Clin Neurol Neurosurg 2021 Jun 24;207:106781. Epub 2021 Jun 24.
Department of Neurosurgery, Huashan Hospital, Shanghai Medical School, Fudan University, Shanghai, China; Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China; Neurosurgical Institute of Fudan University, Shanghai, China; Shanghai Pituitary Tumor Center, Shanghai, China; State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China; National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China. Electronic address:
Introduction: Previous studies failed to show the benefit of endoscopic surgery over microscopic surgery in terms of early endocrine remission. This study was to investigate whether early endocrine outcomes in patients with GH-secreting pituitary adenoma underwent endoscopic transsphenoidal surgery would be better than those operated by microscopic surgery.
Methods: An acromegaly database collected from 2010 to 2019 in a single institution was used to emulate a randomized trial. Read More