55 results match your criteria gsp curriculum


Effect of Sea Buckthorn on Plasma Glucose in Individuals with Impaired Glucose Regulation: A Two-Stage Randomized Crossover Intervention Study.

Foods 2021 Apr 8;10(4). Epub 2021 Apr 8.

Department of Nutrition and Food Hygiene, School of Public Health, Peking University Health Science Center, Beijing 100191, China.

Sea buckthorn (SB) has been indicated to have hypoglycemic potential, but its effects on glucose in people with impaired glucose regulation (IGR) are still unclear. This work presents a randomized, double-blinded, two-way crossover study. A total of 38 subjects with IGR completed the intervention of consuming sea buckthorn fruit puree (SBFP, 90 mL/day, five weeks), washing out (four weeks), and then consuming placebo (90 mL/day, five weeks) or in reverse order. Read More

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A systematic review of global surgery partnerships and a proposed framework for sustainability.

Can J Surg 2021 04 28;64(3):E280-E288. Epub 2021 Apr 28.

From the Department of Surgery, Division of General Surgery, University of British Columbia, Vancouver, BC (Jedrzejko, Margolick, Ball-Banting); the Faculty of Medicine, University of Toronto, Toronto, Ont. (Nguyen); the Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ont. (Ding); the Department of Surgery, Makerere University, Kampala, Uganda (Kisa); and Trauma Services, Vancouver General Hospital, Vancouver, BC (Hameed, Joos).

Background: Building surgical capacity through global surgery partnerships (GSPs) between high and low- and middle-income countries (LMICs) is a rising global health focus. Our aim was to conduct a systematic review to characterize strategies employed by GSPs to build capacity and promote sustainability and to propose a novel reproducible model for sustainability.

Methods: We conducted a systematic review according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Read More

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Moving toward a competency-based curriculum: Analyzing patients' information and students' evaluation in geriatric dentistry.

J Dent Educ 2021 Apr 16. Epub 2021 Apr 16.

Thungyai Hospital, Nakhon Si Thammarat, Thailand.

Objective: There is no core competency for geriatric dentistry and special patient care (GSP) in Thailand. Therefore, GSP program was developed as a knowledge-based curriculum. This study aimed to describe the development and architecture of the GSP curriculum by analyzing patients' information and students' evaluation to move toward a competency-based curriculum. Read More

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Cutting Edge of the Pathogenesis of Atopic Dermatitis: Sphingomyelin Deacylase, the Enzyme Involved in Its Ceramide Deficiency, Plays a Pivotal Role.

Authors:
Genji Imokawa

Int J Mol Sci 2021 Feb 5;22(4). Epub 2021 Feb 5.

Center for Bioscience Research & Education and Utsunomiya University, 350 Mine Utsunomiya, Tochigi 321-8505, Japan.

Atopic dermatitis (AD) is characterized clinically by severe dry skin and functionally by both a cutaneous barrier disruption and an impaired water-holding capacity in the stratum corneum (SC) even in the nonlesional skin. The combination of the disrupted barrier and water-holding functions in nonlesional skin is closely linked to the disease severity of AD, which suggests that the barrier abnormality as well as the water deficiency are elicited as a result of the induced dermatitis and subsequently trigger the recurrence of dermatitis. These functional abnormalities of the SC are mainly attributable to significantly decreased levels of total ceramides and the altered ceramide profile in the SC. Read More

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February 2021

Improving Geropsychology Competencies of Veterans Affairs Psychologists.

J Am Geriatr Soc 2021 Mar 16;69(3):798-805. Epub 2021 Jan 16.

Palo Alto Geriatric Research, Education, and Clinical Center, VA Palo Alto, Health Care System, Palo Alto, California, USA.

