29,800 results match your criteria granulomatous

[Granulomatous colitis in a French Bulldog puppy].

Tierarztl Prax Ausg K Kleintiere Heimtiere 2021 Jun 22;49(3):212-218. Epub 2021 Jun 22.

Klinikum Veterinärmedizin, Klinik für Kleintiere, Innere Medizin, Justus-Liebig-Universität Gießen.

A 6-month-old French bulldog was presented due to chronic large intestinal diarrhea of 4 months duration. The diagnostic procedures initiated by the referring veterinarian had resulted in a tentative diagnosis of chronic enteropathy, however treatment consisting of elimination diet as well as antibiotic, anthelmintic, anti-inflammatory and immunosuppressive medication had been unsuccessful. By means of endoscopy and histological examination, pronounced erosions and ulcerations of the colonic mucosa were detected. Read More

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Epidemiological characteristics and trends of Bacillus Calmette-Guérin lymphadenitis in Shanghai, China from 2010 to 2019.

Hum Vaccin Immunother 2021 Jun 22:1-6. Epub 2021 Jun 22.

Department of Immunization, Xuhui District Center for Disease Control and Prevention, Shanghai, China.

Although the administration of the Bacillus Calmette-Guérin (BCG) vaccine is generally safe, lymphadenitis, the most common complication of BCG vaccination, can occur. Here, we describe the epidemiological characteristics and incidence trends of BCG lymphadenitis in Shanghai, China, among a population with a high burden of tuberculosis. A total of 56 cases of adverse events following immunization (AEFI) after BCG vaccination were reported in Shanghai, including 51 cases of BCG lymphadenitis (91. Read More

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Wiad Lek 2021 ;74(4):832-837


Objective: The aim: To establish the dynamics of reparation processes in periapical tissues in chronic granulomatous periodontitis under the influence of the developed composition based on calcium hydroxyapatite in comparison with the generally accepted drug MTA.

Patients And Methods: Materials and methods: The main group included 52 individuals, and the comparison group - 19 patients with chronic granulomatous periodontitis. In the first experimental subgroup, patients were obturated of the tooth root apical area with the proposed composition, and in the second experimental subgroup patients were performed obturation of the root canal apical area with additional transcanal withdrawal of the composition into the periapical area. Read More

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January 2021

SARS-CoV-2 Myocarditis Due to Severe Obesity.

Cureus 2021 May 17;13(5):e15074. Epub 2021 May 17.

Internal Medicine, Chicago Medical School Internal Medicine Residency Program at Northwestern Medicine McHenry Hospital, McHenry, USA.

Myocarditis is defined as a myocardial injury concomitant with myocardial dysfunction. Several causes are associated with it, including infectious versus inflammatory and inherited cardiomyopathies. It can be acute, subacute, or chronic, and it can present as focal versus diffuse myocardial dysfunction. Read More

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Local Steroid Treatment: An Effective Procedure for Idiopathic Granulomatous Mastitis, Including Complicated Cases.

J Invest Surg 2021 Jun 21:1-7. Epub 2021 Jun 21.

Department of General Surgery, Kocaeli University School of Medicine, Kocaeli, Türkiye.

Purpose: To evaluate the effectiveness of treatment with topical and intralesional steroids for idiopathic granulomatous mastitis (IGM) and to compare with surgical methods.

Methods: Data were retrospectively collected from records. Intralesional steroid injection and topical steroid administration, hereafter referred to as local steroid treatment (LST) were applied in Group 1. Read More

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Granulomatous Mucormycosis of the Temporal Bone extending Into Temporomandibular Joint and Infratemporal Fossa: A Case Report.

Ear Nose Throat J 2021 Jun 21:1455613211022079. Epub 2021 Jun 21.

ENT institute and Department of Otolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, China.

