3,401 results match your criteria gait deficits


Effects of total knee arthroplasty for primary knee osteoarthritis on postural balance: A systematic review.

Gait Posture 2021 Apr 30;89:139-160. Epub 2021 Apr 30.

Centre of Health and Sports Sciences (CEFID), State University of Santa Catarina, Florianópolis, Santa Catarina (UDESC), Brazil. Electronic address:

Background: Knee osteoarthritis is often related to physical function impairment. Although total knee arthroplasty is considered effective for advanced cases of knee osteoarthritis, its effects on postural balance is a topic of debate.

Research Question: What are the effects of total knee arthroplasty for primary knee osteoarthritis on postural balance compared to preoperative status and/or to healthy controls?. Read More

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Effects of lower extremity constraint-induced movement therapy on gait and balance of chronic hemiparetic patients after stroke: description of a study protocol for a randomized controlled clinical trial.

Trials 2021 Jul 19;22(1):463. Epub 2021 Jul 19.

Neurology/Neuroscience program, Federal University of São Paulo - UNIFESP, Botucatu street, 862 - 5° floor Edifico Ciências Biomédicas, São Paulo, Brazil.

Background: Protocols involving intensive practice have shown positive outcomes. Constraint induced movement therapy (CIT) appears to be one of the best options for better outcomes in upper limb rehabilitation, but we still have little data about lower extremity constraint-induced movement therapy (LE-CIT) and its effects on gait and balance.

Objective: To evaluate the effects of an LE-CIT protocol on gait functionality and balance in chronic hemiparetic patients following a stroke. Read More

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Best Practices in the Clinical Management of Progressive Supranuclear Palsy and Corticobasal Syndrome: A Consensus Statement of the CurePSP Centers of Care.

Front Neurol 2021 1;12:694872. Epub 2021 Jul 1.

Neurology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.

Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS; the most common phenotype of corticobasal degeneration) are tauopathies with a relentless course, usually starting in the mid-60s and leading to death after an average of 7 years. There is as yet no specific or disease-modifying treatment. Clinical deficits in PSP are numerous, involve the entire neuraxis, and present as several discrete phenotypes. Read More

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Running Biomechanics Before Injury and 1 Year After Anterior Cruciate Ligament Reconstruction in Division I Collegiate Athletes.

Am J Sports Med 2021 Jul 14:3635465211026665. Epub 2021 Jul 14.

Department of Orthopedics and Rehabilitation, University of Wisconsin-Madison, Madison, Wisconsin, USA.

Background: Preinjury running biomechanics are an ideal comparator for quantifying recovery after anterior cruciate ligament (ACL) reconstruction (ACLR), allowing for assessments within the surgical and nonsurgical limbs. However, availability of preinjury running biomechanics is rare and has been reported in case studies only.

Purpose/hypothesis: The purpose of this study was to determine if running biomechanics return to preinjury levels within the first year after ACLR among collegiate athletes. Read More

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Lentiform fork sign in a uremic patient after inadvertent exposure to metformin.

Clin Toxicol (Phila) 2021 Jul 14:1-2. Epub 2021 Jul 14.

Division of Nephrology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.

This case report describes a 56-year-old woman receiving regular hemodialysis for three years who presented with an unsteady gait for one month, dysarthria, and frequent choking on liquids for two weeks. Brain MRI revealed a characteristic "lentiform fork sign" with hyperintense T2W/FLAIR signal in the bilateral lentiform nuclei and restricted diffusion in bilateral globus pallidus. She was inadvertently prescribed metformin 1,000 mg per day one month ago by a physician who was unaware of her end-stage kidney disease. Read More

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Long-Term Use of a Sensory Prosthesis Improves Function in a Patient With Peripheral Neuropathy: A Case Report.

Front Neurol 2021 23;12:655963. Epub 2021 Jun 23.

Department of Rehabilitation Medicine, Medical School, University of Minnesota, Minneapolis, MN, United States.

