10,398 results match your criteria guidelines obesity

The impact of atherosclerotic cardiovascular disease, dyslipidaemia and lipid lowering therapy on Coronavirus disease 2019 outcomes: an examination of the available evidence.

Curr Opin Lipidol 2021 Jun 9. Epub 2021 Jun 9.

The University of Manchester, Faculty of Biology, Medicine and Health Department of Endocrinology, The Christie Hospital NHS Foundation Trust University Department of Medicine, Manchester University Foundation Trust, Manchester Department of Diabetes, Endocrinology and Obesity Medicine, Salford Royal NHS Foundation Trust, Salford, UK.

Purpose Of Review: Coronavirus Disease 2019 (COVID19) has caused significant global morbidity and mortality, especially in persons with underlying cardiovascular disease. There have been concerns that lipid-lowering therapy (LLT) increases angiotensin-converting enzyme 2 levels. Conversely, pleiotropic effects of statins can theoretically protect against severe COVID19 infection, supporting evidence from other respiratory illnesses in which statin use probably confers benefit. Read More

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Screening for Sarcopenia (Physical Frailty) in the COVID-19 Era.

Int J Endocrinol 2021 21;2021:5563960. Epub 2021 May 21.

Department of Psychiatry, Teikyo University School of Medicine, Tokyo, Japan.

Although the numbers of aged populations have risen considerably in the last few decades, the current coronavirus disease 2019 (COVID-19) has revealed an extensive vulnerability among these populations. Sarcopenia is an age-related disorder that increases hospitalization, dependencies, and mortality in older adults. It starts to develop in midlife or even earlier as a result of unbalanced diet/poor nutrition and low levels of physical activity, in addition to chronic disorders such as obesity and diabetes mellitus. Read More

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Prevalence of the Metabolic Syndrome Among Batswana Adults in Urban and Semi-Urban Gaborone.

Diabetes Metab Syndr Obes 2021 4;14:2505-2514. Epub 2021 Jun 4.

Department of Sport Science, University of Botswana, Gaborone, Botswana.

Purpose: The metabolic syndrome (MetS) is on the rise in Sub-Saharan Africa, attributed to increased and uncontrollable urbanization accompanied by its lifestyle changes. Non-communicable diseases, such as hypertension, diabetes, and obesity, which are components of the (MetS) are also on the increase in Botswana. To date, no study has determined the prevalence of the MetS in the apparently healthy Batswana adults. Read More

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Evaluation of a Treatment-Dose Enoxaparin Protocol for Patients With Obesity.

J Pharm Pract 2021 Jun 10:8971900211022300. Epub 2021 Jun 10.

Center for Outcomes Research and Evaluation, Atrium Health's Carolinas Medical Center, Charlotte, NC, USA.

Background: Treatment-dose enoxaparin is not well studied in obese patients. Guidelines suggest that obese patients receiving enoxaparin therapy for acute venous thromboembolism (VTE) should receive a standard initial dose, 1 mg/kg, based on actual body weight. It is possible that this dosing strategy in obese patients may be overestimated, leading to a higher bleeding risk compared to non-obese patients. Read More

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Evaluation of the combined glucose-insulin and intravenous glucose tolerance tests for insulin dysregulation diagnosis in donkeys.

Equine Vet J 2021 Jun 10. Epub 2021 Jun 10.

Department of Animal Medicine and Surgery, University of Cordoba, Campus Rabanales, Road Madrid-Cadiz km 396, 14104, Cordoba, Spain.

Background: Insulin dysregulation (ID) and donkey metabolic syndrome (DMS) are common in this species. Contrary to horses, diagnostic guidelines compiling insulin cut-offs values and dynamic testing interpretations have not been reported for this species.

Objectives: To evaluate resting serum insulin concentrations, the combined glucose-insulin test (CGIT) and the glucose intravenous tolerance test (IVGTT) for the diagnosis of DMS with ID suspicion. Read More

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[CME Dermatology 23/Answers: Hidradenitis suppurativa].

Praxis (Bern 1994) 2021 Jun;110(8):471-472

Institut für Dermatologie und Venerologie, Stadtspital Waid und Triemli, Zürich.