Mucormycosis of temporal bone is extremely rare. They are usually associated with host immunodeficiency, are difficult to diagnose, and many cases are fatal. We performed a literature review and found only 10 reported cases of temporal bone mucormycosis. Read More

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infection in a non-cystic fibrosis patient: an arcane presentation.

Access Microbiol 2021 15;3(4):000222. Epub 2021 Apr 15.

Department of Microbiology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.

Introduction: is an aerobic, Gram-negative bacillus, which exhibits innate resistance to multiple antibiotics and disinfectants. Although it is a chronic colonizer of the respiratory tract, it may rarely present with fatal necrotizing pneumonia-like features in immunosuppressed individuals, as those with chronic granulomatous disease, or patients with significant pulmonary compromise, like cystic fibrosis.

Case Presentation: A 76-year-old male presented with complaints of breathlessness, cough with mucoid expectoration and fever for 3 days. Read More

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Rapid visual field progression in a patient with glaucoma as the presenting manifestation of sarcoidosis.

Am J Ophthalmol Case Rep 2021 Sep 5;23:101132. Epub 2021 Jun 5.

Department of Ophthalmology, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada.

Purpose: To report a case of accelerated visual field progression secondary to a new orbital apex lesion in a patient with a longstanding history of fatigue and cough.

Observations: A 73-year-old myopic female with known open angle glaucoma presented with accelerated unilateral visual field progression. Maximally tolerated medical therapy was instituted over a period of 1-2 years with imminent discussions of surgical intervention. Read More

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September 2021

Molecular characterization and histo-physiological alterations induced by concurrent helminthosis in the liver of urban commensal rodents in Punjab, India.

Iran J Vet Res 2021 ;22(1):15-223

Department of Veterinary Parasitology, College of Veterinary Science, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana-141004, India.

Background: Rodents harbour a number of parasites of public health importance, thus, they threaten human health and livestock.

Aims: The present study aimed to characterize two helminthic species found in commensal rodents and record histo-physiological alterations induced by them.

Methods: A total of 300 synanthropic rodents of three species: (n=201), Bandicota bengalensis Mus musculus and necropsied in different seasons during November 2017 to October 2019 at Ludhiana, Punjab, India. Read More

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January 2021

Biomarkers of non-infectious inflammatory CNS diseases in dogs - Where are we now? Part I: Meningoencephalitis of unknown origin.

Vet J 2021 Jul 16;273:105678. Epub 2021 Apr 16.

Copenhagen University, Department of Veterinary Clinical Sciences, Dyrlægevej 16, DK-1870 Frederiksberg C, Denmark. Electronic address:

Meningoencephalitides of Unknown Origin (MUO) comprises a group of non-infectious inflammatory brain conditions, which frequently cause severe neurological disease and death in dogs. Although multiple diagnostic markers have been investigated, a conclusive diagnosis, at present, essentially relies on postmortem histopathology. However, different groups of biomarkers, e. Read More

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Retrospective study of phaeohyphomycosis in aquarium-housed fish, with first descriptions of Exophiala lecanii-corni and Neodevriesia cladophorae in fish.

J Fish Dis 2021 Jun 20. Epub 2021 Jun 20.

Department of Pathology, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.

A broadening fish host range is affected by novel and known pigmented fungal pathogens. A review of 2,250 piscine submissions received by the Aquatic Pathology Service, University of Georgia, revealed 47 phaeohyphomycosis cases (2.1%), representing 34 bony and cartilaginous fish species. Read More

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Granulomatous lung disease and immune reconstitution inflammatory syndrome in Whipple's disease.

BMJ Case Rep 2021 Jun 18;14(6). Epub 2021 Jun 18.

Institute of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland.

We present the case of a 70-year-old woman with a history of seronegative arthritis, recurrent pleural effusion and weight loss. A prior lung biopsy had revealed non-caseating epithelioid cell granulomas without evidence for microbial organisms on special stains. Intestinal biopsy findings where suspicious for Whipple's disease, which was confirmed by PCR testing, both on the intestinal and retrospectively on the lung tissue. Read More

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A Comprehensive Review of Sarcoidosis Treatment for Pulmonologists.

