34,093 results match your criteria grafted


An eco-friendly NP flame retardant for durable flame-retardant treatment of cotton fabric.

Int J Biol Macromol 2021 Jul 24. Epub 2021 Jul 24.

Institute of Bioorganic and Medicinal Chemistry, College of Chemistry and Chemical Engineering, Southwest University, No. 2 Tiansheng Street, Chongqing 400715, China. Electronic address:

A halogen-free, formaldehyde-free, efficient, durable, NP flame retardant, the ammonium salt of meglumine phosphoric ester acid (ASMPEA), was prepared. The Fourier-transform infrared spectroscopy (FTIR) and nuclear magnetic resonance spectroscopy (H NMR, C NMR, and P NMR) results indicated that ASMPEA was grafted onto cotton fibers by P-O-C covalent bonds. The LOI value of 30 wt% ASMPEA-treated cotton fabric was 40. Read More

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Improved intestinal absorption and oral bioavailability of astaxanthin via poly (ethylene glycol)-graft-chitosan nanoparticle: preparation, in vitro evaluation and pharmacokinetics in rats.

J Sci Food Agric 2021 Jul 26. Epub 2021 Jul 26.

Department of Pharmaceutics, School of Pharmacy, Center for Nano Drug/Gene Delivery and Tissue Engineering, Jiangsu University, Zhenjiang, 212013, China.

Background: Astaxanthin (ASTA) is a kind of food-derived active ingredients (FDAI) with functions of antioxidant, antidiabetic, and nontoxicity, but its poor solubility and low bioavailability hinder further application in food industry. In this study, a novel carrier, polyethylene glycol grafted chitosan (PEG-g-CS), was applied in enhancing bioavailability of astaxanthin firstly. It encapsulated astaxanthin completely by solvent evaporation to manufacture ASTA-PEG-g-CS nanoparticle for improving absorption. Read More

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Grafting of CAG peptides and (polyethylene glycol) on unsaturated polyurethane films to promote selective adhesion and migration of urethral epithelial cells.

J Mater Chem B 2021 Jul 27. Epub 2021 Jul 27.

Department of Polymer Science and Engineering, MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Zhejiang University, Hangzhou 310027, China.

Selective adhesion and migration of urethral epithelial cells (HUCs) over fibroblasts (FIBs) are very important in the reconstruction of the urethral epithelial layer and prevention of ureteral scarring and stenosis. In this study, unsaturated polyurethane (PPFU-CO-SS) films were co-grafted with a cell-resisting poly(ethylene glycol) (PEG) layer and HUC-selective Cys-Ala-Gly (CAG) peptides, whose physicochemical changes were confirmed by X-ray photon spectroscopy, fluorescence spectroscopy and water contact angle measurements. The adhesion and activation of platelets on the PEG/CAG grafted surface were significantly reduced compared to those on the PPFU-CO-SS, resulting in a similar status as that on a PEG-grafted surface. Read More

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Liquid Crystalline Properties of Symmetric and Asymmetric End-Grafted Cellulose Nanocrystals.

Biomacromolecules 2021 Jul 23. Epub 2021 Jul 23.

Department of Materials Science & Engineering, Universitat Politècnica de Catalunya Av. Eduard Maristany 16, 08019 Barcelona, Spain.

The hydrophilic polymer poly[2-(2-(2-methoxy ethoxy)ethoxy)ethylacrylate] (POEGA) was grafted onto the reducing end-groups (REGs) of cellulose nanocrystal (CNC) allomorphs, and their liquid crystalline properties were investigated. The REGs on CNCs extracted from cellulose I (CNC-I) are exclusively located at one end of the crystallite, whereas CNCs extracted from cellulose II (CNC-II) feature REGs at both ends of the crystallite, so that grafting from the REGs affords asymmetrically and symmetrically decorated CNCs, respectively. To confirm the REG modification, several complementary analytical techniques were applied. Read More

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Efficient Design to Monitor the Site-specific Sustained Release of Non-Emissive Anti-Cancer Drug.

Chem Asian J 2021 Jul 23. Epub 2021 Jul 23.

