76 results match your criteria giant bcc

Crystal Structure of Symmetric Ice X in HO-H and HO-He under Pressure.

J Phys Chem Lett 2021 May 12;12(19):4707-4712. Epub 2021 May 12.

Institute of Shock Physics and Department of Chemistry, Washington State University, Pullman, Washington 99164, United States.

Ice VII and ice X are the two most dominant phases, stable over a large pressure range between 2 and 150 GPa and made of fundamentally different chemical bonding. Yet, the two ice phases share a similar bcc-based crystal structure and lattice constants, resulting in a challenge to discern the crystal structure of ice VII and ice X. Here, we present well-resolved X-ray diffraction data of HO in quasi-hydrostatic H and He pressure media, clearly resolving the two ice phases to 130 GPa and the dissociative nature of ice VII to X transition occurring at 20-50 GPa in HO-H and 60-70 GPa in HO-He. Read More

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A lobulated mass on the upper back with prominent vasculature: A giant basal cell carcinoma.

Dermatol Reports 2021 Mar 7;13(1):9046. Epub 2021 Apr 7.

Department of Dermatology, UT Southwestern Medical Center, Dallas, TX.

Basal cell carcinoma (BCC) is characterized by slow but locally invasive growth. Although there is low metastatic potential, if not treated early, these skin cancers can lead to significant morbidity and mortality. In this case report, we present a man with a neglected BCC that developed into what is termed a giant BCC or one that is greater than 5 cm. Read More

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Aggressive progression of a facial super giant basal cell carcinoma.

BMJ Case Rep 2021 Apr 15;14(4). Epub 2021 Apr 15.

Internal Medicine, Jackson Memorial Hospital, Miami, Florida, USA

Super giant basal cell carcinoma (BCC) is a rare oncological entity. A 52-year-old man with a history of a left upper facial lesion for 11 years was transferred to our facility seeking an evaluation. He frequented multiple hospitals where he was treated with antibiotics for this condition. Read More

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Combination of squamous cell carcinoma and basal cell carcinoma arising from a giant verruca vulgaris involving the eyelid.

Am J Ophthalmol Case Rep 2021 Mar 5;21:100858. Epub 2020 Aug 5.

Department of Ophthalmology, Tung Wah Eastern Hospital, Hong Kong.

Purpose: Verruca Vulgaris is a common benign cutaneous lesion which only reported occasionally to have malignant potential. Our purpose is to report a rare case of verruca vulgaris involving the eyelid and subsequently transformed into the combination of squamous cell carcinoma and basal cell carcinoma.

Observations: We reported a case of a 97-year-old female with a chronic biopsy proven verruca vulgaris involving the left lateral canthus. Read More

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Don't Judge a Tumor by Its Biopsy!

Case Rep Dermatol 2020 Sep-Dec;12(3):266-274. Epub 2020 Dec 2.

Department of Plastic Surgery and Breast Surgery, Zealand University Hospital, Roskilde, Denmark.

Trichoblastomas (TBs) are extremely rare, benign hair germ tumors that can mimic basal cell carcinoma (BCC). They usually arise on the head or neck and have a potential for malignant transformation, albeit it is rare. We report a case of giant TB on the forehead of a 75-year-old otherwise healthy woman. Read More

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December 2020

Symptomatic iron deficiency anemia from neglected giant basal cell carcinoma.

JAAD Case Rep 2020 Oct 1;6(10):1019-1023. Epub 2020 Aug 1.

Department of Dermatology, University of Iowa Hospitals and Clinics and VA Medical Center, Iowa City, Iowa.

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October 2020


Acta Chir Plast 2020 ;61(1-4):24-27

Basal cell carcinoma (BCC) is the most prevalent malignancy, with rising incidence worldwide. Despite its naturally slow growth and initially low metastatic potential, it can cause significant morbidity and mortality when unrecognized, inadequately treated or poorly followed up. Authors present the case of a 61-year-old male with a 7-year history of multiple incomplete excisions of a “simple” BCC on the forehead. Read More

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November 2020

Giant Ulcerative Basal Cell Carcinoma with Local Metastasis: A Case Report and Assessment of Surgical Techniques.

Cureus 2019 Dec 20;11(12):e6426. Epub 2019 Dec 20.

Surgery, Brandon Regional Hospital, Brandon, USA.

Giant basal cell carcinoma (GBCC) is a rare skin cancer characterized by an aggressive biological behavior with extensive local invasion, frequent metastasis, and associated poor prognosis. Wide local excision with sentinel lymph node biopsy is often warranted for this condition, and reconstruction by local rotational flap is one of the best surgical techniques for repairing similar skin cancers with a relatively large skin defect. A 59-year-old man who was a former construction worker with a significant smoking history presented with a single giant suspicious chronic ulcerating skin lesion measuring 9 x 7 cm that proved to be a basal cell carcinoma (BCC) on his left shoulder. Read More

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December 2019

Desmoplastic Trichoepithelioma: An Uncommon but Diagnostically Problematic Benign Adnexal Tumor.