CME Dermatology 23/Answers: Hidradenitis suppurativa Hidradenitis suppurativa (Acne inversa) is a chronic skin disease characterized by recurrent inflammatory nodules, abscesses, and scarring mainly in the intertriginous areas. The prevalence is estimated to be 0.05 to 4. Read More

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Obesity Measures and Definitions of Sarcopenic Obesity in Singaporean Adults - the Yishun Study.

J Frailty Aging 2021 ;10(3):202-210

Shiou-Liang Wee, Geriatric Education and Research Institute (GERI), 2 Yishun Central 2, Tower E Level 4 GERI Admin, 768024, Singapore, Phone: +65 6807 8011, Benedict Wei Jun Pang, Geriatric Education and Research Institute (GERI), 2 Yishun Central 2, Tower E Level 4 GERI Admin, 768024, Singapore, Phone: +65 6807 8030, (B.W.J. Pang) partment, World Health Organization, Geneva, Switzerland, E-mail:

Objectives: Due to the lack of a uniform obesity definition, there is marked variability in reported sarcopenic obesity (SO) prevalence and associated health outcomes. We compare the association of SO with physical function using current Asian Working Group for Sarcopenia (AWGS) guidelines and different obesity measures to propose the most optimal SO diagnostic formulation according to functional impairment, and describe SO prevalence among community-dwelling young and old adults.

Design: Obesity was defined according to waist circumference (WC), percentage body fat (PBF), fat mass index (FMI), fat mass/fat-free mass ratio (FM/FFM), or body mass index (BMI). Read More

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[The Relationship between Body Mass Index and Adult Acute Myeloid Leukemia].

Zhongguo Shi Yan Xue Ye Xue Za Zhi 2021 Jun;29(3):677-684

The First Clinical Medical College of Lanzhou University, Lanzhou 730000, Gansu Province, China.

Objective: To analysis the relationship between different BMI (body mass index) and the clinical characteristics, laboratory examination indexes of newly diagnosed adult patients with acute myeloid leukemia (AML), so as to investigate the effects of BMI to the efficacy of first induction chemotherapy.

Methods: The clinical data of 145 newly diagnosed adult AML patients treated in the First Hospital of Lanzhou University from August 2015 to August 2019 were retrospective analyzed. According to the guidelines for prevention and control of overweight and obesity in Chinese adults, the BMI (kg/m) of the selected AML patients before induction chemotherapy was calculated and the patients were divided into the low body mass group (BMI<18. Read More

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The challenges of an aging Tetralogy of Fallot population.

Expert Rev Cardiovasc Ther 2021 Jun 9. Epub 2021 Jun 9.

Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, California, USA.

Introduction: Advancements in surgery and management have resulted in a growing population of aging adults with tetralogy of Fallot (TOF). As a result, there has been a parallel growth in late complications associated with the sequelae from the underlying cardiac anomalies as well as the surgical and other interventional treatments.

Areas Covered: Here, we review challenges related to an aging population of patients with TOF, particularly late complications, and highlight advances in management and key areas for future research. Read More

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Stroke management in a Swiss community hospital - in close collaboration with a stroke centre.

Swiss Med Wkly 2021 May 7;151:w20490. Epub 2021 Jun 7.

Department of Medicine, Medical Clinic, Spital Uster, Switzerland.

Background: Despite the universal recognition that stroke is a major burden of public health in developed countries, little is known concerning its epidemiology and care outside of stroke centres. The objective of our study was to provide information concerning risk factors for stroke, stroke management and quality of care in a community hospital in Switzerland.

Methods: Retrospective observational in-hospital study of adult stroke patients treated in a community hospital in Switzerland in collaboration with a nearby stroke centre. Read More

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Multimorbidity phenotypes in patients presenting to the emergency department with possible acute coronary syndrome.

Heart Lung 2021 Jun 4;50(5):648-653. Epub 2021 Jun 4.

University of California Los Angeles School of Nursing, Los Angeles, CA, United States.

Background: Multimorbidity (> 2 conditions) increases the risk of adverse outcomes and challenges health care systems for patients with acute coronary syndrome (ACS). These complications may be partially attributed to ACS clinical care which is driven by single-disease-based practice guidelines; current guidelines do not consider multimorbidity.

Objectives: To identify multimorbidity phenotypes (combinations of conditions) with suspected ACS. Read More

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Intraoperative Monitoring of the Obese Patient Undergoing Surgery: A Narrative Review.

