32,338 results match your criteria group delay

Stress-induced alterations in HPA-axis reactivity and mesolimbic reward activation in individuals with emotional eating.

Appetite 2021 Sep 22:105707. Epub 2021 Sep 22.

Division of Women's Health, Department of Medicine; 75 Francis St., Boston, MA, 02115, USA; Department of Psychiatry; Brigham and Women's Hospital, 75 Francis St., Boston, MA, 02115, USA; Harvard Medical School, 25 Shattuck St., Boston, MA, 02115, USA; Innovation Center on Sex Differences in Medicine; Massachusetts General Hospital, 55 Fruit St., Boston, MA, 02114, USA. Electronic address:

Background: Emotional eating has emerged as a contributing factor to overeating, potentially leading to obesity or disordered eating behaviors. However, the underlying biological mechanisms related to emotional eating remain unclear. The present study examined emotional, hormonal, and neural alterations elicited by an acute laboratory stressor in individuals with and without emotional eating. Read More

View Article and Full-Text PDF
September 2021

How do primary care doctors compare to dentists in the referral of oral cancer?

Satish Kumar

Evid Based Dent 2021 Jan;22(3):94-95

Arizona School of Dentistry and Oral Health, A. T. Still University, Arizona, USA.

Data sources The authors searched electronic databases of Medline, Embase, Web of Science, Scopus, CINAHL and Google Scholar until May 2019. They also searched within the reference lists of studies, citation indexes and related articles from these electronic databases. Ongoing studies were searched in Research Registry, and Electronic Theses Online Service was used for searching theses. Read More

View Article and Full-Text PDF
January 2021

The Impact of Insurance Provider on Postoperative Hospital Length of Stay Following Spine Surgery.

World Neurosurg 2021 Sep 21. Epub 2021 Sep 21.

UT Southwestern, Department of Neurological Surgery; UT Southwestern, Department of Orthopedic Surgery.

Objective: Differences in insurer and payer status have been shown to increase patient hospital LOS by delaying the approval of transfer to a rehabilitation facility. The aim of the current study is to determine the impact of the type of insurance provider on postoperative hospital length of stay (LOS) after spine surgery.

Methods: In our single institution retrospective study, all patients undergoing elective spine surgery between August 2018 and August 2019 as part of an Enhanced Recovery After Surgery (ERAS) protocol were enrolled into a prospectively collected registry. Read More

View Article and Full-Text PDF
September 2021

Identification of embolic stroke in patients with large vessel occlusion: The Chinese embolic stroke score, CHESS.

CNS Neurosci Ther 2021 Sep 24. Epub 2021 Sep 24.

Department of Neurology, National Center for Neurological Disorders, National Clinical Research Centre for Aging and Medicine, Huashan Hospital, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China.

Aims: The aim of the study was to develop a simple and objective score using clinical variables and quantified perfusion measures to identify embolic stroke with large vessel occlusions.

Methods: Eligible patients from five centers participating in the International Stroke Perfusion Imaging Registry were included in this study. Patients were split into a derivation cohort (n = 213) and a validation cohort (n = 116). Read More

View Article and Full-Text PDF
September 2021

Few X-ray and PUVA treatments accelerate photocarcinogenesis in hairless mice.

Photochem Photobiol Sci 2021 Sep 24. Epub 2021 Sep 24.

Department of Dermatology, D92, Copenhagen University Hospital, Nielsine Nielsensvej 17, Entrance 9, 2400, Copenhagen, Denmark.

PUVA is a treatment that combines oral methoxypsoralen (8-MOP) with ultraviolet radiation A (UVA). It is used for severe psoriasis and the early stages of T-cell lymphoma. X-rays are an effective treatment for skin cancers. Read More

View Article and Full-Text PDF
September 2021

Adult-onset Still's disease or systemic-onset juvenile idiopathic arthritis and spondyloarthritis: overlapping syndrome or phenotype shift?

Rheumatology (Oxford) 2021 Sep 24. Epub 2021 Sep 24.

Centre d'Etude et de Référence sur les Maladies AutoInflammatoires et les Amyloses (CEREMAIA), FAI2R network, Paris, France.

