136 results match your criteria fifty client-owned


Prediction of clinically important acquired cardiac disease without an echocardiogram in large breed dogs using a combination of clinical, radiographic and electrocardiographic variables.

J Vet Cardiol 2021 Aug 3. Epub 2021 Aug 3.

Department of Small Animal Clinical Sciences, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, 4474 TAMU, College Station, TX 77843-4474, USA.

Introduction: Large breed (LB) dogs develop dilated cardiomyopathy (DCM) and myxomatous mitral valve disease (MMVD). Echocardiography is required for a definitive diagnosis but is not always available. Our objective was to assess the clinical utility of thoracic radiographs alone and in combination with physical examination and electrocardiography findings for the prediction of clinically important DCM or MMVD in LB dogs. Read More

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Efficacy of medical dissolution for suspected struvite cystoliths in dogs.

J Vet Intern Med 2021 Sep 1. Epub 2021 Sep 1.

Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota, USA.

Background: Medical dissolution of struvite uroliths in dogs is commonly recommended, but data on success rates and complications are limited.

Objectives: To evaluate the efficacy of medical dissolution for suspected struvite cystoliths in dogs.

Animals: Fifty client-owned dogs fed a therapeutic dissolution diet, with or without administration of antimicrobials, for treatment of suspected struvite cystoliths. Read More

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September 2021

Induction of emesis with apomorphine using a novel gingival administration method in dogs.

J Vet Emerg Crit Care (San Antonio) 2021 Aug 25. Epub 2021 Aug 25.

Animal Emergency Centre, Mount Waverley, Victoria, Australia.

Objective: To describe a novel method of inducing emesis in the dog using gingival administration of apomorphine, compare the efficacy of inducing emesis with gingival apomorphine to conjunctival apomorphine, and describe adverse effects associated with the gingival route.

Design: Retrospective study from January 2017 to September 2018.

Setting: Independent all-hours primary and secondary emergency and critical care referral center. Read More

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Non-invasive Assessment of Pulmonary Artery Wave Reflection in Dogs With Suspected Pulmonary Hypertension.

Front Vet Sci 2021 9;8:659194. Epub 2021 Jul 9.

Department of Veterinary Surgery, Tokyo University of Agriculture and Technology, Fuchu-shi, Japan.

Pulmonary arterial wave reflection (PAWR) occurs when the forward blood flow out the right ventricle is reflected by the pulmonary arterial tree, generating a backward wave. PAWR assessed by cardiac catheterization has been used to obtain information regarding pulmonary artery hemodynamics in pulmonary hypertension (PH) in people. However, diagnostic cardiac catheterization is not commonly used in small animal medicine because it is invasive and requires anesthesia. Read More

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Physical activity patterns of free living dogs diagnosed with osteoarthritis.

J Anim Sci 2021 Aug;99(8)

Department of Animal Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.

Osteoarthritis (OA) affects about 90% of dogs > 5 yr of age in the United States, resulting in reduced range of motion, difficulty climbing and jumping, reduced physical activity, and lower quality of life. Our objective was to use activity monitors to measure physical activity and identify how activity counts correlate with age, body weight (BW), body condition score (BCS), serum inflammatory markers, veterinarian pain assessment, and owner perception of pain in free-living dogs with OA. The University of Illinois Institutional Animal Care and Use Committee approved the study and owner consent was received prior to experimentation. Read More

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A clinical retrospective study of Caparinia tripilis (Psoroptidae) mite dermatitis in pet African pygmy hedgehogs (Ateletrix albiventris) in southern Italy.

Vet Dermatol 2021 Oct 27;32(5):434-e115. Epub 2021 Jun 27.

Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, 2015 SW 16th Ave, Gainesville, FL, 32610, USA.

Background: Caparinia tripilis is a common ectoparasitic mite affecting African pygmy hedgehogs, and is associated with pruritus and self-trauma. There have been no published surveys on the prevalence of such mites in pet African pygmy hedgehogs in Italy.

Objective: To evaluate the prevalence and clinical signs of C. Read More

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October 2021

Persistent fontanelles in Chihuahuas. Part I. Distribution and clinical relevance.

