27 results match your criteria fpg bun

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Evaluation of MASP1, CMPF and U.A serum levels in pre-diabetic subjects in comparison to Normal individuals for early diagnosis of subjects with pre-diabetes, a case-control study.

J Diabetes Metab Disord 2020 Dec 21;19(2):1593-1598. Epub 2020 Nov 21.

Department of Biochemistry, School of Medicine, Babol University of Medical Sciences, Babol, Iran.

Background: The present study designed to evaluate the Serum levels of CMPF, MASP1 and UA in pre-diabetic subjects was compared to normal subjects

Methods: This research is a case-control study. We studied 44 pre-diabetics with 44 normal subjects and were evaluated serum concentration of CMPF, Masp1 and U.Ain both groups andfurthermore serum concentration FPG, BUN, Cr, Cho, TG, HDLc, LDLc, AST, ALT, ALP, HbA1c was examined and correlation between of CMPF, Masp1 and U. Read More

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December 2020

Can probiotics supplementation improve glycemic & renal status in Diabetic Nephropathy? A systematic review and meta-analysis of clinical trials.

Endocr Metab Immune Disord Drug Targets 2021 Jan 21. Epub 2021 Jan 21.

Department of Clinical Nutrition, School of Nutrition & Food Science, Isfahan University of Medical Sciences, Isfahan. Iran.

Background & Aims: This meta-analysis was performed to quantify the effects of probiotics on renal and glycemic biomarkers among patients with Diabetic Nephropathy (DN).

Methods: Electronic databases were searched through May 10, 2020. All trials that investigated the effect of probiotics on serum glycemic markers (Fasting Plasma Glucose [FPG], Hemoglobin A1C, Insulin, Homeostatic Model AssessmentInsulin Resistance [HOMA-IR], and Quantitative Insulin Sensitivity Check Index [QUICKI]), and renal status markers (Creatinine [Cr], Blood Urea Nitrogen [BUN], and Glomerular Filtration Rate [GFR]) were included. Read More

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January 2021

Immunogenicity and Efficacy of Insulin Glargine Biosimilar Ezelin versus Originator Insulin Glargine in Patients with Type 2 Diabetes.

Diabetes Metab Syndr Obes 2021 12;14:107-116. Epub 2021 Jan 12.

Department of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.

Purpose: To compare the immunogenicity and efficacy of insulin glargine biosimilar Ezelin (EZL) versus originator insulin glargine Lantus (LAN) as a reference basal insulin in patients with type 2 diabetes (T2D).

Patients And Methods: This was a randomized, multicenter, open-label, 24-week study in insulin-naïve patients with T2D, with HbA1c of >7.0%. Read More

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January 2021

Clinical Characteristics of Diabetic Patients with COVID-19.

J Diabetes Res 2020 16;2020:1652403. Epub 2020 Jul 16.

Department of Gastroenterology, Wuhan Red Cross Hospital, Wuhan 430015, China.

Background: Since December 2019, novel coronavirus- (SARS-CoV-2) infected pneumonia (COVID-19) has rapidly spread throughout China. This study is aimed at describing the characteristics of COVID-19 patients in Wuhan.

Methods: 199 COVID-19 patients were admitted to Wuhan Red Cross Hospital in China from January 24th to March 15th. Read More

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September 2020

The effect of fenugreek seed supplementation on serum irisin levels, blood pressure, and liver and kidney function in patients with type 2 diabetes mellitus: A parallel randomized clinical trial.

Complement Ther Med 2020 Mar 1;49:102315. Epub 2020 Feb 1.

Student Research Committee, School of Health, Kerman University of Medical Sciences, Kerman, Iran; Nutrition Research Center, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address:

Objectives: This study was designed to determine the effects of fenugreek seed (FS) on serum irisin levels, blood pressure, and liver and kidney function in patients with type 2 diabetes mellitus (T2DM).

