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Does the power of the laser devices matter for a successful HoLEP procedure? A prospective comparative study.

Int J Clin Pract 2021 Jun 15:e14531. Epub 2021 Jun 15.

Department of Urology, Biruni University School of Medicine, Istanbul, Turkey.

Background: The objectives of this prospective study were to evaluate the efficiency, safety and applicability of medium power (MP) holmium laser devices in the endoscopic enucleation of the enlarged prostate (HoLEP) compared to high power (HP) laser devices.

Methods: From October 2019 to July 2020, a total of 120 consecutive patients planned for HoLEP were divided randomly into two groups formed in terms of the power of the device used. While patients in Group 1 were treated with a MP device (50W) at 39. Read More

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Influence of Intracochlear Air on Experimental Pressure Measurements.

Audiol Neurootol 2021 Jun 15:1-6. Epub 2021 Jun 15.

Department of Otolaryngology, Head and Neck Surgery, Bielefeld University, Campus Mitte, Klinikum Bielefeld, Bielefeld, Germany.

Introduction: Intracochlear pressure changes have been assumed to play a central role in hearing preservation during cochlear implantation. The pressure in different settings has been evaluated (temporal bones vs. cochlea models) and was found to have advantages and disadvantages. Read More

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Hierarchical CoFe LDH/MOF nanorods array with strong coupling effect grown on carbon cloth enables efficient oxidation of water and urea.

Nanotechnology 2021 Jun 15. Epub 2021 Jun 15.

School of Environmental and Chemical Engineering, Shanghai University, Shangda Road 99, Shanghai, 200444, CHINA.

The construction of bifunctional non-noble electrocatalyst for oxygen evolution reaction (OER) and urea oxidation reaction (UOR) is urgent for overall water and urea splitting. Herein, a facile one-step chemical etching- reconstruction strategy is presented for fabricating one-dimensional hierarchical nanorods array composed of CoFe layered double hydroxide (LDH)/MOF supported on carbon cloth as OER and UOR catalysts. By precisely controlling the etching rate, the ligands from Co-MOFs are partially removed, and corresponding metal centers coordinates with hydroxyl ions to generate ultrathin amorphous CoFe LDH nanosheets. Read More

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Charge-transfer-induced 2D ferromagnetism and realization of thermo-remnant memory effect in ultrathin β-NiOOH-encapsulated graphene.

Nanotechnology 2021 Jun 15. Epub 2021 Jun 15.

Research Center for Spin Dynamics and Spin-Wave Devices, Seoul National University, Seoul 151-744, South Korea, Seoul, Korea (the Republic of).

For graphene-based 2D materials, charge transfer at the interface between graphene and ferromagnetic metal leads to many intriguing phenomena. However, because of the unidirectional spin orientation in ferromagnetic transition metals, interface interaction plays a detrimental role in diminishing the magnetic parameters on 2D surfaces. To overcome this issue, we have synthesized ultrathin 2D weak antiferromagnetic β-NiOOH layers on a graphene surface. Read More

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Antimicrobial use, biosecurity, herd characteristics, and antimicrobial resistance in indicator Escherichia coli in ten Finnish pig farms.

Prev Vet Med 2021 Jun 10;193:105408. Epub 2021 Jun 10.

Department of Production Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Finland.

We investigated connections between antimicrobial use (AMU), biosecurity, and the numbers of pigs and staff in ten Finnish farrow-to-finish herds. Data on AMU in each herd were collected for 12 months. AMU was quantified as treatment incidences per 1000 days at risk (TI) using the consensus defined daily dose calculation. Read More

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Effects of dynamic adsorption on bubble formation and coalescence in partitioned-EDGE devices.

J Colloid Interface Sci 2021 Jun 4;602:316-324. Epub 2021 Jun 4.

Wageningen University, Food Process Engineering Group, Bornse Weilanden 9, 6708 WG Wageningen, The Netherlands. Electronic address:

Hypothesis: Dynamic adsorption effects can play a crucial role in bubble formation and stabilization. We hypothesize that microfluidic tools provide direct insights to these effects, and that the final bubble size depends on the intersection of time scales for bubble formation versus adsorption of proteins.

