12,100 results match your criteria forensic autopsy


Unexpected death in a young child associated with anomalous aortic origin of the left main coronary artery without physical exertion: A case of an anomalous coronary artery with highly abundant elastic fibers.

Leg Med (Tokyo) 2021 Sep 15;53:101965. Epub 2021 Sep 15.

Tokyo Medical Examiner's Office, Tokyo Metropolitan Government, Tokyo, Japan.

Sudden death due to anomalous aortic origin of a coronary artery is far less common among young children in the absence of exercise stress. This report describes the case of a 2-year-old boy with a lower respiratory tract infection who suffered sudden cardiac arrest in his bed at home. The autopsy revealed that the left coronary artery (LCA) originated from the right sinus of Valsalva with an acute angle takeoff and traveled between the aorta and the pulmonary trunk (an interarterial course). Read More

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September 2021

Splenic peliosis associated with spontaneous rupture and massive bleeding.

Leg Med (Tokyo) 2021 Sep 15;53:101966. Epub 2021 Sep 15.

Department of Legal Medicine, International University of Health and Welfare, Japan.

We report findings from an autopsy case who died from massive bleeding because of splenic peliosis. The case subject was an 80-year-old man who had diabetes mellitus and who was receiving hemodialysis and anticoagulant therapy. Postmortem computed tomography demonstrated massive intra-abdominal hemorrhage especially seen around the spleen. Read More

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September 2021

Putrefaction in the pandemic: a comparative study of the frequency of advanced decomposition change in coronial autopsies since the start of the COVID-19 pandemic.

J Clin Pathol 2021 Sep 17. Epub 2021 Sep 17.

Cellular Pathology, Imperial College Healthcare NHS Trust, London, UK.

Aims: The aim of this study is to evaluate whether there has been a significant change in the frequency of markedly decomposed bodies having coronial autopsies since the UK's first COVID-19 lockdown.

Methods: We compared coronial autopsies (n=263) performed by one pathologist at a central London mortuary in the 1 year before and after 23 March 2020 by analysing their autopsy reports and coronial documentation.

Results: We have shown that there has been a significant increase of 70. Read More

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September 2021

Latent Medical Conditions of Drivers Involved in Road Traffic Collisions in Ghana: Implication from Autopsy Findings.

Clin Pathol 2021 Jan-Dec;14:2632010X211043871. Epub 2021 Sep 8.

Department of Pathology, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology, Ghana.

Background: Unlike some neighboring countries like Nigeria, few studies on actual causes, impact and the prevention of road traffic collisions have been carried out in Ghana. There is the need for further research and this study sought to link injuries that caused the death of drivers involved in vehicular collisions to the latent possible contributing diseases and medical conditions in these drivers and how these conditions predispose them to the collisions.

Methods: This is a retrospective study that used the forensic autopsy records of driver fatalities and various injuries and medical conditions of drivers involved in road traffic collisions. Read More

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September 2021

Spectrum of Renal Lesions on Autopsy: Experience of a Tertiary Level Institute Based on Retrospective Histopathological Analysis.

Cureus 2021 Aug 10;13(8):e17064. Epub 2021 Aug 10.

Pathology, Dr Baba Saheb Ambedkar (BSA) Medical College and Hospital, New Delhi, IND.

Introduction: Last few decades have seen a remarkable increase in the elderly population. Aging is an established risk factor for chronic kidney diseases associated with increased mortality and morbidity. The frequency and spectrum of renal pathology on autopsy specimen is not well documented and is often overlooked by physicians as well as forensic pathologists. Read More

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Phenibut, a GABAB Agonist, Detected in a Fatality.

J Anal Toxicol 2021 Sep 14. Epub 2021 Sep 14.

Harris County Institute of Forensic Sciences, 1861 Old Spanish Trail, Houston, TX 77054, USA.

Phenibut, a GABAB agonist structurally similar to baclofen, is not approved for medical use in the United States, but is available through internet suppliers for recreational use. Calls to poison control centers for phenibut have increased over the last five years, and there are many case reports of severe acute intoxications and withdrawals requiring hospitalization. This case report describes the autopsy and toxicology findings of a 26-year-old male found dead at home with phenibut containers on scene. Read More

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September 2021

A COVID-19-association-dependent categorization of death causes in 100 autopsy cases.

Geroscience 2021 Sep 11. Epub 2021 Sep 11.

Central Hospital of Southern Pest-National Institute of Hematology and Infectious Diseases, Budapest, Hungary.

From March through December 2020, 100 autopsies were performed (Semmelweis University, Budapest, Hungary), with chart review, of patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection demonstrated by real-time reverse-transcription polymerase chain reaction testing (mean age, 74.73 years, range 40-102 years; 50 males, mean age 71.96 years, and 50 females, mean age 77. Read More

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September 2021

Analysis of Pedestrian Fractures in Collisions Between Small Cars and Pedestrians Based on Surveillance Videos.

