380 results match your criteria forms iranian

Gene expression profiles of YAP1, TAZ, CRB3, and VDR in familial and sporadic multiple sclerosis among an Iranian population.

Sci Rep 2021 Apr 8;11(1):7713. Epub 2021 Apr 8.

Isfahan Neuroscience Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

Alterations in the regulatory mechanisms that control the process of myelination in the nervous system, may lead to the impaired myelination in the Multiple sclerosis. The Hippo pathway is an important mediator of myelination in the nervous system and might contribute to the pathophysiology of MS. This study examined via qPCR the RNA expression of YAP1, TAZ, and CRB3 as the key effectors of the Hippo pathway and also, VDR in the peripheral blood of 35 sporadic, 37 familial MS patients; and also 34 healthy first-degree relatives of the familial MS patients (HFR) and 40 healthy individuals without a family history of the disease (control). Read More

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The Effect of Teaching Formulaic Expressions Through Contrastive Lexical Approach on Iranian Pre-intermediate EFL Learners' Writing Skill.

J Psycholinguist Res 2021 Apr 8. Epub 2021 Apr 8.

Universiti Teknologi Malaysia, Johor Bahru, Malaysia.

This study aimed to investigate the effect of the contrastive lexical approach on Iranian EFL learners' writing skills. For this study, forty pre-intermediate students from a private English language institutes in Ahvaz, Iran were selected. Then, they were randomly divided into two equal groups of 20; one experimental and one control group. Read More

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Description of clinical features and genetic analysis of one ultra-rare (SPG64) and two common forms (SPG5A and SPG15) of hereditary spastic paraplegia families.

J Neurogenet 2021 Mar 26:1-11. Epub 2021 Mar 26.

Genetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.

Hereditary spastic paraplegia (HSP) is a clinically and genetically heterogeneous neurodegenerative disorder, characterized by lower-limb spasticity and weakness. To date, more than 82 loci/genes (SPG1-SPG82) have been identified that contribute to the cause of HSP. Despite the use of next-generation sequencing-based methods, genetic-analysis has failed in the finding of causative genes in more than 50% of HSP patients, indicating a more significant heterogeneity and absence of a given phenotype-genotype correlation. Read More

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Evaluation of Self-medication for Management of Odontogenic Pain in Iranian Patients.

Oral Health Prev Dent 2021 Jan;19(1):179-188

Purpose: Analgesics (painkillers) are one of the most widely used medications to reduce and control pain. The objective of this study was to investigate the self-medication with analgesics (narcotic or non-narcotic) in controlling odontogenic pain in patients visiting dental offices, dental clinics, and the dental school of Kerman.

Materials And Methods: This was a descriptive-analytic study, conducted in 2018. Read More

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January 2021

Stage-Specific Differential Gene Expression of Glutathione Peroxidase in and .

Rep Biochem Mol Biol 2020 Oct;9(3):324-330

Proteomics Research Center, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background: and are the etiological agents of cutaneous leishmaniosis. Leishmania species cause a board spectrum of phenotypes. A small number of genes are differentially expressed between them that have likely an important role in the disease phenotype. Read More

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October 2020

Stakeholders' perspectives of comprehensive sexuality education in Iranian male adolescences.

Reprod Health 2021 Feb 2;18(1):26. Epub 2021 Feb 2.

Student Research Committee, Faculty of Medicine, Semnan University of Medical Sciences, Semnan, Iran.

Background: A coherent sexuality education program for adolescents is part of their sexual and reproductive rights and can help them have a healthier future. Therefore, the aim of this study was to explore the perspectives and intervention preferences of Iranian stakeholders regarding comprehensive sexuality education (CSE) in male adolescents based on the IMB model (information, motivation, behavioral skills).

Methods: This study was a qualitative study that was analyzed through a directed content analysis approach. Read More

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February 2021

Association between ambient fine particulate matter with blood pressure levels among Iranian individuals admitted for cardiac and respiratory diseases: Data from CAPACITY study.

ARYA Atheroscler 2020 Jul;16(4):178-184

Professor, Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: The relation between air pollution and cardiovascular diseases (CVDs) risk factors, especially blood pressure (BP) levels, has been less frequently assessed. The aim of this study was evaluating the association between air pollutants of less than 2.5 µm [particulate matter (PM2. Read More

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Healthcare workers' sleep and mood disturbances during COVID-19 outbreak in an Iranian referral center.

Sleep Breath 2021 Feb 13. Epub 2021 Feb 13.

Université Laval, École de Psychologie, Pavillon F.A.S., Québec, Québec, G1K 7P4, Canada.

Purpose: This study aimed to assess the frequency of sleep and mood disturbances, and their association with COVID-like symptoms in healthcare workers (HCWs) with and without positive Coronavirus RT-PCR in a corona referral center.