Objectives: Systemic-onset juvenile idiopathic arthritis (SJIA) and adult-onset Still's disease (AOSD) are the same sporadic systemic auto-inflammatory disease. Spondyloarthritis (SpA) is a group of inflammatory non-autoimmune disorders. We report the observations of eight patients with SJIA/AOSD who also presented features of SpA during their disease evolution and estimate the prevalence of SpA in SJIA/AOSD. Read More

View Article and Full-Text PDF
September 2021

Predictors of periodontal and caries related perinatal oral healthcare, investigation of dentists' practices: a cross-sectional study.

PeerJ 2021 1;9:e12080. Epub 2021 Sep 1.

School of Dentistry, Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad, Pakistan.

Background: The objectives of the study were to assess the knowledge, attitude, and practice of dentists towards providing oral health care to pregnant women and to identify barriers and predictors of periodontal and caries related perinatal oral healthcare practices.

Methods: A cross-sectional analytical survey was conducted on dentists by using a random sampling technique, and a pre-validated questionnaire was delivered to 350 dentists from May 2018 to October 2018. Data were analyzed by utilizing SPSS software. Read More

View Article and Full-Text PDF
September 2021

Effect of Restricted Feeding on Metabolic Health and Sleep-Wake Rhythms in Aging Mice.

Front Neurosci 2021 7;15:745227. Epub 2021 Sep 7.

Department of Physiology, School of Basic Medical Sciences, Anhui Medical University, Hefei, China.

Aging, an irreversible and unavoidable physiological process in all organisms, is often accompanied by obesity, diabetes, cardiovascular diseases, sleep disorders, and fatigue. Thus, older adults are more likely to experience metabolic symptoms and sleep disturbances than are younger adults. Restricted feeding (RF) is a dietary regimen aimed at improving metabolic health and extending longevity, as well as reorganizing sleep-wake cycles. Read More

View Article and Full-Text PDF
September 2021

Predictors of institutionalization in users of day care facilities with mild cognitive impairment to moderate dementia.

BMC Health Serv Res 2021 Sep 24;21(1):1009. Epub 2021 Sep 24.

Department of Medical Psychology and Medical Sociology, University Clinic for Psychiatry and Psychotherapy, Erlangen University Hospital, Friedrich-Alexander University Erlangen Nuremberg, Erlangen, Germany, Schwabachanlage 6, 91054, Erlangen, Germany.

Background: Most people with dementia wish to remain at home for as long as possible. Therefore, it is important to know the predictors of institutionalization, especially those that can be influenced. The aim of the present study is to identify predictors of the institutionalization of people with mild cognitive impairment (MCI) to moderate dementia who attend day care facilities (DCFs) throughout Germany. Read More

View Article and Full-Text PDF
September 2021

Health-Related Stigma, Social Support, Self-Efficacy, and Self-Care Actions Among Adults With Sickle Cell Disease in Oman.

Clin Nurs Res 2021 Sep 24:10547738211046731. Epub 2021 Sep 24.

Sultan Qaboos University, Muscat, Sultanate of Oman.

Stigma contributes to the burden of individuals and families affected by Sickle cell disease (SCD) and causes delay in appropriate care seeking. The aim of this study is to examine the levels and associations between stigma, social support, self-efficacy, and self-care actions among adult patients with SCD in Oman using a cross-sectional, correlational design. Of the 264 participants, 56. Read More

View Article and Full-Text PDF
September 2021

Coherent Raman scattering imaging with a near-infrared achromatic metalens.

APL Photonics 2021 Sep 14;6(9):096107. Epub 2021 Sep 14.

John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA.

Miniature handheld imaging devices and endoscopes based on coherent Raman scattering are promising for label-free optical diagnosis. Toward the development of these small-scale systems, a challenge arises from the design and fabrication of achromatic and high-end miniature optical components for both pump and Stokes laser wavelengths. Here, we report a metasurface converting a low-cost plano-convex lens into a water-immersion, nearly diffraction-limited and achromatic lens. Read More

View Article and Full-Text PDF
September 2021

Case Report: A Boy From a Consanguineous Family Diagnosed With Congenital Muscular Dystrophy Caused by Integrin Alpha 7 () Mutation.

Front Genet 2021 6;12:706823. Epub 2021 Sep 6.

Department of Neurology, First Affiliated Hospital of Kunming Medical University, Kunming Medical University, Kunming, China.

