More