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Clinical features and outcomes of critically ill patients with Elizabethkingia meningoseptica: an emerging pathogen.

Acute Crit Care 2021 Jul 26. Epub 2021 Jul 26.

Section of Infectious Diseases, Department of Medicine, Aga Khan University, Karachi, Pakistan.

Background: Elizabethkingia meningoseptica, formerly known as Chryseobacterium meningosepticum, is a non-motile, non-fastidious, catalase and oxidase-positive, aerobic, glucose-non-fermentative, Gram-negative bacillus that was first defined by Elizabeth O. King in 1959. It has emerged as an opportunistic pathogen that has infected patients in extreme age groups and immunocompromised individuals, especially in intensive care settings. Read More

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Altered central and peripheral hemodynamics during rhythmic handgrip exercise in young adults with SARS-CoV-2.

Exp Physiol 2021 Jul 26. Epub 2021 Jul 26.

Department of Health & Exercise Science, Appalachian State University, Boone, NC.

New Findings: What is the central question of this study? This study sought to investigate whether central and peripheral hemodynamics during handgrip exercise were different in young adults 3-4 weeks following infection with of SARS-CoV-2 compared with young healthy adults. What is the main finding and its importance? The main findings are that exercising heart rate was higher while brachial artery blood flow and vascular conductance were lower in the SARS-CoV-2 compared with the control group. These findings provide evidence for peripheral impairments to exercise among adults with SARS-CoV-2, which may contribute to exercise limitations. Read More

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Descemet Membrane Endothelial Keratoplasty (DMEK) in Previously Vitrectomized Eyes: Complications and Clinical Outcomes.

Klin Monbl Augenheilkd 2021 Jul 26. Epub 2021 Jul 26.

Klinik für Augenheilkunde, Universitätsklinikum des Saarlandes und Medizinische Fakultät der Universität des Saarlandes, Homburg, Germany.

Purpose: To evaluate the results and complications of Descemet membrane endothelial keratoplasty (DMEK) in previously vitrectomized eyes.

Design: Retrospective study of 35 eyes that had undergone DMEK, due to Fuchs endothelial corneal dystrophy (FECD), at our department with a follow-up after 6 months postoperatively. We compared the intraoperative procedure, complications, and results of DMEK between 14 previously vitrectomized pseudophakic eyes (group 1) and a control group of 21 pseudophakic non-vitrectomized eyes (group 2). Read More

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Effects of Age on Match-related Acceleration and Deceleration Efforts in Elite Soccer Players.

Int J Sports Med 2021 Jul 26. Epub 2021 Jul 26.

Faculty of Education and Sport Sciences, University of Vigo, Pontevedra, Spain.

The aim of this study was to examine the effects of chronological age on acceleration and deceleration match performance in professional soccer players. A total of 5317 individual match observations were collected on 420 professional players competing in the Spanish during the 2018-2019 season, using a multiple-camera computerised tracking system (TRACAB; ChyronHego, Melville, NY, USA). Players were classified using a -means cluster analysis into four different age groups: 17-23 years, 24-27 years, 28-30 years, and 31-38 years. Read More

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Longer Axial Length Potentiates Relationship of Intraocular Pressure and Peripapillary Vessel Density in Glaucoma Patients.

Invest Ophthalmol Vis Sci 2021 Jul;62(9):37

USC Roski Eye Institute, Keck School of Medicine of University of Southern California, Los Angeles, California, United States.

Purpose: The purpose of this study was to investigate how axial length (AL) changes the relationship of intraocular pressure (IOP) with peripapillary vessel density (pVD) in glaucoma versus non-glaucomatous eyes.

Methods: A population-based, cross-sectional study of 2127 African Americans aged 40 years and older in Inglewood, California, were imaged with 6 × 6-mm optic disc optical coherence tomography angiography scans. There were 1028 healthy subjects (1539 eyes) and 65 subjects with glaucoma (86 eyes) who met inclusion criteria. Read More

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Associations among Audiometric, Doppler Hydroacoustic, and Subjective Outcomes of Venous Pulsatile Tinnitus.

ORL J Otorhinolaryngol Relat Spec 2021 Jul 26:1-10. Epub 2021 Jul 26.

Department of Otology and Skull Base Surgery, Eye Ear Nose and Throat Hospital, Fudan University, Shanghai, China.

