736 results match your criteria generally valued

Patients' and parents' perspective on the implementation of Patient Reported Outcome Measures in pediatric clinical practice using the KLIK PROM portal.

Qual Life Res 2021 Jul 29. Epub 2021 Jul 29.

Child and Adolescent Psychiatry & Psychosocial Care, Amsterdam Reproduction and Development, Amsterdam Public Health, Amsterdam UMC, University of Amsterdam, Emma Children's Hospital, Meibergdreef 9, Amsterdam, The Netherlands.

Introduction: The KLIK Patient Reported Outcome Measures (PROM) portal ( www.hetklikt.nu ) has been implemented since 2011 in clinical practice in over 20 Dutch hospitals. Read More

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Experiences and perspectives of chiropractic students graduating from an alternate admission track plan.

J Chiropr Educ 2021 Jul 28. Epub 2021 Jul 28.

Objective: This study explored self-reported experiences of alternate admission track plan (AATP) students who completed a chiropractic training program at a US chiropractic college.

Methods: Our institution conducted semistructured exit interviews with 16 graduating AATP students. Our consensus-drafted open-ended interview questions probed in-depth for these students' experience throughout the training program, with national board exams, their personal characteristics, their satisfaction with the training program generally, and with the AATP program specifically. Read More

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Does life history mediate discharge as a driver of multi-decadal changes in populations of freshwater fish?

Ecol Appl 2021 Jul 26:e02430. Epub 2021 Jul 26.

Department of Environment, Land, Water and Planning, Arthur Rylah Institute for Environmental Research, 123 Brown Street, Heidelberg Victoria, 3084, Australia.

Understanding how and why the size of populations varies is critical knowledge for conservation and management. While considerable work has explored how different demographic parameters affect population growth, less is known the drivers of variability in these parameters. Long-term time series tracking population size that are coupled with empirical data to examine the relative importance of different drivers are rare, especially in freshwater systems. Read More

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Environmental Physical and Perceived Quality in Hospice.

HERD 2021 Jul 21:19375867211028160. Epub 2021 Jul 21.

Department of Planning, Design, and Technology of Architecture, Sapienza University of Rome, Italy.

Objectives: This study presents the application of post-occupancy evaluations (POEs) methodologies to facilities for palliative-hospice care, in order to directly assess the physical-spatial qualities better suited for the specific psychological needs of "fragile" users and to ensure better architectural quality in new projects and in renovation measures.

Background: In international literature, there are few studies concerning the application of POEs to hospice, assessing the impact of individual environmental factors on users' psychoemotional reactions. The set of elements that patients and their families perceive as important, defining the architectural quality of a hospice, has not been sufficiently investigated yet. Read More

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The Screening of Combinatorial Peptide Libraries for Targeting Key Molecules or Protein-Protein Interactions in the NF-κB Pathway.

Methods Mol Biol 2021 ;2366:343-356

Centre for Molecular Immunology and Inflammation, Department of Immunology and Inflammation, Imperial College London, London, UK.

Peptides are emerging as an increasingly dependable class of therapeutics in the treatment of cancer and metabolic and cardiovascular diseases, which are all areas of high interest to the pharmaceutical industry. The global market for peptide therapeutics was valued at about 25 billion USD in 2018 and is estimated to reach 57.2 billion USD by the end of 2027. Read More

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January 2021

Public Response on Social Media to a Social Marketing Campaign for Influencing Attitudes towards Boating Safety.

Int J Environ Res Public Health 2021 06 16;18(12). Epub 2021 Jun 16.

BC Injury Research and Prevention Unit, BC Children's Hospital, Vancouver, BC V6H 3V4, Canada.

The purpose of this research paper is to assess the response on Facebook to a social marketing campaign for recreational boating safety. The campaign ran for the 2018 and 2019 boating seasons in British Columbia, Canada. Messages related to boating safety were delivered in multi-media formats, including ten Facebook posts. Read More

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Quantum Uncertainties and Holism Seem to Render Irrelevant Qudit-Semantics.

