3 results match your criteria gadolinium excesses

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Compound-specific recording of gadolinium pollution in coastal waters by great scallops.

Sci Rep 2019 05 29;9(1):8015. Epub 2019 May 29.

LaTIM (INSERM UMR 1101) Université de Bretagne Occidentale. 22, avenue C. Desmoulins, 29238, Brest Cedex 3, France.

Gadolinium-based contrast agents (GBCAs), routinely used in magnetic resonance imaging (MRI), end up directly in coastal seawaters where gadolinium concentrations are now increasing. Because many aquatic species could be sensitive to this new pollution, we have evaluated the possibility of using shellfish to assess its importance. Gadolinium excesses recorded by scallop shells collected in Bay of Brest (Brittany, France) for more than 30 years do not reflect the overall consumption in GBCAs, but are largely controlled by one of them, the gadopentetate dimeglumine. Read More

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Capillary electrophoretic determination of Ga(III) based on the formation of a heteropolyoxomolybdate complex.

J Chromatogr A 2003 Apr;993(1-2):211-5

Department of Chemistry, Faculty of Science, Kobe University, Nada, Kobe 657-8501, Japan.

A novel capillary electrophoretic (CE) method was developed for the determination of Ga(III). The so-called Anderson-type [GaMo6O24H6]3- complex was readily formed by the reaction of Mo(VI) with Ga(III) in 0.050 M monochloroacetate buffer (pH 2. Read More

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Synthesis of Lipophilic Paramagnetic Contrast Agents.

J Org Chem 1999 Apr;64(8):2683-2689

Roger Adams Laboratory, Department of Chemistry, University of Illinois, Urbana, Illinois 61801.

The facile, high-yielding synthesis of a series of macrocycles 7a-k in 75-100% yield is reported. The transformation of these compounds to their carboxymethylated analogues 8a-k in 75-90% yield and subsequent gadolinium complexes 9a-k provides a series of homologous neutral paramagnetic contrast agents (PCAs) with tunable lipophilicity. Alkylated cationic intermediates 6a-k are prepared in yields of 72-94% from glyoxal adduct of cyclen (5) and slight excesses of alkyl iodides. Read More

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