Pulm Ther 2021 Jun 18. Epub 2021 Jun 18.

UOC Malattie Respiratorie, Immunology, Allergy, Rare Respiratory Diseases and Lung Transplant Laboratory, Dip. Scienze Mediche, Chirurgiche e Neuroscienze, Università di Siena Policlinico "Le Scotte", Siena, Italy.

Due to frequent lung involvement, the pulmonologist is often the reference physician for management of sarcoidosis, a systemic granulomatous disease with a heterogeneous course. Treatment of sarcoidosis raises some issues. The first challenge is to select patients who are likely to benefit from treatment, as sarcoidosis may be self-limiting and remit spontaneously, in which case treatment can be postponed and possibly avoided without any significant impact on quality of life, organ damage or prognosis. Read More

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A correlation of Mycobacterium bovis SB0134 infection between cattle and a wild boar (Sus Scrofa) in Campania region.

Vet Anim Sci 2021 Sep 29;13:100182. Epub 2021 May 29.

Istituto Zooprofilattico Sperimentale del Mezzogiorno, Department of Animal Health, Unit of Virology, Portici, Naples, Italy.

A case of infection is described in a death adult female wild boar in the province of Avellino, Campania Region (Southern Italy). The carcass was sent to the Istituto Zooprofilattico Sperimentale del Mezzogiorno (IZSM) of Portici, Naples, Italy, where postmortem examination was performed. At necropsy, a disseminated granulomatous infection was observed, with involvement of various lymph node districts, spleen and lungs. Read More

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September 2021

Sarcoid-like granulomatous myositis-associated hypercalcemia. An infrequent case to consider.

Medicina (B Aires) 2021 ;81(3):462-466

Departamento de Endocrinología, Escuela de Medicina, Pontificia Universidad Católica de Chile, Chile. E-mail:

PTH-independent hypercalcemia due to granulomatous disease is well-documented and sarcoidosis is the most characteristic disease, although there are others. We describe a case of sarcoid-like granulomatous myositis. An 87-year-old man was referred with tetraparesis and hypercalcemia (albumin-corrected calcium of 13. Read More

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Free Living Amoebic Infections: Review.

J Clin Microbiol 2021 Jun 16:JCM0022821. Epub 2021 Jun 16.

Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA.

Infections caused by , spp., and result in a variety of clinical manifestations in humans. These amoebae are found in water and soil worldwide. Read More

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Differential diagnosis of uncommon prostate diseases: combining mpMRI and clinical information.

Insights Imaging 2021 Jun 16;12(1):79. Epub 2021 Jun 16.

Department of Radiology, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing, 100034, China.

The differential diagnosis of abnormalities in the prostate is broad, covering common (acinar adenocarcinoma, benign prostatic hyperplasia, chronic prostatitis, hemorrhage, cysts, calcifications, atrophy and fibrosis) and less common conditions (tumors other than acinar adenocarcinoma, granulomatous prostatitis containing tuberculosis, abscesses and other conditions, and idiopathic disorders such as amyloidosis and exophytic benign prostatic hyperplasia). Recent advances in magnetic resonance imaging (MRI) of the prostate gland and imaging guidelines, such as the Prostate Imaging Reporting and Data System version 2.1 (PI-RADS v2. Read More

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Integrated transcriptomic analysis of human tuberculosis granulomas and a biomimetic model identifies therapeutic targets.

J Clin Invest 2021 Jun 15. Epub 2021 Jun 15.

School of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, Southampton, United Kingdom.

