11,013 results match your criteria flap survival

Predictors of Postoperative Complications After Paramedian Forehead Flaps.

Facial Plast Surg Aesthet Med 2021 Apr 13. Epub 2021 Apr 13.

Department of Otorhinolaryngology-Head and Neck Surgery, University of Maryland School of Medicine, Baltimore, Maryland, USA.

The predictors of postoperative complications after paramedian forehead flaps (PMFF) are unknown. To determine whether preoperative factors can predict post-PMFF complications. A retrospective review of 1438 adults from the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database who underwent PMFF between 2010 and 2018. Read More

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An 83-year-old-male with bronchopleural fistula and empyema successfully treated with multidisciplinary management of thoracostomy, endoscopic, and surgical treatment: a case report.

Ann Transl Med 2021 Mar;9(5):427

Division of Endocrinology and Metabolism, Department of Medicine, Zhejiang University Medical School Second Affiliated Hospital, Hangzhou, China.

Bronchopleural fistula (BPF) with empyema is a severe complication in patients undergoing lobectomy or pneumonectomy and is associated with high morbidity and mortality rates. Although a wide variety of treatment options exist, refractory cases with larger fistulas are still difficult to cure, especially in elderly patients. Here, we report a case of an 83-year-old man with stage I squamous cell lung carcinoma who underwent minimally invasive right lower lobectomy. Read More

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Curcumin promotes the survival of ischemic random skin flaps via autophagy.

Am J Transl Res 2021 15;13(3):1337-1351. Epub 2021 Mar 15.

Department of Burn and Wound Center, The First Affiliated Hospital of Wenzhou Medical University Wenzhou 325000, China.

Random skin flaps have been widely applied in reconstructive and plastic surgery; however, necrosis usually happens due to insufficient blood supply in the ischemic area of flaps. Curcumin (CUR) is a primary bioactive compound of turmeric (, L.), which has been proven to be effective on anticancer, decreasing oxidative stress and apoptosis through activating autophagy, and promoting angiogenesis in ischemic tissue. Read More

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Reconstruction of mutilating hand injuries by microsurgical free tissue transfers from the foot.

Injury 2021 Mar 30. Epub 2021 Mar 30.

Emot Hospital 1418 sok No14 Kahramanlar. İzmir, Turkey.

Introduction: The aim of this study is to present various hand reconstruction methods and provide technical notes regarding the treatment of mutilating hand injuries using free-tissue transfers from the foot and to investigate whether these transfers provide patients with a usable hand or not.

Patients And Methods: Ninety patients with mutilating hand injuries were included in the study. A total of 101 procedures were performed. Read More

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[Salvage laryngectomy after primary radio- and radiochemotherapy : A retrospective study. German version].

HNO 2021 Apr 9. Epub 2021 Apr 9.

Hals-Nasen-Ohrenklinik, Kopf- und Hals-Chirurgie, Universitätskliniken Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Waldstraße 1, 91054, Erlangen, Deutschland.

Background: Recurrent and residual laryngeal cancer after organ-preserving radio- or radiochemotherapy is associated with a poor prognosis. Salvage surgery is the most important therapeutic option in these cases.

Objective: The study assessed rates of recurrence and residual tumor as well as survival and complication rates after salvage laryngectomy at the authors' academic cancer center. Read More

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Safety and efficacy of secondary mandibular reconstruction using a free osteo-cutaneous fibula flap after segmental mandibular resection: a retrospective case-control study.

BMC Surg 2021 Apr 9;21(1):189. Epub 2021 Apr 9.

Division of Plastic and Reconstructive Surgery, Faculty of Medicine Shimane University, 89-1 Enya-cho, Izumo, Shimane, 693-8501, Japan.

Background: Free osteocutaneous fibula flap (FFF) is currently considered the best option for segmental mandibular reconstruction; however, there are only a few reports comparing secondary with primary reconstructions using FFF. This study aimed to evaluate the safety and efficacy of secondary mandibular reconstruction using FFF when compared with primary mandibular reconstruction.

Methods: From October 2018 to February 2020, patients who underwent mandibular reconstruction using FFF after segmental mandibulectomy were retrospectively reviewed. Read More

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Efficacy of Combined Electroporation-Mediated Gene Transfer of VEGF, HGF, and IL-10 on Skin Flap Survival, Monitored by Label-Free Optical Imaging: A Feasibility Study.