Adv Ther 2021 Jun 5. Epub 2021 Jun 5.

University of Campania "Luigi Vanvitelli", Naples, Italy.

With the increasing prevalence of obesity in the population, anaesthetists must confidently manage both the pathophysiological and technical challenges presented in bariatric and non-bariatric surgery. The intraoperative period represents an important opportunity to optimise and mitigate risk. However, there is little formal guidance on what intraoperative monitoring techniques should be used in this population. Read More

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Cardiovascular risk prediction in type 2 diabetes before and after widespread screening: a derivation and validation study.

Lancet 2021 Jun 2;397(10291):2264-2274. Epub 2021 Jun 2.

School of Population Health, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand. Electronic address:

Background: Until recently, most patients with diabetes worldwide have been diagnosed when symptomatic and have high cardiovascular risk, meaning most should be prescribed cardiovascular preventive medications. However, in New Zealand, a world-first national programme led to approximately 90% of eligible adults being screened for diabetes by 2016, up from 50% in 2012, identifying many asymptomatic patients with recent-onset diabetes. We hypothesised that cardiovascular risk prediction equations derived before widespread screening would now significantly overestimate risk in screen-detected patients. Read More

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The Italian Consensus on minimally invasive simultaneous resections for synchronous liver metastasis and primary colorectal cancer: A Delphi methodology.

Updates Surg 2021 Jun 5. Epub 2021 Jun 5.

Department of Surgery, Regional Hospital of Treviso, Treviso, Italy.

At the time of diagnosis synchronous colorectal cancer, liver metastases (SCRLM) account for 15-25% of patients. If primary tumour and synchronous liver metastases are resectable, good results may be achieved performing surgical treatment incorporated into the chemotherapy regimen. So far, the possibility of simultaneous minimally invasive (MI) surgery for SCRLM has not been extensively investigated. Read More

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Effect of aging on clinical features and metabolic complications of women with polycystic ovary syndrome.

J Endocrinol Invest 2021 Jun 5. Epub 2021 Jun 5.

Section of Endocrinology, Department of Clinical and Experimental Medicine, University Hospital of Pisa, Via Paradisa, 2, 56124, Pisa, Italy.

Purpose: To assess the distribution of clinical features and metabolic abnormalities of polycystic ovary syndrome (PCOS) women according to their age.

Methods: Retrospective study on 602 women (mean age 23.9 ± 6. Read More

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Clinical risk factors associated with radiographic osteoarthritis progression among people with knee pain: a longitudinal study.

Arthritis Res Ther 2021 Jun 4;23(1):160. Epub 2021 Jun 4.

Faculty of Medicine and Health, Discipline of Physiotherapy, The University of Sydney, Sydney, Australia.

Background: The aim of this study was to identify modifiable clinical factors associated with radiographic osteoarthritis progression over 1 to 2 years in people with painful medial knee osteoarthritis.

Methods: A longitudinal study was conducted within a randomised controlled trial, the "Long-term Evaluation of Glucosamine Sulfate" (LEGS study). Recruitment occurred in 2007-2009, with 1- and 2-year follow-up assessments by blinded assessors. Read More

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The utility of deep brain stimulation surgery for treating eating disorders: A systematic review.

Surg Neurol Int 2021 19;12:169. Epub 2021 Apr 19.

Department of Basic Sciences, Touro University Nevada College of Osteopathic Medicine, Henderson, Nevada, United States.

Background: Deep brain stimulation (DBS) has demonstrated preliminary success as a treatment for neuropsychological disorders including obsessive-compulsive disorder and substance use disorder. This systematic review aims to assess the use of DBS in treating eating disorders (EDs) to determine its utility and the extent of adverse effects.

Methods: A PubMed search following PRISMA guidelines was executed to find studies encompassing DBS as a treatment of ED. Read More

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Use of Thyroid Hormones in Hypothyroid and Euthyroid Patients: A Thesis* Questionnaire Survey of Romanian Physicians *Thesis: Treatment of Hypothyroidism in Europe by Specialists: an International Survey.

Acta Endocrinol (Buchar) 2020 Oct-Dec;16(4):462-469

"Carol Davila" University of Medicine and Pharmacy - Endocrinology, Bucharest, Romania.