Older adults are more likely to seek mental health care through integrated care settings such as primary care. Currently, there exists a significant shortage of mental health providers trained in geropsychology and integrated care competencies. To address this need within the Veterans Health Administration, a national workforce development program was extended to include psychologists, which is called the Geriatric Scholars Program-Psychology Track (GSP-P). Read More

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Advanced Glycation End Product Inhibitor Pyridoxamine Attenuates IVD Degeneration in Type 2 Diabetic Rats.

Int J Mol Sci 2020 Dec 19;21(24). Epub 2020 Dec 19.

Orthopaedic Stem Cell Research Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.

Type 2 diabetes mellitus (T2DM) is associated with advanced glycation end product (AGE) enrichment and considered a risk factor for intervertebral disc (IVD) degeneration. We hypothesized that systemic AGE inhibition, achieved using pyridoxamine (PM), attenuates IVD degeneration in T2DM rats. To induce IVD degeneration, lumbar disc injury or sham surgery was performed on Zucker Diabetic Sprague Dawley (ZDSD) or control Sprague Dawley (SD) rats. Read More

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December 2020

Orbital-free quantum crystallography: view on forces in crystals.

Acta Crystallogr B Struct Sci Cryst Eng Mater 2020 Oct 19;76(Pt 5):769-778. Epub 2020 Aug 19.

A.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, 28 Vavilova str., Moscow GSP -1, 119991, Russian Federation.

Quantum theory of atoms in molecules and the orbital-free density functional theory (DFT) are combined in this work to study the spatial distribution of electrostatic and quantum electronic forces acting in stable crystals. The electron distribution is determined by electrostatic electron mutual repulsion corrected for exchange and correlation, their attraction to nuclei and by electron kinetic energy. The latter defines the spread of permissible variations in the electron momentum resulting from the de Broglie relationship and uncertainty principle, as far as the limitations of Pauli principle and the presence of atomic nuclei and other electrons allow. Read More

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October 2020

Acupuncture attenuates the development of diabetic peripheral neuralgia by regulating P2X4 expression and inflammation in rat spinal microglia.

J Physiol Sci 2020 Sep 23;70(1):45. Epub 2020 Sep 23.

School of Integrated Traditional Chinese and Western Medicine, Anhui University of Chinese Medicine, No.1, Qianjiang Road, Hefei, 230012, Anhui, China.

Diabetic peripheral neuropathy (DPN) is a chronic microvascular complication of diabetes. The purpose of this study is to find the underlying mechanism for the effects of acupuncture in DPN rats. Rats were rendered diabetic with a single injection of 35 mg/kg streptozotocin (STZ). Read More

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September 2020

Implementation and sustainment of diverse practices in a large integrated health system: a mixed methods study.

Implement Sci Commun 2020 3;1:61. Epub 2020 Jul 3.

Center for Clinical Management Research, VHA Ann Arbor Healthcare System, 2215 Fuller Rd., 152, Ann Arbor, MI 48105 USA.

Background: One goal of health systems seeking to evolve into learning health systems is to accelerate the implementation and sustainment of evidence-based practices (EBPs). As part of this evolution, the Veterans Health Administration (VHA) developed the Innovation Ecosystem, which includes the Diffusion of Excellence (DoE), a program that identifies and diffuses Gold Status Practices (GSPs) across facilities. The DoE hosts an annual "Shark Tank" competition in which leaders bid on the opportunity to implement a GSP with 6 months of implementation support. Read More

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Anti-Diabetic Effects of Berberis kansuensis Extract on Type 2 Diabetic Rats Revealed by H-NMR-Based Metabolomics and Biochemistry Analysis.

Chem Biodivers 2020 Oct 30;17(10):e2000413. Epub 2020 Sep 30.

School of Ethnic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, P. R. China.

The dried stem bark of Berberis kansuensis C.K.Schneid. Read More

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October 2020

Usability Testing a Potentially Inappropriate Medication Dashboard: A Core Component of the Dashboard Development Process.

Appl Clin Inform 2020 08 12;11(4):528-534. Epub 2020 Aug 12.

