76 results match your criteria group self-produced

Intact Correction for Self-Produced Vowel Formant Variability in Individuals With Cerebellar Ataxia Regardless of Auditory Feedback Availability.

J Speech Lang Hear Res 2021 Jun 26;64(6S):2234-2247. Epub 2021 Apr 26.

Department of Otolaryngology, University of California, San Francisco.

Purpose Individuals with cerebellar ataxia (CA) caused by cerebellar degeneration exhibit larger reactive compensatory responses to unexpected auditory feedback perturbations than neurobiologically typical speakers, suggesting they may rely more on feedback control during speech. We test this hypothesis by examining variability in unaltered speech. Previous studies of typical speakers have demonstrated a reduction in formant variability (centering) observed during the initial phase of vowel production from vowel onset to vowel midpoint. Read More

View Article and Full-Text PDF

Self-produced audio-visual animation introduction alleviates preoperative anxiety in pediatric strabismus surgery: a randomized controlled study.

BMC Ophthalmol 2021 Apr 7;21(1):163. Epub 2021 Apr 7.

Department of Anesthesiology, The First Affiliated Hospital of Wenzhou Medical University, South Baixiang Town, Wenzhou, Zhejiang, China.

Background: Hospital anxiety caused by strabismus surgery has an unpleasant and disturbing feeling for both children and their parents. This study aimed to determine the effect of viewing a self-produced audio-visual animation introduction on preoperative anxiety and emergence agitation of pediatric patients undergoing strabismus surgery.

Methods: In this prospective randomized study, 1 hundred children scheduled for strabismus surgery with aged 3 ~ 6 years. Read More

View Article and Full-Text PDF

Bacillus subtilis biofilm formation and social interactions.

Nat Rev Microbiol 2021 Apr 6. Epub 2021 Apr 6.

Bacterial Interactions and Evolution Group, DTU Bioengineering, Technical University of Denmark, Kongens Lyngby, Denmark.

Biofilm formation is a process in which microbial cells aggregate to form collectives that are embedded in a self-produced extracellular matrix. Bacillus subtilis is a Gram-positive bacterium that is used to dissect the mechanisms controlling matrix production and the subsequent transition from a motile planktonic cell state to a sessile biofilm state. The collective nature of life in a biofilm allows emergent properties to manifest, and B. Read More

View Article and Full-Text PDF

Bacterial biofilm-derived antigens: a new strategy for vaccine development against infectious diseases.

Expert Rev Vaccines 2021 Mar 8:1-15. Epub 2021 Mar 8.

Immunology & Vaccinology Group. Centro de Investigaciones Biológicas del Noroeste, SC. Instituto Politécnico Nacional 195, Playa Palo de Santa Rita Sur, La Paz, BCS, México.

Introduction: Microorganisms can develop into a social organization known as biofilms and these communities can be found in virtually all types of environment on earth. In biofilms, cells grow as multicellular communities held together by a self-produced extracellular matrix. Living within a biofilm allows for the emergence of specific properties for these cells that their planktonic counterparts do not have. Read More

View Article and Full-Text PDF

I'm a believer: Illusory self-generated touch elicits sensory attenuation and somatosensory evoked potentials similar to the real self-touch.

Neuroimage 2021 04 9;229:117727. Epub 2021 Jan 9.

SAMBA (SpAtial, Motor and Bodily Awareness) Research Group, Department of Psychology, University of Turin, 10123 Turin, Italy; NIT (Neuroscience Institute of Turin), 10123 Turin, Italy. Electronic address:

Sensory attenuation (i.e., the phenomenon whereby self-produced sensations are perceived as less intense compared to externally occurring ones) is among the neurocognitive processes that help distinguishing ourselves from others. Read More

View Article and Full-Text PDF

Singularities of Pyogenic Streptococcal Biofilms - From Formation to Health Implication.

Front Microbiol 2020 23;11:584947. Epub 2020 Dec 23.

UCIBIO, Departamento Ciências da Vida, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Campus de Caparica, Caparica, Portugal.

Biofilms are generally defined as communities of cells involved in a self-produced extracellular matrix adhered to a surface. In biofilms, the bacteria are less sensitive to host defense mechanisms and antimicrobial agents, due to multiple strategies, that involve modulation of gene expression, controlled metabolic rate, intercellular communication, composition, and 3D architecture of the extracellular matrix. These factors play a key role in streptococci pathogenesis, contributing to therapy failure and promoting persistent infections. Read More

View Article and Full-Text PDF
December 2020

A causal role for the right angular gyrus in self-location mediated perspective taking.

