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Inpatient Management and Treatment of a Giant Pancreatic Pseudocyst: A Case Report.

Cureus 2021 Nov 29;13(11):e19990. Epub 2021 Nov 29.

Internal Medicine, Riverside Regional Medical Center, Newport News, USA.

Pancreatic pseudocyst formation is a common sequela of pancreatitis caused by alcohol use or gallstones. Giant pancreatic pseudocyst is an infrequently reported but serious complication of pancreatitis. Due to the large volume of pancreatic fluid containing active enzymes, giant pancreatic pseudocysts may require surgical intervention. Read More

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November 2021

A Single-Center Study on the Outcomes of Target Limb Revascularization in Femoropopliteal Lesions Treated With Drug Coated Balloons and Bare Metal Stents.

J Endovasc Ther 2022 Jan 5:15266028211068772. Epub 2022 Jan 5.

Discipline of Radiology, St. Clare's Mercy Hospital, St. John's, NL, Canada.

Purpose: Multiple randomized controlled trials have shown that both drug coated balloons (DCBs) and bare metal stents (BMSs) significantly reduce restenosis in femoropopliteal lesions compared with plain balloon angioplasty. However, few studies have directly compared DCB and BMS treatments. Therefore, the goal of our study was to determine if the rate of target lesion revascularization (TLR) differs between DCB and BMS treatment at our center. Read More

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January 2022

[Follow-up of patients after an acute coronary event: the Apulia PONTE-SCA program].

G Ital Cardiol (Rome) 2022 Jan;23(1):63-74

U.O.C. Cardiologia-UTIC, P.O. "San Paolo", Bari, ASL Bari.

Background: Patients who suffered from acute coronary syndrome (ACS) need a tight follow-up in order to optimize therapy and prevent adverse events. The aim of the PONTE-SCA Puglia program was to evaluate the impact of an integrated management of patients between hospital and local territorial outpatient facilities on adherence and outcome of patients discharged after ACS event.

Methods: This was a prospective, longitudinal, cohort study which enrolled patients who suffered ACS and/or coronary revascularization in a Hub hospital of ASL Bari. Read More

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January 2022

Carotid Interventions for Women: The Hazards and Benefits.

Stroke 2022 Jan 5:STROKEAHA121035386. Epub 2022 Jan 5.

Division of Vascular and Endovascular Surgery, University of California San Francisco (P.A.S.).

The goal of the current review is to examine the hazards and benefits of carotid interventions in women and to provide recommendations for the indications for carotid intervention in female patients. Stroke and cerebrovascular disease are prevalent in women. There are inherent biological and other differences in men and women, which affect the manifestations and outcome of stroke, with women experiencing worse disability and higher mortality following ischemic stroke than men. Read More

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January 2022

Idiopathic intracranial hypertension: Pathophysiology, diagnosis and management.

J Clin Neurosci 2022 Jan 17;95:172-179. Epub 2021 Dec 17.

Department of Ophthalmology, New Zealand National Eye Centre, University of Auckland, Auckland, New Zealand. Electronic address:

Idiopathic intracranial hypertension (IIH) is characterized by increased intracranial pressure, manifested by papilledema and radiological findings, in the absence of an identifiable casual factor. The primary symptoms include headache, vision loss, and pulsatile tinnitus, and are recognized to have profound impacts on quality of life and visual function. IIH demonstrates a strong predilection towards obese women of reproductive age, and the population incidence is rising with the growing prevalence of obesity worldwide. Read More

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January 2022

Endovascular repair of acute type B thoracic aortic dissection.

Ann Cardiothorac Surg 2021 Nov;10(6):793-800

Division of Cardiothoracic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas, USA.

Approximately one-third of patients with acute Stanford type B or DeBakey type III aortic dissection (TBAD) will develop complications, including persistent symptoms, malperfusion, enlarging aneurysms and impending rupture. In these cases, TBAD becomes a surgical emergency that requires endovascular intervention to complement the medical therapy. The immediate goal of endovascular therapy is to reestablish flow to the true lumen, stabilize the aneurysm and prevent rupture. Read More

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November 2021

Rehearsals using patient-specific 3D-printed aneurysm models for simulation of endovascular embolization of complex intracranial aneurysms: 3D SIM study.

J Neuroradiol 2021 Dec 13. Epub 2021 Dec 13.

