16,604 results match your criteria groups n = 50

Trophic differences regulate grassland food webs: herbivores track food quality and predators select for habitat volume.

Ecology 2021 Jun 24:e03453. Epub 2021 Jun 24.

Geographical Ecology Group, Department of Biology, University of Oklahoma, Norman, OK, 73019, USA.

The impacts of altered biogeochemical cycles on ecological systems are likely to vary with trophic level. Predicting how these changes will affect ecological food webs is further complicated by human activities which are simultaneously altering the availability of macronutrients like nitrogen (N) and phosphorus (P), and micronutrients such as sodium (Na). Here we contrast three hypotheses that predict how increasing nutrient availability will shape grassland food webs. Read More

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Biofunctional significance of multi-herbal combination against paracetamol-induced hepatotoxicity in Wistar rats.

Environ Sci Pollut Res Int 2021 Jun 24. Epub 2021 Jun 24.

Department of Botanical & Environmental Sciences, Guru Nanak Dev University, Amritsar, Punjab, 143005, India.

A multi-herbal combination (MHC) of five herbs, namely Punica granatum L., Putranjiva roxburghii Wall., Swertia chirata Buch. Read More

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Changes in Biomarkers of Cigarette Smoke Exposure After 6 Days of Switching Exclusively or Partially to Use of the JUUL System with Two Nicotine Concentrations: A Randomized Controlled Confinement Study in Adult Smokers.

Nicotine Tob Res 2021 Jun 23. Epub 2021 Jun 23.

Pinney Associates, Inc., Bethesda MD.

Introduction: Evidence suggests that cigarette smokers who switch to electronic nicotine delivery systems (ENDS) reduce their exposure to harmful toxicants and carcinogens. It is unclear if dual use is associated with decreases in exposure to toxicants.

Methods: This parallel-group confinement study assessed changes in biomarkers of exposure (BOEs) over six days among healthy adult smokers who were randomized into 1 of 11 study groups: eight JUUL-brand System (JUUL) groups (4 JUUL flavors [Virginia Tobacco, Menthol, Mint, Mango] × 2 nicotine concentrations [5. Read More

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Socioeconomic Status and Survival in Nasopharyngeal Carcinoma: A Population-Based Study.

Laryngoscope 2021 Jun 23. Epub 2021 Jun 23.

Department of Otolaryngology-Head and Neck Surgery, Tulane University School of Medicine, New Orleans, Louisiana, U.S.A.

Objectives/hypothesis: To evaluate survival for nasopharyngeal carcinoma in relation to socioeconomic status.

Study Design: Retrospective cohort study using the Surveillance, Epidemiology, and End Results (SEER) Census Tract-level Socioeconomic Status Database (2000-2016).

Methods: Patients with nasopharyngeal carcinoma diagnosed between 2000 and 2016 were identified. Read More

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Changes in the Hepatitis B Surface Antigen Level According to the HBeAg Status and Drug Used in Long-term Nucleos(t)ide Analog-treated Chronic Hepatitis B Patients.

Korean J Gastroenterol 2021 Jun;77(6):285-293

Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.

Backgrounds/aims: The HBsAg levels have been used to monitor the chronic hepatitis B (CHB) treatment response to antiviral therapy. On the other hand, it is unclear if the HBsAg quantification levels at each treatment point differ according to the HBeAg status and drug in CHB patients. This study compared the changes in HBsAg in CHB patients according to the HBeAg status and treatment drugs. Read More

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Evidence of Tinnitus Development Due to Stress: An Experimental Study in Rats.

Laryngoscope 2021 Jun 22. Epub 2021 Jun 22.

Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Objectives/hypothesis: Tinnitus can develop due to, or be aggravated by, stress in a rat model. To investigate stress as a possible causal factor in the development of tinnitus, we designed an animal study that included tinnitus behavior and excitatory/inhibitory neurotransmitter expression after noise exposure as well as restraint stress.

Study Design: An experimental animal study. Read More

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The efficacy of adjuvant chemotherapy with capecitabine and cisplatin after surgery in locally advanced esophageal squamous cell carcinoma: a multicenter randomized phase III trial.

Dis Esophagus 2021 Jun 21. Epub 2021 Jun 21.

Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.