Veterans Affairs Greater Los Angeles Medical Center, Geriatric Research Education and Clinical Center, Los Angeles, California, United States.

Background: With the increased usage of dashboard reporting systems to monitor and track patient panels by clinical users, developers must ensure that the information displays they produce are accurate and intuitive. When evaluating usability of a clinical dashboard among potential end users, developers oftentimes rely on methods such as questionnaires as opposed to other, more time-intensive strategies that incorporate direct observation.

Objectives: Prior to release of the potentially inappropriate medication (PIM) clinical dashboard, designed to facilitate completion of a quality improvement project by clinician scholars enrolled in the Veterans Affairs (VA) workforce development Geriatric Scholars Program (GSP), we evaluated the usability of the system. Read More

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The Mental Health Benefits of Physical Activity in Older Adults Survive the COVID-19 Pandemic.

Am J Geriatr Psychiatry 2020 10 30;28(10):1046-1057. Epub 2020 Jun 30.

Department of Kinesiology, University of Maryland (DDC, NAA-N, LSJ, GSP, JW, JCS), College Park, MD; Program in Neuroscience and Cognitive Science, University of Maryland (DDC, LSJ, JCS), College Park, MD. Electronic address:

Objective: To determine the relationship between the amount and intensity of physical activity performed by older adults in North America (United States and Canada) and their depression and anxiety symptoms while currently under social distancing guidelines (SDG) for the COVID-19 pandemic.

Design: Descriptive cross-sectional study.

Setting: Online survey conducted between April 9 and April 30, 2020, during the COVD-19 pandemic. Read More

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October 2020

The Prevalence and Utility of Vascular Surgery Training Programs' and Vascular Societies' Social Media Presence.

Ann Vasc Surg 2020 Nov 4;69:115-124. Epub 2020 Jun 4.

Division of Vascular Surgery, Department of Surgery, The Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address:

Background: There is a paucity of information describing the adoption of social media by the vascular surgery community and social media's effectiveness. We evaluated current trends in social media use by all accredited vascular surgery training programs (VSTPs) in the United States and National and Regional Vascular Societies (NVS) in comparison to hospital/institutions and general surgery programs (GSPs).

Methods: Four major social media platforms (Twitter, Facebook, Instagram, and YouTube) were individually searched for VSTPs, affiliated hospital/institution, affiliated GSP, and NVS profiles (31 societies). Read More

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November 2020

Medical Students' Acquaintance with Core Concepts, Institutions and Guidelines on Good Scientific Practice: A Pre- and Post-questionnaire Survey.

Sci Eng Ethics 2020 06 15;26(3):1827-1845. Epub 2020 Apr 15.

Institute of the History, Philosophy and Ethics of Medicine, Ulm University, Parkstraße 11, 89073, Ulm, Germany.

German medical students are not sufficiently introduced to the ethical principles and pitfalls of scientific work. Therefore, a compulsory course on good scientific practice (GSP) has been developed and implemented into the curriculum of medical students, with the goal to foster scientific integrity and prevent scientific misconduct. Students' knowledge and attitudes towards GSP were evaluated by a pre-post-teaching questionnaire survey (n = 239). Read More

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Effectiveness and cost-effectiveness of group support psychotherapy delivered by trained lay health workers for depression treatment among people with HIV in Uganda: a cluster-randomised trial.

Lancet Glob Health 2020 03 5;8(3):e387-e398. Epub 2020 Feb 5.

MTEK Sciences, Vancouver, BC, Canada; Department of Clinical Epidemiology & Biostatistics, McMaster University, Hamilton, ON, Canada.

Background: WHO recommends the use of psychological interventions as first-line treatment for depression in low-income and middle-income countries. However, evaluations of the effectiveness and cost-effectiveness of such interventions among people with HIV are scarce. Our aim was to establish the effectiveness of group support psychotherapy (GSP) delivered by lay health workers for depression treatment among people living with HIV in a rural area of Uganda on a large scale. Read More

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Grape Seed Polyphenols Ameliorated Dextran Sulfate Sodium-Induced Colitis via Suppression of Inflammation and Apoptosis.

