191 results match your criteria goat fascioliasis


The First Report of Ruminant Fascioliasis in Sabah, East Malaysia.

J Parasitol Res 2021 16;2021:6691483. Epub 2021 Apr 16.

Department of Pathology and Microbiology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400 UPM Serdang Selangor, Malaysia.

Ruminant fascioliasis is a neglected yet important tropical zoonotic disease that affects both the livestock and humans. The disease has a worldwide distribution, and Malaysia is one of the countries that face problems related to this parasite. These retrospective studies were conducted in Makmal Diagnosa Veterinar Kota Kinabalu (MDVKK) and Sabah Meat Technology Centre (SMTC), Kinarut over a period of eleven years (2008-2018). Read More

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Evaluation of zoonotic platyhelminthe infections identified in slaughtered livestock in Iran, 2015-2019.

BMC Vet Res 2021 May 5;17(1):185. Epub 2021 May 5.

Department of Parasitology and Mycology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Background: Platyhelminth infections of livestock can result in considerable economic losses. This study aims to evaluate the spatial frequency of cystic echinococcosis (CE), dicrocoeliasis, and fascioliasis in livestock slaughtered in Iran during the years 2015-2019 and estimate direct costs associated with organ condemnation due to these parasites.

Methods: Abattoir data from 413 abattoirs representing all 31 Iranian provinces were collected from the Iran Veterinary Organization. Read More

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Vaccination with cathepsin L mimotopes of Fasciola hepatica in goats reduces worm burden, morphometric measurements, and reproductive structures.

Microb Pathog 2021 Jun 9;155:104859. Epub 2021 Apr 9.

Facultad de Medicina Veterinaria y Zootecnia, Benemérita Universidad Autónoma de Puebla, Tecamachalco, Puebla, Mexico.

Fasciolosis is a worldwide emergent zoonotic disease that significantly constrains the productivity of livestock. We conducted an experimental trial with four groups of five goats each, vaccinated with 1 × 10 phage particles of cathepsin L1 (CLI: DPWWLKQ), CL1 (SGTFLFS), and CL2 (PPIRNGK) mimotopes combined with Quil A adjuvant. Animals received a booster four weeks later. Read More

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Induced Hepatic Abscess Treated with Triclabendazole.

Korean J Gastroenterol 2021 01;77(1):39-44

Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea.

Fascioliasis is a zoonotic disease caused by that infects mainly cattle, sheep, and goats. Humans can be infected by water or aquatic plants contaminated with metacercariae. The authors encountered two cases of infection. Read More

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January 2021

Prevalence and distribution of livestock schistosomiasis and fascioliasis in Côte d'Ivoire: results from a cross-sectional survey.

BMC Vet Res 2020 Nov 17;16(1):446. Epub 2020 Nov 17.

Unité de Formation et de Recherche Biosciences, Université Félix Houphouët-Boigny, 22 BP 770 Abidjan 22, Abidjan, Côte d'Ivoire.

Background: Schistosoma and Fasciola are zoonotic parasites of public health and veterinary importance. However, while the epidemiology of schistosomiasis in humans is well studied, little is known about fascioliasis and schistosomiasis in livestock in Côte d'Ivoire. This study aimed to determine the prevalence and the distribution of livestock schistosomiasis and fascioliasis across Côte d'Ivoire. Read More

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November 2020

Milk As a New Diagnostic Tool for Rapid Detection of Fascioliasis in Dairy Goats Using Excretory/Secretory Antigen.

Acta Parasitol 2021 Jun 29;66(2):336-345. Epub 2020 Sep 29.

Parasitology Departments, Faculty of Veterinary Medicine, Cairo University, P.O Box 12211, Giza, Egypt.

Purpose: Fascioliasis is a serious livestock illness of particular importance for dairy goats; the objectives of this study were to describe effects of F. gigantica on milk composition and to use this information to estimate economic damages linked with Fasciola spp. infections. Read More

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Initial assessment of the economic burden of major parasitic helminth infections to the ruminant livestock industry in Europe.