Roberto Leporini

Entropy (Basel) 2021 Jun 10;23(6). Epub 2021 Jun 10.

Department of Economics, University of Bergamo, Via dei Caniana, 2, I-24127 Bergamo, Italy.

We consider a semantics based on the peculiar holistic features of the quantum formalism. Any formula of the language gives rise to a quantum circuit that transforms the density operator associated to the formula into the density operator associated to the atomic subformulas in a reversible way. The procedure goes from the whole to the parts against the compositionality-principle and gives rise to a semantic characterization for a new form of quantum logic that has been called "Łukasiewicz quantum computational logic". Read More

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Polycystic Ovary Syndrome Models of Care: A Review and Qualitative Evaluation of a Guideline-Recommended Integrated Care.

Semin Reprod Med 2021 Jun 29. Epub 2021 Jun 29.

Monash Centre for Health Research and Implementation, School of Public Health and Preventive Medicine, Monash University, Clayton, Victoria, Australia.

Polycystic ovary syndrome (PCOS) is a heterogeneous disorder and many women are dissatisfied with their healthcare under the current fragmented health services. Here, we review existing literature on PCOS healthcare services and qualitatively evaluate an integrated PCOS service based on experiences of women with PCOS. Limited prior PCOS-dedicated services have been studied and their quantitative and efficacy-focused evaluations are summarized. Read More

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Evaluation of a Multidisciplinary Cachexia and Nutrition Support Service- The Patient and Carers Perspective.

J Patient Exp 2021 16;8:2374373520981476. Epub 2021 Jan 16.

School of Medicine, Deakin University, Waurn Ponds, Victoria, Australia.

The Barwon Health Cachexia & Nutrition Support Service (CNSS) is an outpatient service focused on improving clinical outcomes and quality of life for patients with or at high risk of cancer cachexia. Patients see a multidisciplinary team, comprising a palliative medicine physician, physiotherapist, dietitian, and nurse practitioner. This study evaluated the service from patient and carer perspectives. Read More

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January 2021

Quality of work life of paramedics practicing community paramedicine in northern Ontario, Canada: a mixed-methods sequential explanatory study.

Rural Remote Health 2021 Jun 20;21(2):6558. Epub 2021 Jun 20.

Centre for Rural and Northern Health Research, Laurentian University, Sudbury, Ontario, Canada. Present address: Lakehead University, Thunder Bay, Ontario, Canada

Introduction: This article aimed to evaluate pilot community paramedicine (CP) programs in northern Ontario from the perspectives of paramedics to gain program recommendations related to both rural and urban settings.

Methods: An online questionnaire was created and distributed to 879 paramedics with and without CP experience employed at eight emergency medical services providers in northern Ontario. An explanatory sequential design was used to analyze and synthesize the results from the quantitative survey items and the open-ended responses. Read More

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Comparison of Patient Versus Trained Observer Assessments of Healthcare Providers' Use of Motivational Interviewing Techniques for Patients Experiencing Depression and Anxiety in the Dominican Republic.

J Clin Psychol Med Settings 2021 Jun 18. Epub 2021 Jun 18.

School of Psychology, Universidad Autónoma de Santo Domingo, Santo Domingo, Dominican Republic.

In settings with limited mental health system capacity, integrated care and the improvement of patient-provider communication surrounding common mental disorders is critical to advancing treatment outcomes. We trained primary care providers in the Dominican Republic in motivational interviewing (MI) to improve communication with patients experiencing depression and anxiety. Providers were randomized to an intervention group, which received MI training, or a control group. Read More

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Towards Personalising the Use of Biologics in Rheumatoid Arthritis: A Discrete Choice Experiment.

Patient 2021 Jun 18. Epub 2021 Jun 18.

Manchester Centre for Health Economics, The University of Manchester, Oxford Road, Manchester, M13 9PL, UK.

Introduction: There have been promising developments in technologies and associated algorithm-based prescribing ('stratified approach') to target biologics to sub-groups of people with rheumatoid arthritis (RA). The acceptability of using an algorithm-guided approach in practice is likely to depend on various factors.

