64,679 results match your criteria groups maternal


Dystrophin and metalloproteinase 9 in myocardial ischemia: A post-mortem immunohistochemical study.

Leg Med (Tokyo) 2021 Jul 25;53:101948. Epub 2021 Jul 25.

Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, via Consolare Valeria, 1, 98125 Messina, Italy.

The presented study evaluated the expression of dystrophin and MMP-9 in cases of sudden cardiac death (SCD) due to coronary atherosclerotic disease (CAD) in order to analyze the characteristics and the chronology of their expression, providing evidence on the possible role in post-mortem diagnosis of myocardial ischemia. The expression of these proteins was also compared to C5b-9 complex and fibronectin expression to evaluate any differences. Two groups of CAD-related SCD, respectively group 1 with gross and/or histological evidence and group 2 with no specific histological signs of myocardial ischemia, were used. Read More

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History of IUD utilization and the risk of preterm birth: a cohort study.

Arch Gynecol Obstet 2021 Jul 30. Epub 2021 Jul 30.

Dongguan Maternal and Child Health Care Hospital, No.99 Zhenxing Road, Dongcheng District, Dongguan City, 523112, Guangdong Province, China.

Objective: To explore whether a history of IUD use could increase the risk of subsequent preterm birth.

Methods: We performed a cohort study of 24,496 multipara aged 19-48 years in Dongguan City. Each subject was followed up for 1 year, and 12,508 women obtained pregnancy outcomes. Read More

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The food patterns of a multicenter cohort of Brazilian nulliparous pregnant women.

Sci Rep 2021 Jul 30;11(1):15554. Epub 2021 Jul 30.

Department of Obstetrics and Gynaecology, University of Campinas (UNICAMP), School of Medicine, Campinas, SP, Brazil.

Assessment of human nutrition is a complex process, in pregnant women identify dietary patterns through mean nutrient consumption can be an opportunity to better educate women on how to improve their overall health through better eating. This exploratory study aimed to identify a posteriori dietary patterns in a cohort of nulliparous pregnant women. The principal component analysis (PCA) technique was performed, with Varimax orthogonal rotation of data extracted from the 24-h dietary recall, applied at 20 weeks of gestation. Read More

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Social Justice as a Tool to Eliminate Inequities in Kidney Disease.

Authors:
J Kevin Tucker

Semin Nephrol 2021 May;41(3):203-210

Renal Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA. Electronic address:

Kidney disease has disparate effects on racial and ethnic minority groups, who have higher rates of chronic kidney disease and generally poorer outcomes. These disparate rates and outcomes have been attributed to social determinants of health; however, these social determinants of health are related to governmental and societal structural barriers that have created inequities not only in kidney disease, but also in other chronic diseases and in maternal/fetal health outcomes. The societal barriers to health equity include income inequality, inadequate education, environmental injustice, mass incarceration, and the enduring effects of the legacy of slavery. Read More

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Socio-economic inequality in anthropometric failure among children aged under 5 years in India: evidence from the Comprehensive National Nutrition Survey 2016-18.

Int J Equity Health 2021 Jul 30;20(1):176. Epub 2021 Jul 30.

Nutrition Specialist, UNICEF, UNICEF House, 73 Lodi Estate, New Delhi, India.

Background: Conventional indicators used to access the nutritional status of children tend to underestimate the overall undernutrition in the presence of multiple anthropometric failures. Further, factors contributing to the rich-poor gap in the composite index of anthropometric failure (CIAF) have not been explored. This study aims to estimate the prevalence of CIAF and quantify the contribution of factors that explain the rich-poor gap in CIAF. Read More

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Expectant management versus multifetal pregnancy reduction in dichorionic triamniotic (DCTA) triplets: Single centre experience.

Eur J Obstet Gynecol Reprod Biol 2021 Jul 13;264:200-205. Epub 2021 Jul 13.

Queen Charlotte's and Chelsea Hospital, Imperial Healthcare NHS Trust, UK; Institute of Reproductive and Developmental Biology, Imperial College London, UK; Department of Development and Regeneration, KU Leuven, Belgium. Electronic address:

Objectives: In trichorionic triplet pregnancies, multifetal pregnancy reduction (MFPR) reduces the risk of preterm birth, neonatal morbidity and mortality without increasing miscarriage. A similar benefit has been suggested in dichorionic triamniotic (DCTA) pregnancy, but multiple methods are currently used. This study investigates if the method of reduction used in DCTA triplet pregnancy influences the evidence of benefit from MFPR. Read More

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SARS-CoV-2 Antibodies and Associated Factors at Different Hospitalization Time Points in 192 COVID-19 Cases.