Objective: Romania has no national guidelines for hypothyroidism treatment, nor are there any recommendations from national societies to adhere to international guidelines. Our aim was to identify the attitudes of Romanian physicians relating to hypothyroidism treatment focusing on available formulations of levothyroxine (LT4).

Methods: All 748 members of the Romanian Society of Endocrinology were invited to participate in a web-based survey. Read More

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High prevalence of overall overweight/obesity and abdominal obesity amongst adolescents: An emerging nutritional problem in rural high schools in Limpopo Province, South Africa.

Afr J Prim Health Care Fam Med 2021 May 18;13(1):e1-e9. Epub 2021 May 18.

Department of Public Health, School of Health Care Sciences, Sefako Makgatho Health Sciences University, Ga-Rankuwa.

Background: As the gap in nutritional profiles between urban and rural rapidly reduces because of nutrition transition, rural adolescents are likely to engage in urban lifestyle behaviours.

Aim: The study determined the prevalence of overweight/obesity amongst adolescents in rural high schools and the association with selected factors.

Setting: Fetakgomo Municipality in rural Limpopo Province, South Africa. Read More

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The daily self-weighing for obesity management in primary care study: Rationale, design and methodology.

Contemp Clin Trials 2021 May 31;107:106463. Epub 2021 May 31.

Department of Health Behavior, School of Public Health, University of Alabama at Birmingham, 1665 University Boulevard, Birmingham, AL 35233, USA. Electronic address:

Background Daily self-weighing (DSW) may be an effective harm-reduction intervention to disrupt continued weight gain. Self-Weighing for Obesity Management in Primary Care (SWOP) is a 24-month randomized controlled trial in 400 adults with obesity (BMI: kg/m ≥ 30) receiving primary care through a clinical network affiliated with an academic medical center. Objective To test DSW as a potentially scalable way to deter age-related weight gain among primary care patients with obesity. Read More

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Objectively Measured Physical Activity and Body Fatness: Associations with Total Body Fat, Visceral Fat, and Liver Fat.

Med Sci Sports Exerc 2021 May 28. Epub 2021 May 28.

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands Department of Nutrition and Movement Sciences, Maastricht University Medical Center, Maastricht, The Netherlands MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.

Purpose: It remains unclear to what extent habitual physical activity and sedentary time are associated with visceral fat and liver fat. We studied substitution of sedentary time with time spent physically active and total body fat (TBF), visceral adipose tissue (VAT) and hepatic triglyceride content (HTGC) in middle-aged men and women.

Design: In this cross-sectional analysis of the Netherlands Epidemiology of Obesity study, physical activity was assessed in 228 participants using a combined accelerometer and heart rate monitor. Read More

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Systematic review and meta-analysis on prevalence of metabolic syndrome in psoriatic arthritis, rheumatoid arthritis and psoriasis.

Int J Rheum Dis 2021 Jun 2. Epub 2021 Jun 2.

Rheumatology Department, Campbelltown Hospital, Campbelltown, NSW, Australia.

Background: Psoriatic arthritis (PsA), rheumatoid arthritis (RA) and psoriasis (PsO) are associated with systemic inflammation and increased cardiovascular mortality and morbidity. Metabolic syndrome (MetS) is associated with systemic inflammation, and conditions associated with MetS, such as obesity, are associated with difficulty in attaining minimal disease activity (MDA) in individuals with inflammatory arthritis. This systematic review aims to determine whether there is an increased prevalence of MetS in PsA populations compared with PsO and RA populations. Read More

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Hypertension in the Middle East: current state, human factors, and barriers to control.

J Hum Hypertens 2021 Jun 1. Epub 2021 Jun 1.

Department of Medicine, Saint George Hospital University Medical Center, Beirut, Lebanon.

Hypertension is the leading source of morbidity and death. In the 21st century, there still is a major gap between high and low to middle-income countries in awareness, management, and control; countries in the Middle East represent an example of such disparities. In this review of the literature, light is shed on the prevalence and modifiable risk factors of hypertension specific to the region, as well as regional disparities in diagnosis and management. Read More

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Relationship between BMI with percentage body fat and obesity in Singaporean adults - The Yishun Study.

BMC Public Health 2021 Jun 1;21(1):1030. Epub 2021 Jun 1.

Geriatric Education and Research Institute (GERI), 2 Yishun Central 2, Tower E Level 4 GERI Admin, Singapore, 768024, Singapore.