There is limited evidence for the effectiveness of adjuvant chemotherapy in esophageal squamous cell carcinoma (ESCC). This study aimed to assess whether adjuvant capecitabine and cisplatin improve survival compared to surgery alone among patients with locally advanced ESCC. This is a multicenter randomized controlled trial. Read More

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Health technology assessment through the six sigma approach in abdominoplasty: Scalpel vs electrosurgery.

Med Eng Phys 2021 Jul 28;93:27-34. Epub 2021 May 28.

Department of Public Health, University Hospital of Naples "Federico II", Naples, Italy.

Abdominoplasty is a surgical procedure conducted to reduce excess abdominal skin and fat and improve body contouring. Despite being commonly performed, it is associated with a risk of complications such as infection, seroma, haematoma and wound dehiscence. To reduce the incidence of complications, different methods are used to create the abdominal flap, i. Read More

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The effect of a 24-week training focused on activities of daily living, muscle strengthening, and stability in idiopathic inflammatory myopathies: a monocentric controlled study with follow-up.

Arthritis Res Ther 2021 Jun 21;23(1):173. Epub 2021 Jun 21.

Institute of Rheumatology, Na Slupi 4, 128 00, Prague 2, Czech Republic.

Background: The structural and functional changes of the skeletal muscles in idiopathic inflammatory myopathies (IIM) caused by inflammation and immune changes can be severely disabling. The objective of this study was to assess the effect of a 24-week program combining a supervised training of activities of daily living (ADL), resistance, and stability with home exercise for improving muscle function, compared to a daily home-based exercise representing the regular outpatient care.

Methods: Fifty-seven patients with IIM were consecutively and non-selectively enrolled in an intervention (IG, n = 30) or control (CG, n = 27) group. Read More

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Evaluation of characteristics and microbial community of anaerobic granular sludge under microplastics and aromatic carboxylic acids exposure.

Sci Total Environ 2021 Jun 8;792:148361. Epub 2021 Jun 8.

Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection, Guangxi Normal University, Ministry of Education, 15 Yucai Road, Guilin 541004, PR China.

The influences of polyether sulfone (PES) microplastics and different structures aromatic carboxylic acids such as benzoic acid (BA), phthalic acid (PA), hemimellitic acid (HA), and 1-naphthoic acid (1-NA) on the performances and characteristics of anaerobic granular sludge as well as the microbial community were investigated. The chemical oxygen demand (COD) removal efficiency was the highest in the experimental group with 40 mg/L BA, reaching 90.1%. Read More

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Dimensions of holistic thinking: Implications for nonsocial information processing across cultures.

J Exp Psychol Gen 2021 Jun 21. Epub 2021 Jun 21.

Department of Marketing.

Representatives of Asian and Western countries often differ in terms of both their social orientation (e.g., collectivism vs. Read More

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Molecular Dynamics Simulation of Ion Adsorption and Ligand Exchange on an Orthoclase Surface.

ACS Omega 2021 Jun 4;6(23):14952-14962. Epub 2021 Jun 4.

School of Chemical and Environmental Engineering, China University of Mining and Technology (Beijing), Beijing 100083, China.

Orthoclase (K-feldspar) is one of the natural inorganic materials, which shows remarkable potential toward removing heavy metal ions from aqueous solutions. Understanding the interactions of the orthoclase and metal ions is important in the treatment of saline wastewater. In this paper, molecular dynamics simulations were used to prove the adsorption of different ions onto orthoclase. Read More

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Effects of Instead of Antibiotics on Growth Performance, Intestinal Health, and Intestinal Microbiota of Broilers.

Front Vet Sci 2021 4;8:679368. Epub 2021 Jun 4.

Key Laboratory of Animal Molecular Nutrition of Education of Ministry, National Engineering Laboratory of Biological Feed Safety and Pollution Prevention and Control, Key Laboratory of Animal Feed and Nutrition of Zhejiang Province, Institute of Animal Nutrition and Feed Sciences, College of Animal Sciences, Zhejiang University, Hangzhou, China.

The aim of this study was to evaluate the dietary effects of SC06 (SC06) instead of antibiotics on the growth performance, intestinal health, and intestinal microbiota of broilers. A total of 360 30-day-old Lingnan yellow broilers were randomly allocated into two groups with six replicates per group (30 birds per replicate). The broilers were fed either a non-supplemented diet or a diet supplemented with 10 colony-forming units lyophilized SC06 per kilogram feed for 30 days. Read More

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Water quality evaluation and non-cariogenic risk assessment of exposure to nitrate in groundwater resources of Kamyaran, Iran: spatial distribution, Monte-Carlo simulation, and sensitivity analysis.

