2,525 results match your criteria fitness attention


Immune-mediated inflammatory diseases and nutrition: results from an online survey on patients' practices and perceptions.

BMC Nutr 2021 Jul 16;7(1):38. Epub 2021 Jul 16.

Carenity, Communauté de patients en ligne, Paris, France.

Background: The central role of microbiota and the contribution of diet in immune-mediated inflammatory diseases (IMID) are increasingly examined. However, patients' perspectives on nutrition and its impact on their disease has not received a lot of attention. We aimed to directly collect information from patients with IMID about their dietary behaviors and their perceptions of the influence of nutrition on their disease. Read More

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PyPEF-An Integrated Framework for Data-Driven Protein Engineering.

J Chem Inf Model 2021 Jul 14;61(7):3463-3476. Epub 2021 Jul 14.

Institute of Biotechnology, RWTH Aachen University, Worringer Weg 3, 52074 Aachen, Germany.

Data-driven strategies are gaining increased attention in protein engineering due to recent advances in access to large experimental databanks of proteins, next-generation sequencing (NGS), high-throughput screening (HTS) methods, and the development of artificial intelligence algorithms. However, the reliable prediction of beneficial amino acid substitutions, their combination, and the effect on functional properties remain the most significant challenges in protein engineering, which is applied to develop proteins and enzymes for biocatalysis, biomedicine, and life sciences. Here, we present a general-purpose framework (PyPEF: pythonic protein engineering framework) for performing data-driven protein engineering using machine learning methods combined with techniques from signal processing and statistical physics. Read More

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Development of QSAR models for evaluating pesticide toxicity against Skeletonema costatum.

Chemosphere 2021 Jul 6;285:131456. Epub 2021 Jul 6.

Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, 18 Shuangqing Road, Haidian District, Beijing, 100085, PR China.

Nowadays, the emergence of pesticides and its application in agriculture greatly improved the crop quality and food production. However, the resulted ecological problem caused by the widespread pesticide residues attracted more and more attention since the pesticides were harmful to most living organisms. Regulatory agencies such as Environmental Protection Agency (EPA) and European Chemicals Agency (ECHA) stipulated that a comprehensive pesticides risk assessment was essential and also underscored the application of computation method in evaluating pesticides. Read More

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Implementation of a Prevention Program Based on Adapted Physical Activity and Recommendations for Adolescents and Young Adults with Cancer: PREVAPAJA Study.

J Adolesc Young Adult Oncol 2021 Jul 13. Epub 2021 Jul 13.

Department Prevention, Cancer and Environment, Léon Bérard Cancer Center, Lyon, France.

In Europe, 20,000 Adolescent and Young Adults (AYAs) aged 15-25 years are diagnosed with cancer annually. Although prognosis is good, AYA cancer survivors are at greater risk of second primary cancers, cardiovascular disease, and various long-term effects. Benefits of physical activity (PA) in AYAs reported in current studies remain difficult to generalize; none has been performed in France. Read More

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Introduction to the Symposium: Effects of Light Pollution Across Diverse Natural Systems.

Integr Comp Biol 2021 Jul 12. Epub 2021 Jul 12.

Department of Biological Sciences, California Polytechnic State University, San Luis Obispo, CA 93407.

Light pollution, or the presence of artificial light at night (ALAN), is among the fastest growing but least understood anthropogenic stressor on the planet. While historically light pollution has not received attention comparable to climate change or chemical pollution, research over the past several decades has revealed the plethora of negative effects on humans, animals, and supporting ecosystems. As light pollution continues to grow in spatial, spectral, and temporal extent, we recognize the urgent need to understand how this affects circadian physiology, organismal fitness, life history traits and tradeoffs, population trends, and community interactions. Read More

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Tolerance to Glutaraldehyde in Mediated by Overexpression of the Aldehyde Reductase YqhD by YqhC.

Front Microbiol 2021 23;12:680553. Epub 2021 Jun 23.

Genome Center, University of California, Davis, Davis, CA, United States.