Methods: In an 8-week randomized controlled clinical trial, T2DM patients (n = 50) were assigned to the intervention (5 g FS powder, 3 times a day) or control group. Both groups received anti-diabetic drugs and nutritional consults. Read More

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[Renal Injury and Its Mechanisms in Mice].

Sichuan Da Xue Xue Bao Yi Xue Ban 2019 May;50(3):334-338

Department of Toxicology, School of Public Health, Xinxiang Medical University, Xinxiang 453003, China.

Objective: To study the mechanism of renal injury in mice with the leptin receptor homozygous deficiency.

Methods: Ten male of 28-week-old mice with leptin receptor heterozygous deficiency were selected as control group and ten male mice with leptin receptor homozygous deficiency were used in this study. After fasting for 8 hours, the body mass, fasting blood glucose (FBG) and glycosylated hemoglobulin (HbA1c) of the mice were measured. Read More

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Risk factors for the development of hyperuricemia: A STROBE-compliant cross-sectional and longitudinal study.

Medicine (Baltimore) 2019 Oct;98(42):e17597

Healthcare Center, Zhejiang University Hospital, Hangzhou, China.

Hyperuricemia has received increasing attention as a major public health problem. This study aims to investigate the risk factors for hyperuricemia and to explore the relationship between changes in biochemical variables and incident hyperuricemia.A cross-sectional and subsequently prospective study was performed among adults who took their health checkups at Zhejiang University Hospital. Read More

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October 2019

The effect of hydroalcoholic Saffron (Crocus sativus L.) extract on fasting plasma glucose, HbA1c, lipid profile, liver, and renal function tests in patients with type 2 diabetes mellitus: A randomized double-blind clinical trial.

Phytother Res 2019 Jun 3;33(6):1648-1657. Epub 2019 Apr 3.

Department of Epidemiology & Biostatistics, School of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Diabetes mellitus is a metabolic disease that manifested as hyperglycemia due to the defect in secretion or function of insulin. Studies have shown that saffron and its derivatives cause a significant reduction in plasma glucose levels in experimental models. The purpose of this study was to investigate the effect of the saffron extract on fasting plasma glucose (FPG), glycated hemoglobin level (HbA1c), lipid profile, liver enzymes, and renal function tests in type 2 diabetic patients. Read More

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[Warming needling combined with decoction for arteriosclerosis obliterans with stasis].

Zhongguo Zhen Jiu 2018 Aug;38(8):809-13

Department of TCM, 263 Clinical Branch, the Army General Hospital of the Chinese People's Liberation Army, Beijing 101100, China.

Objective: To observe the effect difference of warming needling combined with decoction and ciloprost for arteriosclerosis obliterans (ASO) with stasis.

Methods: A total of 96 ASO patients with stasis were randomly assigned into a combination group and a western medication group, 48 cases in each group. Anti-hypertension, glucose-lowering and lipid lowering therapies were applied in the two groups. Read More

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Protective effect of resveratrol on kidney in rats with diabetic nephropathy and its effect on endoplasmic reticulum stress.

Eur Rev Med Pharmacol Sci 2018 03;22(5):1485-1493

Department of Nephrology, Yantaishan Hospital, Yantai, Shandong Province, China.

Objective: Diabetic nephropathy (DN) can cause chronic renal insufficiency and significantly reduce the life quality of patients with diabetes mellitus, and may eventually lead to death. The study investigated the expression of endoplasmic reticulum stress-related factors, which have important roles in the progress of DN and to explore effects of resveratrol on DN and the possible mechanism.

Materials And Methods: Specific pathogen free (SPF) grade healthy male Sprague Dawley (SD) rats were divided into different groups for different treatments. Read More

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[Skin needle embedding for obese impaired glucose tolerance].

Zhongguo Zhen Jiu 2018 Jan;38(1):12-6

Department of TCM, Beijing Fengsheng Special Hospital of Traditional Medical Traumatology and Orthopaedics, Beijing 100033, China.

Objective: To explore the effect difference between the skin needle embedding therapy and western medication for obese impaired glucose tolerance (IGT).

