1,441 results match your criteria groups tocopherols

Seafood Intake as a Method of Non-Communicable Diseases (NCD) Prevention in Adults.

Nutrients 2021 Apr 23;13(5). Epub 2021 Apr 23.

Department of Food Industry Processes and Facilities, Koszalin University of Technology, 75-620 Koszalin, Poland.

Seafood (fish in particular) is one of the main food groups in nutrition models with proven health benefits. Seafood has long been considered a very valuable dietary component, mainly due to presence of -3 polyunsaturated fatty acids (-3 PUFA) but it is also an important source of protein (including collagen), anserine, taurine, iodine, selenium, vitamin A, vitamin K, vitamin D, tocopherols, B vitamins and astaxanthin. Considering the beneficial effects of these ingredients on blood pressure, lipid profile and the inflammatory process, seafood should be an essential component of the diet. Read More

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Effect of vitamin E on periodontitis: Evidence and proposed mechanisms of action.

J Oral Biosci 2021 Jun 20;63(2):97-103. Epub 2021 Apr 20.

Department of Craniofacial Diagnostics and Biosciences, Faculty of Dentistry, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur, Malaysia. Electronic address:

Background: Periodontitis is a noncommunicable inflammatory disease of the soft tissue and bone surrounding the teeth in the jaw, which affects susceptible individuals with poor oral hygiene. A growing interest has been seen in the use of dietary supplements and natural products for the treatment and prevention of periodontitis. Vitamin E consists of two major groups, namely tocopherols and tocotrienols, which are botanical lipophilic compounds with excellent anti-inflammatory and antioxidant properties. Read More

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Graphene-Based Sensors for the Detection of Bioactive Compounds: A Review.

Int J Mol Sci 2021 Mar 24;22(7). Epub 2021 Mar 24.

Universidad de Alcalá, Facultad de Ciencias, Departamento de Química Analítica, Química Física e Ingeniería Química, Ctra. Madrid-Barcelona Km. 33.6, 28805 Alcalá de Henares, Madrid, España (Spain).

Over the last years, different nanomaterials have been investigated to design highly selective and sensitive sensors, reaching nano/picomolar concentrations of biomolecules, which is crucial for medical sciences and the healthcare industry in order to assess physiological and metabolic parameters. The discovery of graphene (G) has unexpectedly impulsed research on developing cost-effective electrode materials owed to its unique physical and chemical properties, including high specific surface area, elevated carrier mobility, exceptional electrical and thermal conductivity, strong stiffness and strength combined with flexibility and optical transparency. G and its derivatives, including graphene oxide (GO) and reduced graphene oxide (rGO), are becoming an important class of nanomaterials in the area of optical and electrochemical sensors. Read More

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[Metabolic estimation of efficiency of vitamin and mineral complexes in qualified athletes].

Vopr Pitan 2021;90(1):94-101. Epub 2021 Jan 20.

Bioniq High-Tech Solutions, SE115JH, London, Great Britain.

In professional athletes who adapt to intense physical training and psycho-emotional stress, the formation of oxidative stress is shown. This fact determines the expediency of targeted correction of disorders of the balance of pro- and antioxidant systems in blood and tissues caused by intense physical training. of the work was to study the effect of vitamin-mineral complex on the parameters of oxidative blood metabolism in professional athletes. Read More

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January 2021

Alpha-Tocopherol and Cyanocobalamin Combination Accelerates Peripheral Nerve Healing: An Experimental Animal Study.

Turk Neurosurg 2021 ;31(2):247-253

Metin Sabancı Baltalimanı Bone Diseases Research and Training Hospital, Department of Orthopaedics and Traumatology, Istanbul, Turkey.

Aim: To evaluate the functional and histopathological results of alpha-tocopherol (vitamin E) and vitamin B12 on an experimental rat model of peripheral nerve injury.