J Environ Health Sci Eng 2021 Jun 26;19(1):1117-1131. Epub 2021 May 26.

Department of Environmental Health, Food Safety Division, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

Water is exceptionally vital for all living beings and socio-economic development. This study aimed to investigate the groundwater suitability for drinking in rural areas of Kamyaran city, Kurdistan province, Iran, by using the water quality index (WQI) and evaluating the non-carcinogenic health risk caused by nitrate from the drinking route. Forty-five groundwater samples were collected (2019) from operated dug-wells, and twelve parameters (TDS, pH, TH, EC, HCO, K, Na, Mg, Ca, Cl, SO, and NO) were measured to the calculation of WQI. Read More

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Engineering Leaf-Like UiO-66-SOH Membranes for Selective Transport of Cations.

Nanomicro Lett 2020 Feb 17;12(1):51. Epub 2020 Feb 17.

CAS Key Laboratory of Soft Matter Chemistry, iCHEM (Collaborative Innovation Center of Chemistry for Energy Materials), Department of Applied Chemistry, School of Chemistry and Materials Science, University of Science and Technology of China, Hefei, 230026, People's Republic of China.

Metal-organic frameworks (MOFs) with angstrom-sized pores are promising functional nanomaterials for the fabrication of cation permselective membranes (MOF-CPMs). However, only a few research reports show successful preparation of the MOF-CPMs with good cation separation performance due to several inherent problems in MOFs, such as arduous self-assembly, poor water resistance, and tedious fabrication strategies. Besides, low cation permeation flux due to the absence of the cation permeation assisting functionalities in MOFs is another big issue, which limits their widespread use in membrane technology. Read More

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February 2020

Facility-based and home-based multidomain interventions including cognitive training, exercise, diet, vascular risk management, and motivation for older adults: a randomized controlled feasibility trial.

Aging (Albany NY) 2021 Jun 18;13. Epub 2021 Jun 18.

Department of Neurology, Inha University School of Medicine, Incheon 22332, Republic of Korea.

We aimed to evaluate the feasibility of multidomain intervention (MI) tailored to the Korean context. In an outcome assessor-blinded, randomized controlled trial, participants without dementia and with one or more modifiable dementia risk factors, aged 60-79 years, were randomly assigned to the facility-based MI (FMI; n=51), the home-based MI (HMI; n=51), or the control group receiving general health advice (n=50). The 24-week intervention comprised vascular risk management, cognitive training, social activity, physical exercise, nutrition guidance, and motivational enhancement. Read More

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Recovery of polymeric substances from excess sludge: Surfactant-enhanced ultrasonic extraction and properties analysis.

Chemosphere 2021 Jun 14;283:131181. Epub 2021 Jun 14.

Beijing Key Laboratory of Resource-oriented Treatment of Industrial Pollutants, University of Science and Technology Beijing, 30 Xueyuan Road, Haidian District, Beijing, 100083, China.

The recovery of polymeric substances from excess sludge is gaining significant research interest in future wastewater treatment technologies. We present a surfactant-enhanced ultrasonic method to extract mixed polymeric substances with typical functional groups from excess sludge. Four potential reasons were revealed for the higher efficiency upon ultrasonication with surfactant: low surface tension, damage of non-covalent bonds between extracellular polymeric substances and cells, enhanced dissolution of polymeric substances, and release of intracellular polymeric substances caused by cell lysis. Read More

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Physico-chemical characterization of bilirubin-10-sulfonate and comparison of its acid-base behavior with unconjugated bilirubin.

Sci Rep 2021 Jun 18;11(1):12896. Epub 2021 Jun 18.

Institute of Medical Biochemistry and Laboratory Diagnostics, 1st Faculty of Medicine, Charles University, Na Bojišti 3, Praha 2, 12000, Czech Republic.

Unconjugated bilirubin (UCB) is the end-product of heme catabolism in the intravascular compartment. Although beneficial for human health when mildly elevated in the body, when present at greater than a critical threshold concentration, UCB exerts toxic effects that are related to its physico-chemical properties, particularly affecting the central nervous system. The aim of the present study was to characterize bilirubin-10-sulfonate (ranarubin), a naturally occurring bile pigment, including determination of its mixed acidity constants (pK). Read More

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Puerarin-Na Chelate Hydrate Simultaneously Improves Dissolution and Mechanical Behavior.

