1,437,086 results match your criteria functional cres

[Liposuction with consequences: what to consider when using prilocaine].

Handchir Mikrochir Plast Chir 2021 Apr 16. Epub 2021 Apr 16.

Spital Thurgau AG, Hand- und Plastische Chirurgie.

Aetiologically, prilocaine-induced methaemoglobinaemia is a rare form of acquired methaemoglobinaemia, which occurs rarely in the first place. The following report highlights a potentially dangerous complication arising after application of prilocaine during liposuction.A young female visited the Accident and Emergency Department following a pre-syncopal fall. Read More

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Thalamic Deep Brain Stimulation for Spasmodic Dysphonia: A Phase I Prospective Randomized Double-Blind Crossover Trial.

Neurosurgery 2021 Apr 16. Epub 2021 Apr 16.

Division of Otolaryngology, University of British Columbia, Vancouver, Canada.

Background: Adductor spasmodic dysphonia (SD) is a dystonia of the vocal folds causing difficulty with speech. The current standard of care is repeated botulinum toxin injections to weaken the adductor muscles. We sought to ameliorate the underlying neurological cause of SD with a novel therapy-deep brain stimulation (DBS). Read More

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Dual Regeneration of Muscle and Nerve by Intramuscular Infusion of Mitochondria in a Nerve Crush Injury Model.

Neurosurgery 2021 Apr 16. Epub 2021 Apr 16.

Institute of Biomedical Sciences, National Chung-Hsing University, Taichung, Taiwan.

Background: Peripheral nerve injuries result in muscle denervation and apoptosis of the involved muscle, which subsequently reduces mitochondrial content and causes muscle atrophy. The local injection of mitochondria has been suggested as a useful tool for restoring the function of injured nerves or the brain.

Objective: To determine outcomes following the administration of isolated mitochondria into denervated muscle after nerve injury that have not been investigated. Read More

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Diet-induced vitamin D deficiency reduces skeletal muscle mitochondrial respiration.

J Endocrinol 2021 May;249(2):113-124

Mitochondrial Metabolism and Ageing Laboratory, Garvan Institute of Medical Research, Sydney, New South Wales, Australia.

Vitamin D deficiency is associated with symptoms of skeletal muscle myopathy including muscle weakness and fatigue. Recently, vitamin D-related metabolites have been linked to the maintenance of mitochondrial function within skeletal muscle. However, current evidence is limited to in vitro models and the effects of diet-induced vitamin D deficiency upon skeletal muscle mitochondrial function in vivo have received little attention. Read More

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Awake CT-guided percutaneous stylomastoid foramen puncture and radiofrequency ablation of facial nerve for treatment of hemifacial spasm.

J Neurosurg 2021 Apr 16:1-7. Epub 2021 Apr 16.

2Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University, Palo Alto, California.

Objective: Hemifacial spasm (HFS) is a debilitating neuromuscular disorder with limited treatment options. The current study describes a novel minimally invasive procedure that provided effective and sustained relief for patients with HFS. The authors provide a detailed description of the awake CT-guided percutaneous radiofrequency ablation (RFA) of the facial nerve for treatment of HFS, and they examine its clinical efficacy. Read More

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Targeting accuracy of robot-assisted deep brain stimulation surgery in childhood-onset dystonia: a single-center prospective cohort analysis of 45 consecutive cases.

J Neurosurg Pediatr 2021 Apr 16:1-11. Epub 2021 Apr 16.

1Department of Neurosurgery, King's College Hospital NHS Foundation Trust, London.

Objective: Deep brain stimulation (DBS) is an established treatment for pediatric dystonia. The accuracy of electrode implantation is multifactorial and remains a challenge in this age group, mainly due to smaller anatomical targets in very young patients compared to adults, and also due to anatomical abnormalities frequently associated with some etiologies of dystonia. Data on the accuracy of robot-assisted DBS surgery in children are limited. Read More

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Long-term functional and quality of life outcomes in laryngectomized patients after successful voice restoration using tracheoesophageal prostheses.

Surg Oncol 2021 Apr 13;38:101580. Epub 2021 Apr 13.

Department of Statistics, Centre Antoine Lacassagne, Université Côte d'Azur, Nice, France.

Objective: To assess long-term functional and quality of life (QoL) outcomes and their predictive factors in laryngectomized patients after successful voice restoration using tracheoesophageal prostheses (TEP).

