242,360 results match your criteria follow-up mortality

A morphovolumetric analysis of aneurysm sac evolution after elective endovascular abdominal aortic repair.

J Vasc Surg 2021 Apr 14. Epub 2021 Apr 14.

Objectives: Abdominal aortic aneurysm (AAA) sac shrinkage after endovascular repair (EVAR) has been regarded as positive marker of EVAR success durability. The purpose of this study was to describe the morphovolumetric changes of the AAA sac during follow-up after elective EVAR, and to analyze sac shrinkage related variables.

Methods: This is a single center, retrospective, observational cohort study from a tertiary referral university hospital. Read More

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Risk stratification of slide tracheoplasty for paediatric airway stenosis.

Ann Thorac Surg 2021 Apr 14. Epub 2021 Apr 14.

Great Ormond Street Hospital for Children, London, UK. Electronic address:

Background: Slide tracheoplasty (STP) is the procedure of choice for treatment of long segmental congenital tracheal stenosis (LSCTS). Few studies predict factors leading to re-intervention or mortality after STP. We analyzed our paediatric population to identify such factors and compared the outcome between two eras (1995-2012 and 2013-2017) METHODS: We analyzed 150 consecutive children who underwent STP from Feb 1995 to Dec 2017 in our hospital. Read More

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Frequency of bacteremia in patients with sickle cell disease: a longitudinal study.

Ann Hematol 2021 Apr 17. Epub 2021 Apr 17.

Specialty Pediatrics Division, Pediatric Gastroenterology, Johns Hopkins Aramco Healthcare, Dhahran, 31311, Saudi Arabia.

Bacterial infections in sickle cell disease (SCD) are associated with major risks of morbidity and mortality. Here, we describe the occurrence of bacteremia in SCD patients from 2000 to 2017. This is an observational study which included children and adults with SCD and fever and had confirmed positive blood cultures. Read More

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Prognostic Value of C-Reactive Protein to Albumin Ratio in Patients Resuscitated from Out-of-Hospital Cardiac Arrest.

Int J Clin Pract 2021 Apr 17:e14227. Epub 2021 Apr 17.

Department of Anesthesiology and Reanimation, University of Health Sciences, Mehmet Akif Inan Training and Research Hospital, Sanliurfa, Turkey.

Background: Despite major advances in basic and advanced life supports, patients who survived from out of hospital cardiac arrest (OHCA) has still poor prognosis. Several inflammatory parameters have been used to determine early and long-term prognosis in patients with OHCA. C-reactive protein-to-albumin ratio (CAR) is also a novel marker of systemic inflammation. Read More

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Autologous stem cell transplantation for post-transplant lymphoproliferative disorders after solid organ transplantation: a retrospective analysis from the Lymphoma Working Party of the EBMT.

Bone Marrow Transplant 2021 Apr 16. Epub 2021 Apr 16.

Lymphoma Working Party EBMT, Paris, France.

Published data describing the efficacy and safety of autologous stem-cell transplantation (autoSCT) in post-transplant lymphoproliferative disorders (PTLD) is limited to case reports. This is a retrospective analysis of 21 patients reported to the EBMT registry who received an autoSCT for PTLD post solid organ transplant (SOT). Median age at autoSCT was 47 (range: 22-71) years. Read More

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Sensitization during short-term mechanical circulatory support. Determinants, therapeutic management, and outcomes after heart transplant.

Rev Esp Cardiol (Engl Ed) 2021 Apr 13. Epub 2021 Apr 13.

Unidad de Insuficiencia Cardiaca Avanzada y Trasplante Cardiaco, Servicio de Cardiología, Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain.

Introduction And Objectives: The development of human-leukocyte antigen antibodies is a well-known adverse effect of the use of long-term ventricular assist devices (VADs). The aim of this study was to determine the incidence of sensitization during short-term mechanical circulatory support with VAD (CentriMag), its determinants, and its impact on posttransplant outcomes.