Sci Rep 2020 11 5;10(1):19229. Epub 2020 Nov 5.

Consciousness, Cognition, and Computation Group (CO3), Centre for Research in Cognition and Neurosciences (CRCN), ULB Neuroscience Institute (UNI), Université Libre de Bruxelles (ULB), Avenue F.D. Roosevelt 50, CP191, 1050, Brussels, Belgium.

Recent theories suggest that self-consciousness, in its most elementary form, is functionally disconnected from the phenomenal body. Patients with psychosis frequently misattribute their thoughts and actions to external sources; and in certain out-of-body experiences, lucid states, and dreams body-ownership is absent but self-identification is preserved. To explain these unusual experiences, we hypothesized that self-identification depends on inferring self-location at the right angular gyrus (i. Read More

View Article and Full-Text PDF
November 2020

Privatization of Biofilm Matrix in Structurally Heterogeneous Biofilms.

mSystems 2020 Aug 4;5(4). Epub 2020 Aug 4.

Bacterial Interactions and Evolution Group, Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark

The self-produced biofilm provides beneficial protection for the enclosed cells, but the costly production of matrix components makes producer cells susceptible to cheating by nonproducing individuals. Despite detrimental effects of nonproducers, biofilms can be heterogeneous, with isogenic nonproducers being a natural consequence of phenotypic differentiation processes. For instance, in biofilm cells differ in production of the two major matrix components, the amyloid fiber protein TasA and exopolysaccharides (EPS), demonstrating different expression levels of corresponding matrix genes. Read More

View Article and Full-Text PDF

Acid soluble extracellular matrix confers structural stability to marine Bacillus haynesii pellicle biofilms.

Colloids Surf B Biointerfaces 2020 Oct 2;194:111160. Epub 2020 Jun 2.

Homi Bhabha National Institute, Anushakti Nagar, Mumbai, 400094, India; Bioscience Group, Bhabha Atomic Research Centre, Trombay, Mumbai, 400085, India.

In natural and engineered settings, bacteria predominantly thrive in biofilms, which are complex microbial communities embedded in a self-produced extracellular polymeric substances (EPSs) matrix. Pellicles are complex macroscopic biofilms floating at air-water interface. Though pellicle formation has been studied in detail in Bacillus subtilis, a soil bacterium, it is not reported in aquatic bacteria, which may use pellicle-growth as survival-strategy. Read More

View Article and Full-Text PDF
October 2020

Neocortical activity tracks the hierarchical linguistic structures of self-produced speech during reading aloud.

Neuroimage 2020 08 26;216:116788. Epub 2020 Apr 26.

Laboratoire de Cartographie Fonctionnelle du Cerveau, UNI - ULB Neuroscience Institute, Université Libre de Bruxelles (ULB), Brussels, Belgium; Magnetoencephalography Unit, Department of Functional Neuroimaging, Service of Nuclear Medicine, CUB - Hôpital Erasme, Brussels, Belgium.

How the human brain uses self-generated auditory information during speech production is rather unsettled. Current theories of language production consider a feedback monitoring system that monitors the auditory consequences of speech output and an internal monitoring system, which makes predictions about the auditory consequences of speech before its production. To gain novel insights into underlying neural processes, we investigated the coupling between neuromagnetic activity and the temporal envelope of the heard speech sounds (i. Read More

View Article and Full-Text PDF

BIPEP: Sequence-based Prediction of Biofilm Inhibitory Peptides Using a Combination of NMR and Physicochemical Descriptors.

ACS Omega 2020 Apr 26;5(13):7290-7297. Epub 2020 Mar 26.

Laboratory of Complex Biological Systems and Bioinformatics (CBB), Department of Bioinformatics, Institute of Biochemistry and Biophysics (IBB), University of Tehran, Tehran 1417466191, Iran.

Biofilms are biological systems that are formed by a community of microorganisms in which microbial cells are connected on a surface within a self-produced matrix of an extracellular polymeric substance. On some occasions, microorganisms use biofilms to protect themselves against the harmful effects of the host body immune system and the surrounding environment, hence increasing their chances of survival against the various anti-microbial agents. Biofilms play a crucial role in medicine and industry because of the problems they cause. Read More

View Article and Full-Text PDF

Impact of genetic mutations and nutritional status on the survival of patients with colorectal cancer.