Methods: This cross-sectional study was conducted in alive and disease-free patients at least 1 year after total laryngectomy ± partial pharyngectomy. Patients completed the European Organization for Research and Treatment of Cancer (EORTC) Core (QLQ-C30) and Head and Neck Cancer (QLQ-H&N35) QoL questionnaires, the Voice Handicap Index (VHI-10) questionnaire and the Hospital Anxiety and Depression Scale (HADS). Read More

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Interaction of epoxy-based hydrogels and water: A molecular dynamics simulation study.

J Mol Graph Model 2021 Apr 5;106:107915. Epub 2021 Apr 5.

Interdisciplinary Center for Nanotoxicity, Department of Chemistry, Physics and Atmospheric Sciences, Jackson State University, Jackson, MS, 39217, USA. Electronic address:

Biomaterials play a crucial role in tissue engineering as a functional replacement, regenerative medicines, supportive scaffold for guided tissue growth, and drug delivery devices. The term biomaterial refers to metals, ceramics, and polymers account for the vast majority. In the case of polymers, hydrogels have emerged as active materials for an immense variety of applications. Read More

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Bonding a titanium plate and soft tissue interface by using an adhesive bone paste composed of α-tricalcium phosphate and α-cyclodextrin/nonanyl group-modified poly(vinyl alcohol) inclusion complex.

Colloids Surf B Biointerfaces 2021 Apr 9;203:111757. Epub 2021 Apr 9.

Polymers and Biomaterials Field, Research Center for Functional Materials, National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki, 305-0044, Japan. Electronic address:

Adhesive bone pastes for dental implants and soft tissue interfaces were developed using α-tricalcium phosphate (α-TCP) and α-cyclodextrin (α-CD)/nonanyl group-modified poly(vinyl alcohol) (C9-PVA) inclusion complex solution (ICS). The thixotropic solution of α-CD/C9-PVA ICS was prepared by mixing α-CD and C9-PVA in deionized water. The α-CD/C9-PVA bone paste led to the highest bonding and shear adhesion between commercial pure titanium plates and soft tissue like collagen casing. Read More

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Physician practice variation in head and neck cancer therapy: Results of a national survey.

Oral Oncol 2021 Apr 13;117:105293. Epub 2021 Apr 13.

Service d'otorhinolaryngologie et chirurgie cervico-faciale, Institut Universitaire du Cancer de Toulouse-Oncopole, Institut Claudius Regaud, 1avenue Hubert Curien, 31100 Toulouse, France. Electronic address:

Objectives: Choice between surgical or medical treatments in head and neck cancer depends of many patient-related and disease-related factors. We investigated how patients' socioeconomic status and practitioners' specialty could affect medical decision-making.

Materials And Methods: We conducted a cross-sectional online, nationwide survey, send to surgeons, oncologists and radiotherapists specialized in head and neck oncology. Read More

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The benefit of intravenous thrombolysis prior to mechanical thrombectomy within the therapeutic window for acute ischemic stroke.

Clin Imaging 2021 Apr 5;79:3-7. Epub 2021 Apr 5.

Northwestern University Feinberg School of Medicine, Department of Radiology, 676 N St Clair St, Chicago, IL 60611, United States of America.

The increase in risk for acute ischemic stroke (AIS) with age is well established. If not treated properly and promptly, AIS can result in permanent neurological damage and even death. This literature review assesses the clinical outcomes of AIS patients treated with both intravenous thrombolysis (IVT) prior to mechanical thrombectomy (MT) compared to those treated solely with mechanical thrombectomy. Read More

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Patient Characteristics and Outcomes Associated with Decline in Stroke Volumes During the Early COVID-19 Pandemic.

J Stroke Cerebrovasc Dis 2020 Dec 26;30(6):105569. Epub 2020 Dec 26.

Department of Neurointerventional Surgery, Ascension Columbia St. Mary's Hospital, Milwaukee, WI. Electronic address:

Background And Purpose: Delayed evaluation of stroke may contribute to COVID-19 pandemic-related morbidity and mortality. This study evaluated patient characteristics, process measures and outcomes associated with the decline in stroke presentation during the early pandemic.

Methods: Volumes of stroke presentations, intravenous thrombolytic administrations, and mechanical thrombectomies from 52 hospitals from January 1-June 30, 2020 were analyzed with piecewise linear regression and linear spline models. Read More

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December 2020

Dipyridyl-substituted thiosemicarbazone as a potent broad-spectrum inhibitor of metallo-β-lactamases.

Bioorg Med Chem 2021 Apr 8;38:116128. Epub 2021 Apr 8.

Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education, College of Chemistry and Materials Science, Northwest University, Xi'an 710127, PR China. Electronic address:

To combat the superbug infection caused by metallo-β-lactamases (MβLs), a dipyridyl-substituted thiosemicarbazone (DpC), was identified to be the broad-spectrum inhibitor of MβLs (NDM-1, VIM-2, IMP-1, ImiS, L1), with an IC value in the range of 0.021-1.08 µM. Read More

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YTHDF1-regulated expression of TEAD1 contributes to the maintenance of intestinal stem cells.

Biochem Biophys Res Commun 2021 Apr 13;557:85-89. Epub 2021 Apr 13.

Sir Run-Run Shaw Hospital, and Institute of Environmental Medicine, Zhejiang University School of Medicine, Hangzhou, China. Electronic address:

N6-methyladenosine (mA) mRNA modification has been defined as a crucial regulator in various biological processes. Recent studies indicated an essential role of YTHDF1, an mA reader, in the maintenance of intestinal stem cells (ISCs), while the detailed mechanism remains to be explored. By searching our mA sequencing, RNA sequencing, and ribosome profiling data, we identified the transcriptional enhanced associate domain 1 (TEAD1) as a direct target of YTHDF1. Read More

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Semi-coherent cation-rich Mn-Cu oxides heterostructures as cathode for novel aqueous potassium dual-ion energy storage devices.

J Colloid Interface Sci 2021 Apr 5;597:75-83. Epub 2021 Apr 5.

Guangxi Key Laboratory of Electrochemical and Magneto-chemical Functional Materials, Department of Chemistry and Biological Engineering, Guilin University of Technology, Guilin 541004, China; Guangdong Institute of Semiconductor Industrial Technology, Guangdong Academy of Science, Guangzhou 510650, China; Siyuan Laboratory, Guangdong Provincial Engineering Technology Research Center of Vacuum Coating Technologies and New Materials, Department of Physics, Jinan University, Guangzhou 510632, China. Electronic address:

In this work, combining both advantages of aqueous energy storage systems (ESS) and conventional dual-ion ESS, a novel aqueous dual-ion ESS is developed based on K and OH electrochemistry by employing semi-coherent KMnO-CuO (sc-Mn-Cu) cathode. Profting from the elaborate design, the electrolyte and cathode simultaneously act as source of cations. In the novel aqueous dual-ion ESS configuration, the dependence of the performance on the electrolyte salt concentration is reduced and the sc-Mn-Cu cathode can host OH with lower working potentials by conversion mechanism. Read More

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Molecular engineering of carbon nitride towards photocatalytic H evolution and dye degradation.

J Colloid Interface Sci 2021 Mar 31;597:39-47. Epub 2021 Mar 31.

Department of Chemistry, Sri Siddhartha Institute of Technology, Tumkur 572105, Karnataka, India. Electronic address:

The development of superior heterogeneous catalyst for hydrogen (H) evolution is a significant feature and challenging for determining the energy and environmental crises. However, the dumping of numerous lethal colorants (dye) as of textile manufacturing has fascinated widespread devotion-aimed water pollution anticipation and treatment. In this regard, a photocatalytic H evolution by visible light using low-dimensional semiconducting materials having pollutant degradable capacity for Rhodamine B dyes (RhB) has been anticipated as a route towards environmental aspect. Read More

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A g-CN self-templated preparation of N-doped carbon nanosheets@Co-CoO/Carbon nanotubes as high-rate lithium-ion batteries' anode materials.

J Colloid Interface Sci 2021 Apr 5;597:1-8. Epub 2021 Apr 5.

Key Laboratory of Functional Small Organic Molecule, Ministry of Education, College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang 330022, China. Electronic address:

A novel N-doped graphene-like carbon nanosheets (CNs) and carbon nanotubes (CNTs)-encapsulated Co-CoO nanoparticles (NPs) (CN@Co-CoO/CNTs) were synthesized successfully by a simple hydrothermal and annealing method with graphite carbon nitride (g-CN) as self-template. By annealing Co/g-CN under N atmosphere, g-CN was transformed into CN/CNTs, and Co was reduced into CoNPs which were embedded in CNs. Further annealing in air, a shell of CoO was formed around CoNPs. Read More

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Are cadmium and lead levels linked to the development of anxiety and depression? - A systematic review of observational studies.

Ecotoxicol Environ Saf 2021 Apr 13;216:112211. Epub 2021 Apr 13.