Acta Dermatovenerol Croat 2019 Dec;27(4):282-284

Vladimír Bartoš, MD, PhD, MPH, Deapartment of Pathology Faculty Hospital in Žilina, Vojtecha Spanyola 43, 012 07 Žilina, Slovakia;

Dear Editor, I read an interesting recent article by Karimzadeh et al. (1) in an earlier issue of your journal, who provided a comprehensive review addressing a relatively rare benign tumor originating from the hair follicles - trichoepithelioma (TE). They rightly claimed that trichoepithelioma can be divided into the following 3 subgroups: a) multiple familiar TE, b) solitary non-hereditary TE, and c) desmoplastic trichoepithelioma (DTE). Read More

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December 2019

When basal cell carcinomas became giant: an Italian multicenter study.

Int J Dermatol 2020 Mar 27;59(3):377-382. Epub 2019 Nov 27.

Department of Medicine and Aging Science and Dermatologic Clinic, University "G. d'Annunzio", Chieti-Pescara, Chieti, Italy.

Background: Giant basal cell carcinoma (GBCC) is a basal cell carcinoma (BCC) enlarged in a diameter more than 5 cm. Since GBCCs are a highly infrequent entity and the occurrence rate is approximately 0.5-1% out of all BCC types, only anecdotal cases are reported, and causes and characteristics inducing development of this tumor are not defined. Read More

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Giant basal cell carcinoma associated with vitiligo.

Clin Case Rep 2019 Sep 14;7(9):1782-1786. Epub 2019 Aug 14.

Sector of Dermatology and Post Graduation Course in Dermatology - University Hospital and School of Medicine Federal University of Rio de Janeiro Rio de Janeiro Brazil.

We report a woman with two giant Basal cell carcinomas (BCCs) on the back, the largest with 12 cm in diameter, inside a vitiligo plaque. They were metatypical subtype BCC associated with a nodular subtype area. Thinking of BCC in vitiligo lesion is extremely important. Read More

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September 2019

Reappraisal of giant basal cell carcinoma: Clinical features and outcomes.

J Plast Reconstr Aesthet Surg 2020 Jan 28;73(1):53-57. Epub 2019 Jun 28.

Molecular Oncology Group, CRUK Manchester Institute, University of Manchester, Manchester, UK; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia; Division of Musculoskeletal and Dermatological Sciences, University of Manchester, Manchester Academic Health Science Centre, Manchester.

Background: Giant basal cell carcinoma (GBCC) is a rare subgroup of basal cell carcinomas with a diameter of >5 cm. Current evidence about determining factors is conflicting, suggesting patient neglect, on the one hand, and biologically aggressive behaviour, on the other, with outcomes varying from clearance to death. We aimed to clarify the natural history of GBCC and its response to treatment. Read More

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January 2020

Giant basal cell carcinoma of the nasal pyramid - case report.

Rom J Morphol Embryol 2019 ;60(1):255-259

Department of Otorhinolaryngology, Emergency County Hospital of Constanţa, Romania; Department of Psychology, Faculty of Dental Medicine, "Ovidius" University of Constanţa, Romania;

Basal cell carcinoma (BCC) is a frequent form of skin cancer, which usually affects people that have been exposed to the sunlight for longer periods of time. The cells of the lower part of the epidermis are called the basal cell layer. These cells constantly divide to form new cells to replace the squamous cells that wear off the skin's surface. Read More

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December 2019

Giant basal cell carcinoma: clinical-histological characteristics of 115 cases.

Int J Dermatol 2019 Dec 10;58(12):1430-1434. Epub 2019 Apr 10.

Medical Research Division, UMAE Hospital de Pediatria CMNO, IMSS, Guadalajara, Jalisco, Mexico.

Introduction: Giant basal cell carcinoma (GBCC) is a tumor ≥5 cm in size, with aggressive biological behavior, that represents 1% of basal cell carcinomas (BCC), and studies regarding it are scarce. Our objective was to investigate the clinical-histopathological characteristics of GBCC and the risk factors associated with its development.

Methods: A retrospective study over 8 years included patients with the clinical and histopathological diagnosis of GBCC. Read More

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December 2019

Les difficultés du diagnostic : du carcinome basocellulaire aux tumeurs trichoblastiques: From basal cell carcinoma to trichoblastic tumors: a diagnostic challenge.