Methods: A total of 300 cases of obese IGT were assigned into an embedding group and a western medication group by random number table, 150 cases in each one. Standardized diagnosis and treatment programs were applied to reduce blood pressure, lipid, weight, and exercise and scientific diet management were used. Read More

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January 2018

Acupuncture paired with herbal medicine for prediabetes: study protocol for a randomized controlled trial.

Trials 2017 06 28;18(1):297. Epub 2017 Jun 28.

The Fifth Affiliated Hospital of Guangzhou Medical University, The Fifth Clinical School of Guangzhou Medical University, Guangzhou, China.

Background: Type-2 diabetes has become a major disease and is known to seriously impair people's health worldwide. Prediabetes includes impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) and is the most critical period for preventing type-2 diabetes, as it can be identified and reversed. Studies in the past decade have indicated that acupuncture and Chinese herbal medicine may be beneficial for treating prediabetes. Read More

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Plasma level of miR-93 is associated with higher risk to develop type 2 diabetic retinopathy.

Graefes Arch Clin Exp Ophthalmol 2017 Jun 5;255(6):1159-1166. Epub 2017 Apr 5.

Department of Endocrinology and Metabolism, Suqian People's Hospital, Nanjing Drum Tower Hospital, No. 138, South Yellow River Road, Suqian, 223800, Jiangsu Province, People's Republic of China.

Purpose: MicroRNA-93 (miR-93) usually acts as a promoter of tumor progression in several human carcinomas. It has been found distinctly high in eyes with proliferative diabetic retinopathy (DR). The present study aims to investigate the role of plasma miR-93 in the progression of type 2 diabetic retinopathy (T2DR). Read More

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Plasma expression: an indicator for the severity of Type 2 diabetes with diabetic retinopathy.

Biosci Rep 2017 04 27;37(2). Epub 2017 Mar 27.

Department of Ophthalmology, China-Japan Union Hospital of Jilin University, Changchun 130033, P.R. China

To investigate the roles of plasma in the pathogenic process of Type 2 diabetes (T2D) with diabetic retinopathy (DR). T2D patients included patients without DR (NDR) group, patients with non-proliferative/background DR (BDR) group and patients with proliferative DR (PDR) group. Healthy individuals served as control group. Read More

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Association of blood neutrophil lymphocyte ratio in the patients with postmenopausal osteoporosis.

Pak J Med Sci 2016 May-Jun;32(3):762-5

Prof. Shaolin Li, Department of Radiation Medicine and Tumor, College of Basic Medicine, Chongqing Medical University, Yuzhong District, Chongqing, China.

Objective: To investigate the relationship between blood neutrophil lymphocyte ratio (NLR) and postmenopausal osteoporosis in Chinese women without diabetes.

Methods: Two hundred and thirty three postmenopausal women without diabetes were included in this study. The clinical data of patients including age, and body mass index (BMI) were recorded. Read More

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Study of the Correlation between the Level of CRP and Chemerin of Serum and the Occurrence and Development of DN.

Open Med (Wars) 2015 17;10(1):468-472. Epub 2015 Dec 17.

Henan University Huaihe Hospital, 475000, China.

The aim of the study was to find the correlation between CRP and chemerin in development of DN. We choose 90 type-2 diabetic patients between February 2010 and February 2013, who were then divided into DN group and healthy control group. The results of BP showed that there is no difference in SBP and DBP of patients in the three groups. Read More

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December 2015

Association of Serum Uric Acid with Body Mass Index: A Cross-Sectional Study from Jiangsu Province, China.

Iran J Public Health 2014 Nov;43(11):1503-9

2. Dept. of Medical Centerfor Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University , Nanjing, P.R. China.

Background: Body mass index (BMI) has been demonstrated to be associated with serum uric acid (SUA) level in many developed countries, however, there is still a lack of large sample study in Jiangsu Province, one of the most economically developed regions in China, where fat-rich diet is common.