Experiments: We use a microfluidic device to study Laplace pressure-driven formation of bubbles that are stabilized by whey proteins. Read More

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The role of carotenoids in proton-pumping rhodopsin as a primitive solar energy conversion system.

J Photochem Photobiol B 2021 Jun 9;221:112241. Epub 2021 Jun 9.

Dept. of Life Science and Institute of Biological Interfaces, Sogang University, Seoul 04107, Republic of Korea. Electronic address:

Rhodopsin and carotenoids are two molecules that certain bacteria use to absorb and utilize light. Type I rhodopsin, the simplest active proton transporter, converts light energy into an electrochemical potential. Light produces a proton gradient, which is known as the proton motive force across the cell membrane. Read More

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Interaction of nanoplastics with extracellular polymeric substances (EPS) in the aquatic environment: A special reference to eco-corona formation and associated impacts.

Water Res 2021 Jun 2;201:117319. Epub 2021 Jun 2.

Joint Laboratory of Guangdong Province and Hong Kong Region on Marine Bioresource Conservation and Exploitation, College of Marine Sciences, South China Agricultural University, Guangzhou 510641, China; Guangdong Laboratory for Lingnan Modern Agriculture, South China Agricultural University, Guangzhou 510642, China. Electronic address:

Nanoplastics (NPs) are plastic particles with sizes ranging between 1 and 1000 nm, exhibiting exceptional qualities such as large surface area, lightweight, durability; therefore, are widely used in cosmetics, paints, electronics, etc. NPs are inevitability released into the aquatic environment where they tend to interact with both, the extracellular polymeric substances (EPS) and other fractions of natural organic matter (NOM), respectively secreted by organisms (e.g. Read More

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Effect of chlorhexidine-loaded poly(amido amine) dendrimer on matrix metalloproteinase activities and remineralization in etched human dentin in vitro.

J Mech Behav Biomed Mater 2021 Jun 10;121:104625. Epub 2021 Jun 10.

Stomatological Hospital of Chongqing Medical University, Chongqing, 401147, China. Electronic address:

To investigate the effect of chlorhexidine (CHX)-loaded carboxyl-terminated poly (amido amine) dendrimer (CHX-PAMAM-COOH) on matrix metalloproteinase (MMP) activities and remineralization in human dentin, CHX-PAMAM-COOH was prepared and characterized by Fourier-transform infrared spectroscopy. The inhibitory effects of CHX, PAMAM-COOH, and CHX-PAMAM-COOH on soluble recombinant human matrix metalloproteinase (rhMMP-2) and dentin-bound endogenous MMP activity were measured using an MMP Activity Assay Kit. In situ zymography was performed to evaluate the gelatinase activity in dentin pretreated with CHX, PAMAM-COOH, and CHX-PAMAM-COOH. Read More

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A stochastic micro to macro mechanical model for the evolution of bone-implant interface stiffness.

Acta Biomater 2021 Jun 12. Epub 2021 Jun 12.

Department of Biomaterials, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden.

Upon placement of an implant into living bone, an interface is formed through which various biochemical, biological, physical and mechanical processes and interactions take place. This interface evolves over time as the mechanical properties of peri-implant bone increase. Owing to the multifactorial nature of interfacial processes, it is challenging to devise a comprehensive model for predicting the mechanical behavior of the bone-implant interface. Read More

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Microanatomical and secretory characterization of the salivary gland of the (Hemiptera, Reduviidae, Triatominae), a main vector of Chagas disease.

Open Biol 2021 Jun 16;11(6):210028. Epub 2021 Jun 16.

Instituto René Rachou, Fundação Oswaldo Cruz, Minas Gerais, Av. Augusto de Lima, 1715, CEP 30190-002, Belo Horizonte, MG, Brazil.

is the principal vector of , the aetiological agent of Chagas disease in American countries. This insect is haematophagous during all life cycles and, to antagonize its haemostatic, inflammatory and immune systems, it secretes saliva while feeding on the vertebrate host's blood. Here, we investigated characteristic changes of the salivary glands (SG) that occur during insect development. Read More

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Fracture risk during extraction of well-fixed extended cementless stems : porous versus hydroxyapatite coated.