J Vet Intern Med 2021 Jul 24;35(4):1834-1847. Epub 2021 May 24.

Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.

Background: The Chihuahua dog breed is known for frequent occurrence of a bregmatic fontanelle on the dorsal skull. A common conception is that this skull defect is a clinically irrelevant finding. No studies, however, describe its prevalence or whether it is accompanied by other persistent fontanelles (PFs). Read More

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Persistent fontanelles in Chihuahuas. Part II: Association with craniocervical junction abnormalities, syringomyelia, and ventricular volume.

J Vet Intern Med 2021 Jul 3;35(4):1848-1856. Epub 2021 May 3.

Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.

Background: Persistent fontanelles (PFs) are, in Chihuahuas, almost ubiquitous. Furthermore, Chihuahuas are predisposed to other craniomorphological abnormalities, including syringomyelia (SM), ventriculomegaly, and craniocervical junction (CCJ) overcrowding resulting in neural tissue deviation. It is, however, undetermined if PFs are more common in dogs with these structural abnormalities, and their etiology is unknown. Read More

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Strain elastography for the assessment of skin nodules in dogs.

Vet Dermatol 2021 Jun 8;32(3):272-e75. Epub 2021 Apr 8.

AniCura Istituto Veterinario Novara, Strada Provinciale 9, Granozzo con Monticello, NO, 28060, Italy.

Background: Strain elastography (SE) is a modern imaging technology that provides an additional way of evaluating the changes in soft tissue elasticity caused by pathophysiological processes. Despite its widespread use in human medicine, only a few studies on the application of SE in veterinary medicine are available.

Objectives: To evaluate the potential usefulness of SE as an integrative imaging model in the standard ultrasound technique to better discriminate between inflammatory and neoplastic skin nodules in dogs. Read More

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Treatment of genitourinary carcinoma in dogs using nonsteroidal anti-inflammatory drugs, mitoxantrone, and radiation therapy: A retrospective study.

J Vet Intern Med 2021 Mar 26;35(2):1052-1061. Epub 2021 Feb 26.

Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA.

Background: Locoregional tumor control and prolonged survival for dogs with genitourinary carcinoma (CGUC) reportedly are achievable using treatment with radiotherapy (RT) with or without adjunctive chemotherapy and nonsteroidal anti-inflammatory drugs (NSAIDs).

Objectives: To characterize event-free and overall survival after treatment of CGUC using NSAIDs, mitoxantrone (MTX), and a standardized RT protocol (57 Gy in 20 fractions).

Animals: Fifty-one client-owned dogs treated between 2008 and 2017. Read More

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Ultrasonographic evaluation of the caudal vena cava in dogs with right-sided heart disease.

J Vet Cardiol 2021 Apr 24;34:80-92. Epub 2021 Jan 24.

Laboratory of Veterinary Surgery, Department of Veterinary Medicine, Faculty of Agriculture, University of Miyazaki, 1-1 Gakuen Kibanadai-nishi, Miyazaki 889-2192, Japan. Electronic address:

Introduction/objectives: In humans with impaired right-sided cardiac function, the caudal vena cava (CVC) diameter serves as a marker of venous congestion. This study aimed to investigate whether ultrasonographic CVC variables could identify the presence of right-sided congestive heart failure (R-CHF) in dogs with right-sided heart disease (RHD).

Animals: Fifty client-owned control dogs and 67 dogs with RHD were enrolled. Read More

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Efficacy of hypophysectomy for the treatment of hypersomatotropism-induced diabetes mellitus in 68 cats.

J Vet Intern Med 2021 Mar 24;35(2):823-833. Epub 2021 Feb 24.

Department of Clinical Science and Services, Royal Veterinary College, Hatfield, UK.

Background: Hypersomatotropism (HST) is an increasingly recognized endocrinopathy in cats and is mostly described associated with diabetes mellitus (DM).

Objectives: To evaluate the efficacy and safety of transsphenoidal hypophysectomy in treating HST and DM in cats.

Animals: Sixty-eight client-owned cats with HST and DM treated by transsphenoidal hypophysectomy. Read More

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Breed predispositions, clinical findings, and prognostic factors for death in dogs with nonregenerative immune-mediated anemia.