Peripheral neuropathy (PN) can result in either partial or complete loss of distal sensation resulting in an increased fall risk. Walkasins® uses a shoe insert to detect the magnitude and direction of sway and sends signals to a leg unit that provides sensory balance cues. The objective of this case report is to describe the long-term influence of the Walkasins® lower limb sensory neuroprosthesis on balance and gait for an individual with diabetic PN. Read More

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Cognitive Load Impairs Time to Initiate and Complete Shooting Tasks in ROTC Members.

Mil Med 2021 Jul 9. Epub 2021 Jul 9.

School of Applied Health Sciences and Wellness, College of Health Sciences and Professions, Ohio University, Athens, OH 45701, USA.

Introduction: Multitasking typically requires an individual to simultaneously process cognitive information while performing a motor task. Cognitive motor interference (CMi) is encountered when cognitive challenges negatively impact motor task performance. Military personnel encounter cognitively taxing situations, especially during combat or other tactical performance scenarios, which may lead to injury or motor performance deficits (i. Read More

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Fenestration of intracranial neurenteric cyst: A case report.

Surg Neurol Int 2021 14;12:287. Epub 2021 Jun 14.

Department of Neurosurgery, University of New Mexico Hospital, Albuquerque, New Mexico, United States.

Background: Neurenteric cysts are rare congenital lesions of endodermal origin which result from the failure of the neurenteric canal to close during embryogenesis. The majority of neurenteric cysts occur in the spinal cord, though in rare instances can occur intracranially, typically in the posterior fossa anterior to the pontomedullary junction (80%) or in the supratentorial region adjacent to the frontal lobes (20%).

Case Description: We present the case of a 75-year-old woman with an extra-axial cystic lesion centered in the premedullary cistern causing brainstem compression. Read More

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Gait Difficulties and Postural Instability in Adrenoleukodystrophy.

Front Neurol 2021 17;12:684102. Epub 2021 Jun 17.

Department of Neurology, Massachusetts General Hospital, Boston, MA, United States.

Gait and balance difficulties are among the most common clinical manifestations in adults with X-linked adrenoleukodystrophy, but little is known about the contributions of sensory loss, motor dysfunction, and postural control to gait dysfunction and fall risk. To quantify gait and balance deficits in both males and females with adrenoleukodystrophy and evaluate how environmental perturbations (moving surfaces and visual surrounds) affect balance and fall risk. We assessed sensory and motor contributions to gait and postural instability in 44 adult patients with adrenoleukodystrophy and 17 healthy controls using three different functional gait assessments (25 Foot Walk test, Timed Up and Go, and 6 Minute Walk test) and computerized dynamic posturography. Read More

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Low-Expressing Synucleinopathy Mouse Models Based on Oligomer-Forming Mutations and C-Terminal Truncation of α-Synuclein.

Front Neurosci 2021 17;15:643391. Epub 2021 Jun 17.

Genes and Behavior Department, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.

α-synuclein (αSyn) is the main protein component of Lewy bodies, intracellular inclusions found in the brain of Parkinson's disease (PD) patients. Neurotoxic αSyn species are broadly modified post-translationally and, in patients with genetic forms of PD, carry genetically encoded amino acid substitutions. Mutations and C-terminal truncation can increase αSyn oligomerization and fibrillization. Read More

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The effect of shoe cushioning on gait and balance in females with multiple sclerosis.

Exp Brain Res 2021 Jul 1. Epub 2021 Jul 1.

Department of Health and Exercise Science, Colorado State University, Room 220 Moby Complex, 951 Plum Street, Fort Collins, CO, 80523-1582, USA.

Gait and balance deficits are significant concerns for people with multiple sclerosis (MS). Shoe cushioning can influence mobility and balance, but its effect on walking and balance remains unknown in MS. This study aimed to determine how shoe cushioning affects gait and balance in females with MS (FwMS). Read More

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Instrumented Gait Analysis to Identify Persistent Deficits in Gait Stability in Adults With Chronic Vestibular Loss.

JAMA Otolaryngol Head Neck Surg 2021 Jul 1. Epub 2021 Jul 1.

Department of Orthopedics and Rehabilitation, University of Wisconsin-Madison.