Material And Methods: This research included 32 Wistar Hannover rats. The sciatic nerves of the animals were crushed using an aneurysm clamp. Read More

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Beneficial effect of rice bran extract against rotenone-induced experimental Parkinson's disease in rats.

Curr Mol Pharmacol 2021 Jan 25. Epub 2021 Jan 25.

Department of Pharmaceutical Sciences & Technology, Maharaja Ranjit Singh Punjab Technical University, Bathinda, Punjab. India.

Background: Neurodegenerative diseases have become the rising cause of various disabilities worldwide, followed by aging, including Parkinson's disease (PD). Parkinson's disease is a degenerative brain disorder distinguished by growing motor & non-motor failure due to the degeneration of medium-sized spiked neurons in the striatum region. Rotenone is often employed to originate the animal model of PD. Read More

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January 2021

Walnut ( L.) Volatile Compounds Indicate Kernel and Oil Oxidation.

Foods 2021 Feb 4;10(2). Epub 2021 Feb 4.

Department of Food Science and Technology, University of California, Davis, CA 95616, USA.

Kernel oxidation susceptibility and pellicle darkening are among the biggest concerns regarding walnut quality. Monitoring oxidation is crucial to preserve quality from production to consumption. Chemical oxidation parameters (peroxide value and UV absorbances), fatty acid profile, tocopherols, phenols, and volatiles in 'Chandler' and 'Howard' kernels were studied at different time points during 28 weeks of storage to evaluate potential oxidation markers. Read More

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February 2021

Spectroscopic Evidence for Photooxidation of Tocopherols in n-Hexane.

Bogdan Smyk

Molecules 2021 Jan 22;26(3). Epub 2021 Jan 22.

Department of Physics and Biophysics, The Faculty of Food Sciences, University of Warmia and Mazury in Olsztyn, Oczapowskiego 4, 10-719 Olsztyn, Poland.

This paper presents the results of an investigation into the photooxidation of tocopherols (Tocs) dissolved in argonated and non-argonated n-hexane. During irradiation, steady-state absorption and fluorescence spectra as well as lifetimes were measured. In all experiments, the photoreactions were of the first order type. Read More

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January 2021

Effects of daily almond consumption for six months on cognitive measures in healthy middle-aged to older adults: a randomized control trial.

Nutr Neurosci 2021 Jan 15:1-11. Epub 2021 Jan 15.

Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA.

Background: Age-related cognitive decline is a major public health issue. Almonds are rich in nutrients that benefit cognitive function.

Objective: To investigate the impact of almonds on cognition in elderly adults. Read More

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January 2021

Age of Laying Hens Significantly Influences the Content of Nutritionally Vital Lipophilic Compounds in Eggs.

Foods 2020 Dec 23;10(1). Epub 2020 Dec 23.

Animal Resources Research Center, Konkuk University, Seoul 143-701, Korea.

This study aimed to comparatively analyze the carotenoids, tocopherols, fatty acids, and sterols (e.g., cholesterol) in the eggs of laying hens of early (24 weeks), intermediate (42 weeks), and late age (74 weeks), utilizing high-performance liquid chromatography (HPLC), gas chromatography (GC), and GC-mass spectrometry (MS). Read More

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December 2020

Pharmacology and Pharmacokinetics of Vitamin E: Nanoformulations to Enhance Bioavailability.

Int J Nanomedicine 2020 8;15:9961-9974. Epub 2020 Dec 8.

Department of Biochemistry, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia.

Vitamin E belongs to the family of lipid-soluble vitamins and can be divided into two groups, tocopherols and tocotrienols, with four isomers (alpha, beta, gamma and delta). Although vitamin E is widely known as a potent antioxidant, studies have also revealed that vitamin E possesses anti-inflammatory properties. These crucial properties of vitamin E are beneficial in various aspects of health, especially in neuroprotection and cardiovascular, skin and bone health. Read More

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December 2020

Enantioselective Cleavage of Cyclobutanols Through Ir-Catalyzed C-C Bond Activation: Mechanistic and Synthetic Aspects.