Front Surg 2021 23;8:639661. Epub 2021 Mar 23.

Department for BioMedical Research (DBMR), University of Bern, Bern, Switzerland.

Preventing surgical flaps necrosis remains challenging. Laser Doppler imaging and ultrasound can monitor blood flow in flap regions, but they do not directly measure the cellular response to ischemia. The study aimed to investigate the efficacy of synergistic electroporation-mediated gene transfer of interleukin 10 (IL-10) with either hepatocyte growth factor (HGF) or vascular endothelial growth factor (VEGF) on the survival of a modified McFarlane flap, and to evaluate the effect of the treatment on cell metabolism, using label-free fluorescence lifetime imaging. Read More

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Single Stage Reconstruction of Large Calvarial Exposure after Tumor Resection: A 3-Year Experience.

Wael H Mahmoud

World J Plast Surg 2021 Jan;10(1):30-36

Department of Plastic and Reconstructive Surgery, Faculty of Medicine, Tanta University, Tanta, Egypt.

Background: We aimed to review the treatment and outcome of patients' undergone reconstruction of large full thickness scalp defects with exposed calvarium after oncologic resection with the combined local flap and split-thickness skin graft (STSG) technique.

Methods: A retrospective review of 45 patients with scalp defects secondary to tumor extirpation was performed at the Plastic Surgery Department, Tanta University Hospital, Tanta, Egypt from Nov 2016 to Nov 2019. Patients, with large (>50 cm2) and full-thickness (exposed calvarium) scalp defects, who underwent scalp reconstruction with the combined local flap and STSG technique and had completed their medical records were enrolled. Read More

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January 2021

The Coverage of Soft-Tissue Defects Around the Foot and Ankle Using Free or Local Flaps: A Comparative Cohort Study.

Ann Plast Surg 2021 Mar 18. Epub 2021 Mar 18.

From the Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Key Laboratory of Orthopedics of Zhejiang Province, Wenzhou Department of Orthopedics, Ningbo Hangzhou Bay Hospital, Ningbo, Zhejiang, China Joseph M. Still Burn and Reconstructive Center, Jackson, MS.

Background: The purpose of this study was to compare the reconstructive outcomes of soft-tissue defects around foot and ankle with local or free flaps and attempt to provide an optimal strategy for these patients in comparison with the conventional guidelines.

Methods: A retrospective review of all continuous patients with foot and ankle reconstruction using different flaps from 2010 to 2018 was performed. Based on the flap types, the patients were divided into 2 groups: local flap group and free flap group. Read More

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Negative-pressure wound therapy combined with artificial dermis (Terudermis) followed by split-thickness skin graft might be an effective treatment option for wounds exposing tendon and bone: A retrospective observation study.

Medicine (Baltimore) 2021 Apr;100(14):e25395

Department of Surgery, Division of Plastic and Reconstructive Surgery.

Abstract: Skin grafts are not suitable for closing tendon- or bone-exposing wounds, which require flap surgery. Dermal regeneration templates have value for closing such wounds, but the disadvantages of the technique include implantation failures because of infection, hematoma formation, or inappropriate immobilization. Negative-pressure wound therapy was reported to increase graft acceptance in difficult wounds. Read More

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Aortic Intimo-intimal Intussusception: A Pooled Analysis of Published Reports.

Ann Vasc Surg 2021 Apr 5. Epub 2021 Apr 5.

Department of Vascular Surgery, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, P.R.China. Electronic address:

Aim: Aortic intimo-intimal intussusception (AoII) is a rare manifestation of aortic dissection with high mortality. This study aimed to obtain a comprehensive understanding of AoII.

Methods: Three databases (Pubmed, Scopus, Embase) were searched with predefined search terms ["intimal intussusception", "aortic intussusception", "(circumferential) AND (intimal dissection)" and "(circumferential) AND (aortic dissection)"]. Read More

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Long-term survival after head and neck cancer surgery with immediate free flap reconstruction.

Ann Chir Plast Esthet 2021 Apr 3. Epub 2021 Apr 3.

Department of Oncologic Surgery "Institut de Cancérologie de Lorraine", Nancy, France.