Importance: Regaining the ability to walk safely is a high priority for adults with vestibular loss. Thus, practitioners need comprehensive knowledge of vestibulopathic gait to design, provide, and/or interpret outcomes of interventions. To date, few studies have characterized the effects of vestibular loss on gait. Read More

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The effect of scoliosis support orthosis bracing on adult spinal deformity patients: evaluation of gait and dynamic balance.

Stud Health Technol Inform 2021 Jun;280:115-120

Old Dominion University, Norfolk, Viriginia, USA.

Non-operative treatment is regarded as the first-line therapy for patients with adult spinal deformity (ASD) without neurologic deficits or significant impairment. While there is high-level evidence supporting the use of rigid bracing in adolescent idiopathic scoliosis, there is a paucity of literature pertaining to the use of scoliosis support orthosis (SSO) in ASD patients. To investigate the impact of an SSO on pain, gait parameters, and functional balance measures in symptomatic ASD patients. Read More

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Does improved radiographic alignment truly enhance dynamic functional balance?

Stud Health Technol Inform 2021 Jun;280:46-52

Texas Back Institute, Plano, TX, USA.

Prospective, concurrent-cohort study. To establish the relationship between radiographic alignment parameters and functional CoE measurements at one week before and at three months after realignment surgery in ADS patients. Adult degenerative scoliosis (ADS) represents a significant healthcare burden with exceedingly high and increasing prevalence, particularly among the elderly. Read More

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Bracing: Upper and Lower Limb Orthoses.

Phys Med Rehabil Clin N Am 2021 Aug 20;32(3):509-526. Epub 2021 May 20.

LPG Physiatry, 765 Allens Avenue, Suite 110, Providence, RI 02905, USA. Electronic address:

The goals of bracing in polio and postpolio are to optimize joint position and support weak muscles with the goal of reducing falls, reducing deformities, and optimizing energy conservation. Orthoses are primarily used in the lower extremities to optimize gait. Less frequently, upper extremity orthoses are required. Read More

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Visio-Vestibular Deficits in Healthy Child and Adolescent Athletes.

Clin J Sport Med 2021 Jun 22. Epub 2021 Jun 22.

Center for Injury Research and Prevention, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; Division of Emergency Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; School of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania; and Sports Medicine and Performance Center, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

Objective: To determine the relationship between patient characteristics and performance on the visio-vestibular examination (VVE) in a cohort of healthy youth athletes and explore the potential association between the VVE and other standardized concussion batteries.

Design: Cross-sectional.

Setting: Suburban middle and high school. Read More

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Selective optogenetic stimulation of glutamatergic, but not GABAergic, vestibular nuclei neurons induces immediate and reversible postural imbalance in mice.

Prog Neurobiol 2021 Jun 23:102085. Epub 2021 Jun 23.

Shenzhen Key Lab of Neuropsychiatric Modulation and Collaborative Innovation Center for Brain Science, Guangdong Provincial Key Laboratory of Brain Connectome and Behavior, CAS Center for Excellence in Brain Science and Intelligence Technology, The Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen, 518055, China. Electronic address:

Glutamatergic and GABAergic neurons represent the neural components of the medial vestibular nuclei. We assessed the functional role of glutamatergic and GABAergic neuronal pathways arising from the vestibular nuclei (VN) in the maintenance of gait and balance by optogenetically stimulating the VN in VGluT2-cre and GAD2-cre mice. We demonstrate that glutamatergic, but not GABAergic VN neuronal subpopulation is responsible for immediate and strong posturo-locomotor deficits, comparable to unilateral vestibular deafferentation models. Read More

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Localized chondro-ossification underlies joint dysfunction and motor deficits in the mouse model of osteogenesis imperfecta.

Proc Natl Acad Sci U S A 2021 Jun;118(25)

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030;

Osteogenesis imperfecta (OI) is a genetic disorder that features wide-ranging defects in both skeletal and nonskeletal tissues. Previously, we and others reported that loss-of-function mutations in FK506 Binding Protein 10 () lead to skeletal deformities in conjunction with joint contractures. However, the pathogenic mechanisms underlying joint dysfunction in OI are poorly understood. Read More

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Motor dual task with eyes closed improves postural control in patients with functional motor disorders: A posturographic study.

