Sci Rep 2021 05 4;11(1):9470. Epub 2021 May 4.
Department of Environmental Engineering, University of Seoul, 163, Seoulsiripdae-ro, Dongdaemun-gu, Seoul, 02504, Korea.
Phosphodiesterase-5 inhibitors (PDE-5i, such as Sildenafil, Tadalafil and Vardenafil, mainly prescribed to treat erectile dysfunction) and their generic drug equivalents have been widely marketed and consumed in Korea. From the concentrations detected in wastewater, we could deduce that relatively large amounts of PDE-5i were consumed without a legal prescription. Thus, PDE-5i's presence in the environment via sewage is unavoidable, and their environmental fate within a sewage treatment plant (STP) should be evaluated. Read More