Background: The main aim of this study was to the determine relationship between Body Mass Index (BMI) and percentage body fat (BF%) in Singaporean adults, derive a prediction model to estimate BF%, and to report population BF%. The secondary aim was to determine the prevalence of overweight and obesity based on BF% threshold and the new risk categories for obesity in Singaporean population.

Methods: This was a population-based study of 542 community-dwelling Singaporeans (21-90 years old, 43. Read More

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Home food environment and associations with weight and diet among U.S. adults: a cross-sectional study.

BMC Public Health 2021 Jun 1;21(1):1032. Epub 2021 Jun 1.

Emory Prevention Research Center, Rollins School of Public Health, Emory University, 1518 Clifton Road NE, Atlanta, GA, 30322, USA.

Background: The home provides the physical and social context for the majority of eating behaviors for U.S. adults. Read More

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Reference Intervals of Thyroid Function Tests Assessed by Immunoassay and Mass Spectrometry in Healthy Pregnant Women Living in Catalonia.

J Clin Med 2021 May 31;10(11). Epub 2021 May 31.

Endocrine, Thyroid & Obesity Research Group, Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol, s/n Camí de les Escoles, 08916 Badalona, Spain.

Background: Recent guidelines recommend establishing a local reference interval (RI) for thyroid function. We aimed to establish trimester-specific RIs for thyrotropin (TSH) and free thyroxine (FT4) in a cohort of healthy pregnant women in Catalonia (Spain).

Methods: A prospective observational study was conducted with 332 healthy pregnant women, from the first trimester (1T) to delivery. Read More

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Lifestyle Habits and Health Indicators in Migrants and Native Schoolchildren in Chile.

Int J Environ Res Public Health 2021 May 29;18(11). Epub 2021 May 29.

Facultad de Ciencias Médicas, Universidad de Santiago de Chile, Santiago 9170020, Chile.

In Chile, the migrant population has increased in the last years. Migrants adopt behaviors of this new culture, which can have an effect on their health. Contradictory results regarding differences between migrant and native children have been reported. Read More

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Effects of Hyperglycemia and Diabetes Mellitus on Coagulation and Hemostasis.

J Clin Med 2021 May 29;10(11). Epub 2021 May 29.

Department of Anesthesiology, Amsterdam UMC location AMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.

In patients with diabetes, metabolic disorders disturb the physiological balance of coagulation and fibrinolysis, leading to a prothrombotic state characterized by platelet hypersensitivity, coagulation disorders and hypofibrinolysis. Hyperglycemia and insulin resistance cause changes in platelet number and activation, as well as qualitative and/or quantitative modifications of coagulatory and fibrinolytic factors, resulting in the formation of fibrinolysis-resistant clots in patients with diabetes. Other coexisting factors like hypoglycemia, obesity and dyslipidemia also contribute to coagulation disorders in patients with diabetes. Read More

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Fruit Juices: Are They Helpful or Harmful? An Evidence Review.

Nutrients 2021 May 27;13(6). Epub 2021 May 27.

Non-Diet Nutrition, Shirenewton NP16 6RL, UK.

Dietary guidelines often deal with 100% fruit juice (FJ) inconsistently because it represents a source of free sugars. However, FJ also provides bioavailable micronutrients and plant bioactives at levels similar to those found in whole fruits. The present review weighs up the evidence from high-quality studies investigating a potential health harm for FJ against evidence from studies which indicate a potential health benefit. Read More

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Prevalence of Metabolic Syndrome in Children and Adolescents with Type 1 Diabetes Mellitus and Possibilities of Prevention and Treatment: A Systematic Review.

Nutrients 2021 May 23;13(6). Epub 2021 May 23.

Department of Bromatology, Faculty of Pharmacy with the Division of Laboratory Medicine, Medical University of Białystok, Mickiewicza 2D Street, 15-222 Białystok, Poland.

Overweight and obesity are an increasingly common problem, not only among the healthy population, but also in adolescents with type 1 diabetes (T1DM). Excess body weight is related to many cardiometabolic complications as well as a high risk of metabolic syndrome (MetS). The purpose of this systematic review is to provide a concise and critical overview of the prevalence of MetS in children and adolescents with T1DM and, ultimately, to discuss prevention and treatment options. Read More

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