Objective: Venous pulsatile tinnitus (PT) has received increasing attention recently. As analyses of psychophysical and neuropsychological dimensions of venous PT are lacking, this study aimed to quantitatively and qualitatively investigate the correlation among audiometric, hydroacoustic, and subjective outcomes in patients with PT.

Methods: Fifty-five venous PT patients, with or without sigmoid sinus wall anomalies (SSWAs), were subdivided into SSWAs (n = 30) and non-SSWAs (n = 25) groups. Read More

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Lifestyle Intervention for Overweight/Obese Pregnant Women with Polycystic Ovarian Syndrome: Lessons and Challenges.

Obes Facts 2021 Jul 26:1-10. Epub 2021 Jul 26.

Division of Endocrinology and Metabolism, Department of Obstetrics, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China.

Introduction And Objective: Polycystic ovary syndrome (PCOS) is the most common reproductive disorder in women of reproductive age, and overweight and obesity are highly prevalent in women with PCOS. This study aims to explore whether lifestyle intervention can improve gestational weight gain (GWG), glucolipid metabolism, and perinatal outcomes in overweight/obese pregnant women with PCOS.

Methods: This study is a randomized controlled trial that included overweight and obese pregnant women with PCOS who met the inclusion criteria of 8-12 gestational weeks. Read More

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Insight into the role of extracellular polymeric substances in denitrifying biofilms under nitrobenzene exposure.

Ecotoxicol Environ Saf 2021 Jul 23;222:112539. Epub 2021 Jul 23.

Department of Environmental Engineering, Peking University, Beijing 100871, China. Electronic address:

Denitrifying biofilm promises to be very useful for remediation of nitro-aromatic compounds (NACs) and nitrates in wastewater. Little is known about the role of extracellular polymeric substances (EPS) in nitrobenzene (NB, a typical NAC) remediation, despite the indispensability of EPS for biofilm formation. Herein, the significance of the mechanistic role of EPS in the response of denitrifying biofilms to various levels of NB was investigated. Read More

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Probing Si-O connectivities and proximities by solid-state NMR.

J Magn Reson 2021 Jul 2;330:107029. Epub 2021 Jul 2.

Univ. Lille, CNRS, Centrale Lille, Univ. Artois, UMR 8181-UCCS- Unité de Catalyse et Chimie du Solide, F-59000 Lille, France; Institut Universitaire de France, France.

The measurement of dipolar and J- couplings between Si and O isotopes is challenging owing to (i) the low abundance of both isotopes and (ii) their close Larmor frequencies, which only differ by 19%. These issues are circumvented here by the use of isotopic enrichment and dedicated triple-resonance magic-angle spinning NMR probe. The surface of Si-enriched silica was labelled with O isotope and heated at 80 and 200 °C. Read More

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Immediate Effects of Arm Reaching Training in Standing on Postural Control Differ between Right and Left Stroke Individuals.

J Stroke Cerebrovasc Dis 2021 Jul 23;30(9):105984. Epub 2021 Jul 23.

University of City of São Paulo (UNICID), Brazil. Electronic address:

Background: Arm reaching training in standing for several weeks affects the postural control of individuals recovering from cerebrovascular accident (CVA). Whether these effects differ with the side of the brain lesion are unknown.

Objectives: To examine the immediate effects of a training session of arm reaching movements on the balance and trunk motion of individuals who suffered a right or left CVA. Read More

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Enhanced remediation of heavy metals contaminated soils with EK-PRB using β-CD/hydrothermal biochar by waste cotton as reactive barrier.

Chemosphere 2021 Jul 7;286(Pt 1):131470. Epub 2021 Jul 7.

College of Environmental Science and Engineering, State Environmental Protection Engineering Center for Pollution Treatment and Control in Textile Industry, Donghua University, Shanghai, 201620, China.

Heavy metals in the soil are major global environmental problems. Waste cotton was used to synthesize a novel β-CD/hydrothermal biochar (KCB), which is a low-cost and environment-friendly adsorbent for heavy metal soil remediation. KCB were used as reactive materials of electrokinetic-permeable reactive barrier (EK-PRB) to explore the removal characteristics of heavy metals. Read More

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Methods of synthesis, characteristics, and environmental applications of MXene: A comprehensive review.

Chemosphere 2021 Jul 20;286(Pt 1):131607. Epub 2021 Jul 20.

Department of Chemical Engineering, Annamalai University, Tamilnadu, India.