B Cribier

Ann Dermatol Venereol 2018 Nov;145 Suppl 5:VS3-VS11

Clinique dermatologique, hôpitaux universitaires de Strasbourg, 1, place de l'Hôpital, 67091 Strasbourg cedex, France. Electronic address:

Basal cell carcinoma (BCC) is a very common tumor, of which the diagnosis is generally easy. Clinical prediction of histopathological subtype however is however often difficult, i.e. Read More

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November 2018

Transposition cutaneous flap and split skin mesh graft as combined optimal treatment approach for giant neglected multicentric BCC of the shoulder.

J Eur Acad Dermatol Venereol 2019 Jan 22;33(1):e12-e13. Epub 2018 Jun 22.

Department of General, Vascular and Abdominal Surgery, Medical Institute of Ministry of Interior, General Skobelev 79, 1606, Sofia, Bulgaria.

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January 2019

Conventional Versus Giant Basal Cell Carcinoma, a Review of 57 Cases: Histologic Differences Contributing to Excessive Growth.

Indian J Dermatol 2018 Mar-Apr;63(2):147-154

Department of Dermatology, University of Alabama, Birmingham, AL, USA.

Background: Giant basal cell carcinoma (GBCC) is defined as a basal cell carcinoma (BCC) exceeding 5 cm in size. While these tumors impart significant morbidity due to local tissue destruction and have a higher rate of metastatic disease than their conventional (smaller) counterparts, reasons for their large size remain unclear. While theories relating to neglect or faster growth rate are often invoked; to date, there has not been a comprehensive evaluation of the histologic features of these large tumors that may contribute to their size. Read More

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Description of patients excluded for Mohs surgery after pre-surgical evaluation: data from the Regesmohs Spanish registry.

Actas Dermosifiliogr (Engl Ed) 2018 May 17;109(4):346-350. Epub 2018 Jan 17.

Clínica Universidad de Navarra, Pamplona, España.

Background: Regesmohs registry is a nationwide registry including patients evaluated for Mohs surgery in 17 Spanish centres since July 2013. Given that Mohs surgery is the therapy with best results for high risk basal cell carcinoma (BCC) and other skin tumours, we wanted to describe the reasons that lead to some patients being excluded from this therapy and the alternative treatments that they received. These data may be useful to avoid excluding patients for Mohs surgery use, to estimate the healthcare demand of these patients and the demand for Hedgehog inhibitors therapy in this group. Read More

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A Rare Case of Giant Basal Cell Carcinoma of the Abdominal Wall: Excision and Immediate Reconstruction with a Pedicled Deep Inferior Epigastric Artery Perforator (DIEP) Flap.

Am J Case Rep 2017 Dec 4;18:1284-1288. Epub 2017 Dec 4.

Department of Surgical, Oncological and Dental Disciplinary, Plastic Surgery Section, University of Palermo, Palermo, Italy.

BACKGROUND Basal cell carcinoma (BCC) greater than 5 cm in diameter is called giant basal cell carcinoma (GBCC), or super giant basal cell carcinoma if it has a diameter larger than 20 cm. Giant BCC only accounts for 0.5% of BCCs and super giant BCC is exceedingly rare. Read More

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December 2017

Basal Cell Carcinoma in a Childhood Cancer Survivor: What Neurosurgeons Should Avoid.

Skin Appendage Disord 2017 Oct 24;3(4):202-204. Epub 2017 May 24.

First Department of Dermatology, Aristotle University of of Thessaloniki, Thessaloniki, Greece.

Among childhood cancer survivors (CCSs), non-melanoma skin cancer (NMSC) is the most common type of second malignancy. Morbidity related to the development of NMSC in this group of patients may be sometimes unpredictable and difficult to manage. We present the case of a 49-year-old female who was a CCS and developed giant superficial basal cell carcinomas (sBCCs) over the previously irradiated field of the scalp. Read More

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October 2017

Basal cell carcinoma of the scalp with destruction and invasion into the calvarium and dura mater: Report of 7 cases and review of literature.

J Clin Neurosci 2018 Jan 23;47:190-197. Epub 2017 Oct 23.

Department of Neurosurgery, Vilnius Univeristy Hospital, Vilnius, Lithuania.

Basal cell carcinoma (BCC) is the most common skin malignancy in humans. Giant BCC is a rarer entity that is characterised by aggressive biological behaviour. Intracranial invasion by a BCC on the scalp is extremely rare. Read More

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January 2018

Introgression of Black Rot Resistance from to Cauliflower ( Group) through Embryo Rescue.

Front Plant Sci 2017 18;8:1255. Epub 2017 Jul 18.

National Agri-Food Biotechnology InstituteMohali, India.

Black rot caused by pv. () is a very important disease of cauliflower ( group) resulting into 10-50% yield losses every year. Since there is a dearth of availability of resistance to black rot disease in (C genome), therefore exploration of A and B genomes was inevitable as they have been reported to be potential reservoirs of gene(s) for resistance to black rot. Read More

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Delayed Diagnosis of Basal Cell Carcinoma of the Upper Lip: The Possible Role of Incidental Multinucleated Foreign Body Giant Cells.