Pharmacology 2020 19;105(1-2):9-18. Epub 2019 Nov 19.

Peking University Institute of Cardiovascular Sciences, Peking University Health Science Center, Peking University, Beijing, China,

Background: Ulcerative colitis (UC) is an inflammatory bowel disease. Its onset is typically gradual, usually followed by periods of spontaneous remission and subsequent relapses. Grape seed polyphenols (GSP), a natural product extracted from grape seeds, have strong anti-inflammatory functions. Read More

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October 2020

Novel deep learning model for more accurate prediction of drug-drug interaction effects.

BMC Bioinformatics 2019 Aug 6;20(1):415. Epub 2019 Aug 6.

Department of Computer Science and Engineering, Incheon National University, Incheon, 22012, South Korea.

Background: Predicting the effect of drug-drug interactions (DDIs) precisely is important for safer and more effective drug co-prescription. Many computational approaches to predict the effect of DDIs have been proposed, with the aim of reducing the effort of identifying these interactions in vivo or in vitro, but room remains for improvement in prediction performance.

Results: In this study, we propose a novel deep learning model to predict the effect of DDIs more accurately. Read More

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[Use of scanning electron microscopy to study Candida albicans biofilms on the surface of base plastics of removable orthopedic constructions.]

Klin Lab Diagn 2019 ;64(5):308-313

FBUN Moscow Research Institute of Epidemiology and Microbiology, named after G.N. Gabrichevsky, Rospotrebnadzor, 125212, Moscow, Russia.

The most common pathology in the clinic of orthopedic dentistry is the presence of partial adentia in patients, manifested in the form of defects of dentition of various localization and length. Removable orthopedic structures in the oral cavity are a potential place for adhesion and colonization of microorganisms. The aim of the research was to study Candida albicans biofilms on the surface of base plastics of removable orthopedic structures using scanning electron microscopy. Read More

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Identification of pyrrolo-pyridine derivatives as novel class of antibacterials.

Mol Divers 2020 Feb 4;24(1):233-239. Epub 2019 Apr 4.

Chemistry Department, Lomonosov Moscow State University, Leninskie Gory, Building 1/3 GSP-1, Moscow, Russian Federation, 119991.

A series of 5-oxo-4H-pyrrolo[3,2-b]pyridine derivatives was identified as novel class of highly potent antibacterial agents during an extensive large-scale high-throughput screening (HTS) program utilizing a unique double-reporter system-pDualrep2. The construction of the reporter system allows us to perform visual inspection of the underlying mechanism of action due to two genes-Katushka2S and RFP-which encode the proteins with different imaging signatures. Antibacterial activity of the compounds was evaluated during the initial HTS round and subsequent rescreen procedure. Read More

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February 2020

Influence of Weight Reduction and Enhanced Protein Intake on Biomarkers of Inflammation in Older Adults with Obesity.

J Nutr Gerontol Geriatr 2019 Jan-Mar;38(1):33-49. Epub 2019 Feb 27.

a Center for the Study of Aging , Duke University Medical Center , Durham , NC , USA.

Both aging and obesity are associated with increased levels of pro-inflammatory metabolites, while weight reduction is associated with improvements in inflammatory status. However, few studies have explored the response of key inflammatory markers to the combined settings of weight reduction in an aging population. There are also few studies that have investigated the potential impact of diet composition on inflammatory marker responses. Read More

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Recruitment and Baseline Characteristics of Participants in the Social, Emotional, and Economic Empowerment Through Knowledge of Group Support Psychotherapy Study (SEEK-GSP): Cluster Randomized Controlled Trial.

JMIR Res Protoc 2019 Jan 3;8(1):e11560. Epub 2019 Jan 3.