Methods: Through retrospective analysis in healthy subjects, we determined the association of BMI with hyperuricemia risk. Data of 39,736 participants from January 2011 to June 2013 in China were analyzed for parameters including physical examinations and biochemical blood analysis. Read More

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November 2014

[Diabetic cardiomyopathy in medical examination patients with impaired glucose tolerance and Type 2 diabetes].

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2014 Jun;39(6):564-9

Health Management Center, Third Xiangya Hospital, Central South University, Changsha 410013,China.

Objective: To investigate the change of diabetic cardiomyopathy in patients with impaired glucose tolerance (IGT) and Type 2 diabetes (T2DM) and its influencing factors.

Methods: Patients with IGT and T2DM were divided into an IGT group (n=314), a T2DM group (n=368) and an NC group (400 normal subjects). The left ventricular ejection fractions (LVEF) and the interventricular septal depth (IVSd) were measured by Doppler echocardiography. Read More

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[Treatment of gouty arthritis in different phases by a series of tongfeng granule: an efficacy observation].

Zhongguo Zhong Xi Yi Jie He Za Zhi 2013 Dec;33(12):1603-7

Department of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China.

Objective: To evaluate the clinical efficacy of a series of Tongfeng Granule (TG) in treating gouty arthritis patients in different stages.

Methods: Ninety primary gout patients were randomly assigned to two groups, the TCM treatment group (60 cases) and the Western medicine control group (30 cases). Huzhang Tongfeng Granule in combination of external application of Jinhuang Ointment were given to those in the TCM treatment group in the acute phase, and Yinlian Tongfeng Granule in the remission phase. Read More

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December 2013

[Effects of quercetin on nuclear factor-κB p65 expression in renal ubiquitin-proteasome system of diabetic rats].

Zhonghua Nei Ke Za Zhi 2012 Jun;51(6):460-5

Department of Endocrinology, Fuzhou General Hospital of Nanjing Command, PLA, China.

Objective: To investigate the protective effect of quercetin on diabetic nephropathy and to explore its possible mechanism.

Methods: Type 2 diabetes mellitus rat model was established by feeding high-carbohydrate-fat diet and injecting with streptozotocin. At 72 hour after injection, blood samples were collected from the tail veins of all rats. Read More

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[Effects of two different extracts of total saponins from Cicer arietinum on kidney of T2DM rats].

Yao Xue Xue Bao 2012 Apr;47(4):541-5

Department of Pharmacology, Xinjiang Medical University, Urumqi 830011, China.

Protective effects of two different extracts of TSCA (total saponins from Cicer arietinum) were studied on kidney of T2DM rats. The diabetic model group was established with high calorie feeding and small dose injection of streptozotocin (STZ, 45 mg x kg(-1)). DM rats were randomly assigned to model group (feed with propylene glycol 1 mL/100 g), TSCA high dose group (300 mg x kg(-1)), TSCA low dose group (100 mg x kg(-1)) and normal control group (feed with propylene glycol 1 mL/100 g). Read More

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[Nephro-protective effects of total triterpenoids from Psidium guajava leaves on type 2 diabetic rats].

Zhong Yao Cai 2012 Jan;35(1):94-7

The Department of Pharmacology, Pharmacy College, Jinan University, Guangzhou 510632, China.

Objective: To investigate the nephro-protective effects of total triterpenoids from Psidium guajava leaves (TTPGL) on type 2 diabetic rats.

Methods: Diabetic rats were induced by intraperitoneal injection of streptozotocin (STZ, 35 mg/kg) and a high-fat diet. Diabetic rats were divided into five groups: diabetic model control, low-dose TTPGL-treated (60 mg/kg, L-TTPGL), medium-dose TTPGL-treated (120 mg/kg, M-TTPGL), high-dose TTPGL-treated (240 mg/kg, H-TTPGL) and rosiglitazone-treated (3 mg/kg, RSG). Read More

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January 2012

Fasting plasma glucose is an independent predictor for severity of H1N1 pneumonia.