Methods: We performed a retrospective review of patients who were bridged to transplant with short-term VAD from 2009 to 2019. Read More

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Pulmonary Artery Proportional Pulse Pressure (PAPP) Index Identifies Patients With Improved Survival From the CardioMEMS Implantable Pulmonary Artery Pressure Monitor.

Heart Lung Circ 2021 Apr 13. Epub 2021 Apr 13.

University of Virginia Health System, Charlottesville, USA.

Background: Pulmonary artery proportional pulse pressure (PAPP) was recently shown to have prognostic value in heart failure (HF) with reduced ejection fraction (HFrEF) and pulmonary hypertension. We tested the hypothesis that PAPP would be predictive of adverse outcomes in patients with implantable pulmonary artery pressure monitor (CardioMEMS™ HF System, St. Jude Medical [now Abbott], Atlanta, GA, USA). Read More

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Survival and predictors of mortality among severe acute malnourished under-five children admitted at Felege-Hiwot comprehensive specialized hospital, northwest, Ethiopia: a retrospective cohort study.

BMC Pediatr 2021 Apr 16;21(1):176. Epub 2021 Apr 16.

Department of Pediatrics and Child Health Nursing, College of Health Sciences, Debre Tabor University, P.O.Box:272, Debre Tabor, Ethiopia.

Background: Malnutrition is still a global public health problem contributing for under-five morbidity and mortality. The case is similar in Ethiopia in which severe acute malnutrition is the major contributor to mortality being an underlying cause for nearly 45% of under-five deaths. However, there is no recent evidence that shows the time to death and public health importance of oxygen saturation and chest in drawing in the study area. Read More

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Flow-diverter stents in the early management of acutely ruptured brain aneurysms: effective rebleeding protection with low thromboembolic complications.

J Neurosurg 2021 Apr 16:1-8. Epub 2021 Apr 16.

4Neurology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel; and.

Objective: Flow-diverter stents (FDSs) are not generally used for the management of acutely ruptured aneurysms with associated subarachnoid hemorrhage (SAH). Herein, the authors present their experience with FDSs in this scenario, focusing on the antiplatelet regimen, perioperative management, and outcome.

Methods: The authors retrospectively reviewed their institutional database for the treatment and outcomes of all patients with acutely ruptured aneurysms and associated SAH from July 2010 to September 2018 who had received an FDS implant as stand-alone treatment within 4 days after diagnosis. Read More

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Validation of a host blood transcriptomic biomarker for pulmonary tuberculosis in people living with HIV: a prospective diagnostic and prognostic accuracy study.

Lancet Glob Health 2021 Apr 13. Epub 2021 Apr 13.

South African Tuberculosis Vaccine Initiative, Institute of Infectious Disease and Molecular Medicine, Division of Immunology, Department of Pathology, University of Cape Town, Cape Town, South Africa. Electronic address:

Background: A rapid, blood-based triage test that allows targeted investigation for tuberculosis at the point of care could shorten the time to tuberculosis treatment and reduce mortality. We aimed to test the performance of a host blood transcriptomic signature (RISK11) in diagnosing tuberculosis and predicting progression to active pulmonary disease (prognosis) in people with HIV in a community setting.

Methods: In this prospective diagnostic and prognostic accuracy study, adults (aged 18-59 years) with HIV were recruited from five communities in South Africa. Read More

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[Influenza A-associated acute necrotizing encephalopathy].

Rev Chil Pediatr 2020 Dec 24;91(6):941-946. Epub 2020 Sep 24.

Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.

Introduction: Acute necrotizing encephalopathy of childhood (ANEC) is a rare disease characterized by alteration of consciousness and multiple symmetric brain lesions mainly involving the thalamus. It presents a high mortality rate and severe sequelae.

Objective: To describe a school-age patient with influenza A-related ANEC with favorable evolution. Read More

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December 2020

Safety of image-guided radiotherapy in definitive radiotherapy for localized prostate cancer: a population-based analysis.

Br J Radiol 2021 Apr 16:20200456. Epub 2021 Apr 16.

Department of Radiation Oncology, China Medical University Hospital, Taichung, Taiwan.