Am J Forensic Med Pathol 2021 Sep 10. Epub 2021 Sep 10.

From the School of Forensic Medicine Guangdong Provincial Research Center of Traffic Accident Identification Engineering Technology, Centre of Forensic Science Southern Medical University, School of Forensic Medicine, Southern Medical University School of Mechanical & Automotive Engineering, South China University of Technology, Guangzhou, Guangdong, China.

Objective: To discuss the collision relationship and the cause of the fracture caused by traffic accidents in which the front of a small car collides with the side of a pedestrian while braking.

Methods: The surveillance videos of 42 traffic accidents involving the front of a small car colliding with the side of a pedestrian while braking were collected. By analyzing the surveillance videos and the paths, the speed of the collision, the relationship between the vehicle and the pedestrian upon collision, and the movement trajectory of the human body were clearly identified. Read More

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September 2021

Ruptured Splenic Artery Pseudoaneurysm Causing Hemorrhage Into a Pancreatic Pseudocyst.

Am J Forensic Med Pathol 2021 Sep 10. Epub 2021 Sep 10.

From the Volusia County Medical Examiner's Office, Daytona Beach, FL University of South Carolina School of Medicine Departments of Radiology Pathology, Prisma Health, Greenville, SC.

Abstract: This case report describes fatal exsanguination due to splenic artery hemorrhage into a pancreatic pseudocyst with cystogastrostomy in a 46-year-old woman. The decedent had a complicated medical history including necrotizing pancreatitis, giant pseudocyst formation after cystogastrostomy procedure, and coiling of a hemorrhagic splenic artery. While hospitalized, she underwent embolization of a ruptured splenic artery pseudoaneurysm. Read More

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September 2021

Systemic AA Amyloidosis Associated With Intravenous Injection of Oral Prescription Opioids-An Autopsy Case Report.

Am J Forensic Med Pathol 2021 Sep 10. Epub 2021 Sep 10.

From the Department of Pathology Department of Medicine, University of California, San Diego, CA.

Abstract: There are reports of AA amyloidosis associated with intravenous and/or subcutaneous injection of street drugs, such as heroin and cocaine. Most reports describe patients with substance use disorder, renal amyloidosis and concurrent viral infections, such as hepatitis and/or human immunodeficiency virus. Herein, we present a case of systemic AA amyloidosis and sepsis in a 34-year-old woman with a history of intravenous injection of oral prescription medications (as evidenced by excipient lung disease) who had no known history of human immunodeficiency virus nor of hepatitis B or C. Read More

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September 2021

Fatal Excipients: An Autopsy Case Series of Excipient Lung Disease.

Am J Forensic Med Pathol 2021 Sep 10. Epub 2021 Sep 10.

From the Department of Pathology, NYU Langone Health, Long Island School of Medicine, Mineola, NY Miami-Dade County Medical Examiner Department, Miami, FL.

Abstract: Crushed oral tablets, when injected intravenously, may induce a foreign body granulomatous reaction in and around pulmonary arterioles, because of the presence of filler materials (excipients). This typically presents as shortness of breath in the context of pulmonary hypertension with arteriolar dilation and centrilobular nodules on imaging modalities. The constellation of findings may be overlooked or misdiagnosed by clinicians and pathologists, ultimately affecting patient care and postmortem assessment. Read More

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September 2021

When the Hijab causes death in workplace…: A case series.

Forensic Sci Int 2021 Aug 24;327:110965. Epub 2021 Aug 24.

Forensic Medicine Department, University Hospital Taher Sfar, Mahdia, Tunisia.

In eastern countries, Muslim females wear the Hijab, all the time, conforming to a moral standard of modesty and privacy. Worn in workplaces, the Hijab can causes accidents leading to death. In this context, we report three fatal work accidents related to the Hijab. Read More

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Medicolegal Evaluation of an Abandoned Dead Neonate: A Case Report.

JNMA J Nepal Med Assoc 2021 Mar 31;59(235):292-294. Epub 2021 Mar 31.

District Hospital, Palpa, Nepal.

The killing of an illegitimate newborn immediately or within 24 hours of birth is neonaticide which differs from other forms of homicide in terms of diagnosis and motives. Neonaticide is a cognizable offense where mothers are usually the perpetrators. This case reports the autopsy findings of a smothered neonate at a secluded location in rural Nepal. Read More

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Might life-threatening acute pulmonary edema occur after using recombinant tissue plasminogen activator? A case report.

BMC Neurol 2021 Sep 9;21(1):346. Epub 2021 Sep 9.

School of Forensic Medicine, Southern Medical University, 510515, Guangzhou, China.