Glutaraldehyde is a widely used biocide on the market for about 50 years. Despite its broad application, several reports on the emergence of bacterial resistance, and occasional outbreaks caused by poorly disinfection, there is a gap of knowledge on the bacterial adaptation, tolerance, and resistance mechanisms to glutaraldehyde. Here, we analyze the effects of the independent selection of mutations in the transcriptional regulator for biological replicates of cells subjected to adaptive laboratory evolution (ALE) in the presence of glutaraldehyde. Read More

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Chemotherapy-induced toxicity in patients with testicular germ cell tumors: The impact of physical fitness and regular exercise.

Andrology 2021 Jul 10. Epub 2021 Jul 10.

Department of Metabolic Disease Research & Center of Physical Activity Research, Institute of Experimental Endocrinology, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia.

Background: Testicular germ cell tumors (TGCTs) represent ∼95% of testicular malignancies and are the most common type of malignancy in young male adults. While the incidence of TGCTs has increased during the last decades, the advances in treatment, namely introducing cisplatin into the chemotherapy regimen, have made TGCTs highly curable with the 10-year survival rate exceeding 95%. However, in parallel with increased cure rates, survivors may experience acute and late adverse effects of treatment, which increase morbidity, reduce the quality of life, and can be potentially life-threatening. Read More

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A thermodynamic model of protein structure evolution explains empirical amino acid substitution matrices.

Protein Sci 2021 Jul 4. Epub 2021 Jul 4.

Biochemistry Department, Brandeis University, Waltham, MA, USA.

Proteins evolve under a myriad of biophysical selection pressures that collectively control the patterns of amino acid substitutions. These evolutionary pressures are sufficiently consistent over time and across protein families to produce average substitution patterns, summarized in global amino acid substitution matrices such as BLOSUM, JTT, WAG, and LG, that can be used to successfully detect homologues, infer phylogenies, and reconstruct ancestral sequences. Although the factors which govern the variation of amino acid substitution rates have received much attention, the influence of thermodynamic stability constraints remains unresolved. Read More

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Association between Health-Related Physical Fitness and Respiratory Diseases in Adolescents: An Age- and Gender-Matched Study.

Int J Environ Res Public Health 2021 06 21;18(12). Epub 2021 Jun 21.

Department of Physical Education, Kyung Hee University (Global Campus), 1732 Deokyoungdaero, Giheung-gu, Yongin-si 17014, Gyeonggi-do, Korea.

The current study examined the differences in health-related physical fitness (HRPF), physical activity (PA), and sedentary behavior (SB) between adolescents with and without ongoing respiratory diseases (RD). This study's participants were from 12 to 15 years old (7th-10th grade) in South Korea. Adolescents with RD were selected through RD-related questions (i. Read More

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Increased Longevity and Dormancy of Soil-Buried Seeds from Advanced Crop-Wild Rice Hybrids Overexpressing the Transgene.

Biology (Basel) 2021 Jun 20;10(6). Epub 2021 Jun 20.

Ministry of Education Key Laboratory for Biodiversity and Ecological Engineering, School of Life Sciences, Fudan University, Songhu Road 2005, Shanghai 200438, China.

Estimating the fitness effect conferred by a transgene introgressed into populations of wild relative species from a genetically engineered (GE) crop plays an important role in assessing the potential environmental risks caused by transgene flow. Such estimation has essentially focused on the survival and fecundity-related characteristics measured above the ground, but with little attention to the fate of GE seeds shattered in the soil seed banks after maturation. To explore the survival and longevity of GE seeds in soil, we examined the germination behaviors of crop-wild hybrid seeds (F-F) from the lineages of a GE herbicide-tolerant rice () line that contains an endogenous transgene hybridized with two wild populations after the seeds were buried in soil. Read More

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Cannabinoid Modulation of Dopamine Release During Motivation, Periodic Reinforcement, Exploratory Behavior, Habit Formation, and Attention.

Front Synaptic Neurosci 2021 10;13:660218. Epub 2021 Jun 10.

Department of Biomedical Sciences, Marquette University, Milwaukee, WI, United States.

Motivational and attentional processes energize action sequences to facilitate evolutionary competition and promote behavioral fitness. Decades of neuropharmacology, electrophysiology and electrochemistry research indicate that the mesocorticolimbic DA pathway modulates both motivation and attention. More recently, it was realized that mesocorticolimbic DA function is tightly regulated by the brain's endocannabinoid system and greatly influenced by exogenous cannabinoids-which have been harnessed by humanity for medicinal, ritualistic, and recreational uses for 12,000 years. Read More

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Diagnosis and management of nasal obstruction in the athlete: a narrative review by subgroup 6 of the IOC Consensus Group on "Acute Respiratory Illness in the Athlete".