Chemistry 2021 Mar 3;27(14):4640-4652. Epub 2021 Feb 3.

Department of Chemistry, University of Cologne, Greinstraße 4, 50939, Köln, Germany.

The Ir-catalyzed conversion of prochiral tert-cyclobutanols to β-methyl-substituted ketones proceeds under comparably mild conditions in toluene (45-110 °C) and is particularly suited for the enantioselective desymmetrization of β-oxy-substituted substrates to give products with a quaternary chirality center with up to 95 % ee using DTBM-SegPhos as a chiral ligand. Deuteration experiments and kinetic isotope effect measurements revealed major mechanistic differences to related Rh -catalyzed transformations. Supported by DFT calculations we propose the initial formation of an Ir hydride intermediate, which then undergoes a β-C elimination (C-C bond activation) prior to reductive C-H elimination. Read More

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Effects of supplementation of DL-methionine on tissue and plasma antioxidant status during heat-induced oxidative stress in broilers.

Poult Sci 2020 Dec 14;99(12):6837-6847. Epub 2020 Sep 14.

University of Giessen, Institute of Animal Nutrition and Nutritional Physiology, Justus-Liebig-University, Giessen, Germany.

Exposure to high ambient temperature has been shown to impair growth performance and to cause oxidative stress in broilers. This study investigated the hypothesis that supplementation with methionine (Met) as DL-Met (DLM) more than the National Research Council recommendations improves growth performance and alleviates oxidative stress in broilers exposed to high ambient temperature. One-day-old male Cobb-500 broilers (n = 68) were allotted to 4 groups and phase-fed 3 basal diets during days 1 to 10, 11 to 21, and 22 to 35. Read More

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December 2020

Buriti pulp oil did not improve high-fat diet-induced metabolic disorders in c57bl/6 mice.

J Anim Physiol Anim Nutr (Berl) 2021 Mar 23;105(2):364-375. Epub 2020 Nov 23.

Protein Purification Laboratory and its Biological Functions (LPPFB), Federal University of Mato Grosso do Sul (UFMS), Campo Grande - MS, Brazil.

Metabolic syndrome (MetS) and obesity are growing in many parts of the world, becoming public health problems. It is proposed that foods with functional properties can assist in the treatment of these diseases. Crude buriti pulp oil (BPO) is a food traditionally consumed by residents in the Pantanal, Cerrado and Brazilian Amazon. Read More

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Evaluation of bioactive compounds in cereals. Study of wheat, barley, oat and selected grain products.

Acta Sci Pol Technol Aliment 2020 Oct-Dec;19(4):405-423

Department of Food Biochemistry and Analysis, Poznań University of Life Sciences, Poland.

Background: One of the requirements for proper nutrition and maintenance of good health is to supply the body, through diet, with an appropriately increased quantity of bioactive compounds. With this in mind, modern milling and baking industries keep introducing new types of products. The use of such additives as wholegrain flours and bran in baked products provided the basis for research in this paper. Read More

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November 2020

Characteristics and Antioxidant Potential of Cold-Pressed Oils-Possible Strategies to Improve Oil Stability.

Foods 2020 Nov 8;9(11). Epub 2020 Nov 8.

Department of Food Science and Dietetics, Wroclaw Medical University, Borowska 211, 50-556 Wroclaw, Poland.

The relations of the antiradical capacity to oxidative stability parameters and the contents of fatty acids, sterols, tocopherols, phenols, flavonoids, chlorophyll, Cu, and Fe were assessed in 33 cold-pressed seed oils: Walnut (7 brands of oils), rosehip (3), camelina (6), milk thistle (5), flax (6), and pumpkin (6). The antiradical capacity of oils depended strongly on tocopherol contents with a synergistic effect with polyphenols. The efficacy of tocopherols in cold-pressed oils was accompanied by a negative correlation of their antioxidant capacity with the peroxide value increase after 3 months of shelf life. Read More

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November 2020

Physicochemical Characteristics, Fatty Acid Profile, Alpha-Tocopherol Content, and Lipid Oxidation of Meat from Ewes Fed Different Levels of Distilled Myrtle Residues.