Indian Institute of Science Education and Research Kolkata, Polymer Research Center,, Department of Chemical Sciences, 741246, Mohanpur, INDIA.

A pH-responsive smart nano-carrier with significant components was synthesized by conjugating the non-emissive anticancer drug methyl orange and polyethylene glycol derived folate moiety to the backbone of polynorbornene. Complete synthesis procedure and characterization methods of three monomers included in the work: norbornene-derived Chlorambucil (Monomer 1), norbornene grafted with polyethylene glycol, and folic acid (Monomer 2)  and norbornene attached methyl orange (Monomer 3) connected to the norbornene backbone through ester linkage were clearly discussed. Finally, the random copolymer CHO PEG FOL METH was synthesized by ring-opening metathesis polymerization (ROMP) using Grubbs' second-generation catalyst. Read More

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Bio-inspired dual-functional phospholipid-poly(acrylic acid) brushes grafted porous poly(vinyl alcohol) beads for selective adsorption of low-density lipoprotein.

J Mater Chem B 2021 Jul 23. Epub 2021 Jul 23.

School of Ophthalmology & Optometry, Eye Hospital, School of Biomedical Engineering, Wenzhou Medical University, Wenzhou, Zhejiang 325027, China.

Elevated levels of low-density lipoproteins (LDL) are recognized as a crucial indicator of hyperlipidemia (HLP) and lowering of LDL levels represents an effective clinical treatment strategy. Inspired by the conjugation of phospholipid monolayers and the lipid content of the LDL particle, the current study describes the preparation of an innovative hemoperfusion adsorbent. The adsorbent was prepared by attachment of phosphatidyl ethanolamine to poly(acrylic acid) modified poly(vinyl alcohol-co-triallyl isocyanurate) beads ([email protected]). Read More

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Functionalization of Aminoalkylsilane-Grafted Bacterial Nanocellulose with ZnO-NPs-Doped Pullulan Electrospun Nanofibers for Multifunctional Wound Dressing.

ACS Biomater Sci Eng 2021 Jul 23. Epub 2021 Jul 23.

Microbiological Engineering and Industrial Biotechnology Group, College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620, China.

High moisture permeability, excellent mechanical properties in a wet state, high water-holding capability, and high exudate absorption make bacterial nanocellulose (BNC) a favorable candidate for biomedical device production, especially wound dressings. The lack of antibacterial activity and healing-promoting ability are the main drawbacks that limit its wide application. Pullulan (Pul) is a nontoxic polymer that can promote wound healing. Read More

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Thermally-modulated cell separation columns using a thermoresponsive block copolymer brush as a packing material for the purification of mesenchymal stem cells.

Biomater Sci 2021 Jul 23. Epub 2021 Jul 23.

Faculty of Pharmacy, Keio University, 1-5-30 Shibakoen, Minato, Tokyo 105-8512, Japan.

Cell therapy using mesenchymal stem cells (MSCs) is used as effective regenerative treatment. Cell therapy requires effective cell separation without cell modification and cellular activity reduction. In this study, we developed a temperature-modulated mesenchymal stem cell separation column. Read More

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Chitosan grafted butein: A metal-free transducer for electrochemical genosensing of exosomal CD24.

Carbohydr Polym 2021 Oct 15;269:118333. Epub 2021 Jun 15.

Electrodics and Electrocatalysis Division, CSIR-Central Electrochemical Research Institute (CECRI), Karaikudi 630 003, Tamil Nadu, India; Academy of Scientific & Innovative Research (AcSIR), Ghaziabad 201 002, India. Electronic address:

Metal-free cost-efficient biocompatible molecules are beneficial for opto-electrochemical bioassays. Herein, chitosan (CS) conjugated butein is prepared via graft polymerization. Structural integrity between radical active sites of CS and its probable conjugation routes with reactive OH group of butein during grafting were comprehensively studied using optical absorbance/emission property, NMR, FT-IR and XPS analysis. Read More

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October 2021

Spatio-temporal control over destabilization of Pickering emulsions stabilized by light-sensitive dextran-based nanoparticles.