J Sports Med Phys Fitness 2021 Jun 22. Epub 2021 Jun 22.

Sport, Exercise Medicine and Lifestyle Institute (SEMLI), Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa -

Protection of the health of the athlete is required for high level sporting performance. Acute respiratory illness is the leading cause of illness and can compromise training and competition in athletes. To date the focus on respiratory health in athletes has largely been on acute upper respiratory infections and asthma / exercise induced bronchoconstriction (EIB), while nasal conditions have received less attention. Read More

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Extended phenotypes: buffers or amplifiers of climate change?

Trends Ecol Evol 2021 Jun 16. Epub 2021 Jun 16.

Department of Conservation Ecology and Entomology, Stellenbosch University, Stellenbosch, South Africa.

Historic approaches to understanding biological responses to climate change have viewed climate as something external that happens to organisms. Organisms, however, at least partially influence their own climate experience by moving within local mosaics of microclimates. Such behaviors are increasingly being incorporated into models of species distributions and climate sensitivity. Read More

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Physical activity referral scheme components: a study protocol for systematic review and meta-regression.

BMJ Open 2021 06 18;11(6):e049549. Epub 2021 Jun 18.

Department of Sport Science and Sport, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Bayern, Germany.

Introduction: In its attempt to establish effective physical activity promotion methods, research on physical activity referral schemes (PARS) is attracting significant attention. Sometimes known as physical activity on prescription schemes, PARS involve a well-defined procedure whereby a primary healthcare professional introduces a participant to the topic of physical activity and employs prescription or referral forms to connect the participant to physical activity opportunities, such as local fitness offers. The planned systematic review will focus on these referral routes and scheme components and how they are integrated into various PARS models worldwide. Read More

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Reliability and Validity of a 3-minute Psychomotor Vigilance Task (PVT) in Assessing Sensitivity to Sleep Loss and Alcohol: Fitness for Duty in Aviation and Transportation.

Sleep 2021 Jun 17. Epub 2021 Jun 17.

Department of Sleep and Human Factors Research, Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany.

Study Objectives: The psychomotor vigilance task (PVT) is a widely used objective method to measure sustained attention, but the standard 10-min version is often impractical in operational settings. We investigated the reliability and validity of a 3-min PVT administered on a portable handheld device assessing sensitivity to sleep loss and alcohol in relation to a 10-min PVT and to applied tasks.

Methods: Forty-seven healthy volunteers underwent a 12 consecutive days sleep lab protocol. Read More

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Fitness, fatness, body movement, and diet in adolescents: clustering and associations with elevated blood pressure.

J Sports Med Phys Fitness 2021 Jun 16. Epub 2021 Jun 16.

Research Group in Physical Activity, Sports and Health Sciences (GICAFS), Departamento de Cultura Física, Universidad de Córdoba, Montería, Colombia.

Background: The study of clusters of risk factors for elevated blood pressure (EBP) among adolescents from low- middle-income countries has received little research attention. The objective of the study was to identify clusters of EBP precursors (i.e. Read More

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Psychosocial Aspects of Participation in Competitive Sports Among Older Athletes: A Scoping Review.

Gerontologist 2021 Jun 15. Epub 2021 Jun 15.

Department of Social Sciences, Glasgow Caledonian University, Glasgow, United Kingdom.

Background And Objectives: In the last decade, sport has been considered a tool in active aging to maintain physical fitness, improve mental wellbeing and form social relationships among older people. However, a thorough psychosocial understanding of the phenomenon of older athletes competing in sports events is lacking. Most research has focused on competitive sports participation in the young population. Read More

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Brain Exercising Games With Consumer-Grade Single-Channel Electroencephalogram Neurofeedback: Pre-Post Intervention Study.

JMIR Serious Games 2021 Jun 15;9(2):e26872. Epub 2021 Jun 15.

Department of Computer Engineering, Faculty of Engineering, Chulalongkorn University, Bangkok, Thailand.