J Appl Lab Med 2021 Jul 30. Epub 2021 Jul 30.

Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, China.

Background: We launched a retrospective analysis of SARS-CoV-2 antibodies in 192 patients with COVID-19, aiming to depict the kinetic profile of SARS-CoV-2 antibodies and explore the factors related to SARS-CoV-2 antibody expression.

Methods: Data on 192 confirmed patients with COVID-19 between January and February 2020 was collected from the designated hospital that received patients with COVID-19 in Guangzhou, China. Moreover, a cohort of 130 suspected patients with COVID-19 and 209 healthy people were also enrolled in this study. Read More

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Effects of low and high levels of maternal nutrition consumed for the entirety of gestation on the development of muscle, adipose tissue, bone, and the organs of Wagyu cattle fetuses.

Anim Sci J 2021 Dec;92(1):e13600

Faculty of Agriculture, Kagoshima University, Kagoshima, Japan.

This study aimed to investigate the effects of high and low levels of energy intake during the entire gestation period on the skeletal muscle development, organ development, and adipose tissue accumulation in fetuses of Wagyu (Japanese Black) cows, a breed with highly marbled beef. Cows were allocated to a high-nutrition (n = 6) group (fed 120% of the nutritional requirement) or low-nutrition (n = 6) group (fed 60% of the nutritional requirement). The cows were artificially inseminated with semen from the same sire, and the fetuses were removed by cesarean section at 260 ± 8. Read More

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December 2021

Diabetes during pregnancy and birthweight trends among Aboriginal and non-Aboriginal people in the Northern Territory of Australia over 30 years.

Lancet Reg Health West Pac 2020 Aug 24;1:100005. Epub 2020 Jul 24.

Wellbeing and Chronic Preventable Diseases Division, Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia.

Background: Early-life risk factors, including maternal hyperglycaemia and birthweight, are thought to contribute to the high burden of cardiometabolic disease experienced by Indigenous populations. We examined rates of pre-existing diabetes in pregnancy, gestational diabetes mellitus (GDM) and extremes of birthweight over three decades in the Northern Territory (NT) of Australia.

Methods: We performed a retrospective cohort analysis of the NT Perinatal Data Collection from 1987 to 2016, including all births >20 weeks gestation, stratified by maternal Aboriginal identification. Read More

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Human Newborn Monocytes Demonstrate Distinct BCG-Induced Primary and Trained Innate Cytokine Production and Metabolic Activation .

Front Immunol 2021 13;12:674334. Epub 2021 Jul 13.

Precision Vaccines Program, Division of Infectious Diseases, Boston Children's Hospital, Boston, MA, United States.

Background: Newborns exhibit distinct immune responses and are at high risk of infection. Neonatal immunization with BCG, the live attenuated vaccine against tuberculosis (TB), is associated with broad protection against a range of unrelated pathogens, possibly reflecting vaccine-induced training of innate immune cells ("innate memory"). However, little is known regarding the impact of age on BCG-induced innate responses. Read More

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Folic Acid Supplementation during Pregnancy Modulates Hepatic Methyl Metabolism and Genes Expression Profile of Neonatal Lambs of Different Litter Sizes.

Br J Nutr 2021 Jul 30:1-35. Epub 2021 Jul 30.

State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, P.R China.

Maternal folic acid (FA) plays an important role in the fetus development, but it is unknown the response of hepatic metabolism in the offspring from different litter sizes to maternal FA supplementation. In the present study, this was done by feeding the ewes with 0, 16 and 32 mg/(kg·DM) FA supplemented diet during pregnancy and analyzing the hepatic one-carbon metabolism-related indices and gene expression in the neonatal lambs of different litter sizes (twins, TW; triplets, TR). Regardless of litter sizes, the concentrations of folate, methionine, S-Adenosylmethionine and DNA methyltransferase increased significantly, but homocysteine and S- adenosylhomocysteine decreased in the liver of newborn lambs from ewes whose diet was supplemented with FA. Read More

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Relationship between maternal vitamin D status in the first trimester of pregnancy and maternal and neonatal outcomes: a retrospective single center study.

BMC Pediatr 2021 Jul 29;21(1):330. Epub 2021 Jul 29.

International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, 910# Hengshan Road, Shanghai, 20030, China.

Background: This study aimed to investigate the relationship between maternal serum vitamin D status in the first trimester of pregnancy and maternal as well as neonatal outcomes, considered the prevalence of vitamin D deficiency (serum 25(OH)D < 50 nmol/L) around the world, especially in the pregnant women.