Acta Orthop Belg 2021 Mar;87(1):41-45

The concern of extensive fracturing and bone damage during implant removal has been reported for ingrowing stems, in particular in extended porous coated stems, potentially impeding successful re- implantation of a femoral revision implant and consequently debilitating patients for life. The aim of the present study is to describe this particular complication and comparing the occurrence in porous coated and hydroxyapatite (HA) coated femoral implants. 62 consecutive revision hip replacements were per- formed between January 2010 and December 2016 at a single academic institution. Read More

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Using EEG to decode semantics during an artificial language learning task.

Brain Behav 2021 Jun 15. Epub 2021 Jun 15.

Departments of Computing Science and Psychology, University of Alberta, Edmonton, Canada.

Background: As we learn a new nonnative language (L2), we begin to build a new map of concepts onto orthographic representations. Eventually, L2 can conjure as rich a semantic representation as our native language (L1). However, the neural processes for mapping a new orthographic representation to a familiar meaning are not well understood or characterized. Read More

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Serial imaging of micro-agents and cancer cell spheroids in a microfluidic channel using multicolor fluorescence microscopy.

PLoS One 2021 15;16(6):e0253222. Epub 2021 Jun 15.

Surgical Robotics Laboratory, Department of Biomechanical Engineering, University of Twente, Enschede, The Netherlands.

Multicolor fluorescence microscopy is a powerful technique to fully visualize many biological phenomena by acquiring images from different spectrum channels. This study expands the scope of multicolor fluorescence microscopy by serial imaging of polystyrene micro-beads as surrogates for drug carriers, cancer spheroids formed using HeLa cells, and microfluidic channels. Three fluorophores with different spectral characteristics are utilized to perform multicolor microscopy. Read More

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Removal of triclosan from water by sepiolite supported bimetallic Fe/Ni nanoparticles.

Environ Technol 2021 Jun 15:1-10. Epub 2021 Jun 15.

Institute of Environmental pollution and health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai, People's Republic of China.

A simple and low-cost route to fabricate sepiolite-supported bimetallic Fe/Ni (Sep-Fe/Ni) nanoparticles was obtained by synchronous liquid phase reduction method. The as prepared composite was used to remove triclosan (TCS) from aqueous solutions. X-ray diffraction, scanning electron microscopy, transmission electron microscopy, and Brunauer-Emmett-Teller (BET) analysis were used for characterization of the materials. Read More

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Development of the Accessory Nidamental Gland and Associated Bacterial Community in the Hawaiian Bobtail Squid, .

Biol Bull 2021 Jun 22;240(3):205-218. Epub 2021 Apr 22.

AbstractThe Hawaiian bobtail squid, , has a female reproductive organ called the accessory nidamental gland that contains a symbiotic bacterial consortium. These bacteria are deposited from the accessory nidamental gland into the squid's egg cases, where the consortium prevents microbial fouling. The symbiont community is environmentally transmitted and conserved across host populations, yet little is known about how the organ develops and is colonized by bacteria. Read More

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First report of infecting white clover () in Finland.

Plant Dis 2021 Jun 15. Epub 2021 Jun 15.

Finnish Food Authority, Laboratory and Research, Mustialankatu 3, Helsinki, Finland, 00790;

Soybean dwarf virus (SbDV, genus ) is a single-stranded positive-sense RNA virus able to infect several legume species. SbDV was first reported in Japan where it was associated with significant yield losses in soybean (Tamada, 1969). Since then the virus has been detected worldwide. Read More

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Supramolecular Click Product Interactions Induce Dynamic Stiffening of Extracellular Matrix-Mimetic Hydrogels.

Biomacromolecules 2021 Jun 15. Epub 2021 Jun 15.

Department of Biomedical Engineering, Texas A&M University, College Station, Texas 77843-3120, United States.

Progressive stiffening of the extracellular matrix (ECM) is observed in tissue development as well as in pathologies such as cancer, cardiovascular disease, and fibrotic disease. However, methods to recapitulate this phenomenon face critical limitations. Here, we present a poly(ethylene glycol)-based peptide-functionalized ECM-mimetic hydrogel platform capable of facile, user-controlled dynamic stiffening. Read More

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Photoacid Generators Activated through Sequential Two-Photon Excitation: 1-Sulfonatoxy-2-alkoxyanthraquinone Derivatives.