Department of Nursing, Faculty of Health Sciences, Pomeranian Medical University in Szczecin, 48 Żołnierska St., 71-210 Szczecin, Poland. Electronic address:

The aim of this systematic review was to assess if cadmium and lead levels are linked to anxiety and depression. A systematic literature search was conducted to identify observational trials evaluating the impact of cadmium and lead on the incidence and phenotype of depression and anxiety. The search identified 1059 records. Read More

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A microwave irradiation-persulfate-formate system for achieving the detoxification and alkali-activated composite geopolymerization of the chromate-contaminated soil.

Ecotoxicol Environ Saf 2021 Apr 13;217:112233. Epub 2021 Apr 13.

School of Materials Engineering, Changshu Institute of Technology, 215500, China.

A microwave (MA) irradiation-persulfate-formate system was constructed to detoxify Cr contamination and solidify the geopolymerization of the alkali-activated composite material. Three series of experiments were correspondingly conducted to evaluate the treatment for the chromate-contaminated soil. The changes in the molar ratios of formate to persulfate and the mass rates of fortifier to soil led to a significantly greater reduction of Cr in the detoxification experiments. Read More

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New femoral remains of Nacholapithecus kerioi: Implications for intraspecific variation and Miocene hominoid evolution.

J Hum Evol 2021 Apr 13;155:102982. Epub 2021 Apr 13.

Kyoto University, Kyoto, 606-8502, Japan.

The middle Miocene stem kenyapithecine Nacholapithecus kerioi (16-15 Ma; Nachola, Kenya) is represented by a large number of isolated fossil remains and one of the most complete skeletons in the hominoid fossil record (KNM-BG 35250). Multiple fieldwork seasons performed by Japanese-Kenyan teams during the last part of the 20th century resulted in the discovery of a large sample of Nacholapithecus fossils. Here, we describe the new femoral remains of Nacholapithecus. Read More

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Adsorption and reduction of Cr(VI) from aqueous solution using cost-effective caffeic acid functionalized corn starch.

Chemosphere 2021 Apr 10;279:130539. Epub 2021 Apr 10.

School of Life Science, Shaoxing University, Huancheng West Road 508, Shaoxing, 312000, PR China. Electronic address:

Herein, a potential bio-adsorbent (DACS-CA) was formed via immobilizing caffeic acid (CA) on dialdehyde corn starch (DACS) for Cr(VI) removal. The characterization techniques such as IR, Raman, XPS and C NMR were performed to analyze surface elements and functional groups on the as-prepared sorbents. Batch experiments revealed that the maximum Cr(VI) removal amount (96. Read More

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Self-preference music for gagging patient: Effect on physiology and oral health-related quality of life during dental impression.

Complement Ther Clin Pract 2021 Apr 13;43:101392. Epub 2021 Apr 13.

Centre of Restorative Dentistry Studies, Faculty of Dentistry, Universiti Teknologi MARA (UiTM), 47000, Sungai Buloh, Selangor, Malaysia. Electronic address:

Background: Gagging condition is among factors contributing to avoidance behavior to seek the dental treatment, and rigorous management is still under investigation. This study aims to explore the effect of listening to the self-preference music in reducing the gagging condition during dental impression procedure towards gagging patient. Physiology and psychological impact to the procedure with and without musical intervention are investigated. Read More

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Molecular and functional characterization of HtrA protein in Actinobacillus pleuropneumoniae.

Vet Microbiol 2021 Mar 26;257:109058. Epub 2021 Mar 26.

Research Center of Swine Disease, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China. Electronic address:

Actinobacillus pleuropneumoniae (A.pleuropneumoniae) causes serious economic loss for the swine industry. A high-temperature requirements A (HtrA)-like protease and its homologs have been reported to be involved in protein quality control and expression of important immunoprotective antigens in many pathogens. Read More

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Establishment of caprine airway epithelial cells grown in an air-liquid interface system to study caprine respiratory viruses and bacteria.

Vet Microbiol 2021 Apr 10;257:109067. Epub 2021 Apr 10.

Institute of Virology and Immunology (IVI), Bern, Switzerland; Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland.

Respiratory diseases negatively impact the global goat industry, but are understudied. There is a shortage of established and biological relevant in vitro or ex vivo assays to study caprine respiratory infections. Here, we describe the establishment of an in vitro system based on well-differentiated caprine airway epithelial cell (AEC) cultures grown under air liquid interface conditions as an experimental platform to study caprine respiratory pathogens. Read More

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Complications and outcomes following open laryngotracheal reconstruction: A 15 year experience at an Australian paediatric tertiary referral centre.

Int J Pediatr Otorhinolaryngol 2021 Mar 29;145:110687. Epub 2021 Mar 29.