Case Rep Dermatol 2017 May-Aug;9(2):50-54. Epub 2017 Jun 16.

Department of Dermatology, University of Texas Medical Branch, Galveston, Texas, USA.

Herpes simplex and basal cell carcinoma (BCC) can have similar clinical presentations due to overlapping lesional morphology. We describe the unusual case of a BCC masquerading as herpes labialis due to a possible false-positive Tzanck smear. The confounding diagnosis led to a failed trial of valacyclovir and subsequent loss of the patient for 1 year before the lesion was biopsied and diagnosed as a BCC. Read More

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Approach to management of giant basal cell carcinomas.

Cutis 2017 May;99(5):356-362

Division of Dermatology, Creighton University School of Medicine, Omaha, Nebraska, USA.

Basal cell carcinoma (BCC) is a common nonmelanoma skin cancer with increasing incidence in the United States and worldwide. It is strongly linked to UV radiation exposure and typically is slow growing. Malignancy in BCCs is due to local growth and invasion rather than metastasis, and the prognosis is generally favorable. Read More

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A Giant Basal Cell Carcinoma Misdiagnosed and Mistreated as a Chronic Venous Ulcer.

Acta Dermatovenerol Croat 2016 Dec;24(4):296-298

Dijana Celić, MD, PhD. Medikol Outpatient Department. Voćarska 106. 10 000 Zagreb, Croatia;

Basal cell carcinoma (BCC) is the most common cutaneous malignancy. Giant BCCs are quite rare. They can cause extensive local invasion, disfigurement, and metastasis. Read More

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December 2016

Giant Basal Cell Carcinomas Arising on the Bilateral Forearms of a Patient: A Case Report and Review of Nonsurgical Treatment Options.

Case Rep Dermatol 2016 Sep-Dec;8(3):363-368. Epub 2016 Dec 13.

Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.

Giant basal cell carcinomas (GBCCs) are large basal cell carcinomas (BCCs; <5 cm) with a greater propensity to invade and metastasize than standard BCCs. The presence of 2 GBCCs in a single individual is rare. We present the case of a 71-year-old Caucasian male with bilateral GBCCs on the dorsal forearms, measuring 130 cm and 24 cm, respectively, that developed over a 21-year period. Read More

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December 2016

Giant Basal Cell Carcinomas Express Neuroactive Mediators and Show a High Growth Rate: A Case-Control Study and Meta-Analysis of Etiopathogenic and Prognostic Factors.

Am J Dermatopathol 2017 Mar;39(3):189-194

*Albany Medical College, Albany, NY; †Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY; ‡VA Boston Healthcare System Geriatric Research, Education and Clinical Center, Boston, MA; §Department of Dermatology, University of Alabama at Birmingham, VA Medical Center, Birmingham, AL; ¶Western Pathology, Inc., San Luis Obispo, CA; ‖Department of Plastic Surgery, Albany Medical College, Albany, NY; **Loyola Stritch School of Medicine, Maywood, IL; and ††Department of Pathology, Albany Medical College, Albany, NY.

Background: Giant basal cell carcinomas (GBCCs), (BCC ≥ 5 cm), are often painless, destructive tumors resulting from poorly understood patient neglect.

Objectives: To elucidate etiopathogenic factors distinguishing GBCC from basal cell carcinoma (BCC) and identify predictors for disease-specific death (DSD).

Methods: Case-control study examining clinicopathologic and neuroactive factors (β-endorphin, met-enkephalin, serotonin, adrenocorticotropic hormone, and neurofilament expression) in GBCC and BCC. Read More

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Adenoid basal cell carcinoma: a rare facet of basal cell carcinoma.

BMJ Case Rep 2016 Apr 19;2016:10.1136/bcr-2015-214166. Epub 2016 Apr 19.

Department of Oral Pathology and Microbiology, Karnavati School of Dentistry, Gandhinagar, Gujarat, India.

Basal cell carcinoma (BCC) is a common, locally invasive epithelial malignancy of skin and its appendages. Every year, close to 10 million people get diagnosed with BCC worldwide. While the histology of this lesion is mostly predictable, some of the rare histological variants such as cystic, adenoid, morpheaform, infundibulocystic, pigmented and miscellaneous variants (clear-cell, signet ring cell, granular, giant cell, adamantanoid, schwannoid) are even rarer, accounting for <10% of all BCC's. Read More

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A rare case of super giant basal cell carcinoma.

JAAD Case Rep 2015 Sep 29;1(5):280-2. Epub 2015 Jul 29.

Western University, Silver Falls Dermatology, Salem, Oregon.

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September 2015