Objectives: Image-guided radiotherapy (IGRT) is a recommended advanced radiation technique that is associated with fewer acute and chronic toxicities. However, one Phase III trial showed worse overall survival in the IGRT arm. The purpose of this observational study is to evaluate the impact of IGRT on overall survival. Read More

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Mobile Health Intervention Promoting Physical Activity in Adults Post Cardiac Rehabilitation: Pilot Randomized Controlled Trial.

JMIR Form Res 2021 Apr 16;5(4):e20468. Epub 2021 Apr 16.

Departments of Medicine and Epidemiology & Biostatistics, University of California San Francisco, San Francisco, CA, United States.

Background: Cardiac rehabilitation (CR) is an exercise-based program prescribed after cardiac events associated with improved physical, mental, and social functioning; however, many patients return to a sedentary lifestyle leading to deteriorating functional capacity after discharge from CR. Physical activity (PA) is critical to avoid recurrence of cardiac events and mortality and maintain functional capacity. Leveraging mobile health (mHealth) strategies to increase adherence to PA is a promising approach. Read More

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Body mass index and risk of all-cause mortality in normotensive and hypertensive adults: The Rural Chinese Cohort Study.

Public Health Nutr 2021 Apr 16:1-25. Epub 2021 Apr 16.

Study Team of Shenzhen's Sanming Project, The Affiliated Luohu Hospital of Shenzhen University Health Science Center, Shenzhen, Guangdong, People's Republic of China.

Objective: The impact of baseline hypertension status on the BMI-mortality association is still unclear. We aimed to examine the moderation effect of hypertension on the BMI-mortality association using a rural Chinese cohort.

Design: In this cohort study, we investigated the incident of mortality according to different BMI categories by hypertension status. Read More

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Bricker ileal conduit vs. Cutaneous ureterostomy after radical cystectomy for bladder cancer: a systematic review.

Int Braz J Urol 2021 Feb 20;47. Epub 2021 Feb 20.

Divisão de Urologia, Faculdade de Medicina do ABC, Santo André, SP, Brasil.

Purpose: A systematic review of the literature with available published literature to compare ileal conduit (IC) and cutaneous ureterostomy (CU) urinary diversions (UD) in terms of perioperative, functional, and oncological outcomes of high-risk elderly patients treated with radical cystectomy (RC). Protocol Registration: PROSPERO ID CRD42020168851.

Materials And Methods: A systematic review, according to the PRISMA Statement, was performed. Read More

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February 2021

Long-term pulmonary rehabilitation progressively reduces hospitalizations and mortality in a cohort of patients with severe and very severe copd: a 5-year follow up.

Eur J Phys Rehabil Med 2021 Apr 16. Epub 2021 Apr 16.

Internal Medicine, Institute of Thoracic Diseases School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

Backgroud: Pulmonary rehabilitation (PR) is recognized as a multidisciplinary intervention designed to reduce symptoms, improve functional status, and prevent acute exacerbations in patients with chronic obstructive pulmonary disease (COPD).

Aim: This study was aimed at evaluating the effects of a long-term PR program on the hospitalization rate and mortality of patients with severe and very severe COPD.

Materials And Methods: This was a prospective study where cohorts of 195 patients undergoing a PR program were followed up for 5 years. Read More

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Small Steatotic HCC: A Radiological Variant Associated With Improved Outcome After Ablation.

Hepatol Commun 2021 Apr 31;5(4):689-700. Epub 2020 Dec 31.

Department of Radiology St-Eloi University Hospital Montpellier France.

Percutaneous thermal ablation is a validated treatment option for small hepatocellular carcinoma (HCC). Steatotic HCC can be reliably detected by magnetic resonance imaging. To determine the clinical relevance of this radiological variant, we included 235 patients (cirrhosis in 92. Read More

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Cystatin C and interleukin-6 for prognosticating patients with acute decompensation of cirrhosis.

JGH Open 2021 Apr 9;5(4):459-464. Epub 2021 Mar 9.

Department of Gastroenterology G B Pant Institute of Postgraduate Medical Education and Research (GIPMER) New Delhi India.