Congenital muscular dystrophy (CMD) is a group of early-onset disorders with clinical and genetic heterogeneity. Patients always present with muscle weakness typically from birth to early infancy, delay or arrest of gross motor development, and joint and/or spinal rigidity. There are various genes related to the development of CMD. Read More

View Article and Full-Text PDF
September 2021

Getting the MOST out of follow-up: a randomized controlled trial comparing 3 monthly nurse led follow-up via telehealth, including monitoring CA125 and patient reported outcomes using the MOST (Measure of Ovarian Symptoms and Treatment concerns) with routine clinic based or telehealth follow-up, after completion of first line chemotherapy in patients with epithelial ovarian cancer.

Int J Gynecol Cancer 2021 Sep 22. Epub 2021 Sep 22.

Prince of Wales Clinical School, University of New South Wales, Randwick, New South Wales, Australia.

Background: Physical symptoms, anxiety, depression, fear of recurrence, sexual dysfunction, and social withdrawal are common in women after treatment for ovarian cancer. Most patients would like and need help dealing with these symptoms. The traditional model of follow-up care is unstructured and largely focused on diagnosing recurrent disease, and most oncologists lack skills to identify and manage psychosocial issues. Read More

View Article and Full-Text PDF
September 2021

Feasibility of Point-of-Care Ultrasound for Diagnosing Hypertrophic Pyloric Stenosis in the Emergency Department.

Pediatr Emerg Care 2021 Sep 7. Epub 2021 Sep 7.

From the Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine, Seoul Department of Emergency Medicine, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam Department of Emergency Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

Objectives: This study aimed to investigate the feasibility of point-of-care ultrasound (POCUS) for diagnosing hypertrophic pyloric stenosis (HPS) in the emergency department (ED).

Methods: A retrospective study was conducted in infants aged younger than 90 days who were brought to the ED due to vomiting between January 2015 and December 2019. Of these, infants who were clinically suspected of having HPS and underwent ultrasound were included and categorized into 3 groups: POCUS only, POCUS followed by radiologist-performed ultrasound (RADUS), and RADUS only. Read More

View Article and Full-Text PDF
September 2021

An empirical study of affective and cognitive functions in Compulsive Sexual Behavior Disorder.

J Behav Addict 2021 Sep 22. Epub 2021 Sep 22.

1Institute of Psychology, Polish Academy of Sciences, Warsaw, Poland.

Background And Aims: Despite the inclusion of the Compulsive Sexual Behavior Disorder (CSBD) in the International Classification of Diseases, very little is known about the underlying affective and cognitive processes. To fill this gap, we compared CSBD subjects and Healthy-Controls (HC) across negative/positive valence, cognitive and sensorimotor systems, as proposed by the Research Domain Criteria framework.

Methods: 74 heterosexual CSBD and 66 matched HC males were studied with 10 questionnaires and 8 behavioral tasks. Read More

View Article and Full-Text PDF
September 2021

Unilateral mimicking bilateral BPPV- a forgotten entity? Characteristics of a large cohort of patients, comparison with posterior canal BPPV and clinical implications.

J Otol 2021 Oct 20;16(4):252-257. Epub 2021 Jun 20.

The Faculty of Health Public, Ben Gurion University of the Negev, Beer, Sheva, Israel.

Objective: Unilateral mimicking bilateral benign paroxysmal positional vertigo (umb-BPPV) was attributed to inappropriate head positioning during testing of the posterior canal. Despite its inclusion in the Diagnostic criteria for the classification of vestibular disorders of the Bárány Society, the clinical characteristics and treatment responsiveness of this BPPV subtype have not been intensively studied.

Methods: Records of patients with BPPV seen at a single outpatient dizziness clinic during the years 2000-2020 were reviewed. Read More

View Article and Full-Text PDF
October 2021

High-efficiency broadband achromatic metalens for near-IR biological imaging window.

Nat Commun 2021 Sep 21;12(1):5560. Epub 2021 Sep 21.

State Key Laboratory on Tunable laser Technology, Ministry of Industry and Information Technology Key Lab of Micro-Nano Optoelectronic Information System, Harbin Institute of Technology (Shenzhen), Shenzhen, 518055, P. R. China.

Over the past years, broadband achromatic metalenses have been intensively studied due to their great potential for applications in consumer and industry products. Even though significant progress has been made, the efficiency of technologically relevant silicon metalenses is limited by the intrinsic material loss above the bandgap. In turn, the recently proposed achromatic metalens utilizing transparent, high-index materials such as titanium dioxide has been restricted by the small thickness and showed relatively low focusing efficiency at longer wavelengths. Read More

View Article and Full-Text PDF
September 2021

Ang-(1-7) protects skeletal muscle function in aged mice.

