10,189 results match your criteria galli

Correspondence: Author response to Godi et al.

J Physiother 2021 Jun 11. Epub 2021 Jun 11.

Sydney School of Health Sciences, Discipline of Physiotherapy, The University of Sydney, Australia.

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Quantification of the effects of robotic-assisted gait training on upper and lower body strategy during gait in diplegic children with Cerebral Palsy using summary parameters.

Comput Methods Biomech Biomed Engin 2021 Jun 14:1-8. Epub 2021 Jun 14.

IRCCS San Raffaele Roma, Roma, Italy.

The effects of robotic-assisted gait training on upper and lower body strategy during gait in diplegic children with Cerebral Palsy (CP) were quantified using summary parameters (Upper Body Profile Score (UBPS) and Gait Profile Score (GPS)). Firstly, the upper body strategy during gait was assessed in 73 children with CP and 15 healthy children (Control Group: CG): patients with CP exhibited higher values of most of the summary parameters of the upper body position than the CG. Then, the effects of a robotic-assisted gait training in a sub-group of 35 children by means of UBPS were evaluated. Read More

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Excretion of Histomonas meleagridis following experimental co-infection of distinct chicken lines with Heterakis gallinarum and Ascaridia galli.

Parasit Vectors 2021 Jun 13;14(1):323. Epub 2021 Jun 13.

Clinic for Poultry and Fish Medicine, Department for Farm Animals and Veterinary Public Health, University of Veterinary Medicine, Vienna, Austria.

Background: Histomonosis is a severe re-emerging disease of poultry caused by Histomonas meleagridis, a protozoan parasite which survives in the environment via the cecal worm Heterakis gallinarum. Following infection, the parasites reside in the ceca and are excreted via host feces. In the present work, male birds of conventional broiler (Ross 308, R), layer (Lohmann Brown Plus, LB) and a dual-purpose (Lohmann Dual, LD) chicken line were infected with 250 embryonated eggs of Ascaridia galli and Heterakis gallinarum, respectively, with the latter nematode harboring Histomonas meleagridis, to investigate a co-infection of nematodes with the protozoan parasite in different host lines. Read More

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The relative locations of the supraorbital, infraorbital, and mental foramina: A cadaveric study.

J Anat 2021 Jun 12. Epub 2021 Jun 12.

Department of Cell Systems and Anatomy, UT Health San Antonio, San Antonio, Texas, USA.

The purpose of this study is to investigate the applicability of the current surgical guideline stating that the main facial foramina that transmit cutaneous nerves to the face (supraorbital notch/foramen, infraorbital foramen, and mental foramen) are equidistant from the midline in European and Hispanic populations. Previous studies suggest this surgical guideline is not applicable for all ethnicities; however, to our knowledge, no data have been published regarding the accuracy of this guideline pertaining to the Hispanic population. An experimental study was performed on 67 cadavers donated to the Human Anatomy Program at UT Health San Antonio. Read More

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Vaccinations in patients with inflammatory bowel disease.

Dig Liver Dis 2021 Jun 8. Epub 2021 Jun 8.

Department of Biomedical and Clinical Sciences, L Sacco" University of Milan, Via Giovan Battista Grassi 74, Milan 20157, Italy.

Treatment of inflammatory bowel disease (IBD) frequently requires administration of immunosuppressive therapies, which increases susceptibility to a number of infectious pathogens. However, many infections can be prevented by correct and appropriate utilization of vaccinations. While several guidelines have been published on vaccination schedules in patients with IBD, vaccination rates remain suboptimal and even lower than those in the general population. Read More

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Clinical management of patients with thymic epithelial tumors: the recommendations endorsed by the Italian Association of Medical Oncology (AIOM).

ESMO Open 2021 Jun 8;6(4):100188. Epub 2021 Jun 8.

Division of Medical Oncology for Melanoma, Sarcoma, and Rare Tumors, Istituto Europeo di Oncologia, IRCCS, Milan, Italy.