Methods: This study was a cross-sectional, anonymous survey of adult HCWs. Data collection was performed in May and June 2020, while governmental restrictions were in place. Read More

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February 2021

A Nuclear Magnetic Resonance-Based Metabolomic Study to Identify Metabolite Differences between Iranian Isolates of major and .

Iran J Med Sci 2021 Jan;46(1):43-51

Proteomics Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background: Cutaneous leishmaniasis caused by species () is one of the most important parasitic diseases in humans. To gain information on the metabolite variations and biochemical pathways between , we used the comparative metabolome of metacyclic promastigotes in the Iranian isolates of and by proton nuclear magnetic resonance (H-NMR).

Methods: and were collected from three areas of Iran, namely Gonbad, Mashhad, and Bam, between 2017 and 2018, and were cultured. Read More

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January 2021

laying Farm: Up to Date Data on a Fowlpox Outbreak in Phylogenetic Analysis in Iran, 2018.

Arch Razi Inst 2021 01 1;75(4):501-508. Epub 2021 Jan 1.

Department of Microbiology and Immunology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.

Fowlpox is an economically significant viral disease in poultry, characterized by two forms of clinical signs, including cutaneous and diphtheritic lesions. This infection can have several adverse effects on flock performance, such as a reduction in egg production and growth and an increase in mortality. In winter 2018, an infection suspected to fowlpox was reported from a Hy-line W-36 laying farm in Isfahan province, Iran. Read More

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January 2021

National Guidelines for Cognitive Assessment and Rehabilitation of Iranian Traumatic Brain Injury Patients.

Arch Iran Med 2020 12 1;23(12):813-820. Epub 2020 Dec 1.

Department of Neurotrauma, Sina Trauma and Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Background: Individuals with moderate to severe traumatic brain injury (TBI) often have prolonged cognitive impairments, resulting in long-term problems with their real-life activities. Given the urgent need for evidence-based recommendations for neuropsychological management of Iranian TBI patients, the current work aimed to adapt eligible international guidelines for cognitive assessment and rehabilitation of the TBI patients in Iran.

Methods: The project was led by an executive committee, under the supervision of the Iranian Ministry of Health and Medical Education (MOHME). Read More

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December 2020

Older Iranian Muslim women's experiences of sex and sexuality: A biographical approach.

Br J Sociol 2020 Dec 20. Epub 2020 Dec 20.

Department of Social Sciences, University of Roehampton, London, UK.

Muslim women in Iran live in a patriarchal society which significantly restricts their freedom and agency. While there is a growing understanding of social change as it relates to younger Muslim women in Iran, the perspectives and experiences of older women are marginalized; mirroring problems with the intersections of age, gender, and sexuality in the West. In order to address this occlusion, this article draws on life history interviews with 30 older Muslim women living in Tehran and Karaj. Read More

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December 2020

Comprehensive Survey of Plagiarism in Iran.

Pak J Med Sci 2020 Nov-Dec;36(7):1441-1448

Ladan Rokni, PhD, Asia Contents Institute, Konkuk University, Seoul, South Korea.

Background And Objective: We conducted this study to assess the prevalence of plagiarism and to shed light on some dark aspects of this issue. The main objectives included to find out the etiology, prevalence, and detection of various forms plagiarism.

Methods: In this Cross-sectional study we used a questionnaire, face-to-face interview, analyzing the present notifications and codes, websites, and literature review. Read More

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November 2020

The advantages of clay mineral modification methods for enhancing adsorption efficiency in wastewater treatment: a review.

Environ Sci Pollut Res Int 2021 Jan 28;28(3):2572-2599. Epub 2020 Oct 28.

Department of Mineral Processing, Faculty of Mining Engineering, Sahand University of Technology, Tabriz, Iran.

This review discusses the recent trends in the research over the last 30 years to use clay minerals in natural and modified forms for removing different toxic organic/inorganic pollutants. The natural and modified forms of clay minerals have an exceptional ability to remove different contaminants. However, the modification methods can improve the clay mineral adsorption properties that consequently increase more adsorption sites and functional groups to adsorb different environmental pollutants. Read More

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January 2021

A new species and a new record of alpheid shrimps of the genus Salmoneus Holthuis, 1955 (Crustacea: Decapoda: Alpheidae) from Iran.

Zootaxa 2020 Aug 28;4838(4):zootaxa.4838.4.4. Epub 2020 Aug 28.

School of Biology and Centre of Excellence in Phylogeny of Living Organisms, College of Science, University of Tehran, Tehran, Iran Department of Biology and Ecology, and Institute of Environmental Technologies, Faculty of Science, University of Ostrava, Chittussiho 10, 71000 Ostrava, Czech Republic.