Prev Vet Med 2020 Sep 26;182:105103. Epub 2020 Jul 26.

Ghent University, Faculty of Veterinary Medicine, Laboratory of Parasitology, Salisburylaan 133, 9820, Merelbeke, Belgium.

We report a European wide assessment of the economic burden of gastrointestinal nematodes, Fasciola hepatica (common liver fluke) and Dictyocaulus viviparus (bovine lungworm) infections to the ruminant livestock industry. The economic impact of these parasitic helminth infections was estimated by a deterministic spreadsheet model as a function of the proportion of the ruminant population exposed to grazing, the infection frequency and intensity, the effect of the infection on animal productivity and mortality and anthelmintic treatment costs. In addition, we estimated the costs of anthelmintic resistant nematode infections and collected information on public research budgets addressing helminth infections in ruminant livestock. Read More

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September 2020

Cysts and parasites in an abattoir in Northwest Ethiopia; an urgent call for action on "one health".

J Infect Dev Ctries 2020 06 29;14(6.1):53S-57S. Epub 2020 Jun 29.

Department of Internal Medicine, University of Gondar, Gondar, Ethiopia.

Introduction: Zoonotic parasitic infections such as echinococcosis affect cattle, sheep and goats by lowering quality of meat and hides as well as decreasing milk production. The burden of such diseases among humans is usually underestimated as they are difficult to diagnose. We used abattoir data to estimate the prevalence of zoonotic parasitic infections in animals. Read More

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Molecular Confirmation of a Fasciola gigantica × Fasciola hepatica Hybrid in a Chadian Bovine.

J Parasitol 2020 04;106(2):316-322

Swiss Tropical and Public Health Institute, Socinstrasse 57, CH-4051 Basel, Switzerland.

Fascioliasis is a zoonotic infection of humans and, more commonly, ruminants. It is caused by 2 liver fluke species, Fasciola hepatica and Fasciola gigantica, which differ in size. The traditional morphological methods used to distinguish the 2 species can be unreliable, particularly in the presence of hybrids between the 2 species. Read More

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Status of fasciolosis among domestic ruminants in Iran based on abattoir data: a systematic review and meta-analysis

Ann Parasitol 2020 ;66(1):77–86

Infectious Diseases Research Centre, Golestan University of Medical Sciences; Shast Kolah Road, P.O Box: 4934174515, Gorgan, Iran

Fasciolosis is considered as an ongoing neglected zoonotic disease in tropical regions of the world, relating to notable financial and public health issues. The current systematic review and meta-analysis was planned to determine the status of fasciolosis among domestic ruminants, including cattle, buffalo, goat, and sheep at the industrial slaughterhouses in Iran, between the years 2000 and 2016. Eight databases, four English and four Persian, were searched. Read More

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Prevalence and economic impact of cystic echinococcosis and liver fluke infections in slaughtered sheep and goat in north-central Iran, 2008-2018.

J Parasit Dis 2020 Mar 26;44(1):17-24. Epub 2019 Nov 26.

6Student Research Committee, Kerman University of Medical Sciences, Kerman, Iran.

Cystic echinococcosis (CE) and liver fluke infections as important zoonotic infections impose a large socioeconomic impact on societies. As an endemic region for these infections, slaughterhouse inspections should be more considered in Iran. This study aimed to analyze the 11-year record of offal condemnation due to CE, fascioliasis, dicrocoeliasis infections in sheep and goat and its economic impact at Alborz slaughterhouse, north-central Iran. Read More

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A Scoping Review of the Prevalence of Fascioliasis in Malaysia and Risk Factors for Infection.

Malays J Med Sci 2020 Feb 27;27(1):22-36. Epub 2020 Feb 27.

School of Health Sciences, Universiti Sains Malaysia, Kelantan, Malaysia.