Objective: This study quantified preferences for an algorithm-guided approach to prescribing biologics (termed 'biologic calculator'). Read More

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Patient Perspectives and Experiences of Preventive Treatments and Self-Injectable Devices for Migraine: A Focus Group Study.

Patient 2021 Jun 16. Epub 2021 Jun 16.

Eli Lilly, Indianapolis, IN, USA.

Background: Although several self-injectable preventive treatments for migraine have become available, they are not yet widely used. Thus, understanding patients' perceptions towards them is limited.

Objective: This study aimed to inform the design of a preference-elicitation instrument, which is being developed to quantify preventive treatment preferences of people with migraine. Read More

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Process Evaluation of the SImplification of Medications Prescribed to Long-tErm Care Residents (SIMPLER) Cluster Randomized Controlled Trial: A Mixed Methods Study.

Int J Environ Res Public Health 2021 05 27;18(11). Epub 2021 May 27.

Centre for Medicine Use and Safety, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.

Complex medication regimens are highly prevalent, burdensome for residents and staff, and associated with poor health outcomes in residential aged care facilities (RACFs). The SIMPLER study was a non-blinded, matched-pair, cluster randomized controlled trial in eight Australian RACFs that investigated the one-off application of a structured 5-step implicit process to simplify medication regimens. The aim of this study was to explore the processes underpinning study implementation and uptake of the medication simplification intervention. Read More

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Viewing faculty development through an organizational lens: Sharing lessons learned.

Med Teach 2021 May 31:1-6. Epub 2021 May 31.

School of Medicine, University of Calgary, Calgary, Canada.

Introduction: Faculty Development (FD) plays a key role in supporting education, especially during times of change. The effectiveness of FD often depends upon organizational factors, indicating a need for a deeper appreciation of the role of institutional context. How do organizational factors constrain or enhance the capacity of faculty developers to fulfil their mandates?

Methods: Using survey research methodology, data from a survey of FD leaders at Canadian medical schools were analyzed using Bolman and Deal's four frames: Symbolic, Political, Structural, and Human Resource (HR). Read More

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Proton Beam Therapy for Cancer in Children and Adults: A Health Technology Assessment.


Ont Health Technol Assess Ser 2021 6;21(1):1-142. Epub 2021 May 6.

Background: Proton beam therapy has potential to reduce late toxicity in cancer treatment by reducing the risk of damage to surrounding healthy tissues. We conducted a health technology assessment of proton beam therapy, compared with photon therapy, for children and adults with cancer requiring radiotherapy. Our assessment included an evaluation of safety, effectiveness, cost-effectiveness, the budget impact of publicly funding the construction and use of proton beam therapy in Ontario, and patient preferences and values. Read More

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Patient partners' perspectives of meaningful engagement in synthesis reviews: A patient-oriented rapid review.

Health Expect 2021 May 28. Epub 2021 May 28.

Saskatchewan Centre for Patient-Oriented Research, Saskatoon, Saskatchewan, Canada.

Background: A growing literature describes promising practices for patient-oriented research (POR) generally; however, those for systematic reviews are largely derived through the lens of a researcher. This rapid review sought to understand meaningful engagement in synthesis reviews from the patient partner (PP) perspective.

Design: The review team comprised PPs, librarians, SCPOR staff and academic faculty. Read More

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An extended TDM method under probabilistic interval-valued hesitant fuzzy environment for stock selection.

PLoS One 2021 27;16(5):e0252115. Epub 2021 May 27.

Department of Science and Humanities, National University of Computer and Emerging Sciences, Lahore, Pakistan.

Generally, in real decision-making, all the pieces of information are used to find the optimal alternatives. However, in many cases, the decision-makers (DMs) only want "how good/bad a thing can become." One possibility is to classify the alternatives based on minimum (tail) information instead of using all the data to select the optimal options. Read More

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Conducting invasive urodynamics in primary care: qualitative interview study examining experiences of patients and healthcare professionals.

Diagn Progn Res 2021 May 18;5(1):10. Epub 2021 May 18.