Carbohydr Polym 2021 Oct 27;269:118261. Epub 2021 May 27.

Laboratoire de Chimie des Polymères Organiques, Univ. Bordeaux, CNRS, Bordeaux INP, UMR 5629, Bordeaux, 16 Avenue Pey-Berland, F-33607 Pessac, France. Electronic address:

The implementation of light-sensitive Pickering emulsions with spatio-temporal responsiveness in advanced applications like drug-delivery, colloidal or reaction engineering would open new avenues. However, curiously, light-sensitive Pickering emulsions are barely studied in the literature and their biocompatibility and/or degradability scarcely addressed. Thus, their development remains a major challenge. Read More

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October 2021

Hierarchical Vitalization of Oligotyrosine in Mitigating Islet Amyloid Polypeptide Amyloidogenesis through Multivalent Macromolecules with Conformation-Restrained Nanobody Ligands.

ACS Nano 2021 Jul 23. Epub 2021 Jul 23.

National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.

The development of inhibitors that can effectively mitigate the amyloidogenesis of human islet amyloid polypeptide (hIAPP), which is linked to type II diabetes, remains a great challenge. Oligotyrosines are intriguing candidates in that they can block the hIAPP aggregation through multiplex phenol-hIAPP interactions. However, oligotyrosines containing too many tyrosine units (larger than three) may fail to inhibit amyloidogenesis due to their increased hydrophobicity and strong self-aggregation propensity. Read More

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Immobilization of lipase on β-cyclodextrin grafted and aminopropyl-functionalized chitosan/FeO magnetic nanocomposites: An innovative approach to fruity flavor esters esterification.

Food Chem 2021 Jul 17;366:130616. Epub 2021 Jul 17.

State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China; Jiangxi Province Key Laboratory of Edible and Medicinal Resources Exploitation, Nanchang University, Nanchang 330031, China; New Zealand Institute of Natural Medicine Research, 8Ha Crescent, Auckland 2104, New Zealand.

The lipase from Bacillus licheniformis NCU CS-5 was immobilized onto β-cyclodextrin (CD) grafted and aminopropyl-functionalized chitosan-coated FeO magnetic nanocomposites (FeO-CTS-APTES-GA-β-CD). Fourier transform infrared spectroscopy, thermogravimetry analysis, X-ray diffraction, scanning electron microscopy and transmission electron microscopy showed that not only the functionalized magnetic nanoparticles were synthesized but also the immobilized lipase was successfully produced. The immobilized lipase exhibited higher optimal pH value (10. Read More

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Development of a natamycin-based non-migratory antimicrobial active packaging for extending shelf-life of yogurt drink (Doogh).

Food Chem 2021 Jul 16;366:130606. Epub 2021 Jul 16.

Department of Food Science and Technology, School of Agriculture, Shiraz University, Shiraz 71441-65186, Iran; Department of Biological Sciences, School of Natural Science, University of Limerick, Limerick, Ireland. Electronic address:

A natamycin-based non-migratory antimicrobial packaging for extending shelf-life of yogurt drink (Doogh) was developed. Firstly, the surface of low-density polyethylene film (LDPE) was modified with acrylic acid at different times of UV exposure (0-10 min) to produce carboxylic functional groups. Then, natamycin was applied to the UV-treated films to bind covalently with the pendent functional groups. Read More

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Endochondral Bone Tissue Engineering Using Human Induced Pluripotent Stem Cells.

Tissue Eng Part A 2021 Jul 26. Epub 2021 Jul 26.

Kobe University Graduate School of Medicine, Department of Orthopaedic Surgery, Kobe, Japan;

There has been great interest in the use of induced pluripotent stem cells (iPSCs) in bone regenerative strategies for bone defects. In the present study, we investigated whether the implantation of chondrogenically differentiated iPSC-derived mesenchymal stem cells (iMSCs) could lead to the successful regeneration of bone defects in nude mice. Two clones of human iPSCs (201B7 and 454E2) were used. Read More

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[Diagnosis and management of fat necrosis after autologous fat transplantation of breast].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2021 Jul;35(7):918-922

The 18th Department of Plastic Surgery, Plastic Surgery Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100144, P.R.China.