This review aimed to provide a comprehensive overview of ruminant and human fascioliasis in Malaysia and to identify research gaps in knowledge of the prevalence of fascioliasis in Malaysia and risk factors for the disease using available evidence-based data. We conducted a scoping review based on the framework of Arksey and O'Malley. The preferred reporting items for systematic reviews and meta-analyses were used to guide the review process. Read More

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February 2020

Genetic diversity and distribution of Fasciola hepatica haplotypes in Iran: Molecular and phylogenetic studies.

Vet Parasitol Reg Stud Reports 2020 01 4;19:100359. Epub 2019 Dec 4.

Department of Laboratory Sciences, Maragheh University of Medical Sciences, Maragheh, Iran. Electronic address:

Fasciolosis is a zoonotic disease caused by Fasciola hepatica and Fasciola gigantica. Over the last decade, diagnostic tools to detect and differentiate Fasciola species have improved, but our knowledge of the distribution of haplotypes and gene flow of this parasite is not comprehensive yet. The purpose of this study was to investigate this gap in the epidemiology of F. Read More

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January 2020

Genetic diversity and multiplicity of infection in Fasciola gigantica isolates of Pakistani livestock.

Parasitol Int 2020 Jun 8;76:102071. Epub 2020 Feb 8.

University of Edinburgh, Royal (Dick) School of Veterinary Studies and Roslin Institute, Easter Bush Veterinary Centre, Midlothian, Scotland EH25 9RG, UK. Electronic address:

Fasciola spp. are responsible for over 3 billion US dollars of production loss annually in livestock and cause widespread zoonotic disease. Nevertheless, understating of the emergence and spread of the trematode species is poor. Read More

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Multigene typing and phylogenetic analysis of Fasciola from endemic foci in Iran.

Infect Genet Evol 2020 06 21;80:104202. Epub 2020 Jan 21.

Laboratory of Veterinary Parasitology, Faculty of Agriculture, Iwate University, 3-18-8 Ueda, Morioka, Japan; Department of Pathogenic Veterinary Science, United Graduate School of Veterinary Science, Gifu University, Yanagido 1-1, Gifu 501-1193, Japan.

Fasciolosis is a public health problem originally transmitted from livestock. Although molecular analysis of the nuclear and mitochondrial genes allow discrimination between the two known species of Fasciola, F. hepatica and F. Read More

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The Multitasking Cathepsin B Interferes With Various Functions of Goat Peripheral Blood Mononuclear Cells .

Front Immunol 2019 23;10:1707. Epub 2019 Jul 23.

State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.

Cathepsin B, a lysosomal cysteine protease, is thought to be involved in the pathogenesis of infection, but its exact role remains unclear. In the present study, a recombinant cathepsin B (rFgCatB) protein was expressed in the methylotrophic yeast . Western blot analysis confirmed the reactivity of the purified rFgCatB protein to serum from -infected goats. Read More

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November 2020

Profiling circulating microRNAs in serum of Fasciola gigantica-infected buffalo.

Mol Biochem Parasitol 2019 09 1;232:111201. Epub 2019 Aug 1.

State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, CAAS, Lanzhou, 730046, Gansu, China.

Circulating miRNAs are stably existed in serum and plasma and can serve as a novel class of biomarkers for the diagnosis of helminthic infection. Fasciola gigantica, the causative agents of fascioliasis, live in the liver of in humans and ruminants, especially cattle, goat and sheep. In this study, a total of 121 host circulating miRNAs were differentially expressed (2 ≥ fold change, p < 0. Read More

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September 2019

Prevalence of fasciolosis in livestock and humans: A systematic review and meta-analysis in Iran.

Comp Immunol Microbiol Infect Dis 2019 Aug 11;65:116-123. Epub 2019 May 11.