Gait Posture 2021 Jun 11;88:286-291. Epub 2021 Jun 11.

Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy. Electronic address:

Background: Functional motor disorders (FMD) are highly disabling neurological conditions in which postural control deficits increase the risk of falls and disability in performing daily living activities. Scattered evidence suggests that such disturbances may depend on abnormal attentional focus and might improve with distraction.

Research Question: How do motor and cognitive dual tasks performed under two different sensory conditions shape postural control in patients with FMD. Read More

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The effect of powered ankle prostheses on muscle activity during walking.

J Biomech 2021 Jul 11;124:110573. Epub 2021 Jun 11.

School of Kinesiology, University of Michigan, Ann Arbor, MI, USA; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA. Electronic address:

Individuals with transtibial amputation (TTA) walk with greater muscle activity and metabolic costs than non-amputees. Powered prostheses aim to address these deficits by replicating the active function of the biological ankle. The purpose of this study was to determine if people with TTA alter muscle activity when walking with a powered prosthesis, and if this change relates to changes in metabolic costs. Read More

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Deficits in Geriatric Assessment Associate With Disease Activity and Burden in Older Patients With Inflammatory Bowel Disease.

Clin Gastroenterol Hepatol 2021 Jun 19. Epub 2021 Jun 19.

Department of Gastroenterology and Hepatology, Leiden University Medical Centre, Leiden, the Netherlands.

Background & Aims: We aimed to perform geriatric assessment in older patients with inflammatory bowel disease (IBD) to evaluate which IBD characteristics associate with deficits in geriatric assessment and the impact of deficits on disease burden (health-related quality of life).

Methods: A prospective multicenter cohort study including 405 consecutive outpatient patients with IBD aged ≥65 years. Somatic domain (comorbidity, polypharmacy, malnutrition), impairments in (instrumental) activities of daily living, physical capacity (handgrip strength, gait speed), and mental (depressive symptoms, cognitive impairment) and social domain (life-partner) were assessed. Read More

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Changes in Metabolic Activity and Gait Function by Dual-Task Cognitive Game-Based Treadmill System in Parkinson's Disease: Protocol of a Randomized Controlled Trial.

Front Aging Neurosci 2021 4;13:680270. Epub 2021 Jun 4.

Department of Human Anatomy and Cell Science, University of Manitoba, Winnipeg, MB, Canada.

Balance and gait impairments, and consequently, mobility restrictions and falls are common in Parkinson's disease (PD). Various cognitive deficits are also common in PD and are associated with increased fall risk. These mobility and cognitive deficits are limiting factors in a person's health, ability to perform activities of daily living, and overall quality of life. Read More

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[Paraneoplastic sensorimotor neuropathy with anti-Hu antibody associated with gallbladder carcinoma].

Rinsho Shinkeigaku 2021 Jun 18. Epub 2021 Jun 18.

Department of Neurology, Saiseikai Kumamoto Hospital, Kumamoto.

A 78-year-old woman experienced gait disturbance. She became unable to walk within a month. On admission, her cranial nerves were normal. Read More

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Contributions of PCSS, BESS, Tandem Gait, and Romberg Test for Identifying Balance Deficits in Pediatric Concussions.

J Head Trauma Rehabil 2021 Jun 15. Epub 2021 Jun 15.

Feinberg School of Medicine, Northwestern University, Chicago, Illinois (Drs Patel and LaBella); and Division of Orthopaedic Surgery and Sports Medicine, Lurie Children's Hospital, Chicago, Illinois (Dr LaBella).

Objective: Balance deficits are common after concussions in pediatric patients. This study evaluates 3 clinical tools for identifying postconcussion balance deficits in a pediatric population: (1) Post-Concussion Symptom Scale (PCSS); (2) Balance Error Scoring System (BESS); and (3) physical examination measures of balance: tandem gait (TG) and Romberg test.

Setting: Data were collected in a tertiary care outpatient pediatric sports medicine clinic. Read More

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Treatment of Severe Ankle and Hindfoot Deformity: Technique Using Femoral Head Allograft for Tibiotalocalcaneal Fusion Using a Cup-and-Cone Reamer.