Objective: To review the diagnosis and management of fat necrosis after autologous fat transplantation of breast.

Methods: Based on the latest related literature, the pathology, clinical and radiographic examinations, influence factors, as well as the management of fat necrosis after autologous fat transplantation for breast augmentation and reconstruction were summarized.

Results: Fat necrosis after breast autologous fat transplantation is histologically manifested as hyaline degeneration, fibrosis, and calcification. Read More

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[Effectiveness of limited middle and posterior column osteotomy via transvertebral space approach for old thoracolumbar compression fracture].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2021 Jul;35(7):868-872

Department of Orthopedics, Affiliated Hospital of Hebei University, Baoding Hebei, 071000, P.R.China.

Objective: To investigate the effectiveness of limited middle and posterior column osteotomy via transvertebral space approach in treatment of old thoracolumbar compression fracture.

Methods: A clinical data of 47 patients with old thoracolumbar compression fractures, who met the selection criteria between January 2010 and March 2018, was retrospectively analyzed. Twenty-five patients (group A) underwent the limited middle and posterior column osteotomy via transvertebral space approach, and 22 patients (group B) underwent the pedicle subtraction osteotomy (PSO). Read More

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Clinical application of individualized total arterial coronary artery bypass grafting in coronary artery surgery.

World J Clin Cases 2021 Jul;9(19):5073-5081

Second Ward, Department of Heart and Great Arteries Surgery, Fourth Affiliated Hospital of Harbin Medical University, Harbin 150001, Heilongjiang Province, China.

Background: Total arterial revascularization is associated with increased patency and long-term efficacy and decreased perioperative morbidity and mortality and incidence of cardiac-related events and sternal wound infection compared with conventional coronary artery bypass surgery (CABG), in which the left internal mammary artery (LIMA) is typically grafted to the left anterior descending artery with additional saphenous vein grafts often used. This study determined whether these favorable clinical results could be realized at the authors' institute.

Aim: To summarize the early efficacy and clinical experience of individualized total arterial coronary artery bypass grafting surgery. Read More

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Surface-Grafted Poly(ionic liquid) that Lubricates in Both Non-polar and Polar Solvents.

ACS Macro Lett 2021 Jul 28;10(7):907-913. Epub 2021 Jun 28.

School of Chemical Engineering, University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom.

We show that a surface-grafted polymer brush, 1--butyl-3-vinyl imidazolium bromide-based poly(ionic liquids), is able to reduce the interfacial friction by up to 66% and 42% in dodecane and water, respectively. AFM-based force spectroscopy reveals that the polymer brush adopts distinctively different interfacial conformations: swollen in water but collapsed in dodecane. Minimal surface adhesion was observed with both polymer conformations, which can be attributed to steric repulsion as the result of a swollen conformation in water or surface solvation when the hydrophobic fraction of the polymer was exposed to the dodecane. Read More

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Super absorbent chitosan-based hydrogel sponges as carriers for caspofungin antifungal drug.

Int J Pharm 2021 Jul 22:120925. Epub 2021 Jul 22.

Laboratory of Polymer Chemistry and Technology, Department of Chemistry, Aristotle University of Thessaloniki, Thessaloniki. Electronic address:

Novel chitosan copolymers (CS-g-SBMA) grafted with [2-(methacryloyloxy)ethyl]dimethyl-(3-sulfopropyl)ammonium hydroxide (SBMA) in various molar ratio 1.5:1, 5:1, 11.5:1 and 20:1, were synthesized in the present study. Read More

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Synthesis and characterization of chitosan/polyacrylamide hydrogel grafted poly(N-methylaniline) for methyl red removal.

Int J Biol Macromol 2021 Jul 22. Epub 2021 Jul 22.