Cellular and Molecular Research Center & Department of Medical Parasitology and Mycology, Urmia University of Medical Sciences, Urmia, Iran; Department of Medical Parasitology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

Fasciolosis is a re-emerging disease of livestock and rarely human, being endemic in Iran. Herein, we aimed to quantitatively assess the human seropositivity and prevalence of animal fasciolosis in our country. English and Persian databases were searched for online literature. Read More

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Immature Fasciola gigantica: Time-dependent ultrastructural changes following in vivo treatment with triclabendazole.

Acta Trop 2019 Aug 24;196:15-21. Epub 2019 Apr 24.

Section of Parasitology, Department of Zoology, Faculty of Life Sciences, Aligarh Muslim University, Aligarh 202 002, India.

An in vivo study was carried out to investigate the ultrastructural effects of triclabendazole (TCBZ) on immature Fasciola gigantica in a goat model. Five goats were infected with an oral gavage of 150 metacercarial cysts of F. gigantica and anthelmintic treatment occurred at 4 weeks post infection with an oral dose of 10 mg/kg. Read More

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Fasciola spp. in Armenia: Genetic diversity in a global context.

Vet Parasitol 2019 Apr 1;268:21-31. Epub 2019 Mar 1.

Department of Parasitology, University of Hohenheim, Stuttgart, Germany. Electronic address:

Fasciolosis, a food- and waterborne infection caused by the trematodes Fasciola hepatica and F. gigantica, is recognized by WHO as a neglected zoonotic disease. Whereas F. Read More

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Studies on the prevalence of fascioliasis among ruminant animals in northern Bauchi state, north-eastern Nigeria.

Parasite Epidemiol Control 2019 May 15;5:e00090. Epub 2019 Feb 15.

Biological Sciences Department, Federal University Dutse, Jigawa State, Nigeria.

A study of prevalence of ruminant fascioliasis was undertaken from May 2017 to April 2018. A set of 7640 stool and 7640 bile samples were collected from slaughtered cattles, sheeps and goats in seven local abattoirs located within the seven Local Government Areas making up northern Bauchi state. The Sample collection was demarcated into four sections of three months each corresponding into four local seasons. Read More

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Prevalence of Animal Fasciolosis and Specification of spp. Isolated from Sheep, Goats and Cattle by Molecular Method: Hamadan Province, West of Iran.

Iran J Parasitol 2018 Oct-Dec;13(4):524-531

Dept. of Parasitology and Mycology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.

Background: Fascioliasis is a common disease among humans and animals. Having global distribution, disease is developed by hepatic trematodes, and . The main objective of this research was determining the prevalence of species in Hamadan livestock and identifying those using PCR-RFLP. Read More

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January 2019

Risk factors for the presence of Fasciola hepatica antibodies in bulk-milk samples and their association with milk production decreases, in Cuban dairy cattle.

BMC Vet Res 2018 Nov 8;14(1):336. Epub 2018 Nov 8.

Kreavet, Hendrik Mertensstraat 17, 9150, Kruibeke, Belgium.

Background: Worldwide, Fasciola hepatica infection causes high production losses in the livestock industry. Recently, studies have analyzed the association between measurements of F. hepatica infection intensity and herd management practices. Read More

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November 2018

The pervasive effects of recombinant Fasciola gigantica Ras-related protein Rab10 on the functions of goat peripheral blood mononuclear cells.

Parasit Vectors 2018 Nov 6;11(1):579. Epub 2018 Nov 6.

State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province, 730046, People's Republic of China.

Background: Fasciola gigantica-induced immunomodulation is a major hurdle faced by the host for controlling infection. Here, we elucidated the role of F. gigantica Ras-related protein Rab10 (FgRab10) in the modulation of key functions of peripheral blood mononuclear cells (PBMCs) of goats. Read More

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November 2018

Human and Animal Fascioliasis in Iran: Systematic Review and Meta-analysis.

Infect Disord Drug Targets 2019 ;19(1):30-35

Department of Psychiatry, School of medicine, Ilam University of Medical Sciences, Ilam, Iran.

Objective: The aim of this study was to investigate the prevalence of fascioliasis in humans, cattle, sheep, and goats, done by a systematic review in Iran.