Department of Clinical Epidemiology & Biostatistics, McMaster University, Hamilton, ON, Canada.

Background: Psychosocial characteristics, including self-esteem, perceived social support, coping skills, stigma, discrimination, and poverty, are strongly correlated with depression symptoms. However, data on the extent of these correlations among persons living with HIV and the associations between psychosocial characteristics and HIV treatment outcomes are limited in sub-Saharan Africa.

Objective: This paper aims to describe the recruitment process and baseline characteristics associated with depression in a sample of HIV-positive people in a cluster randomized trial of group support psychotherapy (GSP) for depression delivered by trained lay health workers (LHWs). Read More

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January 2019

Good Scientific Practice: Developing a Curriculum for Medical Students in Germany.

Sci Eng Ethics 2020 02 2;26(1):127-139. Epub 2019 Jan 2.

Institute for the History, Philosophy and Ethics of Medicine, Ulm University, Parkstraße 11, 89073, Ulm, Germany.

German medical schools have not yet sufficiently introduced students to the field of good scientific practice (GSP). In order to prevent scientific misconduct and to foster scientific integrity, courses on GSP must be an integral part of the curriculum of medical students. Based on a review of the literature, teaching units and materials for two courses on GSP were developed and tested in a pilot course. Read More

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February 2020

Numerical Investigation of Mixed Convection and Entropy Generation in a Wavy-Walled Cavity Filled with Nanofluid and Involving a Rotating Cylinder.

Entropy (Basel) 2018 Sep 3;20(9). Epub 2018 Sep 3.

School of Mathematical Sciences, Faculty of Science & Technology, Universiti Kebangsaan Malaysia, Bangi Selangor 43600, Malaysia.

This numerical study considers the mixed convection and the inherent entropy generated in Al 2 O 3 -water nanofluid filling a cavity containing a rotating conductive cylinder. The vertical walls of the cavity are wavy and are cooled isothermally. The horizontal walls are thermally insulated, except for a heat source segment located at the bottom wall. Read More

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September 2018

Developing a program to increase geropsychology competencies of Veterans Health Administration (VHA) psychologists.

Gerontol Geriatr Educ 2020 Oct-Dec;41(4):463-479. Epub 2018 Jul 10.

Geriatric Research Education and Clinical Center (GRECC), VHA Greater Los Angeles Health Care System , Los Angeles, CA, USA.

There is an alarming supply and demand gap for geropsychology expertise within the United States. Health policy experts called for increasing geriatric mental health competencies for all mental health providers, including within Veterans Health Administration (VHA), to address this problematic gap. The VHA Geriatrics Scholar Program (GSP) Psychology Track was developed because there were no commercially available trainings in geropsychology for licensed psychologists. Read More

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Enhanced Proton Conductivity and Methanol Permeability Reduction via Sodium Alginate Electrolyte-Sulfonated Graphene Oxide Bio-membrane.

Nanoscale Res Lett 2018 Mar 13;13(1):82. Epub 2018 Mar 13.

Department of Chemical and Process Engineering, Faculty Of Engineering and Built Environment, Universiti Kebangsaan Malaysia (UKM), 43600, Bangi, Selangor, Malaysia.

The high methanol crossover and high cost of Nafion® membrane are the major challenges for direct methanol fuel cell application. With the aim of solving these problems, a non-Nafion polymer electrolyte membrane with low methanol permeability and high proton conductivity based on the sodium alginate (SA) polymer as the matrix and sulfonated graphene oxide (SGO) as an inorganic filler (0.02-0. Read More

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Fabrication and Characterization of New Composite Tio Carbon Nanofiber Anodic Catalyst Support for Direct Methanol Fuel Cell via Electrospinning Method.

Nanoscale Res Lett 2017 Dec 6;12(1):613. Epub 2017 Dec 6.

Fuel Cell Institute, Universiti Kebangsaan Malaysia, 43600, Bangi, Selangor, Malaysia.