Background: Head and neck cancer is one of the most frequent cancers worldwide. A combination treatment including surgery is known to have a better survival rate than exclusive radiotherapy-chemotherapy. In extreme cases of non-metastatic patients who have voluminous tumor, or complex location, surgery with immediate reconstruction by free flap could be an option to improve long term survival. Read More

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Permanent Interstitial Cesium-131 Brachytherapy in Treating High-Risk Recurrent Head and Neck Cancer: A Prospective Pilot Study.

Front Oncol 2021 18;11:639480. Epub 2021 Mar 18.

Department of Radiation Oncology, University Hospitals Seidman Cancer Center, Case Western Reserve University, Cleveland, OH, United States.

Purpose/objectives: To establish the feasibility and safety of intraoperative placement of cesium-131 (Cs-131) seeds for re-irradiation in recurrent head and neck cancer (HNC).

Methods: Patients with resectable recurrent HNC who were deemed to have a high risk of second recurrence were eligible. Immediately after tumor extirpation, seeds were implanted in the surgical bed based on the preoperative treatment plan with intraoperative adjustment. Read More

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Free Gastric Flap for Oral Reconstruction-a Feasibility Study in Oral Defects.

Indian J Surg Oncol 2021 Mar 6;12(1):172-176. Epub 2021 Jan 6.

Department of Head And Neck Surgery Unit, Mahatma Gandhi Cancer Hospital, Miraj, India.

Background: Free flap transfer is a standard practice in reconstruction of oral defects. Fasciocutaneous flaps are commonly used for reconstruction of soft tissue defects. Replacement of oral mucosa with skin often causes discomfort, foreign body sensation, dysgeusia, problems with skin hair and morbidity at the donor site. Read More

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Evaluation of Role of Arterialization of Venous Flaps in Abdomen in Rats.

Indian J Plast Surg 2021 Jan 10;54(1):69-74. Epub 2021 Mar 10.

Department of Plastic Surgery, King George Medical College, Lucknow, Uttar Pradesh, India.

 Reconstruction forms the primary tenet in plastic surgery. Venous flaps are a known option but the survival is limited. Arterialization of venous flap can enhance its survival. Read More

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January 2021

Perioperative Risk Factors for One-Year Mortality in Patients With Free-Flap Reconstruction Due to Cancer of the Head and Neck.

J Oral Maxillofac Surg 2021 Mar 6. Epub 2021 Mar 6.

Professor and Head of Anesthesiology Department, University of Oulu, Medical Research Center, Research Group of Surgery, Anaesthesia and Intensive Care and Department of Anaesthesiology, Oulu University Hospital, Oulu, Finland. Electronic address:

Purpose: Head and neck cancer requiring free-flap reconstruction is associated with relatively high mortality. We aimed to evaluate perioperative risk factors for 1-year mortality in this patient group.

Methods: This is a single-center retrospective analysis of 204 patients operated during 2008 to 2018. Read More

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Hirudotherapy for neonatal limb ischemia during ECMO support: A word of caution.

J Card Surg 2021 Apr 3. Epub 2021 Apr 3.

Department of Pediatric Critical Care, University of Minnesota Masonic Children's Hospital, Minneapolis, Minnesota, USA.

Introduction: Disordered coagulation, clot formation and distal limb ischemia are complications of extracorporeal membrane oxygenation (ECMO) with significant morbidity and mortality. Medicinal leech therapy (hirudotherapy) has been attempted in plastic and orthopedic surgeries to improve venous congestion and salvage ischemic flaps. To our knowledge this has not been reported in pediatric cardiac surgery or during ECMO support. Read More

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Mucosal Melanoma of the Hard Palate: Surgical Treatment and Reconstruction.

Int J Environ Res Public Health 2021 Mar 24;18(7). Epub 2021 Mar 24.

School of Medicine, Vita-Salute San Raffaele University, 20100 Milano, Italy.

Mucosal melanomas of the head and neck region are uncommon pathologies that can affect the oral cavity, and are characterized by a high rate of mortality. Considering the lack of knowledge regarding risk and prognostic factors, current best clinical practice is represented by a large surgical excision with disease-free margins, eventually associated with a reconstructive flap. Indeed, given the frequent necessity of postoperative radiotherapy and fast healing process, a reconstruction of the surgical gap is advisable. Read More

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Impact of Goal Directed Therapy in Head and Neck Oncological Surgery with Microsurgical Reconstruction: Free Flap Viability and Complications.