Department of Chemistry, Faculty of Science, Polymer Research Laboratory, Beni-Suef University, 62514 Beni-Suef City, Egypt. Electronic address:

Chitosan/polyacrylamide hydrogel grafted poly(N-methylaniline) (CS/PACM-gr-PNMA) was good synthesized by chemical oxidative radical polymerization using potassium persulphate (KPS). The obtained polymer samples are characterized using IR and Uv-visible spectroscopy. Both surface properties and thermal stability were studied using XRD, SEM, BET and TGA techniques respectively. Read More

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Polyethylene/Polyamide Blends Made of Waste with Compatibilizer: Processing, Morphology, Rheological and Thermo-Mechanical Behavior.

Polymers (Basel) 2021 Jul 20;13(14). Epub 2021 Jul 20.

Department of Interdisciplinary Dentistry, Pomeranian Medical University, 70-111 Szczecin, Poland.

The aim of this study was to develop a polyethylene/polyamide (R-PE/R-PA) regranulated product made from post-consumer wastes grafted with polyethylene-graft-maleic anhydride (PE-g-MAH) by reactive extrusion in a twin-screw extruder equipped with an external mixing zone. The compatibility effect of PE-g-MAH used as a modifier in R-PE/R-PA blends was evaluated by means of differential scanning calorimetry (DSC) and dynamic mechanical thermal analysis (DMTA), while the analysis of the chemical structure of this blend was carried out by Fourier transform infrared spectroscopy (FT-IR). The thermal properties, complex viscosity, and selected usage properties of R-PE/R-PA blends compatibilized with PE-g-MAH, i. Read More

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Surface Modification of Polyurethane Membrane with Various Hydrophilic Monomers and N-Halamine: Surface Characterization and Antimicrobial Properties Evaluation.

Polymers (Basel) 2021 Jul 15;13(14). Epub 2021 Jul 15.

Department of Chemical Engineering, National Cheng Kung University, Tainan 70101, Taiwan.

Reducing microbial infections associated with biomedical devices or articles/furniture noted in a hospital or outpatient clinic remains a great challenge to researchers. Due to its stability and low toxicity, the N-halamine compound has been proposed as a potential antimicrobial agent. It can be incorporated into or blended with the FDA-approved biomaterials. Read More

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Structure/Properties Relationship of Anionically Synthesized Diblock Copolymers "" Chemically Modified Graphene.

Polymers (Basel) 2021 Jul 14;13(14). Epub 2021 Jul 14.

Department of Materials Science Engineering, University Campus-Dourouti, University of Ioannina, 45110 Ioannina, Greece.

A novel approach to obtaining nanocomposite materials using anionic sequential polymerization and post-synthetic esterification reactions with chemically modified graphene sheets (CMGs) is reported. The anionically synthesized diblock copolymer precursors of the PS--PI-OH type were grafted to the chemically modified -COOH groups of the CMGs, giving rise to the final composite materials, namely polystyrene--poly(isoprene)--CMGs, which exhibited enhanced physicochemical properties. The successful synthesis was determined through multiple molecular characterization techniques together with thermogravimetric analysis for the verification of increased thermal stability, and the structure/properties relationship was justified through transmission electron microscopy. Read More

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Interactions between Sterically Stabilized Nanoparticles: The Effects of Brush Bidispersity and Chain Stiffness.

Authors:
Sergei A Egorov

Polymers (Basel) 2021 Jul 13;13(14). Epub 2021 Jul 13.

Department of Chemistry, University of Virginia, Charlottesville, VA 22901, USA.

Density Functional Theory is employed to study structural properties and interactions between solvent-free polymer-grafted nanoparticles. Both monodisperse and bidisperse polymer brushes with variable chain stiffness are considered. The three major control parameters are the grafting density, the grafted chain length, and its stiffness. Read More

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Enhanced Osteogenesis of Dental Pulp Stem Cells In Vitro Induced by Chitosan-PEG-Incorporated Calcium Phosphate Cement.

Polymers (Basel) 2021 Jul 9;13(14). Epub 2021 Jul 9.

Department of Biosystems Engineering, Seoul National University, Seoul 08826, Korea.