Extensive samplings of benthic fauna along the Iranian coastlines of the Persian Gulf and Gulf of Oman during 2018-2019 resulted in a small series of shrimps of the alpheid genus Salmoneus. Based on a thorough examination of this material, as well as previously collected specimens, one new species, S. rashedi n. Read More

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The identification of two pathogenic variants in a family with mild and severe forms of developmental delay.

J Hum Genet 2021 Apr 9;66(4):445-448. Epub 2020 Oct 9.

Department of Medical Genetics, Faculty of Medical Sciences, Tarbiat Modares University, P.O. Box, 14115-331, Tehran, Iran.

Intellectual disability (ID) accounts for 1% of the general population, and it is caused by the interplay between the genetic and/or environmental factors. The genetic components responsible for the development of ID are highly heterogeneous, and the phenotype and severity of the disease vary in patients even if they have an identical pathological variant and/or belong to the same family. Herein, we reported two male siblings with ID in an Iranian family. Read More

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A Hu sheep genome with the first ovine Y chromosome reveal introgression history after sheep domestication.

Sci China Life Sci 2020 Sep 24. Epub 2020 Sep 24.

Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, 712100, China.

The Y chromosome plays key roles in male fertility and reflects the evolutionary history of paternal lineages. Here, we present a de novo genome assembly of the Hu sheep with the first draft assembly of ovine Y chromosome (oMSY), using nanopore sequencing and Hi-C technologies. The oMSY that we generated spans 10. Read More

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September 2020

Identification of novel variants in Iranian consanguineous pedigrees with nonsyndromic hearing loss by next-generation sequencing.

J Clin Lab Anal 2020 Dec 30;34(12):e23544. Epub 2020 Aug 30.

Department of Medical Genetics, Faculty of Medical Sciences, Tarbiat Modares University, Teheran, Iran.

Background: The extremely high genetic heterogeneity of hearing loss due to diverse group of genes encoding proteins required for development, function, and maintenance of the complex auditory system makes the genetic diagnosis of this disease challenging. Up to now, 121 different genes have been identified for nonsyndromic hearing loss (NSHL), of which 76 genes are responsible for the most common forms of NSHL, autosomal recessive nonsyndromic hearing loss (ARNSHL).

Methods: After excluding mutations in the most common ARNSHL gene, GJB2, by Sanger sequencing, genetic screening for a panel of genes responsible for hereditary hearing impairment performed in 9 individuals with ARNSHL from unrelated Iranian consanguineous pedigrees. Read More

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December 2020

Clinicogenetical Variants of Progressive External Ophthalmoplegia - An Especial Review of Non-ophthalmic Manifestations.

Neurol India 2020 Jul-Aug;68(4):760-768

Department of Neurology, Zanjan University of Medical Sciences, Vali-e-Asr Hospital, Zanjan, Iran.

Progressive external ophthalmoplegia (PEO) is a slowly progressive myopathy characterized by extraocular muscles involvement, leading to frozen eyes without diplopia. The pattern of inheritance may be mitochondrial, autosomal dominant or, rarely, autosomal recessive. Sporadic forms were also reported. Read More

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Evaluation of the Effectiveness of One- and Multi-Session Exposure-Based Treatments in Reducing Biological and Psychological Responses to Rat Phobia Among Students.

Psychol Res Behav Manag 2020 12;13:665-679. Epub 2020 Aug 12.

Center of Basic Research in Infectious Diseases, Shiraz University of Medical Sciences, Shiraz, Iran.

Background: Animal phobia is one of the most common forms of specific phobias. This anxiety disorder challenges the medical student working with animal models. Regarding this, the present study was conducted to investigate the effectiveness of one- and multi-session cognitive exposure-based treatments in students with rat phobia. Read More

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Interventions promoting physical activity among adults and children in the six Gulf Cooperation Council countries: protocol for a systematic review.

BMJ Open 2020 08 20;10(8):e037122. Epub 2020 Aug 20.

Population Health Research Institute, St George's University of London, London, UK.

Introduction: Prevalence of overweight, obesity and diabetes are high and rising across the Gulf Cooperation Council (GCC) countries (Oman, Bahrain, Kuwait, Qatar, Saudi Arabia and the United Arab Emirates). In parallel, physical activity (PA) levels are low relative to international standards. PA aids weight control and reduces risk of non-communicable diseases including diabetes and cardiovascular disease. Read More

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Introducing nano/microencapsulated bioactive ingredients for extending the shelf-life of food products.

Adv Colloid Interface Sci 2020 Aug 12;282:102210. Epub 2020 Jul 12.