J Phys Chem A 2021 Jun 15. Epub 2021 Jun 15.

Department of Chemistry and Biochemistry, University of Maryland, College Park, Maryland 20742, United States.

Two sulfonate ester derivatives of anthraquinone, 1-tosyloxy-2-methoxy-9,10-anthraquinone () and 1-trifluoromethylsulfonoxy-2-methoxy-9,10-anthraquinone (), were prepared and their ability to produce strong acids upon photoexcitation was examined. It is shown that these compounds generate acid with a yield that increases with light intensity when the applied photon dose is held constant. Additional experiments show that the rate of acid generation increases fourfold when visible light (532 nm) laser pulses are combined with ultraviolet (355 nm) compared with ultraviolet alone. Read More

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Synthesis of a Seco -Secologanin Aglycone Analogue of Interest toward Secoiridoids and Monoterpene Indole Alkaloids.

J Org Chem 2021 Jun 15. Epub 2021 Jun 15.

Institut de Chimie Moléculaire et des Matériaux d'Orsay (ICMMO), Université Paris-Saclay, CNRS, 91405 Orsay, France.

We report the access to an acyclic -secologanin aglycone analogue relevant to secoiridoids and monoterpene indole alkaloids. Its synthesis involved the regioselective allylic alkylation of a linear dienyl carbonate with dimethyl malonate, which was catalyzed by an iridium complex, and an anti-Markovnikov Wacker-type oxidation of the terminal alkene of the branched product that was obtained. The thus-formed aldehyde was engaged in a Pictet-Spengler reaction with tryptamine toward monoterpene indole alkaloids. Read More

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Dissecting the Flash Chemistry of Electrogenerated Reactive Intermediates by Microdroplet Fusion Mass Spectrometry.

Angew Chem Int Ed Engl 2021 Jun 15. Epub 2021 Jun 15.

Najing University, Chemistry, Xianlin Ave. 163, , 210023, Nanjing, CHINA.

A novel mass spectrometric method for probing the flash chemistry of electrogenerated reactive intermediates was developed based on rapid collision mixing of electrosprayed microdroplets by using a theta-glass capillary. The two individual microchannels of the theta-glass capillary are asymmetrically or symmetrically fabricated with a carbon bipolar electrode to produce intermediates in situ . Microdroplets containing the newly formed intermediates collide with those of the invoked reactants at sub-10 microsecond level, making it a powerful tool for exploring their ultrafast initial transformations. Read More

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Counterion Control of t-BuO-Mediated Single Electron Transfer to Nitrostilbenes Constructs N-Hydroxyindoles or Oxindoles.

Angew Chem Int Ed Engl 2021 Jun 15. Epub 2021 Jun 15.

University of Illinois at Chicago, Chemistry, 845 West Taylor Street, 60607, Chicago, UNITED STATES.

tert -Butoxide unlocks new reactivity patterns embedded in nitroarenes. Exposure of nitrostilbenes to sodium tert -butoxide was found to produce N -hydroxyindoles at room temperature without an additive. Changing the counterion to potassium changed the reaction outcome to yield solely oxindoles through an unprecedented dioxygen-transfer reaction followed by a 1,2-phenyl migration. Read More

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Elastic tissue disruption is a major pathogenic factor to human vascular disease.

Mol Biol Rep 2021 Jun 15. Epub 2021 Jun 15.

Nephrology Division, Internal Medicine Department, Hospital General Juan Cardona, c/ Pardo Bazán s/n, 15406, Ferrol, Spain.

Elastic fibers are essential components of the arterial extracellular matrix. They consist of the protein elastin and an array of microfibrils that support the protein and connect it to the surrounding matrix. The elastin gene encodes tropoelastin, a protein that requires extensive cross-linking to become elastin. Read More

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Atherogenic oxoaldehyde of cholesterol induces innate immune response in monocytes and macrophages.

Cell Biochem Biophys 2021 Jun 15. Epub 2021 Jun 15.

Departments of Environmental Toxicology, College of Sciences and Engineering, Southern University and A & M College, Baton Rouge, LA, 70813, USA.