BMC Cancer 2019 Jun 29;19(1):644. Epub 2019 Jun 29.

Department of Medicine. Gastroenterology Division. Oncology Group, Universidade Federal de São Paulo - SP. Brazil, R Botucatu 740, 2° andar CEP 04023900, Vila Clementino, São Paulo, Brazil.

Background: The prognosis of colorectal cancer (CRC) patients can be influenced by genetic mutations and nutritional status. The relationship between these variables is unclear. The objective of the study was to verify the variables involved in the nutritional status and genetic mutations, which correlate with survival of CRC patients. Read More

View Article and Full-Text PDF

Fluidic resistance control enables high-throughput establishment of mixed-species biofilms.

Biotechniques 2019 05;66(5):235-239

Section of Microbiology, Universitetsparken 15, Department of Biology, Faculty of Science, University of Copenhagen, 2100 Copenhagen, Denmark.

Bacteria often live in communities of mixed species embedded in a self-produced extracellular matrix of polysaccharides, proteins and DNA, termed biofilms. The BioFlux microfluidic flow system is useful for studying biofilm formation in different media under flow. However, analyzing the architecture and maturation of biofilms under flow requires a proper seeding, which can prove difficult when working with bacteria of different sizes, motile bacteria or aiming for a high number of replicates. Read More

View Article and Full-Text PDF

Current Understanding of Group A Streptococcal Biofilms.

Curr Drug Targets 2019 ;20(9):982-993

School of Chemistry and Molecular Bioscience, and Illawarra Health and Medical Research Institute, University of Wollongong, Wollongong, Australia.

Background: It has been proposed that GAS may form biofilms. Biofilms are microbial communities that aggregate on a surface, and exist within a self-produced matrix of extracellular polymeric substances. Biofilms offer bacteria an increased survival advantage, in which bacteria persist, and resist host immunity and antimicrobial treatment. Read More

View Article and Full-Text PDF

Visualization of Intensity Levels to Reduce the Gap Between Self-Reported and Directly Measured Physical Activity.

J Vis Exp 2019 03 7(145). Epub 2019 Mar 7.

Institute of Social Medicine and Prevention, University Medicine Greifswald; partner site Greifswald, DZHK (German Centre for Cardiovascular Research).

Physical activity (PA) assessment needs tools that are inexpensive and easy to administer. Common questionnaires inquire time spent in light, moderate, and vigorous PA. However, inaccuracies may occur due to individually different understanding of PA intensity levels. Read More

View Article and Full-Text PDF

Observation of an expert model induces a skilled movement coordination pattern in a single session of intermittent practice.

Sci Rep 2019 03 14;9(1):4609. Epub 2019 Mar 14.

Edmond J. Safra Brain Research Center for the Study of Learning Disabilities, University of Haifa, Haifa, Israel.

We tested how observation of a skilled pattern of planar movements can assist in the learning of a new motor skill, which otherwise requires rigorous long-term practice to achieve fast and smooth performance. Sixty participants performed a sequence of planar hand movements on pre-test, acquisition, post-test and 24 h post-training blocks, under 1 of 4 conditions: an observation group (OG), a slowed observation group (SOG), a random motion control group (RMCG) and a double physical training control group (DPTCG). The OG and SOG observed an expert model's right hand performing the study task intermittently throughout acquisition, RMCG observed random dots movement instead of a model. Read More

View Article and Full-Text PDF

Bacterial biofilm in adenoids of children with chronic otitis media. Part I: a case control study of prevalence of biofilms in adenoids, risk factors and middle ear biofilms.

Acta Otolaryngol 2019 Apr 26;139(4):345-350. Epub 2019 Feb 26.

e Department of Pediatric Otorhinolaryngology , Head & Neck Surgery, Robert Debré University Hospital APHP, Paris 7 University, Sorbonne Cité , Paris , France.

Background: Biofilms are communities of bacteria embedded in a self-produced glycocalyx matrix. Adenoids have been shown to harbor bacterial biofilms. Aim/objectives: To compare the prevalence of biofilms in adenoid of children with chronic otitis media (COM) (group1) versus a control group without any COM (group 2) having adenoids removed because of hypertrophy. Read More

View Article and Full-Text PDF

Sizable Scaffold-Free Tissue-Engineered Articular Cartilage Construct for Cartilage Defect Repair.