Faculty of Food Science and Technology, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, Iran. Electronic address:

The shelf-life of foods is affected by several aspects, mainly chemical and microbial events, resulting in a considerable decline in consumer's acceptance. There is an increasing interest to substitute synthetic preservatives with the plant-based bioactive ingredients which are safe and natural. However, full implementation of this replacement is postponed by some challenges associated with bioactive ingredients, including their low chemical stability, off-flavor, low solubility, and short-term effectiveness. Read More

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A homozygous stop gain mutation in BOD1 gene in a Lebanese patient with syndromic intellectual disability.

Clin Genet 2020 09;98(3):288-292

Medical Genetics Unit, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon.

Intellectual disability (ID) is a neurodevelopmental disorder characterized by limitations in both intellectual and behavioral functioning. It can occur in non-syndromic and syndromic forms involving multiple organs. While the majority of genetic variants linked to ID are de novo, inherited variants are also detected in some forms. Read More

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September 2020

CG/CA genotypes represent novel markers in the gene region associated with nephrotic syndrome.

J Genet 2020 ;99

Genetics Division, Faculty of Biological Sciences and Technologies, Department of Cellular and Molecular Biology and Microbiology, University of Isfahan, Isfahan, Iran.

Nephrotic syndrome (NS) is considered as a primary disease of the kidney that represents a heterogeneous group of glomerular disorders occurring mainly in children. It is generally divided into steroid-sensitive and steroid-resistant forms, depending upon the patient's response to steroid therapy. Among the genes involved, the gene has been reported as the causative gene in steroid resistant form of nephrotic syndrome. Read More

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February 2021

Quantitative proteomic analysis to determine differentially expressed proteins in axenic amastigotes of Leishmania tropica and Leishmania major.

IUBMB Life 2020 Aug 30;72(8):1715-1724. Epub 2020 Apr 30.

Department of Medical Parasitology and Mycology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Cutaneous leishmaniasis is commonly caused by Leishmania major and Leishmania tropica. In the present study, the differential expression of proteins was identified in the amastigote-like forms of L. tropica and L. Read More

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and hereditary spastic paraplegia: a novel variant in an Iranian family and overview of the genotype-phenotype correlation.

Int J Neurosci 2020 May 13:1-13. Epub 2020 May 13.

Genetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.

Purpose: SPG76 is one of the rare forms of hereditary spastic paraplegia (HSP) which causes by mutations in the gene. The mode of inheritance of SPG76 is autosomal recessive (AR) and so far, only 24 families and 25 mutations in this gene have been reported worldwide. These mutations have been associated with a spectrum of disorders from pure HSP to spastic ataxia. Read More

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Reporting a rare form of myopathy, myopathy with extrapyramidal signs, in an Iranian family using next generation sequencing: a case report.

BMC Med Genet 2020 04 15;21(1):77. Epub 2020 Apr 15.

Medical Genetics Lab, Kawsar Human Genetics Research Center, No. 41, Majlesi St., Valieasr Ave, Tehran, Iran.

Background: Myopathy with extrapyramidal signs (MPXPS) is an autosomal recessive mitochondrial disorder which is caused by mutation in mitochondrial calcium uptake 1 (MICU1) gene located on chromosome 10q22.1. Next Generation Sequencing (NGS) technology is the most effective method for identification of pathogenic variants with the ability to overcome some limitations which Sanger sequencing may encountered. Read More

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The Effect of Peer Support on Hope Among Patients Under Hemodialysis.

Int J Nephrol Renovasc Dis 2020 13;13:37-44. Epub 2020 Mar 13.

Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.

Introduction: Providing social support for patients under hemodialysis treatment can reduce their psychological, social, and physical problems. The present study aimed at determining the effect of peer support on hopefulness in patients under hemodialysis.

Methods: This clinical trial with a pre/posttest design was conducted on 128 patients who had referred to the hemodialysis centers of Shiraz University of Medical Sciences in 2019. Read More

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Comparison of gene expression of pyruvate kinase and tryparedoxin peroxidase in metacyclic promastigote forms of Leishmania (L.) tropica and L. major by real-time PCR

Ann Parasitol 2020 ;66(1):13-18

Proteomics Research Center, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Two predominant forms of cutaneous leishmaniosis are anthroponotic CL (ACL) and zoonotic CL (ZCL) caused by Leishmania (L.) tropica and L. major in Iran and many countries, respectively. Read More

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Molecular phylogeny and intraspecific differentiation of the species complex in Iran (Squamata: Agamidae) inferred from mitochondrial DNA sequences.

PeerJ 2020 17;8:e8295. Epub 2020 Feb 17.

Institute of Pharmacy and Molecular Biotechnology (IPMB), Heidelberg University, Heidelberg, Germany.

Background: consists of different morphotypes with restricted distributions in the Iranian Plateau. The phylogeny of the species complex has not been resolved so far, but recently were elevated from this complex into a full species. Other populations of the species complex need to be evaluated taxonomically. Read More

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February 2020