Service de Radiologie, Centre Hospitalier Universitaire de Rennes, France. Electronic address:

Background: In neurovascular treatment planning, endovascular devices to manage complex intracranial aneurysms requiring intervention are often selected based on conventional measurements and interventional neuroradiologist experience. A recently developed technology allows a patient-specific 3D-printed model to mimic the navigation experience. The goal of this study was to assess the effect of pre-procedure 3D simulation on procedural and clinical outcomes for wide-neck aneurysm embolization. Read More

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December 2021

A retrievable, dual-chamber stent protects against warm ischemia of donor organs in a model of donation after circulatory death.

Surgery 2021 Nov 25. Epub 2021 Nov 25.

Division of Vascular Surgery, University of Pittsburgh Medical Center, PA; McGowan Institute for Regenerative Medicine, University of Pittsburgh, PA; Department of Surgery, University of Pittsburgh Medical Center, PA; Division of Vascular Surgery, Ohio State University Wexner Medical Center, Columbus, OH. Electronic address:

Background: Ischemic injury during the agonal period of donation after circulatory death donors remains a significant barrier to increasing abdominal transplants. A major obstacle has been the inability to improve visceral perfusion, while at the same time respecting the ethics of the organ donor. A retrievable dual-chamber stentgraft could potentially isolate the organ perfusion from systemic hypotension and hypoxia, without increasing cardiac work or committing the donor. Read More

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November 2021

New Method for Preparing Small-Caliber Artificial Blood Vessel with Controllable Microstructure on the Inner Wall Based on Additive Material Composite Molding.

Micromachines (Basel) 2021 Oct 26;12(11). Epub 2021 Oct 26.

School of Mechatronics Engineering and Automation, Shanghai University, Shanghai 200444, China.

The diameter of most blood vessels in cardiovascular and peripheral vascular system is less than 6 mm. Because the inner diameter of such vessels is small, a built-in stent often leads to thrombosis and other problems. It is an important goal to replace it directly with artificial vessels. Read More

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October 2021

Feasibility and Clinical Outcomes of 48 mm Drug-Eluting Stents in the Management of Patients With Coronary Artery Disease.

J Invasive Cardiol 2021 Dec 24;33(12):E960-E967. Epub 2021 Nov 24.

Faculty of Medicine, Cardiology Department, Champlion Street, El Azarita, Alexandria, Egypt.

Background: Long coronary lesions represent a formidable challenge during percutaneous coronary intervention (PCI). Implantation of multiple contiguous stents may result in sections of overlapping stents or gaps of unstented segments and is an independent predictor of restenosis and major adverse cardiovascular events (MACEs).

Objectives: The study goal was to assess the feasibility and short-term clinical outcomes of implanting 48 mm drug-eluting stents (DESs) for the treatment of long lesions in patients with coronary artery disease (CAD). Read More

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December 2021

Robotic-assisted laparoscopic cervicouterine anastomosis in a patient with agenesis of the uterine isthmus.

Fertil Steril 2021 Nov 19. Epub 2021 Nov 19.

Department of General Surgery and Medical Surgical Specialties, Gynecological Clinic, University of Catania, Catania, Italy.

Objective: To demonstrate the surgical management of agenesis of the uterine isthmus.

Design: Stepwise description of robotic-assisted laparoscopic cervicouterine anastomosis.

Setting: Academic medical center. Read More

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November 2021

Medical and Endovascular Treatments for Intracranial Atherosclerotic Stenosis: A Network Meta-Analysis.

Transl Stroke Res 2021 Nov 18. Epub 2021 Nov 18.

Interventional Neuroradiology Center, Beijing Tiantan Hospital, Capital Medical University, 119 South 4th Ring West Road, Fengtai District, Beijing, 100070, China.

Medical treatment and endovascular therapy are widely used for intracranial atherosclerotic stenosis, but the best treatment strategy remains uncertain. The goal of this study was to compare the safety and effectiveness of medical treatment, stenting, and primary balloon angioplasty (PBA). We searched PubMed, MEDLINE, and EMBASE for trials comparing these three treatments for intracranial stenosis up to December 24, 2020. Read More

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November 2021

Stent deformation in a sutureless aortic valve bioprosthesis: a pilot observational analysis using imaging and three-dimensional modelling.

Eur J Cardiothorac Surg 2021 Nov 13. Epub 2021 Nov 13.