Cancers (Basel) 2021 Mar 27;13(7). Epub 2021 Mar 27.

Anesthesia and Intensive Care Department, University Hospital La Paz, Universidad Autónoma de Madrid, 28046 Madrid, Spain.

(1) Background: Surgical outcomes in free flap reconstruction of head and neck defects in cancer patients have improved steadily in recent years; however, correct anaesthesia management is also important. The aim of this study has been to show whether goal directed therapy can improve flap viability and morbidity and mortality in surgical patients. (2) Methods: we performed an observational case control study to analyse the impact of introducing a semi invasive device (Flo Trac) during anaesthesia management to optimize fluid management. Read More

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Outcomes and Quality of Life Measures after Endoscopic Endonasal Resection of Kadish Stage C Olfactory Neuroblastomas.

World Neurosurg 2021 Mar 30. Epub 2021 Mar 30.

Department of Otolaryngology-Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China. Electronic address:

Objective: The Endoscopic Endonasal Approach (EEA) has been applied in the treatment of olfactory neuroblastoma (ONB). However, there is a lack of research examining the impact of EEA on locally advanced ONB. This study assessed the outcomes of EEA in patients with locally advanced ONB and its impact on the quality of life (QOL). Read More

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Columella reconstruction using double nasolabial flap and costal cartilage: A case report.

Ann Med Surg (Lond) 2021 Apr 13;64:102213. Epub 2021 Mar 13.

Department of Plastic Reconstructive and Aesthetic Surgery, Faculty of Medicine, Airlangga University, Surabaya, East Java, Indonesia.

Total loss of columella causes significant aesthetic and functional deformities due to its important functions which provides assistance and extension to the nose pointer. Noma is described as one of the developed sources of total columellar loss, and is also contagious, with the ability to intensely damage facial tissues and immediate structures. However, the condition is predominantly suffered in Africa, with an estimation of 20 instances per 100,000 individuals. Read More

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Positive Effect of Andrographolide Induced Autophagy on Random-Pattern Skin Flaps Survival.

Front Pharmacol 2021 16;12:653035. Epub 2021 Mar 16.

Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.

Random-pattern skin flap replantation is generally used in the reconstruction of surgical tissues and covering a series of skin flap defects. However, ischemia often occurs at the flap distal parts, which lead to flap necrosis. Previous studies have shown that andrographolide (Andro) protects against ischemic cardiovascular diseases, but little is known about the effect of Andro on flap viability. Read More

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Apigenin enhances viability of random skin flaps by activating autophagy.

Phytother Res 2021 Apr 1. Epub 2021 Apr 1.

Department of Orthopaedic Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.

Random skin flap is widely used in plastic surgery. However, flap necrosis caused by ischemia-reperfusion injury limits its clinical applications. Apigenin, a naturally occurring flavonoid mainly derived from plants, facilitates flap survival. Read More

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Free Tissue Transfer after Open Transmetatarsal Amputation in Diabetic Patients.

J Reconstr Microsurg 2021 Mar 31. Epub 2021 Mar 31.

Department of Plastic Surgery, Asan Medical Center, University of Ulsan, Seoul, Korea.

Background:  Transmetatarsal amputation (TMA) preserves functional gait while avoiding the need for prosthesis. However, when primary closure is not possible after amputation, higher level amputation is recommended. We hypothesize that reconstruction of the amputation stump using free tissue transfer when closure is not possible can achieve similar benefits as primarily closed TMAs. Read More

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Modus Operandi: Irrigation of the Modified Eloesser Flap in Heterogeneous Suppurative Lung Pathologies.

J Chest Surg 2021 Apr;54(2):137-142

Department of Anesthesia, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India.

Background: Refractory empyemas with collapsed lung and persistent bronchopleural fistulas pose significant problems to thoracic surgeons and impose a substantial burden in terms of morbidity and mortality. The modified Eloesser flap procedure is a useful palliative option for clearing infections. Herein, we present our experiences with the modified Eloesser flap procedure in mixed suppurative lung pathologies with a new technique of irrigation for persistent infection. Read More

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