Department of Paediatric Otolaryngology, The Children's Hospital at Westmead, The University of Sydney, Westmead, NSW, Australia; Discipline of Child and Adolescent Health, Faculty of Medicine and Health, University of Sydney, NSW, Australia. Electronic address:

Objective: To report on our experience with open pediatric laryngotracheal reconstruction (LTR) with cartilage interposition grafts over the past 15 years and document setbacks and factors that affect postoperative outcomes.

Method: A retrospective chart review was performed on all pediatric patients who underwent single and double-stage LTR at The Children's Hospital in Westmead between August 2004 and July 2019. The outcomes measured include the overall decannulation rate, rates of postoperative complications, need for subsequent procedures and postoperative functional results (dyspnea, stridor, voice impairment). Read More

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Multimodal brain predictors of current weight and weight gain in children enrolled in the ABCD study ®.

Dev Cogn Neurosci 2021 Mar 30;49:100948. Epub 2021 Mar 30.

Department of Psychiatry, University of Vermont, Burlington, VT, USA; Department of Psychological Science, University of Vermont, Burlington, VT, USA.

Multimodal neuroimaging assessments were utilized to identify generalizable brain correlates of current body mass index (BMI) and predictors of pathological weight gain (i.e., beyond normative development) one year later. Read More

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Functional analyses of chitinolytic enzymes in the formation of calcite prisms in Pinctada fucata.

Micron 2021 Apr 7;145:103063. Epub 2021 Apr 7.

Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, 113-8657, Japan. Electronic address:

The mollusk shells present distinctive microstructures that are formed by small amounts of organic matrices controlling the crystal growth of calcium carbonate. The shell of Pinctada fucata has the prismatic layer consisting of prisms of single calcite crystals and the nacreous layer consisting of aragonite tablets. The calcite crystal of prisms contains small angle grain boundaries caused by a dense intracrystalline organic matrix network to improve mechanical strength. Read More

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Gases emission during the continuous thermophilic composting of dairy manure amended with activated oil shale semicoke.

J Environ Manage 2021 Apr 13;290:112519. Epub 2021 Apr 13.

Shandong Industrial Engineering Laboratory of Biogas Production & Utilization, Key Laboratory of Biofuels, Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong Province, 266101, PR China; Dalian National Laboratory for Clean Energy, Dalian, 116023, PR China. Electronic address:

NH and greenhouse gases emission are big problems during composting, which can cause great nitrogen nutrient loss and environmental pollution. This study investigated effects of the porous bulking agent of oil shale semicoke and its activated material on the gases emission during the continuous thermophilic composting. Results showed addition of semicoke could significantly reduce the NH emission by 74. Read More

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Long-term epilepsy control, motor function, cognition, sleep and quality of life in children with West syndrome.

Epilepsy Res 2021 Apr 2;173:106629. Epub 2021 Apr 2.

Pediatric Neurology Unit, Department of Pediatrics, Postgraduate Institute of Medical Education & Research (PGIMER), Chandigarh, India. Electronic address:

Purpose: To assess epilepsy, motor function, cognitive, sleep, and quality of life outcomes and their predictors in a follow-up cohort with West syndrome (WS) at ≥5 years of age.

Methods: Cross-sectional evaluation in a follow-up cohort of WS (aged 5-14 years), between July 2018 and December 2019, was performed at a tertiary-care referral center in Northern India. 164 children were assessed in-person for epilepsy severity, functional status (gross motor and hand function), social quotient, behavioral comorbidities, sleep problems, and quality of life (QoL) using Early Childhood Epilepsy Severity Scale, Gross Motor Function Classification System, Manual Ability Classification System, Vineland Social Maturity Scale, Diagnostic and Statistical Manual of Mental disorders-5 criteria, Children's Sleep Habits Questionnaire, and PedsQL-Epilepsy module respectively. Read More

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Tortuosity Index Predicts Early Successful Reperfusion and Impacts Functional Status After Thrombectomy for Stroke.

World Neurosurg 2021 Apr 13. Epub 2021 Apr 13.

Neurosurgical Service, Beth Israel Deaconess Medical Center. Harvard Medical School, Boston, MA, United States. Electronic address:

Objectives: Literature is scarce in studies evaluating the anatomy of cervical vessels in stroke patients. We sought to investigate the effect of the vessels' tortuosity in procedural, angiographic and functional outcomes in patients with acute ischemic stroke (AIS) treated with mechanical thrombectomy (MT).

Materials And Methods: Patients with an emergent large vessel occlusion of the anterior circulation treated with MT between 2015 and 2020 were included. Read More

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