Background: The aging population is one of the major challenges affecting societies worldwide. As the proportion of older people grows dramatically, so does the number of age-related illnesses such as dementia-related illnesses. Preventive care should be emphasized as an effective tool to combat and manage this situation. Read More

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Follow the leader? Orange-fronted conures eavesdrop on conspecific vocal performance and utilise it in social decisions.

PLoS One 2021 9;16(6):e0252374. Epub 2021 Jun 9.

Department of Biology, University of Copenhagen, Copenhagen, Denmark.

Animals regularly use social information to make fitness-relevant decisions. Particularly in social interactions, social information can reduce uncertainty about the relative quality of conspecifics, thus optimising decisions on with whom and how to interact. One important resource for individuals living in social environments is the production of information by signalling conspecifics. Read More

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An investigation of sickle cell trait, body mass index, and fitness in relation to venous thromboembolism among African American adults.

J Thromb Haemost 2021 Jun 9. Epub 2021 Jun 9.

Department of Medicine, Division of Primary Care and Population Health, Stanford University School of Medicine, Stanford, California, USA.

Background: The relationships of sickle cell trait (SCT), body mass index (BMI), and physical fitness to venous thromboembolism (VTE) in young adults have received little attention.

Objectives: To test for associations among SCT, BMI, fitness, and VTE.

Patients/methods: We conducted a retrospective cohort study of 48,316 SCT-tested, African American individuals in the US Army during 2011-14. Read More

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Bone parameters of elite athletes with oligomenorrhea and prevalence seeking medical attention: a cross-sectional study.

J Bone Miner Metab 2021 Jun 8. Epub 2021 Jun 8.

Faculty of Sport Sciences, Waseda University, 2-579-15 Mikajima, Tokorozawa, Saitama, 359-1192, Japan.

Introduction: Since the definition of secondary amenorrhea is cessation of regular menses for more than 3 months, it is likely that athletes with irregular menstrual cycles, including oligomenorrhea, do not consider the condition as serious. However, the consequences of untreated oligomenorrhea have not been investigated in elite track and field athletes.

Materials And Methods: The cohort consisted of 91 elite-level track and field athletes. Read More

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Mitochondrial structural alterations in ovarian cancer patient-derived xenografts resistant to cisplatin.

Am J Cancer Res 2021 15;11(5):2303-2311. Epub 2021 May 15.

Laboratory of Molecular Pharmacology, Istituto di Ricerche Farmacologiche Mario Negri-IRCCS Via Mario Negri 2, Milan 20156, Italy.

Mitochondria have attracted attention in cancer research as organelles associated with tumor development and response to therapy. We recently reported acquisition of resistance to cisplatin (DDP) associated with a metabolic rewiring in ovarian cancer patient-derived xenografts (PDXs) models. DDP-resistant PDXs models were obtained mimicking the clinical setting, treating mice bearing sensitive-DDP tumors with multiple cycles of DDP until the development of resistance. Read More

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Internet of things-based energy-efficient optimized heuristic framework to monitor sportsperson's health.

Technol Health Care 2021 May 26. Epub 2021 May 26.

Department of Computer Science and Engineering, Saveetha School of Engineering, Simats, India.

Background: Recently, wearable technologies have gained attention in diverse applications of the medical platform to guarantee the health and safety of the sportsperson with the assistance of the Internet of things (IoT) device. The IoT device's topology varies due to the shift in users' orientation and accessibility, making it impossible to assign resources, and routing strategies have been considered the prominent factor in the current medical research. Further, for sportspersons with sudden cardiac arrests, hospital survival rates are low in which wearable IoT devices play a significant role. Read More

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Mobile and Wearable Technology for the Monitoring of Diabetes-Related Parameters: Systematic Review.

JMIR Mhealth Uhealth 2021 06 3;9(6):e25138. Epub 2021 Jun 3.

Research Center for Information and Communication Technologies, University of Granada, Granada, Spain.

Background: Diabetes mellitus is a metabolic disorder that affects hundreds of millions of people worldwide and causes several million deaths every year. Such a dramatic scenario puts some pressure on administrations, care services, and the scientific community to seek novel solutions that may help control and deal effectively with this condition and its consequences.

Objective: This study aims to review the literature on the use of modern mobile and wearable technology for monitoring parameters that condition the development or evolution of diabetes mellitus. Read More

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The microbiome-shaping roles of bacteriocins.