The use of bone graft materials is required for the treatment of bone defects damaged beyond the critical defect; therefore, injectable calcium phosphate cement (CPC) is actively used after surgery. The application of various polymers to improve injectability, mechanical strength, and biological function of injection-type CPC is encouraged. We previously developed a chitosan-PEG conjugate (CS/PEG) by a sulfur (VI) fluoride exchange reaction, and the resulting chitosan derivative showed high solubility at a neutral pH. Read More

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Preparation of Colored Microcapsule Phase Change Materials with Colored SiO Shell for Thermal Energy Storage and Their Application in Latex Paint Coating.

Materials (Basel) 2021 Jul 18;14(14). Epub 2021 Jul 18.

College of Materials Science and Engineering, Zhejiang University of Technology, Hangzhou 310000, China.

This article reports the design and manufacture of colored microcapsules with specific functions and their application in architectural interior wall coating. Utilizing reactive dyes grafted SiO shell to encapsulate paraffin through interfacial polymerization and chemical grafting methods, this experiment successfully synthesized [email protected] colored microcapsules. The observations of surface morphology demonstrated that the colored microcapsules had a regular spherical morphology and a well-defined core-shell structure. Read More

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The Synthesis of Poly(Vinyl Alcohol) Grafted with Fluorinated Protic Ionic Liquids Containing Sulfo Functional Groups.

Molecules 2021 Jul 8;26(14). Epub 2021 Jul 8.

Faculty of Chemistry, Nicolaus Copernicus University in Toruń, 7 Gagarina Street, 87-100 Toruń, Poland.

There has been an ongoing need to develop polymer materials with increased performance as proton exchange membranes (PEMs) for middle- and high-temperature fuel cells. Poly(vinyl alcohol) (PVA) is a highly hydrophilic and chemically stable polymer bearing hydroxyl groups, which can be further altered. Protic ionic liquids (proticILs) have been found to be an effective modifying polymer agent used as a proton carrier providing PEMs' desirable proton conductivity at high temperatures and under anhydrous conditions. Read More

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DNA-Grafted 3D Superlattice Self-Assembly.

Int J Mol Sci 2021 Jul 15;22(14). Epub 2021 Jul 15.

Shenzhen Research Institute of Nanjing University, Shenzhen 518000, China.

The exploitation of new methods to control material structure has historically been dominating the material science. The bottom-up self-assembly strategy by taking atom/molecule/ensembles in nanoscale as building blocks and crystallization as a driving force bring hope for material fabrication. DNA-grafted nanoparticle has emerged as a "programmable atom equivalent" and was employed for the assembly of hierarchically ordered three-dimensional superlattice with novel properties and studying the unknown assembly mechanism due to its programmability and versatility in the binding capabilities. Read More

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Optomechanic Coupling in Ag Polymer Nanocomposite Films.

J Phys Chem C Nanomater Interfaces 2021 Jul 30;125(27):14854-14864. Epub 2021 Jun 30.

Max Planck Institute for Polymer Research, Ackermannweg 10, Mainz 55128, Germany.

Particle vibrational spectroscopy has emerged as a new tool for the measurement of elasticity, glass transition, and interactions at a nanoscale. For colloid-based materials, however, the weakly localized particle resonances in a fluid or solid medium renders their detection difficult. The strong amplification of the inelastic light scattering near surface plasmon resonance of metallic nanoparticles (NPs) allowed not only the detection of single NP eigenvibrations but also the interparticle interaction effects on the acoustic vibrations of NPs mediated by strong optomechanical coupling. Read More

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Topical cationic hairy particles targeting cell free DNA in dermis enhance treatment of psoriasis.

Biomaterials 2021 Jul 15;276:121027. Epub 2021 Jul 15.

School of Materials Science and Engineering, Key Laboratory for Polymeric Composite and Functional Materials of Ministry of Education, GD Research Center for Functional Biomaterials Engineering and Technology, Sun Yat-sen University, 510275, Guangzhou, China. Electronic address:

Abnormal high level of cell free DNA (cfDNA) triggers chronic inflammation to exacerbate psoriasis symptoms. Scavenging cfDNA by topical cationic polymeric nanoparticles has been certified as an effective therapeutic strategy for treating psoriasis. However, cationic cfDNA scavengers have a great potential risk to organs after entering systemic circulation through skin barrier. Read More

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