Tuberculosis (TB) is a persistent global pandemic and standard treatment has not changed for thirty years. Mycobacterium tuberculosis (Mtb) has undergone prolonged co-evolution with humans, and patients can control Mtb even after extensive infection, demonstrating the fine balance between protective and pathological host responses within infected granulomas. We hypothesised that whole transcriptome analysis of human TB granulomas isolated by laser capture microdissection could identify therapeutic targets, and that comparison with a non-infectious granulomatous disease, sarcoidosis, would identify disease-specific pathological mechanisms. Read More

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Is vaccination a viable method to control Johne's disease caused by Mycobacterium avium subsp. paratuberculosis? Data from 12 million ovine vaccinations and 7.6 million carcass examinations in New South Wales, Australia from 1999-2009.

PLoS One 2021 14;16(6):e0246411. Epub 2021 Jun 14.

James J. Peters VAMC, Bronx, New York, United States of America.

Background: Mycobacterium avium subsp. paratuberculosis (MAP) causes Johne's disease (or paratuberculosis), a chronic wasting disease of ruminants and other animals resulting from granulomatous enteritis. There are increasing concerns that MAP is zoonotic. Read More

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Clinical variants of mycosis fungoides in a cohort.

Gac Med Mex 2021 ;157(1):41-46

Centro Dermatológico "Dr. Ladislao de la Pascua", Mexico City, Mexico.

Introduction: Mycosis fungoides (MF) is the most common primary skin T-cell lymphoma, which is characterized for a heterogeneous clinical expressivity.

Objective: To report clinical variants and sociodemographic characteristics in patients with MF under the care of a dermatological hospital.

Methods: 290 patients with MF clinical and histopathological diagnosis attended to over the course of 11 years were included. Read More

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January 2021

"Post Coronavirus Disease (COVID-19) Reactivation of a Quiescent Unilateral Anterior Uveitis".

SN Compr Clin Med 2021 Jun 7:1-5. Epub 2021 Jun 7.

Department of Neuro-ophthalmology, Cornea and Refractive Surgery, Narayana Nethralaya, Bangalore, India.

Coronavirus disease (COVID-19) can be associated with ophthalmic manifestations like conjunctivitis, retinal haemorrhages, retinal vascular occlusions, papillophlebitis, and Adie's syndrome. We herein report for a case of a unilateral acute anterior uveitis which was quiescent for 13 years and was reactivated post COVID-19 infection in a 43-year-old Asian Indian male. He had a past history of recurrent unilateral granulomatous anterior and intermediate uveitis in the right eye (RE), and all the investigations done 14 years ago were negative and had been on treatment with topical and oral steroids. Read More

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Invasive Mediastinal Mucormycosis with Pulmonary and Cardiac Involvement in an Adult with Chronic Granulomatous Disease: Case Report and Review of the Literature.

Eur J Case Rep Intern Med 2021 5;8(5):002435. Epub 2021 May 5.

Department of Critical Care Medicine at King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.

Mucormycosis is a rare fungal infection that often causes rhinocerebral disease. However, there have been rare cases of mediastinal involvement. These patients remain a therapeutic challenge and mortality in this group is very high. Read More

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Adolescent with severe granulomatosis with polyangiitis: a case report.

Pan Afr Med J 2021 18;38:285. Epub 2021 Mar 18.

Department of Respiratory Diseases, Hospital 20 Août 1953, University of Hassan II, University Hospital Center Ibn Rochd, Casablanca, Morocco.

Granulomatosis with polyangiitis (GPA) is a rare vasculitis among adolescents. Its pulmonary manifestations may mimic tuberculosis. We report the case of a 16-years-old female patient with multiple excavated lung nodules revealed by a chronic cough, hemoptysis, epistaxis and weight loss. Read More

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Oesophageal Obstruction in a Donkey Due to Mediastinal Lymphadenitis Caused by Mycobacterium avium Complex.

J Comp Pathol 2021 May 25;185:66-71. Epub 2021 May 25.

Department of Pathobiology and Population Sciences, Royal Veterinary College, Hatfield, Hertfordshire, UK.