Molecules 2020 Oct 27;25(21). Epub 2020 Oct 27.

Laboratoire de Productions Animales et Fourragères, INRA-Tunisia, University of Carthage, rue Hédi Karray, Ariana 2049, Tunisia.

The aim of this work was to study the sheep meat physicochemical traits as affected by distilled myrtle residues (MR) supplementation. For this, 27 culled ewes were divided into three groups receiving a ration composed by concentrate and hay for the Control group, concentrate and MR as a total substitute to hay for the Myrt-H group, or hay, less concentrate, and MR as a partial substitute to concentrate for the Myrt-C group. The meat chemical composition, pH, and color parameters were not affected by the MR intake. Read More

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October 2020

The Cryptic Plastid of Defines a New Type of Nonphotosynthetic Plastid Organelle.

mSphere 2020 10 21;5(5). Epub 2020 Oct 21.

Life Science Research Centre, Department of Biology and Ecology, Faculty of Science, University of Ostrava, Ostrava, Czech Republic

Most secondary nonphotosynthetic eukaryotes have retained residual plastids whose physiological role is often still unknown. One such example is , a close nonphotosynthetic relative of harboring a plastid organelle of enigmatic function. By mining transcriptome data from , we finally provide an overview of metabolic processes localized to its elusive plastid. Read More

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October 2020

Chemical Pathology of Homocysteine VIII. Effects of Tocotrienol, Geranylgeraniol, and Squalene on Thioretinaco Ozonide, Mitochondrial Permeability, and Oxidative Phosphorylation in Arteriosclerosis, Cancer, Neurodegeneration and Aging.

Kilmer S McCully

Ann Clin Lab Sci 2020 Sep;50(5):567-577

Pathology and Laboratory Medicine Service, Boston Veterans Affairs Medical Center, and Department of Pathology, Harvard Medical School, Boston, MA, USA

A century ago a fat-soluble vitamin from leafy vegetables, later named vitamin E, was discovered to enhance fertility in animals. Vitamin E consists of 8 isomers of tocopherols and tocotrienols, each containing chromanol groups that confer antioxidant properties and differ only in the 15-carbon saturated phytyl poly-isoprenoid side chain of tocopherols and the 15-carbon unsaturated farnesyl poly-isoprenoid side chain of tocotrienols. Although tocotrienol was first isolated from rubber plants in 1964, its importance in multiple disease processes was not recognized until two decades later, when the cholesterol-lowering and anti-cancer effects were first reported. Read More

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September 2020

Dietary oleuropein extract supplementation and its combination with α-tocopheryl acetate and selenium modifies the free fatty acid profile of pork and improves its stability.

J Sci Food Agric 2021 Apr 16;101(6):2337-2344. Epub 2020 Oct 16.

Incarlopsa, Tarancón, Spain.

Background: Olive-derived antioxidants have been shown to affect the oxidative status of meat and have also been associated with greater consumption of glucose, which might affect glycogen stores and muscle characteristics. This study evaluated the effect of oleuropein extract supplementation (OLE) versus vitamin E + Se (VE), and their combination (VEOLE), in pig diets, on pH, drip loss, the proportion of free fatty acids, and meat stability, and their prediction by blood oxidative status markers.

Results: The drip loss of muscle was lower in antioxidant-supplemented groups when compared with controls. Read More

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Systemic treatment with alpha-tocopherol and/or sodium selenite decreases the progression of experimental periodontitis.

Clin Oral Investig 2021 May 28;25(5):2677-2688. Epub 2020 Sep 28.

Department of Periodontology, Faculty of Dentistry, Başkent University, Ankara, Turkey.