Department of Cardiovascular Engineering, Institute of Applied Medical Engineering, Helmholtz Institute, Medical Faculty, RWTH Aachen University, Aachen, Germany.

Objectives: The goal of this analysis of the Perceval aortic bioprosthesis was to investigate the ovalization/deformation of the Perceval prosthesis stent after implantation and its propensity for cusp dysfunction, fluttering, fibrosis and blockage.

Methods: Between August 2014 and May 2019, a total of 134 patients (52% female) underwent aortic valve replacement with the Perceval bioprosthesis. We reconstructed three-dimensional models of the Perceval stent using thorax computed tomography scans for 16 patients employing the software Mimics (Materialise NV, Leuven, Belgium) and analysed the ovality of the stents. Read More

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November 2021

Isolated Ruptured Paravisceral Penetrating Aortic Ulcers.

Ann Vasc Surg 2021 Nov 12. Epub 2021 Nov 12.

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of vascular surgery, Berlin, Germany.

Background: The goal of this study is to investigate the clinical presentation, treatment options, and outcomes of the patients with isolated ruptured paravisceral penetrating aortic ulcers (PV-PAU).

Methods: All patients presenting with acute aortic syndrome from 2015 to 2020 were screened, of which patients with isolated ruptured PV-PAU were included in this retrospective study. Study endpoints were the assessment of treatment options, technical success, and clinical outcome. Read More

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November 2021

"Virtual stent" - clinical evaluation and user experience of on-the-fly stent simulation in treatment of cerebral aneurysms.

Interv Neuroradiol 2021 Oct 29:15910199211053131. Epub 2021 Oct 29.

Department of Neuroradiology, 9171University of Erlangen-Nuremberg, Erlangen, Germany.

Background: Predicting final stent position can be challenging when treating cerebral aneurysms. Third-Party software proved helpful in selecting proper stents in treatment planning. Recent angiographic systems provide basic stent simulation capabilities integrated in the post-processing software to simulate stent position. Read More

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October 2021

The Role of Lumen-Apposing Metal Stents in Transmural Endoscopic Drainage of Postinflammatory Pancreatic and Peripancreatic Fluid Collections.

Gastroenterol Res Pract 2021 13;2021:4351151. Epub 2021 Oct 13.

Department of General, Gastroenterological and Oncological Surgery, Collegium Medicum, Nicolaus Copernicus University, Torun, Poland.

Rapid development of advanced gastrointestinal endoscopic techniques contributed to the appearance of new biomedical materials including polymers, which are used for the production of different types of endoprostheses. Endotherapy (ET) of postinflammatory pancreatic and peripancreatic fluid collections (PPFCs) with the use of lumen-apposing metal stent (LAMS) is an effective method of treatment. This paper describes the high efficacy of ET and its potential complications, which are mostly related to the design of the LAMS used. Read More

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October 2021

[stent thrombosis : A won battle ? (data from the France PCI registry)].

Ann Cardiol Angeiol (Paris) 2021 Dec 20;70(6):388-394. Epub 2021 Oct 20.

Service de cardiologie, Centre Hospitalo-Universitaire Gabriel-Montpied, 63000 Clermont Ferrand, France.

Goal: The aim of the study is to assess the incidence, risk factors and prognosis of definite stent thrombosis (ST) at 1 year in the France PCI multicenter prospective registry.

Patients And Methods: Only patients who underwent coronary angioplasty with at least one stent implantation between 1 January 2014 and 31 December 2019 were included. The population was separated into 2 groups: the "ST" group with stent thrombosis and the "control" group without stent thrombosis. Read More

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December 2021

Targeting smooth muscle cell phenotypic switching in vascular disease.

JVS Vasc Sci 2021 15;2:79-94. Epub 2021 May 15.

Department of Medicine, Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, Conn.

Objective: The phenotypic plasticity of vascular smooth muscle cells (VSMCs) is central to vessel growth and remodeling, but also contributes to cardiovascular pathologies. New technologies including fate mapping, single cell transcriptomics, and genetic and pharmacologic inhibitors have provided fundamental new insights into the biology of VSMC. The goal of this review is to summarize the mechanisms underlying VSMC phenotypic modulation and how these might be targeted for therapeutic benefit. Read More

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Secondary Interventions After TEVAR for Aortic Dissection.

Tech Vasc Interv Radiol 2021 Jun 26;24(2):100753. Epub 2021 Jul 26.

