Invest Radiol 2021 Mar 5. Epub 2021 Mar 5.
From the Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine Department of Clinical Innovative Medicine, Institute for Advancement of Clinical and Translational Science, Kyoto University Hospital National Hospital Organisation, Kyoto Medical Center Kyoto-Katsura Hospital Department of Biomedical Statistics and Bioinformatics, Kyoto University Graduate School of Medicine, Kyoto, Japan Siemens Healthcare K.K., Tokyo, Japan Siemens Healthcare GmbH, Erlangen, Germany Department of Breast Surgery, Kyoto University Graduate School of Medicine, Kyoto, Kyoto, Japan.
Introduction: The aim of this study was to investigate the variation of apparent diffusion coefficient (ADC) values with diffusion time according to breast tumor type and prognostic biomarkers expression.
Materials And Methods: A total of 201 patients with known or suspected breast tumors were prospectively enrolled in this study, and 132 breast tumors (86 malignant and 46 benign) were analyzed. Diffusion-weighted imaging scans with 2 diffusion times were acquired on a clinical 3-T magnetic resonance imaging scanner using oscillating and pulsed diffusion-encoding gradients (effective diffusion times, 4. Read More