BMC Infect Dis 2011 Apr 21;11:104. Epub 2011 Apr 21.

Department of Endocrinology, Second Hospital of Harbin Medical University, Harbin 150086, China.

Background: The pandemic influenza A (H1N1) virus emerged during 2009 and has spread worldwide. This virus can cause injuries to the lungs, liver, and heart. However, data regarding whether this influenza virus can affect pancreatic islets are limited. Read More

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Hypoglycemic effect of a leaf extract of Pseuderanthemum palatiferum (Nees) Radlk. in normal and streptozotocin-induced diabetic rats.

J Ethnopharmacol 2010 Nov 8;132(2):491-6. Epub 2010 Sep 8.

Department of Pharmaceutical Sciences, Faculty of Pharmacy, Mahasarakham University, Mahasarakham 44150, Thailand.

Ethnopharmacological Relevance: Pseuderanthemum palatiferum (Nees) Radlk (Acanthaceae) was first found in Northern Vietnam and expanded throughout the country including the Mekong Delta region. The leaves of this plant are recommended in folk medicine of Vietnam and Thailand for promoting and treating various diseases including hypertension, diarrhea, arthritis, hemorrhoids, stomachache, tumors, colitis, bleeding, wounds, constipation, flu, colon cancer, nephritis, and diabetes.

Aim Of The Study: The hypoglycemic effect of an 80% ethanolic leaf extract from the leaves of Pseuderanthemum palatiferum (PPE) was investigated in normal and streptozotocin (STZ)-induced diabetic rats. Read More

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November 2010

Levels of urinary matrix metalloproteinase-9 (MMP-9) and renal injuries in patients with type 2 diabetic nephropathy.

J Clin Lab Anal 2004 ;18(3):206-10

Department of Internal Medicine, Juntendo University School of Medicine, Tokyo, Japan.

To determine correlations among the levels of urinary MMP-9 and type-IV collagen, hyperglycemia, urinary protein excretion, and renal injuries in patients with type 2 diabetic nephropathy, we measured levels of urinary MMP-9 and protein, blood urea nitrogen (BUN), serum creatinine (s-Cr), fasting plasma glucose (FPG), and glycohemoglobin A1c (HbA1c) in 47 diabetic patients and 14 healthy adults. Urinary type-IV collagen was also measured in 28 diabetic patients and seven healthy adults. Patients with diabetic nephropathy were divided into two groups: 1). Read More

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November 2004

Urinary levels of monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8), and renal injuries in patients with type 2 diabetic nephropathy.

J Clin Lab Anal 2002 ;16(1):1-4

Division of Nephrology, Department of Internal Medicine, Juntendo University School of Medicine, Tokyo, Japan.

We examined the correlation among the levels of urinary monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8), hyperglycemia, and renal injuries in patients with type 2 diabetic nephropathy. The levels of urinary MCP-1, IL-8, protein excretion, blood urea nitrogen (BUN), serum creatinine (s-Cr), glycohemoglobin A1c (HbA1c), and fasting plasma glucose (FPG) were measured in 24 patients with type 2 diabetic nephropathy and 14 healthy adults as controls. Diabetic nephropathy was classified into three stages: stage 1 = normoalbuminuric, stage 2 = microalbuminuric, and stage 3 = macroalbuminuric. Read More

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[Studies on the reduction and correction risk factors for arteriosclerosis in junior high school pupils].

Nihon Koshu Eisei Zasshi 1993 Sep;40(9):881-92

Department of Public Health, School of Medicine, Dokkyo University.

Circulatory system examinations performed on first-grade pupils of junior high schools (12 years old; N = 1,204), identified 105 high-risk pupils with arteriosclerosis-promoting factors. These pupils were consulted on life-style modification, emphasizing nutrition and exercise, and encouraged to practice personal health management and self-monitoring. Reduction and correction of high risk factors were studied in these subjects, based on review of results of health examinations performed regularly up to the time of their graduation. Read More

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September 1993
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