Cholesterol oxidation product, 3β-hydroxy-5-oxo-5,6-secocholestan-6-al (cholesterol 5,6-secosterol, ChSeco or Atheronal-A), formed at inflammatory sites, has been shown to promote monocyte differentiation into macrophages and cause elevated expression of macrophage scavenger receptors. Since inflammation is a key event at all stages of atherosclerotic plaque formation, the pro-inflammatory actions of ChSeco in human THP-1 monocytes and mouse J774 macrophages were investigated in the present study by employing ELISA, qRT-PCR, and functional assays. An increase in the secretion of interleukin-8 and platelet-derived growth factor (PDGF) isoform AA and, to a limited extent, PDGF isoform BB was observed into the culture medium of THP-1 monocytes exposed to ChSeco. Read More

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Subcellular dynamics of estrogen-related receptors involved in transrepression through interactions with scaffold attachment factor B1.

Histochem Cell Biol 2021 Jun 15. Epub 2021 Jun 15.

Department of Anatomy and Neurobiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, 602-8566, Japan.

Estrogen-related receptor (ERR), a member of the nuclear receptor superfamily, consists of three subtypes (α, β, γ) and has strong homology with estrogen receptor. No endogenous ligands have been identified for ERRs, but they play key roles in metabolic, hormonal, and developmental processes as transcription factors without ligand binding. Although subnuclear dynamics are essential for nuclear events including nuclear receptor-mediated transcriptional regulation, the dynamics of ERRs are poorly understood. Read More

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Sexual selection and introgression in avian hybrid zones: Spotlight on Manacus.

Integr Comp Biol 2021 Jun 15. Epub 2021 Jun 15.

Behavior, Ecology, Evolution, and Systematics Program, University of Maryland, College Park, MD, USA.

Hybrid zones offer a window into the processes and outcomes of evolution, from species formation or fusion to genomic underpinnings of specific traits and isolating mechanisms. Sexual selection is believed to be an important factor in speciation processes, and hybrid zones present special opportunities to probe its impact. The manakins (Aves, Pipridae) are a promising group in which to study the interplay of sexual selection and natural hybridization: they show substantial variation across the family in the strength of sexual selection they experience, they readily hybridize within and between genera, and they appear to have formed hybrid species, a rare event in birds. Read More

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Development of an evaluation indicator system for the rational use of proton pump inhibitors in pediatric intensive care units: An application of Delphi method.

Medicine (Baltimore) 2021 Jun;100(24):e26327

Department of Pharmacy.

Abstract: Proton pump inhibitors are frequently used to prevent gastrointestinal bleeding in critically ill patients. But there is little information in the instructions about the usages for children. It is important to monitor the appropriate use of proton pump inhibitors, especially in pediatrics. Read More

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sp. nov. a novel actinobacterium isolated from the coral .

Int J Syst Evol Microbiol 2021 Jun;71(6)

Key Laboratory of Tropical Biological Resources of the Ministry of Education of China, Hainan University, Haikou 570228, PR China.

Strain HNM0947, representing a novel actinobacterium, was isolated from the coral collected from the coast of Wenchang, Hainan, China. The strain was found to have morphological and chemotaxonomic characteristics consistent with the genus . The organism formed abundant fragmented substrate mycelia and aerial mycelia which differentiated into non-motile, rod-shaped spores. Read More

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Glycosylation of a Nonfibrillizing Appendage Alters the Self-Assembly Pathway of a Synthetic β-Sheet Fibrillizing Peptide.

J Phys Chem B 2021 Jun 15. Epub 2021 Jun 15.

J. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, Florida 32611, United States.

Owing to their biocompatibility and biodegradability, short synthetic peptides that self-assemble into elongated β-sheet fibers (i.e., peptide nanofibers) are widely used to create biomaterials for diverse medical and biotechnology applications. Read More

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Tethered Silanoxyiodination of Alkenes.

J Org Chem 2021 Jun 15. Epub 2021 Jun 15.

Department of Medicinal Chemistry, University of Kansas, Lawrence, Kansas 66047, United States.

We present the first examples of tethered silanoxyiodination reactions of allylic alcohols. The products are useful silanediol organoiodide synthons and are formed with high regioselectivity and diastereocontrol. The reaction is scalable greater than 10-fold without loss of yield or selectivity. Read More

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