MXene, comprised of two-dimensional transition metal carbides/nitride, has emerged as a novel material suitable for environmental remediation of toxic compounds. Due to their inherent and superior physical and chemical properties, MXene is employed in separation techniques like photocatalysis, adsorption, and membrane separation. MXene is equipped with a highly hydrophilic surface, ion exchange property, and robust surface functional groups. Read More

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Perturbation of miR-146b and relevant inflammatory elements in esophageal carcinoma patients supports an immune downregulatory mechanism.

Pathol Res Pract 2021 Jul 20;225:153560. Epub 2021 Jul 20.

Women's Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address:

Background: Esophageal Cancer is known as one of the deadliest cancers worldwide with the squamous cell carcinoma (ESCC) being the predominant subtype. There is a growing body of evidence linking the dysregulated microRNA (miRNA) pathway of immune cells to the progression of several tumors. In a previous study, we investigated molecular alterations pertaining to miR-146a and some components of NF-kB signaling pathway and proposed a possible immune downregulatory mechanism in peripheral blood mononuclear cells (PBMCs) of ESCC patients. Read More

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Application of Machine Learning for eutrophication analysis and algal bloom prediction in an urban river: A 10-year study of the Han River, South Korea.

Sci Total Environ 2021 Jul 17;797:149040. Epub 2021 Jul 17.

Department of Environment and Energy, Sejong University, Seoul 05006, South Korea. Electronic address:

The increasing release of nutrients to aquatic environments has led to great concern regarding eutrophication and the risk of unwanted algal blooms. Based on observational data of 20 water quality parameters measured on a monthly basis at 40 stations from 2011 to 2020, this study applied different Machine Learning (ML) algorithms to suggest the best option for algal bloom prediction in the Han River, a large river in South Korea. Eight different ML algorithms were categorized into several groups of statistical learning, regression family, and deep learning, and were then compared for their suitability to predict the chlorophyll-derived trophic index (TSI-Chla). Read More

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Effects of polystyrene and triphenyl phosphate on growth, photosynthesis and oxidative stress of Chaetoceros meülleri.

Sci Total Environ 2021 Jul 21;797:149180. Epub 2021 Jul 21.

Institute of Marine Science and Technology, Shandong University, Qingdao 266237, PR China. Electronic address:

The toxicity of microplastics to marine organisms has attracted much attention; however, studies of their effects on marine microalgae remain limited. Here, the effects of the single and combined toxicity of polystyrene (PS) and triphenyl phosphate (TPhP) on the cell growth, photosynthesis, and oxidative stress of Chaetoceros meülleri were investigated. PS inhibited growth of the algae cells and caused a dose-dependent effect on oxidative stress. Read More

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Shotgun mass spectrometry-based lipid profiling identifies and distinguishes between chronic inflammatory diseases.

EBioMedicine 2021 Jul 23;70:103504. Epub 2021 Jul 23.

iNOVA4Health, CEDOC, NOVA Medical School, NMS, Universidade Nova de Lisboa, 1169-056 Lisboa, Portugal. Electronic address:

Background: Localized stress and cell death in chronic inflammatory diseases may release tissue-specific lipids into the circulation causing the blood plasma lipidome to reflect the type of inflammation. However, deep lipid profiles of major chronic inflammatory diseases have not been compared.

Methods: Plasma lipidomes of patients suffering from two etiologically distinct chronic inflammatory diseases, atherosclerosis-related vascular disease, including cardiovascular (CVD) and ischemic stroke (IS), and systemic lupus erythematosus (SLE), were screened by a top-down shotgun mass spectrometry-based analysis without liquid chromatographic separation and compared to each other and to age-matched controls. Read More

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Effect of supplemental acid-etching on the early stages of osseointegration: A preclinical model.

J Mech Behav Biomed Mater 2021 Jul 13;122:104682. Epub 2021 Jul 13.

Department of Biomaterials, New York University College of Dentistry, New York, NY, USA; Department of Biomedical Engineering, New York University Tandon School of Engineering, Brooklyn, NY, USA. Electronic address:

Purpose: To evaluate the effect of two surface modifications on early osseointegration parameters of conical implants in a translational pre-clinical model.

Materials And Methods: Conical implants with progressive trapezoidal threads and healing chambers were evaluated consisting of two different surface conditions: 1) Implacil surface (IMP Sur), and 2) Implacil surface + Supplemental Acid-etching (IMP Sur + AE). Surface characterization comprised of the evaluation of roughness parameters (S, S and S), surface energy and contact angle. Read More

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Improving the post-thaw quality of rooster semen using the extender supplemented with resveratrol.