Background And Aim: Systemic inflammation and organ dysfunction/failure can complicate acute decompensation (AD) of cirrhosis with progression to acute-on-chronic liver failure (ACLF), leading to increased mortality. There are few studies on serum biomarkers predicting renal dysfunction (RD) or ACLF in AD. Serum cystatin C (CysC) and interleukin-6 (IL-6) were evaluated for predicting RD, ACLF, and mortality in AD patients. Read More

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Development and Evaluation of Nomograms to Predict the Cancer-Specific Mortality and Overall Mortality of Patients with Hepatocellular Carcinoma.

Biomed Res Int 2021 29;2021:1658403. Epub 2021 Mar 29.

Department of Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.

Hepatocellular carcinoma (HCC) is the most common type among primary liver cancers (PLC). With its poor prognosis and survival rate, it is necessary for HCC patients to have a long-term follow-up. We believe that there are currently no relevant reports or literature about nomograms for predicting the cancer-specific mortality of HCC patients. Read More

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Long-Term Outcomes of Bronchopulmonary Dysplasia Under Two Different Diagnostic Criteria: A Retrospective Cohort Study at a Chinese Tertiary Center.

Front Pediatr 2021 30;9:648972. Epub 2021 Mar 30.

Department of Neonatology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Unlike other complications among very low birth weight infants (VLBW), the incidence of bronchopulmonary dysplasia (BPD) has not decreased substantially, partly because of the different definitions of BPD applied by different researchers. In this retrospective cohort study, we aimed to compare the 2018 revised definition and the 2001 consensus definition of BPD proposed by the National Institute of Child Health and Human Development (NICHD), as well as to identify which definition better predicts severe respiratory morbidities or death. We included 417 infants born at a gestational age <32 weeks and classified them as having BPD or without BPD based on the two definitions, with a final follow-up at 18-24 months. Read More

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Causes of Death After Colorectal Cancer Diagnosis: A Population-Based Study.

Front Oncol 2021 30;11:647179. Epub 2021 Mar 30.

Department of Medical Oncology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.

Non-cancer causes of death in patients with colorectal cancer (CRC) have not received much attention until now. The purpose of the current study is to investigate the non-cancer causes of death in patients with CRC at different periods of latency. Eligible patients with CRC were included from the Surveillance, Epidemiology, and End Results (SEER) database, and standardized mortality ratios (SMRs) were calculated using the SEER*Stat software 8. Read More

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A combination of surgery, theranostics, and liquid biopsy - a personalised oncologic approach to treatment of patients with advanced metastatic neuroendocrine neoplasms.

Int J Med Sci 2021 19;18(10):2166-2175. Epub 2021 Mar 19.

CURANOSTICUM Wiesbaden-Frankfurt at DKD Helios Klinik, Wiesbaden, Germany.

Neuroendocrine neoplasia (NEN) of small bowel (SBNEN) frequently present with metastatic disease. Theranostics (molecular imaging followed by targeting therapy) allow for personalised medicine. Liquid biopsies enable precise identification of residual disease and real-time monitoring of therapeutic response. Read More

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Effects of a Knowledge-Translation Intervention on Early Dialysis Initiation: A Cluster Randomized Trial.

J Am Soc Nephrol 2021 Apr 15. Epub 2021 Apr 15.

Department of Medicine and Community Health Sciences, Libin Cardiovascular Institute, Calgary, Canada.

Background: The Initiating Dialysis Early and Late (IDEAL) trial, published in 2009, found no clinically measurable benefit with respect to risk of mortality or early complications with early dialysis initiation versus deferred dialysis start. After these findings, guidelines recommended an intent-to-defer approach to dialysis initiation, with the goal of deferring it until clinical symptoms arise.

Methods: To evaluate a four-component knowledge translation intervention aimed at promoting an intent-to-defer strategy for dialysis initiation, we conducted a cluster randomized trial in Canada between October 2014 and November 2015. Read More

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Long-term mortality risk stratification of liver transplant recipients: real-time application of deep learning algorithms on longitudinal data.

Lancet Digit Health 2021 Apr 9. Epub 2021 Apr 9.