Mol Pharm 2021 Jun 18. Epub 2021 Jun 18.

School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 211198, PR China.

Puerarin monohydrate (PUEM), as the commercial solid form of the natural anti-hypertension drug puerarin (PUE), has low solubility, poor flowability, and mechanical properties. In this study, a novel solid form as PUE-Na chelate hydrate was prepared by a reactive crystallization method. Crystal structure analysis demonstrated that PUE-Na contains PUE, Na, and water in a molar ratio of 1:1:7. Read More

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Pancake-Like MOF Solid-State Electrolytes with Fast Ion Migration for High-Performance Sodium Battery.

Nanomicro Lett 2021 Apr 5;13(1):105. Epub 2021 Apr 5.

State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, School of Materials Science and Engineering, Wuhan University of Technology, Wuhan, 430070, People's Republic of China.

Solid-state electrolyte (SSE) of the sodium-ion battery have attracted tremendous attention in the next generation energy storage materials on account of their wide electrochemical window and thermal stability. However, the high interfacial impedance, low ion transference number and complex preparation process restrict the application of SSE. Herein, inspired by the excellent sieving function and high specific surface area of red blood cells, we obtained a solid-like electrolyte (SLE) based on the combination of the pancake-like metal-organic framework (MOF) with liquid electrolyte, possessing a high ionic conductivity of 6. Read More

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A Novel Strategy of In Situ Trimerization of Cyano Groups Between the TiCT (MXene) Interlayers for High-Energy and High-Power Sodium-Ion Capacitors.

Nanomicro Lett 2020 Jun 25;12(1):135. Epub 2020 Jun 25.

School of Materials Science and Engineering, State Key Laboratory of Fine Chemicals, Key Laboratory of Energy Materials and Devices (Liaoning Province), Dalian University of Technology, Dalian, 116024, People's Republic of China.

2D MXenes are attractive for energy storage applications because of their high electronic conductivity. However, it is still highly challenging for improving the sluggish sodium (Na)-ion transport kinetics within the MXenes interlayers. Herein, a novel nitrogen-doped TiCT MXene was synthesized by introducing the in situ polymeric sodium dicyanamide (Na-dca) to tune the complex terminations and then utilized as intercalation-type pseudocapacitive anode of Na-ion capacitors (NICs). Read More

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Protective Effect of Joa-Gui Em through the Improvement of the NLRP3 and TLR4/NF-b Signaling by Ischemia/Reperfusion-Induced Acute Renal Failure Rats.

Evid Based Complement Alternat Med 2021 28;2021:7178868. Epub 2021 May 28.

College of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, Iksan 54538, Republic of Korea.

Joa-gui em (, JGE) is known to be effective for treating kidney-yin deficient syndrome. However, there is a lack of objective pharmacological research on improving kidney function. This study was designed to evaluate whether JGE improves renal function and related mechanisms in rats with acute renal injury induced by ischemia/reperfusion (I/R). Read More

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2020 KSC/KATRD guideline for the diagnosis and treatment of pulmonary hypertension: Executive summary.

Tuberc Respir Dis (Seoul) 2021 Jun 4. Epub 2021 Jun 4.

Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Yonsei University Health System, Seoul, South Korea.

Pulmonary hypertension (PH) is a condition of increased blood pressure in the pulmonary arteries and is diagnosed with increased a mean pulmonary artery pressure ≥25mmHg. It may involve multiple clinical situations. There are five clinical groups according to similar pathophysiological mechanisms, clinical presentation, hemodynamic profiles, and treatment strategies. Read More

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Assessment of the hydrochemistry, water quality, and human health risk of groundwater in the northwest of Nansi Lake Catchment, north China.

Environ Geochem Health 2021 Jun 15. Epub 2021 Jun 15.

801 Institute of Hydrogeology and Engineering Geology, Shandong Provincial Bureau of Geology & Mineral Resources, Jinan, 250014, China.

In this study, the formation mechanism and water quality of groundwater in the northwest of Nansi Lake Catchment (NNLC) were analyzed through mathematical statistics, hydrochemical analysis and entropy weighted water quality index (EWQI), and the human health risk of nitrate was also evaluated. To this end, 89 wells in the NNLC were sampled, and the groundwater samples were divided into three groups (I, II, and III) according to cluster analysis results and spatial distribution. The main results are as follows: Topographically, Groups I, II, and III correspond to the alluvial plains, apron plain, and low hills and its front margin, respectively. Read More

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Assessing the Benefit-Risk Ratio of Approved Treatments for Bipolar Depression Using Likelihood to be Helped or Harmed (LHH) Analyses.

