Acta Biomater 2017 06 29;55:163-171. Epub 2017 Mar 29.
Translational Tissue Engineering Center, Department of Biomedical Engineering and Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USA; Department of Urology and Department of Chemical & Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA. Electronic address:
Hyaluronic acid (HA) solutions effectively lubricate the ocular surface and are used for the relief of dry eye related symptoms. However, HA undergoes rapid clearance due to limited adhesion, which necessitates frequent instillation. Conversely, highly viscous artificial tear formulations with HA blur vision and interfere with blinking. Read More