Artif Organs 2019 Mar 29;43(3):278-287. Epub 2018 Oct 29.

Cell Therapy Center, Ajou University Medical center, Suwon, Korea.

This study introduces an implantable scaffold-free cartilage tissue construct (SF) that is composed of chondrocytes and their self-produced extracellular matrix (ECM). Chondrocytes were grown in vitro for up to 5 weeks and subjected to various assays at different time points (1, 7, 21, and 35 days). For in vivo implantation, full-thickness defects (n = 5) were manually created on the trochlear groove of the both knees of rabbits (16-week old) and 3 week-cultured SF construct was implanted as an allograft for a month. Read More

View Article and Full-Text PDF

Listening to yourself is special: Evidence from global speech rate tracking.

PLoS One 2018 5;13(9):e0203571. Epub 2018 Sep 5.

Max Planck Institute for Psycholinguistics, Nijmegen, The Netherlands.

Listeners are known to use adjacent contextual speech rate in processing temporally ambiguous speech sounds. For instance, an ambiguous vowel between short /α/ and long /a:/ in Dutch sounds relatively long (i.e. Read More

View Article and Full-Text PDF
February 2019

Improving Color Constancy in an Ambient Light Environment Using the Phong Reflection Model.

IEEE Trans Image Process 2018 Apr;27(4):1862-1877

We present a physics-based illumination estimation approach explicitly designed to handle natural images under ambient light. Existing physics-based color constancy methods are theoretically perfect but do not handle real-world images well because the majority of these methods assume a single illuminant. Therefore, specular pixels selected using existing methods produce estimated dichromatic lines that are thick or curvilinear in the presence of ambient light, thus generating significant errors. Read More

View Article and Full-Text PDF

An Update on the Sociomicrobiology of Quorum Sensing in Gram-Negative Biofilm Development.

Pathogens 2017 Oct 21;6(4). Epub 2017 Oct 21.

School of Life Sciences, University of Nevada, Las Vegas Box MS 454004 4505 S. Maryland Parkway, Las Vegas, NV 89154, USA.

Bacteria are social creatures that are able to interact and coordinate behaviors with each other in a multitude of ways. The study of such group behaviors in microbes was coined "sociomicrobiology" in 2005. Two such group behaviors in bacteria are quorum sensing (QS) and biofilm formation. Read More

View Article and Full-Text PDF
October 2017

Stability of medicines after repackaging into multicompartment compliance aids: eight criteria for detection of visual alteration.

Drugs Ther Perspect 2017 26;33(10):487-496. Epub 2017 Jul 26.

Pharmaceutical Care Research Group, University of Basel, Klingelbergstrasse 50, 4056 Basel, Switzerland.

Introduction: Multicompartment compliance aids (MCA) are widely used by patients. They support the management of medication and reduce unintentional nonadherence. MCA are filled with medicines unpacked from their original packaging. Read More

View Article and Full-Text PDF

Cupriavidus necator H16 Uses Flavocytochrome Sulfide Dehydrogenase To Oxidize Self-Produced and Added Sulfide.

Appl Environ Microbiol 2017 Nov 31;83(22). Epub 2017 Oct 31.

State Key Laboratory of Microbial Technology, Shandong University, Jinan, People's Republic of China

Production of sulfide (HS, HS, and S) by heterotrophic bacteria during aerobic growth is a common phenomenon. Some bacteria with sulfide:quinone oxidoreductase (SQR) and persulfide dioxygenase (PDO) can oxidize self-produced sulfide to sulfite and thiosulfate, but other bacteria without these enzymes release sulfide into the medium, from which HS can volatilize into the gas phase. Here, we report that H16, with the and genes encoding flavocytochrome sulfide dehydrogenases (FCSDs), also oxidized self-produced HS. Read More

View Article and Full-Text PDF
November 2017

Antimicrobial peptides for the control of biofilm formation.

Curr Top Med Chem 2017 Jan 5. Epub 2017 Jan 5.

Brandenburg Centrum for Regenerative Therapies, Faculty of Charité University, Augustenburger Platz 1, 13353 Berlin, Germany.

Antimicrobial peptides (AMPs) are an abundant and varied group of molecules recognized as the most ancient components of the innate immune system. They are found in a wide group of organisms including bacteria, plants and animals as a defense mechanism against different kinds of infectious pathogens. Over the past two decades, a fast-growing number of AMPs have been identified/designed and their wide-spectrum antimicrobial activity has been deeply investigated. Read More

View Article and Full-Text PDF
January 2017

Exopolysaccharides promote Myxococcus xanthus social motility by inhibiting cellular reversals.