BMC Musculoskelet Disord 2021 Sep 21;22(1):809. Epub 2021 Sep 21.

The Center of Gerontology and Geriatrics, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Sichuan, China.

Background: The angiotensin-converting enzyme 2 (ACE2)/angiotensin 1-7 (Ang-(1-7)) axis has been shown to protect against the age-associated decline in skeletal muscle function. Here, we investigated the protective effects of ACE2 in mitigating the age-associated decline of skeletal muscle function and to identify the potential underlying molecular mechanisms.

Methods: We measured the expression levels of Ang-(1-7) in C57BL/6J mice of different ages and correlated these levels with measures of skeletal muscle function. Read More

View Article and Full-Text PDF
September 2021

Isometric exercise during immobilization reduces the time to return to play after lateral ankle sprain.

Phys Ther Sport 2021 Sep 8;52:168-172. Epub 2021 Sep 8.

Health and Sports Association Nabeshima Orthopaedic Clinic, 4-23-2 Matsunami, Chuo-ku, Chiba, Chiba, 260-0044, Japan.

[Objectives] Immobilization reduces symptoms after lateral ankle sprain but may worsen the range of motion (ROM) of the ankle and delay return to play (RTP). We aimed to elucidate the correlation between ankle ROM and time to RTP following immobilization for lateral ankle sprain and investigated if isometric exercise during immobilization would increase ROM and shorten the time to RTP. [Participants and outcome measures] Eighty-two patients with acute lateral ankle sprain were treated by a short-leg cast with or without isometric exercise and electrical muscle stimulation (EMS); intervention group or control group, respectively. Read More

View Article and Full-Text PDF
September 2021

Next Generation Strategies for Gene-Targeted Therapies of Central Nervous System Disorders: A Workshop Summary.

Mol Ther 2021 Sep 18. Epub 2021 Sep 18.

Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, PA 19104. Electronic address:

The National Institute of Neurological Disorders and Stroke (NINDS) held a workshop entitled, "Next Generation Strategies for Gene-Targeted Therapies of Central Nervous System (CNS) Disorders" in September 2019 in Bethesda, Maryland. The meeting brought together a multi-disciplinary group of experts in the field of CNS-directed gene-targeted therapy delivery from academia, industry, advocacy, and the government. The group was charged with identifying the key challenges and gaps in this evolving field, as well as suggesting potential solutions. Read More

View Article and Full-Text PDF
September 2021

Insights into the expanding phenotypic spectrum of inherited disorders of biogenic amines.

Nat Commun 2021 Sep 20;12(1):5529. Epub 2021 Sep 20.

University Children's Hospital Heidelberg, Dietmar-Hopp Metabolic Center, Heidelberg, Germany.

Inherited disorders of neurotransmitter metabolism are rare neurodevelopmental diseases presenting with movement disorders and global developmental delay. This study presents the results of the first standardized deep phenotyping approach and describes the clinical and biochemical presentation at disease onset as well as diagnostic approaches of 275 patients from the registry of the International Working Group on Neurotransmitter related Disorders. The results reveal an increased rate of prematurity, a high risk for being small for gestational age and for congenital microcephaly in some disorders. Read More

View Article and Full-Text PDF
September 2021

The impact of experimental pain on shoulder movement during an arm elevated reaching task in a virtual reality environment.

Physiol Rep 2021 Sep;9(18):e15025

Faculty of Medicine, Université Laval, Quebec City, Canada.

Background: People with chronic shoulder pain have been shown to present with motor adaptations during arm movements. These adaptations may create abnormal physical stress on shoulder tendons and muscles. However, how and why these adaptations develop from the acute stage of pain is still not well-understood. Read More

View Article and Full-Text PDF
September 2021

Discrepancy Between the Degree of Cognitive Impairment and Brain Imaging Abnormalities in Alzheimer's Disease Patients Is Associated with Cognitive Reserve.

J Alzheimers Dis 2021 Sep 10. Epub 2021 Sep 10.

Department of Geriatric Medicine, Tokyo Medical University, Tokyo, Japan.