Division of Vascular and Interventional Radiology, Department of Radiology and Medical Imaging, University of Virginia Health System, Charlottesville, VA. Electronic address:

The goal of thoracic endograft placement in type B aortic dissection is to prevent aneurysmal degeneration and other complications. Although TEVAR is a highly effective tool for managing type B aortic dissection, many patients will require additional interventions. In this article, we present a case-based review of techniques for the management of persistent false lumen perfusion and stent-graft induced new entry tears after TEVAR for aortic dissection. Read More

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May-Thurner syndrome with inferior mesenteric vein drainage and porta system - Case report.

Radiol Case Rep 2021 Nov 13;16(11):3534-3539. Epub 2021 Sep 13.

Interventional Radiologist, Department of Radiology, General Hospital of Mexico - National Autonomous University of Mexico, CP, 06727, USA.

We present the case of a 12-year-old girl with a history of vascular anomalies in the lower pelvic limbs and back, who developed unilateral deep vein thrombosis of the left lower limb after her pubertal development, she was diagnosed with May-Thurner syndrome with an abnormal venous drainage of the pelvic structures through the superior hemorrhoidal veins to the inferior mesenteric vein towards the porta system, this being a chronic manifestation. This kind of behavior has not been documented in the reviewed medical literature. Secondarily, balloon angioplasty was performed without breaking the stenotic ring. Read More

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November 2021

Ischemic Nephropaty: The Role of the Renal Artery Stenosis Revascularization on Renal Stem Cells.

Medicina (Kaunas) 2021 Sep 8;57(9). Epub 2021 Sep 8.

Nephrologic Unit, Department of Translational and Precision Medicine, University of Rome 'La Sapienza', 00185 Rome, Italy.

We report the case of a 65-year-old man with acute GFR decline to 37 mL/min and uncontrolled high blood pressure. He was suspected for renovascular hypertension and underwent a renal color Doppler ultrasound scan that detected a bilateral atherosclerotic renal artery stenosis. A digital selective angiography by percutaneous transluminal angioplasty and stenting (PTRAs) was successfully performed. Read More

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September 2021

Progress on developing an effective below-the-knee drug-coated balloon.

Rev Cardiovasc Med 2021 Sep;22(3):585-595

Division of Vascular and Endovascular Surgery, University of California, San Francisco, CA 94143, USA.

Infrapopliteal atherosclerotic disease continues to present the greatest conundrum for effective endovascular therapies. To date, conventional angioplasty has been fraught with early restenosis and recoil in these complex, long, calcified, and occlusive lesions. The success of metallic drug-eluting stents in coronary arteries has not carried over to below-the-knee arteries. Read More

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September 2021

Three-Year Results from the Venovo Venous Stent Study for the Treatment of Iliac and Femoral Vein Obstruction.

Cardiovasc Intervent Radiol 2021 Dec 20;44(12):1918-1929. Epub 2021 Sep 20.

Becton Dickinson Peripheral Interventions, Tempe, AZ, USA.

Purpose: To assess safety and patency of the Venovo venous stent for the treatment of iliofemoral vein obstruction.

Materials And Methods: Twenty-two international centers enrolled 170 patients in the VERNACULAR study (93 post-thrombotic syndrome; 77 non-thrombotic iliac vein lesions). Primary outcome measures were major adverse events at 30 days and 12-month primary patency (freedom from target vessel revascularization, thrombotic occlusion, or stenosis > 50%). Read More

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December 2021

Multifunctional Meta-Tribomaterial Nanogenerators for Energy Harvesting and Active Sensing.

Nano Energy 2021 Aug 16;86. Epub 2021 Apr 16.

Department of Civil and Environmental Engineering, University of Pittsburgh, Pittsburgh, PA, USA.

Discovering novel multifunctional metamaterials with energy harvesting and sensing functionalities is likely to be the next technological evolution of the metamaterial science. Here, we introduce a novel concept called self-aware composite mechanical metamaterial (SCMM) that can transform mechanical metamaterials into nanogenerators and active sensing mediums. In pursuit of this goal, we examine new paradigms where finely tailored and seamlessly integrated self-recovering snapping microstructures composed of topologically different triboelectric materials can form self-powering and self-sensing meta-tribomaterial systems. Read More

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3- or 1-Month DAPT in Patients at High Bleeding Risk Undergoing Everolimus-Eluting Stent Implantation.