Objective: To investigate the effects of sodium selenite (Se) and/or α-tocopherol (αT) applications on the alveolar bone loss (ABL), the number of gingival collagen fibers, inducible nitric oxide synthase (iNOS)+ and CD95+ cell numbers, and serum cytokine concentrations in experimental periodontitis in rats.

Materials And Methods: Forty Sprague Dawley rats were divided into four groups of ten as follows: group A: Se group, group B: αT group, group C: Se and αT combined group, and group D: control group (intraperitoneal (IP) saline injection applied). Using the image analysis method in the connective tissue under the connective epithelium, the numbers of iNOS, CD95 positive cells, and collagen fibers were counted. Read More

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Buckwheat Secondary Metabolites: Potential Antifungal Agents.

J Agric Food Chem 2020 Oct 8;68(42):11631-11643. Epub 2020 Oct 8.

Department of Dairy, Fat and Cosmetics, Faculty of Food and Biochemical Technology, University of Chemistry and Technology Prague, Technická 5, 166 28 Prague, Czech Republic.

Research groups have put significant emphasis on the evaluation of nutritional, health-promoting, and other biological activities of secondary metabolites from buckwheat. Among these phytochemicals, phenolic and lipophilic antioxidants, particularly, phenolic acids, flavonoids, and tocopherols, have been the focus of the latest studies since antioxidant activity has recently been associated with the possibility of inhibiting fungal growth and mycotoxin biosynthesis. The mycotoxin contamination of cereal and pseudocereal grains caused primarily by , , and species poses a significant hazard to human health. Read More

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October 2020

Brain α-Tocopherol Concentration and Stereoisomer Profile Alter Hippocampal Gene Expression in Weanling Mice.

J Nutr 2020 12;150(12):3075-3085

Center for Nutrition, Learning and Memory, University of Illinois, Urbana-Champaign, Illinois, USA.

Background: Alpha-tocopherol (αT), the bioactive constituent of vitamin E, is essential for fertility and neurological development. Synthetic αT (8 stereoisomers; all rac-αT) is added to infant formula at higher concentrations than natural αT (RRR-αT only) to adjust for bio-potency differences, but its effects on brain development are poorly understood.

Objectives: The objective was to determine the impact of bio-potency-adjusted dietary all rac-αT versus RRR-αT, fed to dams, on the hippocampal gene expression in weanling mice. Read More

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December 2020

Pyrethroid-Induced Organ Toxicity and Anti-Oxidant-Supplemented Amelioration of Toxicity and Organ Damage: The Protective Roles of Ascorbic Acid and α-Tocopherol.

Int J Environ Res Public Health 2020 08 25;17(17). Epub 2020 Aug 25.

Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, Qassim University, Qassim 51452, Saudi Arabia.

The pyrethroid toxicants, fatal at high doses, are found as remnants of crop pesticides and ingredients of commercially available insecticides. The toxic effects of high-content insecticidal pyrethroid formulations are available in 0.05 g, 1. Read More

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Corneal UV Protective Effects of a Topical Antioxidant Formulation: A Pilot Study on In Vivo Rabbits.

Int J Mol Sci 2020 Jul 30;21(15). Epub 2020 Jul 30.

Department of Medicine and Health Science "V. Tiberio", University of Molise, 86100 Campobasso, Italy.

This study aimed to evaluate the protective effect of a topical antioxidant and ultraviolet (UV) shielding action formulation containing riboflavin and D-α-tocopherol polyethylene glycol succinate (TPGS) vitamin E against corneal UV-induced damage in vivo rabbit eyes. In vivo experiments were performed using male albino rabbits, which were divided into four groups. The control group (CG) did not receive any UV irradiation; the first group (IG) was irradiated with a UV-B-UV-A lamp for 30 min; the second (G30) and third (G60) groups received UV irradiation for 30 and 60 min, respectively, and were topically treated with one drop of the antioxidant and shielding formulation every 15 min, starting one hour before irradiation, until the end of UV exposure. Read More

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Physico-chemical characterization of Cornus kousa Burg. fruit: determining optimal maturity for fresh consumption.