Methods: From January 2015 to December 2016, in this cross-sectional retrospective study, we enrolled women receiving regular prenatal examinations and giving birth in the International Peace Maternity and Child Health Hospital. Cases confirmed as multiple pregnancy, incomplete medical records, and vitamin D level recorded after 13 weeks of gestation were excluded. Read More

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Progress Toward Hepatitis B Control - World Health Organization European Region, 2016-2019.

MMWR Morb Mortal Wkly Rep 2021 Jul 30;70(30):1029-1035. Epub 2021 Jul 30.

In 2019, an estimated 14 million persons in the World Health Organization (WHO) European Region* (EUR) were chronically infected with hepatitis B virus (HBV), and approximately 43,000 of these persons died from complications of chronic HBV infection (1). In 2016, the WHO Regional Office for Europe set hepatitis B control program targets for 2020, including 1) ≥90% coverage with 3 doses of hepatitis B vaccine (HepB3), 2) ≥90% coverage with interventions to prevent mother-to-child transmission (MTCT) of HBV, and 3) ≤0.5% prevalence of HBV surface antigen (HBsAg) in age groups eligible for vaccination with hepatitis B vaccine (HepB) (2-4). Read More

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Increased infectious-cause hospitalization among infants who are HIV-exposed uninfected compared to HIV-unexposed.

AIDS 2021 Jul 28. Epub 2021 Jul 28.

Center for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, South Africa Division of Epidemiology and Biostatistics, School of Public Health and Family Medicine, University of Cape Town, South Africa Division of Public Health Medicine, School of Public Health and Family Medicine, University of Cape Town, South Africa Department of Paediatrics and Child Health, Stellenbosch University, South Africa Directorate of Health Impact Assessment, Western Cape Provincial Department of Health, South Africa Paediatric Infectious Diseases Unit, Department of Paediatrics and Child Health, University of Cape Town, South Africa Paediatric Infectious Diseases Unit, Department of Paediatrics and Child Health, Stellenbosch University, South Africa Department of Paediatrics and Child Health, University of Cape Town, South Africa Department of Paediatrics, Mitchells Plain Hospital, South Africa Division of Neonatal Medicine, Department of Pediatrics and Child Health, University of Cape Town, South Africa.

Objectives: Increased risk of morbidity and hospitalization has been observed in children who are HIV-exposed uninfected (HEU) compared to HIV-unexposed uninfected (HUU). Studies in the era of universal maternal antiretroviral treatment (ART) are limited.

Design: Prospective cohort. Read More

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Assessing the added value of GBS maternal immunisation in preventing maternal infection and foetal harm: population surveillance study.

BJOG 2021 Jul 29. Epub 2021 Jul 29.

Healthcare-Associated Infection & Antimicrobial Resistance Division, National Infection Service, Public Health England, London, UK.

Objective: To assess the incidence of maternal group B streptococcal (GBS) infection in England DESIGN: Population surveillance augmented through data linkage.

Setting: England POPULATION: All pregnant women accessing the National Health Service (NHS) in England METHODS: Invasive GBS (iGBS) infections during pregnancy or within six weeks of childbirth were identified by linking Public Health England (PHE) national microbiology surveillance data for 2014 to NHS hospital admission records. Capsular serotypes of GBS were determined by reference laboratory typing of clinical isolates from women aged 15-44y. Read More

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Dual task gait deteriorates gait performance in cervical dystonia patients: a pilot study.

J Neural Transm (Vienna) 2021 Jul 29. Epub 2021 Jul 29.

Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, Italy.

Day-to-day walking-related activities frequently involve the simultaneous performance of two or more tasks (i.e., dual task). Read More

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Preimplantation genetic testing is not a preferred recommendation for patients with X chromosome abnormalities.

Hum Reprod 2021 Jul 27. Epub 2021 Jul 27.

Center for Reproductive Medicine, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.

Study Question: Should women with X chromosome abnormalities (XCAs) be recommended to have embryos selected by both morphological and cytogenetic assessment through preimplantation genetic testing (PGT) rather than morphological assessment only in conventional IVF/ICSI treatment?

Summary Answer: PGT is not a preferred recommendation for women with XCAs in the absence of other PGT indications.

What Is Known Already: XCAs are the most frequent sort of chromosomal aberrations in infertile women. Patients with a complete or partial absence of one X chromosome, diagnosed as Turner Syndrome (TS), demonstrate low spontaneous pregnancy rates (5-7%) and high miscarriage rates (22. Read More

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Cardiac remodeling in fetuses conceived by ARTs: fresh versus frozen embryo transfer.