Department of Computer Science, University of Toronto, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada; Peter Munk Cardiac Centre, University Health Network, Toronto, ON, Canada; Vector Institute, Toronto, ON, Canada. Electronic address:

Background: Survival of liver transplant recipients beyond 1 year since transplantation is compromised by an increased risk of cancer, cardiovascular events, infection, and graft failure. Few clinical tools are available to identify patients at risk of these complications, which would flag them for screening tests and potentially life-saving interventions. In this retrospective analysis, we aimed to assess the ability of deep learning algorithms of longitudinal data from two prospective cohorts to predict complications resulting in death after liver transplantation over multiple timeframes, compared with logistic regression models. Read More

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Association between postoperative muscle wasting and survival in older patients undergoing surgery for non-metastatic colorectal cancer.

J Geriatr Oncol 2021 Apr 13. Epub 2021 Apr 13.

University of Groningen, University Medical Center Groningen, University Center for Geriatric Medicine, Groningen, the Netherlands.

Background: Preoperative sarcopenia in older patients is a risk factor for adverse outcomes after colorectal cancer (CRC) surgery. Longitudinal changes in muscle mass in this group have not been studied previously although muscle wasting may have prognostic significance regarding survival. We aimed to determine the association between muscle wasting and overall survival (OS) in older patients who underwent surgery for CRC. Read More

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Outcomes with drug-coated balloons vs. drug-eluting stents in small-vessel coronary artery disease.

Cardiovasc Revasc Med 2021 Mar 20. Epub 2021 Mar 20.

Minneapolis Heart Institute, Minneapolis, MN, USA. Electronic address:

Background: The use of drug-coated balloons (DCBs) in small-vessel coronary artery disease (SVD) remains controversial.

Methods: We performed a meta-analysis of all randomized controlled trials (RCTs) reporting the outcomes of DCB vs. DES in de-novo SVD. Read More

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Short and Mid Term Outcomes of Cryopreserved Abdominal Aortic Allografts Used as a Substitute for Infected Prosthetic Grafts in 200 Patients.

Eur J Vasc Endovasc Surg 2021 Apr 12. Epub 2021 Apr 12.

Sorbonne Université, Department of Vascular Surgery, Pitié-Salpêtrière Hospital, Assistance Publique Hôpitaux de Paris, France.

Objective: To investigate the use of cryopreserved arterial allografts (CAA) as a substitute for infected infrarenal aortic prostheses, and its outcomes.

Methods: A single centre retrospective study of consecutive patients receiving an abdominal aortic CAA after removal of an infected graft was conducted between January 1997 and December 2013. The primary outcome was the rate of allograft related revision surgery. Read More

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Prostate cancer outcomes disparities: Population survival analysis in an ethnically diverse nation.

Urol Oncol 2021 Apr 12. Epub 2021 Apr 12.

Department of Surgery, The University of Auckland, Auckland, New Zealand.

Background: Prostate cancer represents a significant health burden on New Zealand men. There are increasing concerns regarding inequities in prostate cancer morbidity and mortality among the different ethnic groups in New Zealand. This study aims to assess ethnic differences in survival outcomes among men newly diagnosed with prostate cancer. Read More

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Non-vitamin K antagonist oral anticoagulation versus left atrial appendage occlusion for primary and secondary stroke prevention after cardioembolic stroke.

Rev Port Cardiol 2021 Apr 12. Epub 2021 Apr 12.

Serviço de Neurologia, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal; Faculdade de Medicina, Universidade de Coimbra, Coimbra, Portugal.

Introduction: This study aimed to evaluate the performance of non-vitamin K antagonist oral anticoagulation (NOAC) in patients with previous stroke and non-valvular atrial fibrillation (AF) compared with left atrial appendage occlusion (LAAO) in primary and secondary stroke prevention settings.

Methods: This was a prospective, single-center, non-randomized cohort study of 302 consecutive patients with non-valvular AF and at high risk for stroke. Two treatment strategies were compared: LAAO (n=91) and long-term treatment with NOAC (n=149). Read More

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