J Sci Food Agric 2021 Jan 10;101(2):778-785. Epub 2020 Aug 10.

Department of Agronomy, Biotechnical Faculty, University of Ljubljana, Ljubljana, Slovenia.

Background: Japanese dogwood (Cornus kousa Burg.) is a popular ornamental plant which develops edible compound fruit utilized in traditional Asian medicine. Previous compositional studies have focused on a small fraction of secondary metabolites at a single maturity stage. Read More

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January 2021

Is α-Tocopherol or Sodium Ascorbate Effective as Antioxidant on Fracture Resistance of Bleached Teeth?

J Contemp Dent Pract 2020 May 1;21(5):481-485. Epub 2020 May 1.

Department of Restorative Dentistry, Araraquara Dental School, UNESP-Univ Estadual Paulista, Araraquara, São Paulo, Brazil, Phone: +55 1633016396, e-mail:

Aim: To evaluate the effect of two antioxidant formulations (sodium ascorbate and α-tocopherol) on fracture resistance of endodontically treated teeth.

Materials And Methods: Sixty human premolars were endodontically treated and divided into six groups ( = 10): G1 (negative control)-unbleached and restored with composite resin; G2 (positive control)-bleached in three sessions, using hydrogen peroxide (15 HO) plus titanium dioxide (TiO) nanoparticles, photoactivated by LED laser system and restored with composite resin; G3-bleaching similar to G2, after the use of 10% sodium ascorbate gel for 24 hours and restored with composite resin; G4-similar to G3, but with the use of 10% sodium ascorbate solution and restored with composite resin; G5 and G6-similar to G3, but with the use of 10% α-tocopherol in alcohol or carbopol, respectively, and was also restored. A mechanical fracture resistance test was performed and the Kruskal-Wallis test was used to evaluate the results ( = 0. Read More

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Tocotrienols Influence Body Weight Gain and Brain Protein Expression in Long-Term High-Fat Diet-Treated Mice.

Int J Mol Sci 2020 Jun 25;21(12). Epub 2020 Jun 25.

Molecular Cell Biology Laboratory, Department of Functional Control Systems, Graduate School of Engineering and Science, Shibaura Institute of Technology, Fukasaku 307, Minuma-ku, Saitama 337-8570, Japan.

Obesity induces serious diseases such as diabetes and cardiovascular disease. It has been reported that obesity increases the risk of cognitive dysfunction. Cognitive dysfunction is a characteristic symptom of Alzheimer's and Parkinson's diseases. Read More

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Infant Rhesus Macaque Brain α-Tocopherol Stereoisomer Profile Is Differentially Impacted by the Source of α-Tocopherol in Infant Formula.

J Nutr 2020 09;150(9):2305-2313

Division of Nutritional Sciences, University of Illinois at Urbana-Champaign, IL.

Background: α-Tocopherol (αT) in its natural form [2'R, 4'R, 8'R αT (RRR-αT)] is more bioactive than synthetic α-tocopherol (all rac-αT). All rac-αT is widely used in infant formulas, but its accretion in formula-fed infant brain is unknown.

Objective: We sought to compare αT and stereoisomer status in infant rhesus macaques (Macaca mulatta) fed infant formula (RRR-αT or all rac-αT) with a reference group fed a mixed diet of breast milk and maternal diet. Read More

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September 2020

The Relationship between Serum Vitamin E Level and Risk Factors for Arteriosclerosis in Japanese Postmenopausal Women.

J Nutr Sci Vitaminol (Tokyo) 2020 ;66(3):213-218

Department of Clinical Nutrition, Graduate School of Comprehensive Rehabilitation, Osaka Prefecture University.

Since vitamin E is one of the most potent antioxidant and anti-inflammatory agents, vitamin E can play a role against arteriosclerosis through various actions. Then, we have studied the relationship between serum vitamin E status and risk factors for arteriosclerosis in Japanese postmenopausal women. One hundred and seven subjects (70. Read More

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