Arthrosc Tech 2021 May 6;10(5):e1187-e1195. Epub 2021 Apr 6.

Valley Hospital Medical Center, Las Vegas, Nevada, U.S.A.

Limb shortening due to structural bone loss in tibiotalocalcaneal arthrodesis is a concern that can negatively impact the patient's gait and weight-bearing. To aid in preventing the risk of limb shortening, the use of a femoral head allograft and intramedullary nail in tibiotalocalcaneal arthrodesis has been shown to successfully preserve limb length in patients with structural bone deficits. We present our technique using a femoral head allograft with a cup-and-cone reamer for the treatment of severe ankle and hindfoot deformity. Read More

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The application of principal component analysis to characterize gait and its association with falls in multiple sclerosis.

Sci Rep 2021 Jun 17;11(1):12811. Epub 2021 Jun 17.

College of Health Solutions, Arizona State University, 425 N 5th St., Phoenix, AZ, 85282, USA.

People with multiple sclerosis (PwMS) demonstrate gait impairments that are related to falls. However, redundancy exists when reporting gait outcomes. This study aimed to develop an MS-specific model of gait and examine differences between fallers and non-fallers. Read More

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Effects of Concurrent Tasks on Gait Performance in Children With Traumatic Brain Injury Versus Children With Typical Development.

Ann Rehabil Med 2021 Jun 14;45(3):186-196. Epub 2021 Jun 14.

Clinical and Rehabilitation Exercise Research Group, Faculty of Health Sciences, Universiti Teknologi MARA - Puncak Alam Campus, Selangor, Malaysia.

Objective: To investigate how gait parameters in children with traumatic brain injury (TBI) versus typically developing (TD) children are influenced by secondary concurrent tasks and examine the correlations between gait parameters and attention and balance in children with TBI.

Methods: Sixteen children with TBI (mean age, 11.63±1. Read More

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The importance of biomechanical assessment after Return to Play in athletes with ACL-Reconstruction.

Gait Posture 2021 Jun 8;88:240-246. Epub 2021 Jun 8.

Department of Basic Medical Sciences, Neuroscience and Sense Organs, School of Medicine, University of Bari "Aldo Moro", AOU Consorziale Policlinico, Piazza Giulio Cesare 11, 70124 Bari, Italy; Orthopaedic & Trauma Unit, AOU Consorziale Policlinico, Piazza Giulio Cesare 11, 70124 Bari, Italy.

Background: Barriers to successful return to previous level of activity following Anterior Cruciate Ligament Reconstruction (ACLR) are multifactorial and recent research suggests that athletic performance deficits persist after completion of the rehabilitation course in a large percentage of patients.

Research Question: Do technology-based biomechanical assessments reveal underneath differences in both recreational and competitive athletes in Return to Play after ACL-Reconstruction?

Methods: Thirty soccer athletes (26.9 ± 5. Read More

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Strategies for Gait Retraining in a Collegiate Runner with Transfemoral Amputation: A Case Report.

Int J Sports Phys Ther 2021 Jun 2;16(3):862-869. Epub 2021 Jun 2.

University of Rochester Medical Center.

Background: More than fifty percent of people with limb amputations participate in sports or physical activity following amputation. Athletes with limb amputations may face additional challenges including phantom limb pain (PLP), psychological barriers, prosthetic complications, and gait abnormalities. Prevalence of PLP in the general amputee population is estimated to be as high as 85%. Read More

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Kinematic Characteristics of Male Runners With a History of Recurrent Calf Muscle Strain Injury.

Int J Sports Phys Ther 2021 Jun 1;16(3):732-740. Epub 2021 Jun 1.

University of Salford.

Background: Calf muscle strain injuries are a common running injury affecting male runners and are known to have high reoccurrence rates. Currently, limited evidence exists investigating factors associated with this injury with no previous study investigating the running kinematics of male runners with a history of repeat calf muscle strain injuries.

Purpose: To investigate whether male runners with a history of repeat calf muscle strain injury demonstrate differences in stance phase running kinematics when compared to healthy controls. Read More

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