Department of Urology, Newcastle upon Tyne NHS Hospital Trust, Newcastle Freeman Hospital, Freeman Road, High Heaton, Newcastle upon Tyne, UK.

Background: Invasive urodynamics is used to investigate the causes of lower urinary tract symptoms; a procedure usually conducted in secondary care by specialist practitioners. No study has yet investigated the feasibility of carrying out this procedure in a non-specialist setting. Therefore, the aim of this study was to explore, using qualitative methodology, the feasibility and acceptability of conducting invasive urodynamic testing in primary care. Read More

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Maximizing Participant Engagement, Participation, and Retention in Cohort Studies Using Digital Methods: Rapid Review to Inform the Next Generation of Very Large Birth Cohorts.

J Med Internet Res 2021 May 14;23(5):e23499. Epub 2021 May 14.

Murdoch Children's Research Institute, Parkville, Australia.

Background: Many current research needs can only be addressed using very large cohorts. In such studies, traditional one-on-one phone, face-to-face, or paper-based engagement may not be feasible. The only realistic mechanism for maintaining engagement and participation at this scale is via digital methods. Read More

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The Gold Coast Integrated Care Programme: The Perspectives of Patients, Carers, General Practitioners and Healthcare Staff.

Int J Integr Care 2021 May 7;21(2):18. Epub 2021 May 7.

Menzies Health Institute Queensland, Griffith University, Queensland, AU.

Introduction: The Australian Gold Coast Integrated Care programme trialled an innovative model of care to proactively manage high risk patients with complex and chronic conditions in collaboration with general practitioners. The objective was to enhance coordination and continuity of care across primary and secondary health services from a single point-of-entry multidisciplinary coordination centre. This case study, embedded in the broader trial, analysed the perceptions of patients, healthcare staff and general practitioners on the adequacy, comprehensiveness, timeliness and acceptability of the new model of care to help inform the decision by the health service whether to adopt it beyond the trial. Read More

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Perceptions of Mobile Health Apps and Features to Support Psychosocial Well-being Among Frontline Health Care Workers Involved in the COVID-19 Pandemic Response: Qualitative Study.

J Med Internet Res 2021 05 31;23(5):e26282. Epub 2021 May 31.

Department of Emergency Medicine, Singapore General Hospital, Singapore, Singapore.

Background: Frontline health care workers are experiencing a myriad of physical and psychosocial challenges amid the COVID-19 pandemic. There is growing recognition that digital technologies have the potential to improve the well-being of frontline workers. However, there has been limited development of wellness interventions using mobile health (mHealth) technology. Read More

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Communication and empathy skills: Essential requisites for patient-centered radiology care.

Eur J Radiol 2021 Jul 3;140:109754. Epub 2021 May 3.

Department of Radiology, Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Groningen, the Netherlands. Electronic address:

Purpose: To investigate how patients value radiologists, using data from the Dutch healthcare assessment website.

Method: The Dutch healthcare assessment website was searched for patient reviews about radiologists in The Netherlands. The scores (scale of 1-10) assigned to the most recent review of each radiologist were extracted. Read More

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To What Extent Can Digitally-Mediated Team Communication in Children's Physical Health and Mental Health Services Bring about Improved Outcomes? A Systematic Review.

Child Psychiatry Hum Dev 2021 May 8. Epub 2021 May 8.

Centre for Applied Autism Research, Department of Psychology, University of Bath, Bath, BA2 7AY, UK.

Digital communication technologies can be used for team consultation, case management, and information sharing in health and mental health services for children and young people (CYP). The objective of the systematic review was to investigate the evidence as to whether digitally-mediated team communication for CYP improves outcomes. We searched PsycINFO, PubMed, Web of Science, and Cochrane Library for relevant studies. Read More

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Accessing Voluntary HIV Testing in the Construction Industry: A Qualitative Analysis of Employee Interviews from the [email protected] Study.

Int J Environ Res Public Health 2021 04 15;18(8). Epub 2021 Apr 15.