Poult Sci 2021 May 27;100(9):101290. Epub 2021 May 27.

Department of Embryology at Reproductive Biomedicine Research Center, Royan Institute Reproductive Biomedicine, ACECR, Tehran, Iran.

Avian spermatozoa are highly susceptible to reactive oxygen species (ROS) produced during the cryopreservation. The aim of the current study was to investigate the antioxidant effects of resveratrol (RSV) during rooster semen cryopreservation. Changes in expression of AMP-activated protein kinase as a possible mechanism behind the beneficial effects of resveratrol were also evaluated. Read More

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Examining the novel use of continuous compression implants in clavicle reconstruction: A biomechanical study.

Clin Biomech (Bristol, Avon) 2021 Jul 21;88:105437. Epub 2021 Jul 21.

University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

Background: Current implants for clavicle fractures are known to cause poor cosmesis and irritation, which may require implant removal. Low-profile shape-memory staples provide an attractive alternative, but their biomechanical utility in clavicle reconstruction is unknown. We hypothesized that shape-memory reconstructions would be more compliant compared to traditional constructs but would also outperform conventional plates during cyclic loading to failure. Read More

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Highly selective hydrogenation of phenol to cyclohexanone over a Pd-loaded N-doped carbon catalyst derived from chitosan.

J Colloid Interface Sci 2021 Jul 19;605:82-90. Epub 2021 Jul 19.

Joint Institute of Biological Science, Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37830, USA.

A highly stable Pd-loaded N-doped carbon catalyst (ACN) for phenol hydrogenation was prepared from chitosan by hydrothermal carbonization. ACN does not require a reduction step before catalytic use due to the Pd in the as-prepared catalyst mainly exists in the form of Pd (80%). The carbon support involves N-containing groups such as pyridinic nitrogen and pyrrolic nitrogen, which could provide basic sites to adsorb phenol effectively. Read More

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Spatial sonification of letters on tablets to stimulate literacy skills and handwriting in 5 y-o children: A pilot study.

Hum Mov Sci 2021 Jul 23;79:102844. Epub 2021 Jul 23.

Laboratoire d'Etude des Mécanismes Cognitifs (EA 3082), MSH LSE USR CNRS 2005, Université Lyon2, France; LabEx Cortex ANR-11-LABX-0042, Université de Lyon, France.

We evaluate the effects of multisensory training on letters, including sonification of graphic symbols. We used "spatial sonification" where letter handwriting movements recorded in a two dimensional plan, vertical and horizontal, are systematically assigned to two acoustic features, spectral composition for the horizontal axis and frequency for the vertical axis. Forty-six kindergarten children were recruited. Read More

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The influence of the built environment in enacting a household model of residential aged care for people living with a mental health condition: A qualitative post-occupancy evaluation.

Health Place 2021 Jul 23;71:102624. Epub 2021 Jul 23.

Centre for Health Services Management, School of Public Health, Faculty of Health, University of Technology Sydney, Harris St, Ultimo, NSW 2007, Australia. Electronic address:

This study undertakes a spatial analysis of an Australian aged care setting where residents receive person-centred support in a specially-designed home-like environment. Focus groups were conducted with staff to explore the impact of the built environment in a new residential aged care setting that has implemented a Household Model of care for people living with mental health conditions. Drawing on Actor-Network Theory and proxemics, we mapped how the built environment supports improved behaviours and care practices in four areas: food preparation and dining, sleep and self-care, site layout, and relationships. Read More

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The effects of Zinc-Methionine on glucose metabolism and insulin resistance during late pregnancy in ewes.

Domest Anim Endocrinol 2021 Jul 1;77:106647. Epub 2021 Jul 1.

Department of Internal Medicine and Clinical Pathology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.

This study investigated the effects of dietary supplements of Zinc-Methionine (Zn-Met) on the zinc concentration of the blood and indices such as insulin resistance and glucose tolerance in late-pregnancy ewes to provide a practical solution to prevent metabolic diseases associated with energy status. In this research, 18 Makouei pregnant ewes were selected and randomized into 3 experimental groups: Group 1: Basal diet containing 10.3 mg Zn/kgDM and no zinc supplementation = CTR (Control); Group 2: Basal diet supplemented with low-dose zinc equivalent to the pregnancy requirements (30 mg Zn/kgDM) = LZN; Group 3: Basal diet supplemented with high-dose zinc (300 mg Zn/kgDM) = HZN. Read More

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What remains on the beach after tourists leave? The case of Abaís beach (Sergipe, Brazil).