Hum Reprod 2021 Jul 27. Epub 2021 Jul 27.

BCNatal | Fetal Medicine Research Center (Hospital Clínic and Hospital Sant Joan de Déu), Universitat de Barcelona, Barcelona, Spain.

Study Question: Do fetuses from frozen embryo transfer (FET) present signs of cardiac remodeling and suboptimal function similar to those observed in fetuses from fresh embryo transfer (ET)?

Summary Answer: Fetuses from both fresh ET and FET present signs of fetal cardiac remodeling and suboptimal function, with more pronounced changes after fresh ET as compared to FET.

What Is Known Already: Our group and others have previously demonstrated that fetuses and children conceived by ARTs present cardiac remodeling and suboptimal function. These fetuses show dilated atria, more globular and thicker ventricles, reduced longitudinal motion, and impaired relaxation. Read More

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Saliva nitrite is higher in male children with autism spectrum disorder and positively correlated with serum nitrate.

Redox Rep 2021 Dec;26(1):124-133

International Joint Research Center for General Health, Precision Medicine & Nutrition, Hubei University of Technology, Wuhan, People's Republic of China.

Objectives: Nitric oxide (NO) plays a vital role in neurological development. As an easily accessible and non-invasive fluid, saliva hasn't been evaluated for nitrite among children with autism spectrum disorder (ASD). This study aims to quantify saliva nitrite and explore its relation with serum NO. Read More

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December 2021

Peripartum cardiomyopathy: from genetics to management.

Eur Heart J 2021 Jul 28. Epub 2021 Jul 28.

Department of Cardiology and Angiology, Hannover Medical School, Hannover, Germany.

Peripartum cardiomyopathy (PPCM) is a disease that occurs globally in all ethnic groups and should be suspected in any peripartum women presenting with symptoms and signs of heart failure, towards the end of pregnancy or in the months following delivery, with confirmed left ventricular dysfunction. After good history taking, all women should be thoroughly assessed, and alternative causes should be excluded. Urgent cardiac investigations with electrocardiogram and natriuretic peptide measurement (if available) should be performed. Read More

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The influence of mindfulness-based stress reduction (MBSR) on stress, anxiety and depression due to unwanted pregnancy: a randomized clinical trial.

J Prev Med Hyg 2021 Mar 29;62(1):E82-E88. Epub 2021 Apr 29.

Assistant professor of psychiatry, fellowship of psychosomatic Medicine, MD, Neuroscience Research Center, Institute of Neuropharmacology, Department of Psychiatry, School of medicine, Kerman University of Medical Sciences, Kerman, Iran.

Background: Individuals with unwanted pregnancies often experience high levels of anxiety, stress and depression that associated with maternal-neonatal outcomes. Mindfulness training is a safe and acceptable strategy to support mental health before parturition.

Purpose: The main objective of present study was to evaluate the influence of eight-week application of mindfulness-based stress reduction on stress, anxiety and depression caused by unplanned pregnancy. Read More

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Mint Oil, ɤ-Tocopherol, and Whole Yeast Cell in Sow Diets Enhance Offspring Performance in the Postweaning Period.

Front Vet Sci 2021 12;8:658956. Epub 2021 Jul 12.

Department of Animal Science, South Dakota State University, Brookings, SD, United States.

Times of high metabolic activity in gestation and lactation, as well as periods of stress at weaning, can lead to greater incidences of oxidative stress in the dam and offspring during the suckling and postweaning period. Oxidative stress is an imbalance between prooxidant molecules and the antioxidant defense system that can negatively impact growth and/or reproductive performance. The objective of this research was to evaluate the effectiveness of whole yeast cell, peppermint oil, and ɤ-tocopherol in gestation and lactation on maternal oxidative status and offspring growth from birth to market. Read More

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Increased sugar-sweetened beverage use tendency in pregnancy positively associates with peripartum Edinburgh postpartum depression scores.

Sci Rep 2021 Jul 28;11(1):15324. Epub 2021 Jul 28.

Department of Obstetrics and Gynecology, Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.

The association among sugar sweetened beverages (SSB) consumption, addiction and depression in adults, children and adolescents is widely reported. Dieting patterns during pregnancy is complicated by maternal fetal concerns. Specifically, restrained use of SSB might be potentially a source of perinatal distress. Read More

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Endocrine disrupting chemical-associated hair product use during pregnancy and gestational age at delivery: a pilot study.

Environ Health 2021 Jul 28;20(1):86. Epub 2021 Jul 28.

Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.