CNS Spectr 2021 Apr;26(2):146

Sunovion Pharmaceuticals Inc., Fort Lee, NJ and Marlborough, MA, USA.

Background: Four medications are FDA approved for bipolar depression: lurasidone (LUR), cariprazine (CAR), quetiapine IR & XR (QUE), and olanzapine-fluoxetine combination (OFC). Indirect comparisons for efficacy using Number Needed to Treat (NNT) and for tolerability using Number Needed to Harm (NNH) can be useful clinical benchmarks to aid treatment decisions. Benefit and risk may also be examined using the Likelihood to be Helped or Harmed (LHH). Read More

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Clinical profiles of college student patients in a psychiatric hospital.

J Psychiatr Res 2021 Jun 4;140:289-294. Epub 2021 Jun 4.

College Mental Health Program, McLean Hospital, 115 Mill St, Belmont, MA, USA; Harvard Medical School, 25 Shattuck St, Boston, MA, USA. Electronic address:

College students represent a significant portion of patients in a psychiatric hospital. However, limited previous research has examined the clinical profiles of this unique population, especially across both inpatient and outpatient settings. To better understand college student mental health, the current study explored the potentially heterogeneous groups of students admitted to inpatient or treated in outpatient units in a large psychiatric hospital. Read More

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Effect of Daily Iron Supplementation on Infantile Iron Homeostasis in Preterm Infants.

Front Pediatr 2021 28;9:687119. Epub 2021 May 28.

Department of Pediatric Health Care, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, China.

The aim of this study was to investigate the effects of unified iron supplementation and identify the factors related to the iron homeostasis among preterm infants. A total of 250 preterm infants were divided into neonatal anemic (NA, = 154) and non-neonatal anemic group (NNA, = 96). Iron supplements at a dose of 2 mg/kg per day were given from 40 weeks' gestational age to 6 months. Read More

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Impact of Bisoprolol on Ventricular Arrhythmias in Experimental Myocardial Infarction.

Chonnam Med J 2021 May 24;57(2):132-138. Epub 2021 May 24.

Department of Pathology, Busan National University Yangsan Hospital, Yangsan, Korea.

Following acute myocardial infarction (AMI), early use of beta-blockers (BBs) reduced the incidences of ventricular arrhythmia (VA) and death in the pre reperfusion era. However, some studies have reported a worsening of clinical outcomes and therefore, this study used a porcine model of AMI to evaluate the efficacy of bisoprolol on VAs and mortality. Twenty pigs were divided into two groups with one group using oral bisoprolol which was given for 3 hours before the experiment and then maintained for 7 days. Read More

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Effects of visual search task on attentional bias and stress response under pressure.

Yonghui Jin Jun He

Work 2021 Jun 6. Epub 2021 Jun 6.

School of Economics, Liaoning University, Liaoning, Shenyang, China.

Background: it has always been a problem for athletes that their performance is out of order due to pressure in major competitions. The change of attention pattern and the emergence of stress response (SR) caused by negative affect (NA)are the direct reasons for the greater impact on the performance of athletes. It is a hot topic to explore how to improve attention bias (AB) and SR of athletes in stressful situations. Read More

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Demonstration of Advanced Glycation End product (AGE) Expression in Bladder Cancer Tissue in Type 2 Diabetic and Non-diabetic Patients and the Relationship between AGE Accumulation and Endoplasmic Reticulum Stress (ERS) with Bladder Cancer.

Int J Clin Pract 2021 Jun 13:e14526. Epub 2021 Jun 13.

Department of Urology, Faculty of Medicine, University of Çukurova, Adana, Turkey.

Purpose: This study aimed to investigate the relationship between Advanced Glycation End (AGE) product expression and accumulation in transurethral resection (TUR-B) material taken from Type 2 DM and Non-DM bladder cancer patients and Endoplasmic Reticulum stress (ERS) with bladder cancer.

Method: The patients who had TUR-B between May 2016 and September 2018 were included in the study. After the tissue samples had been taken and frozen at -80 °C, they were homogenized to be used in ELISA experiments. Read More

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