The Italian Association of Medical Oncology recommendations on thymic epithelial tumors, which have been drawn up for the first time in 2020 through an evidence-based approach, report indications on all the main aspects of clinical management of this group of rare diseases, from diagnosis and staging, to new available systemic treatments, such as targeted therapies and immunotherapies. A summary of key recommendations is presented here and complete recommendations are reported as Supplementary Materials, available at https://doi.org/10. Read More

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Epidemiology and clinical features of intestinal protozoan infections detected by Real-time PCR in non-native children within an Italian tertiary care children's hospital: A cross-sectional study.

Travel Med Infect Dis 2021 Jun 9;43:102107. Epub 2021 Jun 9.

Infectious Diseases Unit, Meyer Children's University Hospital, Florence, Italy; Department of Health Sciences, University of Florence, Italy. Electronic address:

Background: Enteric parasite infections are underestimated due to the limited sensitivity and specificity of microscopy, which remains the diagnostic gold standard in routine clinical practice. This could be a major problem in high-income countries, where the burden of parasitic diseases is low. In recent years, Multiplex Real-Time polymerase chain reaction (RT-PCR) based methods have been implemented. Read More

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Editorial: Hormonal Regulation of Non-climacteric Fruit Development and Maturation.

Front Plant Sci 2021 25;12:690691. Epub 2021 May 25.

College of Agronomy and Biotechnology, China Agricultura University, Beijing, China.

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Echocardiographic view and feature selection for the estimation of the response to CRT.

PLoS One 2021 10;16(6):e0252857. Epub 2021 Jun 10.

University of Rennes, CHU Rennes, Inserm, LTSI UMR 1099, Rennes, France.

Cardiac resynchronization therapy (CRT) is an implant-based therapy applied to patients with a specific heart failure (HF) profile. The identification of patients that may benefit from CRT is a challenging task and the application of current guidelines still induce a non-responder rate of about 30%. Several studies have shown that the assessment of left ventricular (LV) mechanics by speckle tracking echocardiography can provide useful information for CRT patient selection. Read More

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[Long-term Quality Control Test of a Ge/Ga Generator].

Kaku Igaku 2021 ;58(1):47-58

Central Institute of Isotope Science, Hokkaido University.

Quality of the Ga solution eluted from a Ge/Ga generator (Galli Eo) was evaluated. Elution was performed 488 times from 21 to 484 days (ca. 15 months) after the calibration date. Read More

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January 2021

Are Epidemiological Estimates Able to Describe the Ability of Health Systems to Cope with COVID-19 Epidemic?

Risk Manag Healthc Policy 2021 31;14:2221-2229. Epub 2021 May 31.

Department of Clinical Sciences and Community Health & DSRC, University of Milan, Milan, Italy.

Introduction: The coronavirus disease 2019 (COVID-19) epidemic is an infectious disease which was declared a pandemic and hit countries worldwide from the beginning of the year 2020. Despite the emergency vigilance plans, health systems in all countries experienced a different ratio of lethality, amount of admissions to intensive care units and quarantine management of positive patients. The aim of this study is to investigate whether some epidemiological estimates could have been useful in understanding the capacity of the Italian Regional Health Services to manage the COVID-19 epidemic. Read More

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MICAL-L1 is required for cargo protein delivery to the cell surface.

Biol Open 2021 Jun 8;10(6). Epub 2021 Jun 8.

Université de Paris, Inserm U1016-CNRS UMR 8104, Institut Cochin, Paris, France.

Secreted proteins are transported along intracellular route from the endoplasmic reticulum through the Golgi before reaching the plasma membrane. Small GTPase Rab and their effectors play a key role in membrane trafficking. Using confocal microscopy, we showed that MICAL-L1 was associated with tubulo-vesicular structures and exhibited a significant colocalization with markers of the Golgi apparatus and recycling endosomes. Read More

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Hepatitis C Virus Protease Inhibitors Show Differential Efficacy and Interactions with Remdesivir for Treatment of SARS-CoV-2 .

Antimicrob Agents Chemother 2021 Jun 7:AAC0268020. Epub 2021 Jun 7.

Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Hvidovre Hospital and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Antivirals targeting SARS-CoV-2 could improve treatment of COVID-19. We evaluated efficacy of clinically relevant hepatitis C virus (HCV) NS3 protease inhibitors (PI) against SARS-CoV-2 and their interactions with remdesivir, the only direct-acting antiviral approved for COVID-19 treatment. HCV PI showed differential potency in short-term treatment assays based on detection of SARS-CoV-2 Spike protein in VeroE6 cells. Read More

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Germinal epimutation of Fragile Histidine Triad (FHIT) gene is associated with progression to acute and chronic adult T-cell leukemia diseases.