Nat Rev Microbiol 2021 Jun 1. Epub 2021 Jun 1.

Interfaculty Institute of Microbiology and Infection Medicine, Department of Infection Biology, University of Tübingen, Tübingen, Germany.

The microbiomes on human body surfaces affect health in multiple ways. They include not only commensal or mutualistic bacteria but also potentially pathogenic bacteria, which can enter sterile tissues to cause invasive infection. Many commensal bacteria produce small antibacterial molecules termed bacteriocins that have the capacity to eliminate specific colonizing pathogens; as such, bacteriocins have attracted increased attention as potential microbiome-editing tools. Read More

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Association between Creativity and Memory with Cardiorespiratory Fitness and Lifestyle among Chilean Schoolchildren.

Nutrients 2021 May 25;13(6). Epub 2021 May 25.

Department of Physical Education, Sport and Recreation, Universidad de La Frontera, Temuco 478000, Chile.

The objective was to investigate the association between creativity and memory with cardiorespiratory fitness (CRF; i.e., CFR classification and V˙O); lifestyle parameters (i. Read More

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Literature Review of the Implications of Exercise Rehabilitation Strategies for SARS Patients on the Recovery of COVID-19 Patients.

Healthcare (Basel) 2021 May 18;9(5). Epub 2021 May 18.

Department of Physical Education, Hunan University, Changsha 410000, China.

As a global pandemic, COVID-19 shows no sign of letting up. With the control of the epidemic in China, the proportion of patients with severe and critical diseases being cured and discharged from hospital has increased, and the recovery of COVID-19 patients has become an important issue that urgently needs attention and solutions. By summarizing the exercise rehabilitation strategies and progress of SARS in 2003, this paper analyzed the differences in clinical indicators and recovery characteristics of severe pneumonia caused by the two viruses, and provided comprehensive exercise guidance and intervention strategies for COVID-19 patients for rehabilitation and nursing by referring to the problems and treatment strategies in the rehabilitation and nursing work of SARS. Read More

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Age Differences in Estimating Physical Activity by Wrist Accelerometry Using Machine Learning.

Sensors (Basel) 2021 May 12;21(10). Epub 2021 May 12.

Department of Aging and Geriatric Research, College of Medicine, University of Florida, Gainesville, FL 32610, USA.

Accelerometer-based fitness trackers and smartwatches are proliferating with incessant attention towards health tracking. Despite their growing popularity, accurately measuring hallmark measures of physical activities has yet to be accomplished in adults of all ages. In this work, we evaluated the performance of four machine learning models: decision tree, random forest, extreme gradient boosting (XGBoost) and least absolute shrinkage and selection operator (LASSO), to estimate the hallmark measures of physical activities in young (20-50 years), middle-aged (50-70 years], and older adults (70-89 years]. Read More

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Are Honey Bees at Risk from Microplastics?

Toxics 2021 May 15;9(5). Epub 2021 May 15.

Toxicology Centre, University of Saskatchewan, Saskatoon, SK S7N 5B3, Canada.

Microplastics (MPs) are ubiquitous and persistent pollutants, and have been detected in a wide variety of media, from soils to aquatic systems. MPs, consisting primarily of polyethylene, polypropylene, and polyacrylamide polymers, have recently been found in 12% of samples of honey collected in Ecuador. Recently, MPs have also been identified in honey bees collected from apiaries in Copenhagen, Denmark, as well as nearby semiurban and rural areas. Read More

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The Effects of the Combination of High-Intensity Interval Training with 3D-Multiple Object Tracking Task on Perceptual-Cognitive Performance: A Randomized Controlled Intervention Trial.

Int J Environ Res Public Health 2021 05 2;18(9). Epub 2021 May 2.

Department of Sport and Exercise Science, Institute of Sport Psychology & Human Movement Performance, University of Stuttgart, 70569 Stuttgart, Germany.

The ability to process goal-related visual information while ignoring goal-irrelevant information is essential for the human attention system. The study aimed to investigate how perceptual-cognitive performance was affected during high-intensity interval training (HIIT) using a 3D-multiple object tracking (3D-MOT) task called Neurotracker (NT). In an experimental design, 42 healthy adults (age = 23. Read More

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