Mar Pollut Bull 2021 Jul 23;171:112700. Epub 2021 Jul 23.

Instituto de Biologia, Universidade Federal de Uberlândia, Campus Umuarama, rua Ceará s/n Bloco 2D, sala 28, CEP 38405-302 Uberlândia, Minas Gerais, Brazil. Electronic address:

The study evaluated the characteristics of marine litter disposed of by tourists on the Abaís beach (state of Sergipe, Brazil), during the dry (December/2017, January/2018, and February/2018) and rainy (May/2018, June/2018, and July/2018) months. Litter was collected on a Sunday of each month after the tourists left. The values of abundance (9. Read More

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The influence of developmental noise exposure on the temporal processing of acoustical signals in the auditory cortex of rats.

Hear Res 2021 Jul 9;409:108306. Epub 2021 Jul 9.

Department of Auditory Neuroscience, Institute of Experimental Medicine, Czech Academy of Sciences, Vídeňská 1083, 14220 Prague 4, Czech Republic.

Previous experiments have acknowledged that inappropriate or missing auditory inputs during the critical period of development cause permanent changes of the structure and function of the auditory system (Bures et al., 2017). We explore in this study how developmental noise exposure influences the coding of temporally structured stimuli in the neurons of the primary auditory cortex (AC) in Long Evans rats. Read More

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Long-term analgesic and opioid prescription after surgery under general or neuraxial anesthesia: A retrospective nationwide sampling study.

J Clin Anesth 2021 Jul 23;75:110438. Epub 2021 Jul 23.

Department of Anesthesiology, Chi Mei Medical Center, 901 Zhonghua Road, Yongkang District, Tainan, Taiwan. Electronic address:

Study Objective: Chronic postsurgical pain (CPSP) is a common and underreported but significant outcome following surgery. Pharmacological treatment with analgesics, including non-opioids and opioids, is frequently used. It has been debated whether neuraxial anesthesia can reduce persistent analgesic use. Read More

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Electronic nicotine delivery systems (ENDS) cue reactivity in dual users: A combined analysis.

Drug Alcohol Depend 2021 Jul 21;227:108909. Epub 2021 Jul 21.

The University of Illinois at Chicago, Department of Visual Sciences and Opthalmology, Chicago, IL, 60607, United States.

Background: Cigarette smokers report increases in smoking urge in response to exposure to electronic nicotine delivery systems (ENDS) and dual users, i.e. smokers who also vape ENDS, may exhibit greater cue reactivity than exclusive smokers. Read More

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Development of a natamycin-based non-migratory antimicrobial active packaging for extending shelf-life of yogurt drink (Doogh).

Food Chem 2021 Jul 16;366:130606. Epub 2021 Jul 16.

Department of Food Science and Technology, School of Agriculture, Shiraz University, Shiraz 71441-65186, Iran; Department of Biological Sciences, School of Natural Science, University of Limerick, Limerick, Ireland. Electronic address:

A natamycin-based non-migratory antimicrobial packaging for extending shelf-life of yogurt drink (Doogh) was developed. Firstly, the surface of low-density polyethylene film (LDPE) was modified with acrylic acid at different times of UV exposure (0-10 min) to produce carboxylic functional groups. Then, natamycin was applied to the UV-treated films to bind covalently with the pendent functional groups. Read More

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Sediment quality assessment combining chemical and biological (non)target analysis.

Aquat Toxicol 2021 Jun 8;238:105883. Epub 2021 Jun 8.

Risk Assessment Research Center, Korea Institute of Ocean Science and Technology, Geoje 53201, Republic of Korea; Department of Ocean Science, Korea University of Science and Technology, Daejeon 34113, Republic of Korea. Electronic address:

Aquatic sediments act as a storage for diverse mixtures of organic and inorganic contaminants. Nevertheless, most evaluations of contaminated sediments have been limited to the assessment of concentrations of target compounds and lethal effects on some test species. To identify the organic contaminants causing sub-lethal effects of contaminated sediment, this study combined chemical and biological (non)target analysis involving comprehensive two-dimensional gas chromatography coupled with a time-of-flight Mass Spectrometer (GCxGC/ToF-MS) analysis, embryonic malformation and high-throughput sequencing (RNA-seq) analysis on developing flounder. Read More

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