JACC Cardiovasc Interv 2021 09;14(17):1870-1883

Cardiocentro Ticino, Lugano and Bern University Hospital, Bern, Switzerland.

Objectives: The aim of this study was to evaluate 2 abbreviated dual-antiplatelet therapy (DAPT) regimens in patients at high bleeding risk (HBR) undergoing percutaneous coronary intervention (PCI).

Background: Current-generation drug-eluting stents are preferred over bare-metal stents for HBR patients, but their optimal DAPT management remains unknown.

Methods: The XIENCE Short DAPT program included 3 prospective, multicenter, single-arm studies enrolling HBR patients who underwent successful PCI with a cobalt-chromium everolimus-eluting stent. Read More

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September 2021

Vascular graft infection in the aortoiliac territory - our view in the light of European Society for Vascular Surgery Guidelines the retrospective observation study.

Rozhl Chir 2021 ;100(7):330-338

Introduction: Vascular graft infection in the aortoiliac territory (abdominal VGI) is undoubtedly one of the most serious complications in vascular surgery. The treatment is burdened with high mortality and morbidity rates. In 2020, the Guidelines on the Management of Vascular Graft and Endograft Infections were published by the European Society for Vascular Surgery (ESVS). Read More

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September 2021

Changes of stent-graft orientation after frozen elephant trunk treatment in aortic dissection.

Eur J Cardiothorac Surg 2021 Dec;61(1):142-149

Department of Thoracic and Cardiovascular Surgery, West-German Heart and Vascular Center Essen, Essen, Germany.

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Objectives: Our goal was to evaluate the extent of stent-graft (SG) elastic recoil in the descending aorta after the frozen elephant trunk procedure in acute (AAD) and chronic (CAD) aortic dissection as well as the impact of SG movement on distal stent graft-induced new entry (d-SINE).

Methods: We retrospectively analysed 149 (105 AAD, 44 CAD) of 259 aortic dissection patients after the frozen elephant trunk procedure between January 2005 and April 2019. Inclusion criteria were at least 1-year computed tomography angiography (CTA) aortic examinations during a follow-up time of 3. Read More

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December 2021

Safety and efficacy results of the Flow Redirection Endoluminal Device (FRED) stent system in the treatment of intracranial aneurysms: US pivotal trial.

J Neurointerv Surg 2021 Jul 19. Epub 2021 Jul 19.

Department of Radiology and Biomedical Imaging, UCSF, San Francisco, CA, USA.

Objective: To evaluate the safety and effectiveness of the Flow Redirection Endoluminal Device (FRED) flow diverter in support of an application for Food and Drug Administration approval in the USA.

Methods: 145 patients were enrolled in a prospective, single-arm multicenter trial. Patients with aneurysms of unfavorable morphology for traditional endovascular therapies (large, wide-necked, fusiform, etc) were included. Read More

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A multi-dimensional non-uniform corrosion model for bioabsorbable metallic vascular stents.

Acta Biomater 2021 09 13;131:572-580. Epub 2021 Jul 13.

Key Laboratory for Precision & Non-traditional Machining Technology of Ministry of Education, Dalian University of Technology, No.2 Linggong Road, Dalian, Liaoning 116024, China. Electronic address:

Bioabsorbable metallic vascular stents (BMVSs) are an innovative technological advancement in the medical engineering field of vascular implants. BMVSs have great potential to revolutionize vascular intervention, but the lack of understanding of the construction material's natural corrosion within the body inhibits the use in clinical medicine. In this study, a corrosion function concept for in vivo implants was created to develop a multi-dimensional, non-uniform corrosion model with a larger goal of simulating the mechanical integrity of BMVSs. Read More

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September 2021

Successful percutaneous treatment of occlusive spontaneous coronary artery dissection with a 'pull-back injection technique': case report.

Eur Heart J Case Rep 2021 Jun 30;5(6):ytab165. Epub 2021 Jun 30.

Clinical Cardiology Unit, Hospital Universitario HM Sanchianarro, HM Hospitales. C/Oña 10, 28050 Madrid, Spain.

Background: Spontaneous coronary artery dissection (SCAD) is a rare condition that can cause acute coronary syndrome, typically in young patients without classical cardiovascular risk factors. Although in SCAD the conservative management is preferable, in cases with complete occlusion of the artery an invasive treatment may be required. In such cases, the goal of the percutaneous intervention should be to restore the connection between the true and false lumen recovering the distal flow of the vessel. Read More

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