Methods: Fifty articles were extracted including Iranian papers such as Google scholar, Magiran, Iran Medex, SID, and Pubmed. Out of these, 21 articles were selected for meta-analysis. Read More

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Low allelic diversity in vaccine candidates genes from different locations sustain hope for Fasciola hepatica immunization.

Vet Parasitol 2018 Jul 11;258:46-52. Epub 2018 Jun 11.

Parasitology Unit, IRNASA-CSIC, Salamanca, Spain. Electronic address:

Fasciola hepatica is a trematode parasite that causes fasciolosis in animals and humans. Fasciolosis is usually treated with triclabendazole, although drug-resistant parasites have been described in several geographical locations. An alternative to drug treatment would be the use of a vaccine, although vaccination studies that have been performed mainly in ruminants over the last 30 years, show high variability in the achieved protection and are not yet ready for commercialisation. Read More

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Human case of Fasciola gigantica-like infection, review of human fascioliasis reports in Nepal, and epidemiological analysis within the South Central Asia.

Acta Parasitol 2018 Sep;63(3):435-443

Departamento de Parasitología, Facultad de Farmacia, Universidad de Valencia, Av. Vicent Andrés Estellés s/n, 46100 Burjassot, Valencia, Spain.

The diagnosis of a 22 year-old male patient from Kerabari, Morang District, Nepal led to the review of human fascioliasis cases and analysis of the epidemiological situation in that country not included in the WHO fascioliasis map. Symptom onset one month before egg detection and normal levels of ALT and AST did not agree with the 3-4-month migratory period of fascioliasis. A shorter acute phase may happen when the main biliary duct is reached by the migratory juveniles directly from the intestinal lumen. Read More

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September 2018

Purification of native Sigma class glutathione transferase from Fasciola hepatica.

Mol Biochem Parasitol 2018 06 27;222:45-50. Epub 2018 Apr 27.

Institute of Biological, Environmental and Rural Sciences (IBERS), Aberystwyth University, Aberystwyth SY23 3DA, UK. Electronic address:

Fascioliasis is a parasitic disease of grazing livestock and a threat to global food security by significantly reducing the production value of sheep, goats and cattle. Moreover, the zoonotic parasite is also a re-emerging food borne threat to human populations. Driven by climate change, the prevalence of fascioliasis is set to increase. Read More

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Prevalence of liver flukes infections and hydatidosis in slaughtered sheep and goats in Nishapour, Khorasan Razavi, Iran.

Vet World 2018 Feb 9;11(2):146-150. Epub 2018 Feb 9.

Department of Food Safety and Hygiene, School of Public Health, Zanjan University of Medical Sciences, Zanjan, Iran.

Background: Food-borne trematode infections and hydatidosis are endemic diseases caused by helminths in Iran that are responsible for great economic loss and getting public health at risk.

Aim: Aim of this study was to determine the prevalence of fasciolosis, dicrocoeliasis, and hydatidosis infections in slaughtered sheep and goats in Nishapour, Khorasan Razavi province of Iran.

Materials And Methods: A survey was implemented on 130,107 sheep and goats slaughtered at an abattoir in Nishapour (Neyshbur) city, north central Khorasan Razavi Province, Iran, to determine the prevalence of fascioliasis, dicrocoeliosis and presence of hydatidosis. Read More

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February 2018

A recombinant Fasciola gigantica 14-3-3 epsilon protein (rFg14-3-3e) modulates various functions of goat peripheral blood mononuclear cells.

Parasit Vectors 2018 03 6;11(1):152. Epub 2018 Mar 6.

State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province, 730046, People's Republic of China.

Background: The molecular structure of Fasciola gigantica 14-3-3 protein has been characterized. However, the involvement of this protein in parasite pathogenesis remains elusive and its effect on the functions of innate immune cells is unknown. We report on the cloning and expression of a recombinant F. Read More

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