Background: In Alzheimer's disease (AD) patients, the severity of cognitive impairment is thought to correlate with the degree of brain imaging abnormalities. However, some patients show only mild cognitive deficit, despite severe brain atrophy on magnetic resonance imaging (MRI) or marked hypoperfusion in the cerebral cortices on single-photon emission computed tomography (SPECT). This suggests that cognitive reserve (CR) can compensate for the clinical manifestations of AD in patients with extensive brain pathology. Read More

View Article and Full-Text PDF
September 2021

Cerebellar Activation Deficits in Schizophrenia During an Eyeblink Conditioning Task.

Schizophr Bull Open 2021 Jan 28;2(1):sgab040. Epub 2021 Aug 28.

Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN, USA.

The cognitive dysmetria theory of psychotic disorders posits that cerebellar circuit abnormalities give rise to difficulties coordinating motor and cognitive functions. However, brain activation during cerebellar-mediated tasks is understudied in schizophrenia. Accordingly, this study examined whether individuals with schizophrenia have diminished neural activation compared to controls in key regions of the delay eyeblink conditioning (dEBC) cerebellar circuit (eg, lobule VI) and cerebellar regions associated with cognition (eg, Crus I). Read More

View Article and Full-Text PDF
January 2021

Health-seeking behaviour among pregnant women during the COVID-19 pandemic: A qualitative study.

Heliyon 2021 Sep 10;7(9):e07972. Epub 2021 Sep 10.

Ministry of Health, Kisumu, Kenya.

Background: The novel coronavirus pandemic has killed millions of people globally while significantly destroying the social, economic, and political wellbeing of people. The global pandemic has negatively impacted pregnant women's access to prenatal care. The current study sought to understand the health-seeking behaviour of women who were pregnant during the onset of the COVID-19 pandemic in Kenya. Read More

View Article and Full-Text PDF
September 2021

Athletes With Anterior Shoulder Instability: A Prospective Study on Player Perceptions of Injury and Treatment.

Orthop J Sports Med 2021 Sep 15;9(9):23259671211032239. Epub 2021 Sep 15.

Columbia University Center for Shoulder, Elbow and Sports Medicine, New York, New York, USA.

Background: Many in-season athletes choose to delay or avoid surgery in order to continue playing and avoid downtime such as missed games or seasons.

Purpose: To learn about the attitudes toward the injury and treatment of in-season shoulder instability in competitive athletes who have suffered a shoulder dislocation.

Study Design: Cross-sectional study; Level of evidence, 3. Read More

View Article and Full-Text PDF
September 2021

The Effectiveness of Superficial Drain to Reduce Surgical Site Infection in Colorectal Surgery.

Cureus 2021 Aug 16;13(8):e17232. Epub 2021 Aug 16.

Department of Surgery, King Abdulaziz Medical City, Jeddah, SAU.

Background The incidence of surgical site infection (SSI) in colorectal surgery is high, which can complicate and delay postoperative recovery. This study mainly aims to evaluate the efficacy of subcutaneous drains in decreasing superficial surgical site infection in colorectal surgery patients.  Study design This is a retrospective cohort study that included patients over 16 years old who underwent colorectal surgery from the 1st of January 2015 till the 31st of December 2020. Read More

View Article and Full-Text PDF

Factors associated with non-adherence to antiretroviral therapy among HIV-infected adolescents aged 15-19 years: a snapshot from the Mother and Child Center in Yaounde, Cameroon.

Pan Afr Med J 2021 29;39:154. Epub 2021 Jun 29.

Department of Public Health, Faculty of Medicine and Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon.

Introduction: non-adherence to antiretroviral therapy (ART) constitutes the main cause of therapeutic failure among HIV-infected adolescents, especially in the aged group 15 to 19 years. We aimed to determine factors associated with this non-adherence in this specific population.

Methods: we conducted a cross-sectional study at the Mother and Child Center in Yaounde from August to October 2018. Read More

View Article and Full-Text PDF

Clinical Characteristics and Follow-Up of 19 Children With Hashimoto's Thyroiditis Aged Below 3 Years: A Single-Center Retrospective Analysis.

Front Endocrinol (Lausanne) 2021 3;12:737527. Epub 2021 Sep 3.

Department of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, China.

Aim: To analyze the clinical characteristics of Hashimoto's thyroiditis (HT) in children below 3 years of age in order to improve the understanding of the disease, avoid misdiagnosis, and achieve early diagnosis and treatment.

Methods: The study retrospectively analyzed the clinical data of 19 patients diagnosed with HT in the first three years of life.

Results: The patients (12 female, 7 male) had an average age of 26. Read More

View Article and Full-Text PDF
September 2021