J Vet Intern Med 2021 Jan 8;35(1):252-260. Epub 2020 Dec 8.

Department of Clinical Science and Services, Royal Veterinary College, London, UK.

Background: Breed predispositions, survival, and prognostic factors have not been evaluated in dogs with nonregenerative immune-mediated anemia (nrIMA).

Hypothesis/objectives: To describe clinicopathologic variables, evaluate their associations with survival, and determine breed predispositions for dogs with nrIMA.

Animals: Fifty-nine client-owned dogs with nrIMA. Read More

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January 2021

Outcomes and prognostic indicators in 59 paraplegic medium to large breed dogs with extensive epidural hemorrhage secondary to thoracolumbar disc extrusion.

Vet Surg 2021 Apr 19;50(3):527-536. Epub 2021 Feb 19.

North Carolina State University College of Veterinary Medicine, Raleigh, North Carolina.

Objective: To evaluate outcomes and prognostic factors after decompressive hemilaminectomy in paraplegic medium to large breed dogs with extensive epidural hemorrhage (DEEH) and thoracolumbar intervertebral disc extrusion (TL-IVDE).

Study Design: Retrospective, cohort, descriptive study.

Animals: Fifty-nine client-owned dogs. Read More

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Outcome and treatments of dogs with aortic thrombosis: 100 cases (1997-2014).

J Vet Intern Med 2020 Sep 15;34(5):1759-1767. Epub 2020 Aug 15.

Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA.

Background: Aortic thrombosis (ATh) is an uncommon condition in dogs, with limited understanding of risks factors, outcomes, and treatments.

Objectives/hypothesis: To describe potential risk factors, outcome, and treatments in dogs with ATh.

Animals: Client-owned dogs with a diagnosis of ATh based on ultrasonographic or gross necropsy examination. Read More

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September 2020

Topical treatment of equine sarcoids with imiquimod 5% cream or Sanguinaria canadensis and zinc chloride - an open prospective study.

Vet Dermatol 2020 Dec 5;31(6):471-e126. Epub 2020 Oct 5.

Department of Clinical Sciences, University of Agriculture, Box 7054, Uppsala, 750 07, Sweden.

Background: Equine sarcoids are the most prevalent skin neoplasm in horses worldwide. Although several treatments are available, none are consistently effective and recurrence is common.

Objectives: To evaluate the efficacy and safety of topical imiquimod 5% cream and Sanguinaria canadensis + zinc chloride for treatment of equine sarcoids and investigate possible systemic effects on distant untreated sarcoids. Read More

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December 2020

Punctate fluorescein staining scores in dogs with or without aqueous tear deficiency.

Vet Ophthalmol 2021 Jan 22;24(1):28-36. Epub 2020 Sep 22.

Itoh Clinic, Minuma-Ku, Saitama, Japan.

Objective: To compare the superficial punctate fluorescein staining in dogs with and without aqueous tear deficiency.

Procedures: An eye from each client-owned dogs presented to Triangle Animal Eye Clinic between January and December 2018 underwent tear and ocular surface tests, which included the Schirmer tear test (STT), phenol red thread test (PRT), and strip meniscometry tube tear test (SMT). Punctate fluorescein staining of the cornea (PFS-C) and the upper palpebral conjunctiva (PFS-UPC) were also performed. Read More

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January 2021

Efficacy of adding ramipril (VAsotop) to the combination of furosemide (Lasix) and pimobendan (VEtmedin) in dogs with mitral valve degeneration: The VALVE trial.

J Vet Intern Med 2020 Nov 18;34(6):2232-2241. Epub 2020 Sep 18.

Division of Cardiology, Department of Small Animals, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.

Background: Triple therapy (TT) consisting of furosemide, pimobendan, and an angiotensin-converting enzyme inhibitor (ACEI) frequently is recommended for the treatment of congestive heart failure (CHF) attributable to myxomatous mitral valve disease (MMVD). However, the effect of adding an ACEI to the combination of pimobendan and furosemide (dual therapy [DT]) so far has not been evaluated prospectively.

Hypothesis: Triple therapy will extend survival time compared to DT in dogs with CHF secondary to MMVD. Read More

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November 2020

Investigation of hemotropic Mycoplasma spp. genotypes in client-owned cats in Thailand.