Background: Recombinant tissue plasminogen activator (rt-pa) is the first-line drug for the treatment of acute ischemic stroke, and can lead to some complications.There were rare reports of death due to acute pulmonary edema during rt-pa thrombolysis treatment.

Case Presentation: This study reports a 30-year-old man was diagnosed with acute ischemic stroke and underwent rt-pa thrombolytic therapy. Read More

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September 2021

Sudden death in an adolescent due to undiagnosed classic Hodgkin lymphoma.

J Forensic Sci 2021 Sep 9. Epub 2021 Sep 9.

Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.

Few cases of natural sudden death presenting as an undiagnosed lymphoma have been reported in the literature, especially in adolescents. Herein we provide a report of sudden death caused by undiagnosed classic Hodgkin lymphoma (cHL). We describe an 18-year-old female who collapsed after several weeks of weight loss, decreased appetite, and dyspnea. Read More

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September 2021

Technical and interpretive pitfalls of postmortem CT: Five examples of errors revealed by autopsy.

J Forensic Sci 2021 Sep 7. Epub 2021 Sep 7.

Chiba University Center for Education and Research in Legal Medicine, Chiba, Japan.

Image acquisition of dead bodies, particularly using postmortem computed tomography (PMCT), has become common in forensic investigations worldwide. Meanwhile, in countries such as Japan which have an extremely low rate of autopsy, PMCT is being increasingly used in the clinical field to certify the cause of death (COD) without performing an autopsy or toxicological tests, even in cases of unnatural death. Additionally, these PMCT images are predominantly interpreted by clinical personnel such as emergency physicians or clinicians who are not trained in PMCT interpretation and who work for the police, that is, the so-called police doctors. Read More

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September 2021

The Relationship Between Medical School-Based Pathology Departments and Affiliated Forensic Pathology Training Sites.

Authors:
David N Bailey

Acad Pathol 2021 Jan-Dec;8:23742895211040208. Epub 2021 Aug 31.

Department of Pathology, University of California, San Diego, La Jolla, CA, USA.

Medical school-based pathology departments were surveyed in order to evaluate their relationship with sites providing forensic pathology training. Of 59 departments surveyed, 49 (83%) responded. Most (88%) respondents indicated that training occurs at an affiliated medical examiner/coroner office, and 78% indicated that the facility is 10 miles or less from the academic health center. Read More

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Evaluation of Pathological Findings of COVID-19 by Minimally Invasive Autopsies: A Single Tertiary Care Center Experience from India.

J Lab Physicians 2021 Jun 28;13(2):97-106. Epub 2021 Jun 28.

Department of Surgical Oncology, All India Institute of Medical Sciences (AIIMS), Jodhpur, Rajasthan, India.

 The 2019 novel coronavirus (2019-nCoV) has spread across the globe with more than 6 lakh deaths. Clinical autopsies are important to understand the pathobiology of the disease.  Autopsy techniques have been modified to be minimally invasive autopsies in all COVID-19 positive cases, and tissue biopsies were sampled from lungs, liver, and bone marrow within an hour after death. Read More

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3Tesla post-mortem MRI quantification of anatomical brain structures.

Forensic Sci Int 2021 Aug 27;327:110984. Epub 2021 Aug 27.

Institute of Forensic Medicine, University of Bern, Switzerland. Electronic address:

Quantitative post-mortem magnetic resonance imaging (PMMR) allows for measurement of T1 and T2 relaxation times and proton density (PD) of brain tissue. Quantitative PMMR values may be used for advanced post-mortem neuro-imaging diagnostics such as computer aided diagnosis. So far, the quantitative T1, T2 and PD post-mortem values of regular anatomical brain structures were unknown for a 3 Tesla PMMR application. Read More

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Piquerism in homicide: A knife wound analysis of a sexually motivated serial killer.

Authors:
Mark Pettigrew

J Forensic Sci 2021 Sep 4. Epub 2021 Sep 4.

Arden University, Coventry, UK.

As part of a wider research project into paraphilic disorders and homicide, a case is presented of a piquerist who achieved sexual satisfaction through the infliction of stabbing wounds. Against a background of sexual domination with willing and unwilling sexual partners, the offender stabbed four men to death. A study of the resulting autopsy reports, in association with the offender's testimony and crime scene documentation, was undertaken to discern a piquerist crime scene signature. Read More

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September 2021

Identifying gaps and improving investigation of fatal elder abuse and/or neglect.

J Forensic Sci 2021 Sep 3. Epub 2021 Sep 3.

Harris County Institute of Forensic Sciences, Houston, TX, USA.

Death investigator and autopsy reports for decedents 65 years and older within a major metropolitan area over a five-year period were assessed for the possibility of elder abuse and/or neglect. The study consisted of two stages. A simple two-question screening criteria was used to determine whether the decedent was (1) dependent on another for at least one activity of daily living and (2) had a presence of at least one indicator of abuse and/or neglect. Read More

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September 2021

Evaluation of the fire-related deaths: Autopsy study.