Background: Prenatal endocrine disrupting chemical (EDC) exposure has been associated with increased risk of preterm birth. Non-Hispanic Black women have higher incidence of preterm birth compared to other racial/ethnic groups and may be disproportionately exposed to EDCs through EDC-containing hair products. However, research on the use of EDC-associated hair products during pregnancy and risk of preterm birth is lacking. Read More

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Factors influencing childhood immunisation uptake in Africa: a systematic review.

BMC Public Health 2021 Jul 28;21(1):1475. Epub 2021 Jul 28.

Department of Community Health, Faculty of Medicine and Health Sciences, University Putra Malaysia, Serdang, Malaysia.

Background: Vaccine preventable diseases are still the most common cause of childhood mortality, with an estimated 3 million deaths every year, mainly in Africa and Asia. An estimate of 29% deaths among children aged 1-59 months were due to vaccine preventable diseases. Despite the benefits of childhood immunisation, routine vaccination coverage for all recommended Expanded Programme on Immunization vaccines has remained poor in some African countries, such as Nigeria (31%), Ethiopia (43%), Uganda (55%) and Ghana (57%). Read More

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Transparent reporting of recruitment and informed consent approaches in clinical trials recruiting children with minor parents in sub-Saharan Africa: a secondary analysis based on a systematic review.

BMC Public Health 2021 Jul 28;21(1):1473. Epub 2021 Jul 28.

Swiss Tropical and Public Health Institute, Basel, Switzerland.

Background: Standardised checklists of items to be addressed in clinical study protocols and publications are promoting transparency in research. However, particular specifications for exceptional cases, such as children with minor parents are missing. This study aimed to examine the level of transparency regarding recruitment and informed consent approaches in publications of clinical trials recruiting children with minor parents in sub-Saharan Africa. Read More

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Effects of delayed cord clamping on neonatal hyperbilirubinemia in pre-gestational diabetes at term.

J Matern Fetal Neonatal Med 2021 Jul 29:1-9. Epub 2021 Jul 29.

Obstetrics, Gynecology and Women's Health Institute, Cleveland Clinic, Cleveland, OH, USA.

Objective: To evaluate the effects of delayed cord clamping on neonatal hyperbilirubinemia in infants born to patients diagnosed with pre-gestational diabetes (type I or type II).

Methods: In January 2016, our institution implemented an organization-wide thirty-second delayed cord clamping protocol. This retrospective cross-sectional study represents infants of mothers diagnosed with pre-gestational diabetes who delivered before and after protocol implementation. Read More

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Revisiting an RCT study of a parent education program for Latinx parents in the United States: Are treatment effects maintained over time?

Autism 2021 Jul 28:13623613211033108. Epub 2021 Jul 28.

Arizona State University, USA.

Lay Abstract: We conducted a follow-up investigation of a two-site randomized controlled trial in the United States. We examined whether the treatment effects in a culturally tailored parent education program for Latinx families of children with autism spectrum disorder were maintained over time. Using linear mixed models, we compared differences in parent and child outcomes across three timepoints: baseline, 4 months after baseline (Time 2), and 8 months after baseline (T3). Read More

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Predictive Role of First-trimester ELABELA Levels for Late-onset Preeclampsia.

J Coll Physicians Surg Pak 2021 Aug;31(8):916-920

Department of Obstetrics and Gynecology, Zeynep Kamil Women and Children Disease Training and Research Hospital, Istanbul, Turkey.

Objective: To determine the predictive role of first trimester maternal serum ELABELA (ELA) levels in late-onset preeclampsia (PE).

Study Design: Comparative descriptive study.

Place And Duration Of Study: Department of Obstetrics and Gynecology, Bursa Yüksek İhtisas Training and Research Hospital, Bursa, Turkey between January and September 2019. Read More

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Association between maternal hypertensive disorders, fetal growth and childhood learning outcomes.

Pregnancy Hypertens 2021 Jul 21;25:249-254. Epub 2021 Jul 21.

Women & Infants Hospital of Rhode Island, Alpert Medical School at Brown University, Providence, RI, United States; Hassenfeld Child Health Innovation Institute, Brown University, Providence, RI, United States.

Objective: Both small for gestational age (SGA) birthweight and pregnancies complicated by maternal hypertension (HTN) are independently associated with poorer childhood learning outcomes, however the relative contribution of each remains unknown.

Study Design: A retrospective cohort was created in which 2014-2017 third grade Rhode Island Department of Education data were linked to Rhode Island Department of Health birth certificate data. The study population was composed of non-anomalous, singleton births between 22- and 42-weeks' gestation. Read More

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