School of Health Sciences, University of Nottingham, Nottingham NG7 2HA, UK.

HIV, globally, remains a significant public health issue and community HIV testing can help to identify those with HIV at an early stage of disease. The workplace offers a prime location for provision of opt-in HIV testing as part of wider health promotion initiatives. The construction industry offers a key opportunity for HIV testing provision in a generally male-dominated group exhibiting some risky behaviors related to HIV. Read More

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Ultrasonographic Technique, Appearance, and Diagnostic Accuracy for Common Shoulder Sports Injuries: A Narrative Review.

JBJS Rev 2021 04 22;9(4). Epub 2021 Apr 22.

The Rothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, Pennsylvania.

»: Ultrasonography (US) is valued for its availability, tolerability, low cost, and utility in real-time dynamic evaluation. Its use in diagnosing upper-extremity shoulder injury has expanded, but several features require definition before more widespread adoption can be realized.

»: In particular, the evaluation of rotator cuff tears (RCTs) with US has been extensively studied, and authors generally agree that US is comparable with magnetic resonance imaging for the detection of full-thickness RCTs, whereas partial-thickness RCTs are more difficult to accurately identify with US. Read More

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Extraction of protein from food waste: An overview of current status and opportunities.

Compr Rev Food Sci Food Saf 2021 May 5;20(3):2455-2475. Epub 2021 Apr 5.

Future Food Beacon and Centre of Excellence for Postharvest Biotechnology (CEPB), School of Biosciences, University of Nottingham Malaysia, Jalan broga, Semenyih, Selangor, 43500, Malaysia.

The chief intent of this review is to explain the different extraction techniques and efficiencies for the recovery of protein from food waste (FW) sources. Although FW is not a new concept, increasing concerns about chronic hunger, nutritional deficiency, food security, and sustainability have intensified attention on alternative and sustainable sources of protein for food and feed. Initiatives to extract and utilize protein from FW on a commercial scale have been undertaken, mainly in the developed countries, but they remain largely underutilized and generally suited for low-quality products. Read More

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Parents' experiences of caring for a young child with type 1 diabetes: a systematic review and synthesis of qualitative evidence.

BMC Pediatr 2021 04 4;21(1):160. Epub 2021 Apr 4.

Centre for Population Health Sciences, Usher Institute, University of Edinburgh, Edinburgh, UK.

Aims: To synthesise the qualitative evidence on parents' experiences of caring for a child aged ≤8 years with type 1 diabetes to identify: the challenges they encounter; their views about support received; ways in which support could be improved; and, directions for future research.

Methods: We searched Medline, EMBASE, CINAHL, PsycINFO and Web of Science databases to identify qualitative studies reporting parents' views and experiences of caring for a child with type 1 diabetes aged ≤8 years. Key analytical themes were identified using thematic synthesis. Read More

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Recovery community centers: Characteristics of new attendees and longitudinal investigation of the predictors and effects of participation.

J Subst Abuse Treat 2021 05 13;124:108287. Epub 2021 Jan 13.

Recovery Research Institute, Massachusetts General Hospital and Harvard Medical School, 151 Merrimac Street, Boston, MA 02114, United States of America.

Objective: Recovery community centers (RCCs) have expanded across the U.S., serving as social "recovery hubs" that increase recovery capital (e. Read More

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Non-Hermitian route to higher-order topology in an acoustic crystal.

Nat Commun 2021 Mar 25;12(1):1888. Epub 2021 Mar 25.

Division of Physics and Applied Physics, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore, Singapore.

Topological phases of matter are classified based on their Hermitian Hamiltonians, whose real-valued dispersions together with orthogonal eigenstates form nontrivial topology. In the recently discovered higher-order topological insulators (TIs), the bulk topology can even exhibit hierarchical features, leading to topological corner states, as demonstrated in many photonic and acoustic artificial materials. Naturally, the intrinsic loss in these artificial materials has been omitted in the topology definition, due to its non-Hermitian nature; in practice, the presence of loss is generally considered harmful to the topological corner states. Read More

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