Mol Cancer 2021 Jun 6;20(1):86. Epub 2021 Jun 6.

Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS, 66160, USA.

Background: Human T cell Leukemia virus type 1 (HTLV-I) is etiologically linked to adult T cell leukemia/lymphoma (ATL) and an inflammatory neurodegenerative disease called HTLV-I-associated myelopathy or tropical spastic paraparesis (HAM/TSP). The exact genetic or epigenetic events and/or environmental factors that influence the development of ATL, or HAM/TSP diseases are largely unknown. The tumor suppressor gene, Fragile Histidine Triad Diadenosine Triphosphatase (FHIT), is frequently lost in cancer through epigenetic modifications and/or deletion. Read More

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Aquaporins in insulin resistance and diabetes: More than channels!

Redox Biol 2021 Aug 27;44:102027. Epub 2021 May 27.

Department of Medical Biology, Medical University of Bialystok, 15-089, Bialystok, Poland. Electronic address:

Aquaporins (AQPs) are part of the family of the integral membrane proteins. Their function is dedicated to the transport of water, glycerol, ammonia, urea, HO, and other small molecules across the biological membranes. Although for many years they were scarcely considered, AQPs have a relevant role in the development of many diseases. Read More

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An image quality review programme in a population-based mammography screening service.

J Med Radiat Sci 2021 Jun 3. Epub 2021 Jun 3.

Romagna Cancer Registry, Romagna Cancer Institute (Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori", IRST, IRCCS), Meldola, Forlì, Italy.

Introduction: Mammography is one of the most technically demanding radiographic processes, and mammography quality assurance initiatives are priorities in the implementation of public health screening services. In the optimisation of image quality (IQ), radiographers play a major role. Between 1998 and 2009, the steering committee for mammography of a large population-based screening service in northern Italy undertook several audit checks of the imaging facilities. Read More

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Extreme Biomimetics: Designing of the First Nanostructured 3D Spongin-Atacamite Composite and its Application.

Adv Mater 2021 Jun 3:e2101682. Epub 2021 Jun 3.

Donostia International Physics Center (DIPC), Donostia-San Sebastián, 20018, Spain.

The design of new composite materials using extreme biomimetics is of crucial importance for bioinspired materials science. Further progress in research and application of these new materials is impossible without understanding the mechanisms of formation, as well as structural features at the molecular and nano-level. It presents a challenge to obtain a holistic understanding of the mechanisms underlying the interaction of organic and inorganic phases under conditions of harsh chemical reactions for biopolymers. Read More

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Proline oxidase silencing inhibits p53-dependent apoptosis in MCF-7 breast cancer cells.

Amino Acids 2021 Jun 4. Epub 2021 Jun 4.

Department of Medicinal Chemistry, Medical University of Bialystok, Mickiewicza 2D, 15-222, Bialystok, Poland.

Proline oxidase (POX) is mitochondrial proline-degrading enzyme of dual apoptosis/survival function. POX expression and proline availability are considered an underlying mechanism for differential POX functions. The mechanism for POX-dependent regulation of cell death/survival was studied in wild-type (MCF-7) and shRNA POX-silenced breast cancer cells (MCF-7). Read More

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Lost opportunities for mismatch repair (MMR) screening among minority women with endometrial cancer.

Sci Rep 2021 Jun 3;11(1):11712. Epub 2021 Jun 3.

Department of Pathology, University of Miami Miller School of Medicine, 1120 NW 14th Street, Miami, FL, 33136, USA.

Lynch Syndrome (LS) prevalence in underrepresented minorities are lacking. The objective of this study was to assess the prevalence of LS in a minority patient population. Secondary objectives included identifying factors associated with successful LS screening and to characterize clinicopathologic features. Read More

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Minimal residual disease assessment by multiparameter flow cytometry in transplant-eligible myeloma in the EMN02/HOVON 95 MM trial.

Blood Cancer J 2021 Jun 3;11(6):106. Epub 2021 Jun 3.

Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.

Minimal residual disease (MRD) by multiparameter flow cytometry (MFC) is the most effective tool to define a deep response in multiple myeloma (MM). We conducted an MRD correlative study of the EMN02/HO95 MM phase III trial in newly diagnosed MM patients achieving a suspected complete response before maintenance and every 6 months during maintenance. Patients received high-dose melphalan (HDM) versus bortezomib-melphalan-prednisone (VMP) intensification, followed by bortezomib-lenalidomide-dexamethasone (VRd) versus no consolidation, and lenalidomide maintenance. Read More

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Promoting Media Literacy Online: An Intervention on Performance and Appearance Enhancement Substances with Sport High School Students.

Int J Environ Res Public Health 2021 05 24;18(11). Epub 2021 May 24.

Department of Social and Developmental Psychology, "Sapienza" University of Rome, 00185 Rome, Italy.

The outbreak of coronavirus required adjustment regarding the delivery of interventions. Media literacy interventions are necessary to help people acquire relevant skills to navigate the complexities of media communications, and to encourage health-promoting behaviors. The present study aimed to promote a media literacy intervention regarding performance and appearance enhancement substances use in sports high school students. Read More

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AR-V7 in Metastatic Prostate Cancer: A Strategy beyond Redemption.

Int J Mol Sci 2021 May 24;22(11). Epub 2021 May 24.

Department of Health Sciences, University of Florence, 50139 Florence, Italy.

Metastatic prostate cancer is the most common cancer in males and the fifth cause of cancer mortality worldwide. Despite the major progress in this field, leading to the approval of novel anti-androgens, the prognosis is still poor. A significant number of patients acquire an androgen receptor splice variant 7 (AR-V7), which is constitutively activated and lacks the ligand-binding domain (LBD) while maintaining the nuclear localization signal and DNA-binding domain (DBD). Read More

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Unraveling the Relationship between Milk Yield and Quality at the Test Day with Rumination Time Recorded by a PLF Technology.

Animals (Basel) 2021 May 28;11(6). Epub 2021 May 28.

Centro di Ricerca Zootecnia e Acquacoltura, Consiglio per la Ricerca in Agricoltura e L'analisi Dell'economia Agraria (CREA), via Lombardo 11, 26900 Lodi, Italy.

The study aimed to estimate the components of rumination time (RT) variability recorded by a neck collar sensor and the relationship between RT and milk composition. Milk test day (TD) and RT data were collected from 691 cows in three farms. Daily RT data of each animal were averaged for 3, 7, and 10 days preceding the TD date (RT). Read More

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Hepatitis B Virus-Related Cryoglobulinemic Vasculitis: Review of the Literature and Long-Term Follow-Up Analysis of 18 Patients Treated with Nucleos(t)ide Analogues from the Italian Study Group of Cryoglobulinemia (GISC).

Viruses 2021 May 30;13(6). Epub 2021 May 30.

Rheumatology Clinic, Department of Medicine (DAME), ASUFC, University of Udine, 33100 Udine, Italy.

Hepatitis B virus (HBV) chronic infection causes progressive liver damage, although about 20% of patients develop extrahepatic manifestations such as cryoglobulinemic vasculitis (CV). Clinical manifestations range from mild to moderate (purpura, asthenia, arthralgia) to severe (leg ulcers, peripheral neuropathy, glomerulonephritis, non-Hodgkin lymphoma). A comprehensive review of therapeutic options for HBV-related CV is lacking. Read More

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Evaluation of Drug-Drug Interactions in EGFR-Mutated Non-Small-Cell Lung Cancer Patients during Treatment with Tyrosine-Kinase Inhibitors.

J Pers Med 2021 May 18;11(5). Epub 2021 May 18.

Medical Oncology Unit B, Policlinico Umberto I, Sapienza University of Rome, Viale del Policlinico, 155, 00161 Roma, Italy.

(1) Background. The onset of a drug-drug interaction (DDI) may affect treatment efficacy and toxicity of advanced non-small-cell lung cancer (aNSCLC) patients during epidermal growth factor receptor (EGFR) tyrosine-kinase inhibitor (TKI) use. Here we present the use of Drug-PIN (Personalized Interactions Network) software to detect DDIs in aNSCLC patients undergoing EGFR-TKIs. Read More

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The Motivational Underpinnings of Intentions to Use Doping in Sport: A Sample of Young Non-Professional Athletes.