Mycobacterial infections are rare in horses, donkeys and mules. Although there are a few reports in horses, mycobacterial disease is poorly documented in the donkey. Mycobacterial infection of equine species typically affects the alimentary tract, causing granulomatous enterocolitis resulting in diarrhoea and chronic weight loss, while lymph nodes and liver may also be affected. Read More

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Frequency of detection and load of amastigotes in the pancreas of Leishmania infantum-seropositive dogs: clinical signs and histological changes.

Parasit Vectors 2021 Jun 12;14(1):321. Epub 2021 Jun 12.

Laboratório de Pesquisa Clínica em Dermatozoonoses em Animais Domésticos, Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Av. Brasil, 4365, Rio de Janeiro, RJ, 21040-360, Brazil.

Background: Zoonotic visceral leishmaniasis is caused by the protozoan Leishmania infantum and is highly lethal in humans and dogs if left untreated. The frequency of this parasite and associated histological changes in the pancreas of dogs are poorly studied. Therefore, the objectives of this study were to evaluate the frequency of detection and load of amastigotes in the pancreas of L. Read More

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Interstitial granuloma annulare triggered by Lyme disease.

Dermatol Online J 2021 May 15;27(5). Epub 2021 May 15.

Division of Dermatology, The Ohio State University Wexner Medical Center, Columbus, OH.

Granuloma annulare is a non-infectious granulomatous skin condition with multiple different associations. We present a case of a man in his 60s with a three-week history of progressive targetoid plaques on his arms, legs, and trunk. Skin biopsy demonstrated interstitial granuloma annulare. Read More

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Macroscopic identification of visceral titanium pigment in an intravenous drug user.

J Forensic Sci 2021 Jun 12. Epub 2021 Jun 12.

Forensic Science SA, Adelaide, SA, Australia.

Autopsy findings in intravenous drug addicts are quite variable and may involve a number of organ systems. Reports of the macroscopic identification at autopsy of components of tablets that have been crushed and injected are, however, exceedingly rare. The case of 34-year-old man who died of zolpidem toxicity on a background of pulmonary hypertension attributed to intravenous injections of crushed tablets is described. Read More

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Extirpation of Recurrent Petrous Apex Cholesterol Granuloma Through the Zygomatic Approach: 2-Dimensional Operative Video.

Oper Neurosurg (Hagerstown) 2021 Jun 10. Epub 2021 Jun 10.

Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Petrous apex cholesterol granulomas are believed to result from blockage of the normal aeration of the petrous air cells, resulting in a repetitive cycle of mucosal engorgement, hemorrhage, and granuloma formation.1 The lesion usually progressively expands causing compressive symptoms. The thick granulomatous wall envelopes various ages of breakdown products, including a cholesterol-containing fluid, which is typically hyperintense on T1 and T2 weighted magnetic resonance imaging. Read More

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A Conservative Management Approach for Unusual Presentation of Oral Actinomycosis.

Qamar Hashem

Case Rep Dent 2021 18;2021:5570758. Epub 2021 May 18.

Clinical Dental Sciences Department/Endodontic Division College of Dentistry, Princes Noura Bint Abdulrahman University, Riyadh, Saudi Arabia.

Actinomycosis is gram-positive saprophytic infection that is characterized by chronic suppurative and granulomatous lesion. It could be found in the oral cavity, lungs, colon, and genital area. In the oral cavity, it is commonly associated with infected root canals presented as persistent infections. Read More

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Cryopyrin-associated periodic syndrome: a treatable genetic inflammatory condition.

Pract Neurol 2021 Jun 10. Epub 2021 Jun 10.

Department of Neurology, Royal Hobart Hospital, Hobart, Tasmania, Australia

A 20-year-old man presented with recurrent subdural haemorrhages on a background of progressive sensorineural hearing loss, juvenile idiopathic arthritis and intracranial hypertension of unknown cause. His mother had a similar previous history. They both had a persistently mildly elevated serum C reactive protein. Read More

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