Ulus Travma Acil Cerrahi Derg 2021 Sep;27(5):539-546

Department of Forensic Medicine, Karadeniz Technical University Faculty of Medicine, Trabzon-Turkey.

Background: The fire is a public health problem that occurs because of various reasons, threatens the lives of organisms, and may cause economic losses. The forensic investigation and the crime (event) scene investigation and first medical examination to be performed for the persons in the fire scene might reveal important evidences.

Methods: The autopsy reports prepared in Trabzon Branch Office, The Ministry of Justice Council of Forensic Medicine, for the death cases found in fire scene between 2007 and 2016 were retrospectively examined. Read More

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September 2021

The role of PMCT for the assessment of the cause of death in natural disaster (landslide and flood): a Sicilian experience.

Int J Legal Med 2021 Sep 2. Epub 2021 Sep 2.

Section of Legal Medicine, Department of Health Promotion Sciences, Maternal and Infant Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Via del Vespro, 129, 90127, Palermo, Italy.

In this report, the authors provide a contribution of PMCT in assessing the cause of death due to natural disasters. Here, the PMCT findings of 43 subjects who died during both landslide and flood were described. The post-mortem imaging revealed, clearly, traumatic injuries and/or the presence of foreign material in airways allowing to assess the cause of death of each subject, together with external inspection and the collected circumstantial data. Read More

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September 2021

Novel Evaluation of Submandibular Salivary Gland Tissue for Use as an Alternative Postmortem Toxicology Specimen.

Am J Forensic Med Pathol 2021 Sep 2. Epub 2021 Sep 2.

From the Pathology Division, Toxicology Department, Western Michigan University Homer Stryker MD School of Medicine (WMed), Kalamazoo, MI.

Abstract: The collection of blood and tissue provides an opportunity for an objective comparison of autopsy results. Occasionally, a viable tissue sample is not available during autopsy. Expanding upon collected tissues to include a tissue that is accessible, is a possible drug depot, and is amendable to various analytical techniques may complement information obtained from other specimens. Read More

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September 2021

Case Report: Sudden cardiac death due to ventricular myocardial non-compaction.

F1000Res 2020 26;9:1045. Epub 2020 Aug 26.

Department of Forensic Medicine, Taher Sfar Hospital, University of Monastir, Mahdia, 5100, Tunisia.

Ventricular non-compaction (VNC) is a rare myocardium disorder, which can be both genetic and sporadic. A poor wall compaction process or an excessive trabeculae formation may be at the genesis of myocardial hypertrabeculation with multiple recesses. It is often complicated by ventricular dysfunction, arrhythmias and cardiac embolism. Read More

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September 2021

Wischnewski spots in a case of accidental hypothermia.

Clin Case Rep 2021 Aug 6;9(8). Epub 2021 May 6.

Attorney General's Department Forensic Science SA Government of South Australia Adelaide South Australia Australia.

Accidental hypothermia can be fatal, and is often associated with confusion and paradoxical undressing. Wischnewski spots are a classic manifestation of hypothermia at autopsy. Read More

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Factors associated with methamphetamine use in Japanese people who died of unnatural causes: Analysis using forensic autopsy reports.

Forensic Sci Int 2021 Aug 17;327:110946. Epub 2021 Aug 17.

Department of Forensic Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-Ku, Tokyo 113-0033, Japan; Department of Legal Medicine, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-Ku, Chiba, Chiba Prefecture 260-8670, Japan. Electronic address:

This study aimed to examine factors related to methamphetamine use in Japanese people who died of unnatural causes. This study used a cross-sectional design. A total of 3343 forensic autopsy reports were obtained from two forensic medicine departments in the Kanto region of Japan. Read More

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Cytokine storm and histopathological findings in 60 cases of COVID-19-related death: from viral load research to immunohistochemical quantification of major players IL-1β, IL-6, IL-15 and TNF-α.

Forensic Sci Med Pathol 2021 Aug 31. Epub 2021 Aug 31.

Department of Anatomical, Histological, Forensic and Orthopaedic Sciences (SAIMLAL), Sapienza University of Rome, Rome, Italy.

This study involves the histological analysis of samples taken during autopsies in cases of COVID-19 related death to evaluate the inflammatory cytokine response and the tissue localization of the virus in various organs. In all the selected cases, SARS-CoV-2 RT-PCR on swabs collected from the upper (nasopharynx and oropharynx) and/or the lower respiratory (trachea and primary bronchi) tracts were positive. Tissue localization of SARS-CoV-2 was detected using antibodies against the nucleoprotein and the spike protein. Read More

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