Int J Environ Res Public Health 2021 May 19;18(10). Epub 2021 May 19.

Department of Psychology of Development and Socialisation Processes, "Sapienza" University of Rome, 00185 Rome, Italy.

Doping use is considered as a deviant behavior in sport contexts, and it is necessary to recognize preventive factors to shut down the negative consequences. We proposed that athletes experiencing loss of personal significance would be more prone to doping use intentions. This pathway should occur through the effect of the enhanced predominance of obsessive (vs. Read More

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An Instance Segmentation-Based Method to Obtain the Leaf Age and Plant Centre of Weeds in Complex Field Environments.

Sensors (Basel) 2021 May 13;21(10). Epub 2021 May 13.

College of Engineering, Northeast Agricultural University, Harbin 150030, China.

Leaf age and plant centre are important phenotypic information of weeds, and accurate identification of them plays an important role in understanding the morphological structure of weeds, guiding precise targeted spraying and reducing the use of herbicides. In this work, a weed segmentation method based on BlendMask is proposed to obtain the phenotypic information of weeds under complex field conditions. This study collected images from different angles (front, side, and top views) of three kinds of weeds (, barnyard grass (), and Medicus) in a maize field. Read More

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Monitoring Exotic Beetles with Inexpensive Attractants: A Case Study.

Insects 2021 May 17;12(5). Epub 2021 May 17.

World Biodiversity Association Onlus c/o NAT LAB Forte Inglese, Portoferraio, 57037 Livorno, Italy.

Detecting and monitoring exotic and invasive Coleoptera is a complex activity to implement, and citizen science projects can provide significant contributions to such plans. Bottle traps are successfully used in wildlife surveys and can also be adapted for monitoring alien species; however, a sustainable, large scale trapping plan must take into account the collateral catches of native species and thus minimize its impact on local fauna. In the present paper, we tested the use of bottles baited with standard food products that can be purchased in every supermarket and immediately used (apple cider vinegar, red wine, and 80% ethyl alcohol) in capturing exotic and invasive beetles in the area surrounding Malpensa Airport (Italy). Read More

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and in Wine Sequential Fermentation in Aeration Condition: Evaluation of Ethanol Reduction and Analytical Profile.

Foods 2021 May 11;10(5). Epub 2021 May 11.

Dipartimento Scienze della Vita e dell'Ambiente, Università Politecnica delle Marche, Via Brecce Bianche, 60131 Ancona, Italy.

In the last few decades, the increase of ethanol in wine, due to global climate change and consumers' choice is one of the main concerns in winemaking. One of the most promising approaches in reducing the ethanol content in wine is the use of non- yeasts in co-fermentation or sequential fermentation with . In this work, we evaluate the use of and in sequential fermentation under aeration condition with the aim of reducing the ethanol content with valuable analytical profile. Read More

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Aloe-emodin, a hydroxyanthracene derivative, is not genotoxic in an in vivo comet test.

Regul Toxicol Pharmacol 2021 May 29;124:104967. Epub 2021 May 29.

Department of Pharmacological and Biomolecular Sciences (DISFeB), Section of Toxicology and Risk Assessment, University of Milan, Milan, Italy.

Aloe-emodin, one of the molecules belonging to the group of hydroxyanthracene derivatives, was recently described as genotoxic in vivo. Indeed, the EFSA judged that aloe-emodin, together with other similar molecules (emodin and danthron) and extracts from the leaf of Aloe species containing hydroxyanthracene derivatives, could represent a risk factor for colorectal cancer mediated by a genotoxic effect. Given the marked uncertainty regarding the conclusions in the opinion of the EFSA ANS Panel and conflicts in the epidemiological data on which the opinion is based, a new in vivo study (in vivo alkaline comet assay in mice - OECD 489) was conducted to test the potential genotoxicity of aloe-emodin at doses of 250, 500, 1000 and 2000 mg/kg bw/day on preparations of single cells from the kidney and colon of treated male mice. Read More

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