Platinum (Pt) is the common catalyst used in a direct methanol fuel cell (DMFC). However, Pt can lead towards catalyst poisoning by carbonaceous species, thus reduces the performance of DMFC. Thus, this study focuses on the fabrication of a new composite TiO carbon nanofiber anodic catalyst support for direct methanol fuel cells (DMFCs) via electrospinning technique. Read More

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December 2017

Enhanced performance of a novel anodic PdAu/VGCNF catalyst for electro-oxidation in a glycerol fuel cell.

Nanoscale Res Lett 2017 Nov 25;12(1):605. Epub 2017 Nov 25.

Fuel Cell Institute, Universiti Kebangsaan Malaysia, UKM, 43600, Bangi, Selangor, Malaysia.

This study presents a novel anodic PdAu/VGCNF catalyst for electro-oxidation in a glycerol fuel cell. The reaction conditions are critical issues affecting the glycerol electro-oxidation performance. This study presents the effects of catalyst loading, temperature, and electrolyte concentration. Read More

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November 2017

Soluble soybean polysaccharides enhance the protective effects of genistein against hepatic injury in high l-carnitine-fed mice.

Food Funct 2017 Dec;8(12):4364-4373

Shaanxi Engineering Laboratory for Food Green Processing and Safety Control, and Key Laboratory of Ministry of Education for Medicinal Resource and Natural Pharmaceutical Chemistry, College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi'an 710062, China.

This study was to develop a novel strategy for the simultaneous consumption of soluble soybean polysaccharides (SSPS) to enhance the absorption of genistein and its protective effects against high l-carnitine-induced hepatic injury in mice. UPLC-qTOP/MS measurements showed that SSPS observably increased the urinary concentration of genistein and its metabolites in mice. The mice fed with 3% l-carnitine water for 12 weeks experienced a disturbance of the hepatic lipid metabolism, oxidative stress and inflammation, which was evidenced by abnormal TC, LDL, RAHFR and MDA levels, unusual AST, ALT, ALP, SOD and GSP-Px activities, and increased IF-1, IF-6 and TNF-α expressions. Read More

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December 2017

Grape-seed Polyphenols Play a Protective Role in Elastase-induced Abdominal Aortic Aneurysm in Mice.

Sci Rep 2017 08 24;7(1):9402. Epub 2017 Aug 24.

Peking University Institute of Cardiovascular Sciences, Peking University Health Science Center, Peking University, Beijing, 100191, China.

Abdominal aortic aneurysm (AAA) is a kind of disease characterized by aortic dilation, whose pathogenesis is linked to inflammation. This study aimed to determine whether grape-seed polyphenols (GSP) has anti-AAA effects and what mechanism is involved, thus to find a way to prevent occurrence and inhibit expansion of small AAA. In our study, AAA was induced by incubating the abdominal aorta of the mice with elastase, and GSP was administrated to the mice by gavage at different doses beginning on the day of the AAA inducement. Read More

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STOP smoking and alcohol drinking before OPeration for bladder cancer (the STOP-OP study), perioperative smoking and alcohol cessation intervention in relation to radical cystectomy: study protocol for a randomised controlled trial.

Trials 2017 07 17;18(1):329. Epub 2017 Jul 17.

Clinical Health Promotion Centre, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospitals, Copenhagen, Denmark.

Background: To evaluate the effect of a smoking-, alcohol- or combined-cessation intervention starting shortly before surgery and lasting 6 weeks on overall complications after radical cystectomy. Secondary objectives are to examine the effect on types and grades of complications, smoking cessation and alcohol cessation, length of hospital stay, health-related quality of life and return to work or habitual level of activity up to 12 months postoperatively.

Methods/design: The study is a multi-institutional randomised clinical trial involving 110 patients with a risky alcohol intake and daily smoking who are scheduled for radical cystectomy. Read More

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