Mol Microbiol 2017 02 19;103(4):729-743. Epub 2016 Dec 19.

Department of Biology, Texas A&M University, College Station, TX, 77843, USA.

The biofilm-forming bacterium Myxococcus xanthus moves on surfaces as structured swarms utilizing type IV pili-dependent social (S) motility. In contrast to isolated cells that reverse their moving direction frequently, individual cells within swarms rarely reverse. The regulatory mechanisms that inhibit cellular reversal and promote the formation of swarms are not well understood. Read More

View Article and Full-Text PDF
February 2017

Physiological and Perceptual Sensory Attenuation Have Different Underlying Neurophysiological Correlates.

J Neurosci 2016 10;36(42):10803-10812

Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, London WC1N 3BG, United Kingdom, and.

Sensory attenuation, the top-down filtering or gating of afferent information, has been extensively studied in two fields: physiological and perceptual. Physiological sensory attenuation is represented as a decrease in the amplitude of the primary and secondary components of the somatosensory evoked potential (SEP) before and during movement. Perceptual sensory attenuation, described using the analogy of a persons' inability to tickle oneself, is a reduction in the perception of the afferent input of a self-produced tactile sensation due to the central cancellation of the reafferent signal by the efference copy of the motor command to produce the action. Read More

View Article and Full-Text PDF
October 2016

The perception of self in birds.

Neurosci Biobehav Rev 2016 Oct 25;69:1-14. Epub 2016 Jul 25.

Laboratoire Ethologie Cognition Développement, LECD EA3456, Université Paris Ouest Nanterre La Défense, 200 avenue de la République, F92001 Nanterre cedex, France.

The perception of self is an important topic in several disciplines such as ethology, behavioral ecology, psychology, developmental and cognitive neuroscience. Self-perception is investigated by experimentally exposing different species of animals to self-stimuli such as their own image, smell or vocalizations. Here we review more than one hundred studies using these methods in birds, a taxonomic group that exhibits a rich diversity regarding ecology and behavior. Read More

View Article and Full-Text PDF
October 2016

The modulation of motor contagion by intrapersonal sensorimotor experience.

Neurosci Lett 2016 06 2;624:42-6. Epub 2016 May 2.

Faculty of Kinesiology and Physical Education, University of Toronto, Toronto, ON, M5S 2W6, Canada; Centre for Motor Control, University of Toronto, Toronto, ON, M5S 2W6, Canada. Electronic address:

Sensorimotor experiences can modify the internal models for action. These modifications can govern the discrepancies between predicted and actual sensory consequences, such as distinguishing self- and other-generated actions. This distinction may also contribute toward the inhibition of movement interference, which is strongly associated with the coupling of observed and executed actions. Read More

View Article and Full-Text PDF

Cohesion and Joint Speech: Right Hemisphere Contributions to Synchronized Vocal Production.

J Neurosci 2016 04;36(17):4669-80

Institute of Cognitive Neuroscience, University College London, London WC1N 3AR, United Kingdom,

Unlabelled: Synchronized behavior (chanting, singing, praying, dancing) is found in all human cultures and is central to religious, military, and political activities, which require people to act collaboratively and cohesively; however, we know little about the neural underpinnings of many kinds of synchronous behavior (e.g., vocal behavior) or its role in establishing and maintaining group cohesion. Read More

View Article and Full-Text PDF

Cortical subnetwork dynamics during human language tasks.

Neuroimage 2016 07 2;135:261-72. Epub 2016 Apr 2.

Department of Neurology, Johns Hopkins University, 600 N. Wolfe St., Meyer 2-161, Baltimore, MD 21287, USA.

Language tasks require the coordinated activation of multiple subnetworks-groups of related cortical interactions involved in specific components of task processing. Although electrocorticography (ECoG) has sufficient temporal and spatial resolution to capture the dynamics of event-related interactions between cortical sites, it is difficult to decompose these complex spatiotemporal patterns into functionally discrete subnetworks without explicit knowledge of each subnetwork's timing. We hypothesized that subnetworks corresponding to distinct components of task-related processing could be identified as groups of interactions with co-varying strengths. Read More

View Article and Full-Text PDF