Vet Microbiol 2020 Aug 25;247:108765. Epub 2020 Jun 25.

Faculty of Veterinary Medicine, Kasetsart University, Bangkok, Thailand. Electronic address:

The genetic information for three feline hemoplasmas is limited in Southeast Asia. According to the limited genetic data, this study modified a nested-PCR method targeting the 16S rRNA gene by designing a novel primary forward degenerate primer. Two hundred and thirty-one archived DNA extracts from the blood of client-owned cats with a variety of diseases were used. Read More

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Detecting and recording cardiac murmurs in clinically healthy puppies in first opinion veterinary practice at the first health check.

Acta Vet Scand 2020 Jun 25;62(1):37. Epub 2020 Jun 25.

Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 108, 3584 CM, Utrecht, The Netherlands.

Background: The frequency that cardiac murmurs are identified and recorded in first opinion veterinary practices at the first health check in puppies is unknown. The aims of the study were to assess the agreement between first opinion veterinary practitioners, a veterinary student and a veterinary cardiology specialist on detecting murmurs, and to establish whether abnormal auscultation findings had been recorded in the health certificates of clinically healthy puppies. The study included prospective and retrospective investigations, where the prospectively collected auscultation findings from a veterinary cardiology specialist and a trained veterinary student were compared to auscultation findings recorded by first opinion veterinary practitioners. Read More

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Clinical findings and outcomes of 153 dogs surgically treated for intestinal intussusceptions.

Vet Surg 2020 Jul 16;49(5):870-878. Epub 2020 May 16.

VCA Canada - Alta Vista Animal Hospital, Ottawa, Ontario, Canada.

Objective: To describe perioperative characteristics and outcomes of dogs surgically treated for intestinal intussusception.

Study Design: Multi-institutional, retrospective study.

Animals: One hundred fifty-three client-owned dogs with intestinal intussusception. Read More

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Conjunctival staining with lissamine green as a predictor of tear film deficiency in dogs.

Vet Ophthalmol 2020 Jul 9;23(4):624-631. Epub 2020 May 9.

Section of Ophthalmology, Department of Clinical Sciences & Advanced Medicine, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania.

Objective: To evaluate a grading scheme for conjunctival staining patterns with lissamine green ocular dye in the diagnosis of tear film deficiencies in dogs.

Procedures: Client-owned and research colony dogs were enrolled in a prospective study between February and October 2018 in which slit-lamp biomicroscopy, Schirmer tear test (STT), tear film breakup time (TFBUT), conjunctival lissamine green staining (LGS), and intraocular pressure (IOP) measurement were performed in both eyes of all dogs. Lissamine green staining of the temporal bulbar conjunctiva was graded from 0-3, with a higher grade corresponding to an increased stain intensity. Read More

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Transurethral cystoscopy in dogs with recurrent urinary tract infections: Retrospective study (2011-2018).

J Vet Intern Med 2020 Mar 26;34(2):790-796. Epub 2020 Feb 26.

Department of Clinical Sciences, School of Veterinary Medicine, University of Montreal, Saint-Hyacinthe, Quebec, Canada.

Background: Urinary tract infections (UTIs) are common in female dogs and recurrent infections often require investigation by transurethral cystoscopy.

Hypothesis/objectives: Describe the findings of transurethral cystoscopy in dogs presented for recurrent urinary tract infections (RUTI).

Animals: Fifty-three client-owned dogs with RUTI were included in the study. Read More

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Prospective evaluation of the influence of sampling method on bacterial culture results and antimicrobial selection in 52 dogs with infected wounds.

J Vet Emerg Crit Care (San Antonio) 2020 Mar 14;30(2):149-158. Epub 2020 Feb 14.

Western University of Health Sciences College of Veterinary Medicine, Pomona, CA.

Objective: To determine the influence of sampling methods on culture results and selection of antimicrobials for treating infected wounds in dogs.

Design: Prospective study from January to July 2016.

Setting: Three private multispecialty referral centers. Read More

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Associations among echocardiography, cardiac biomarkers, insulin metabolism, morphology, and inflammation in cats with asymptomatic hypertrophic cardiomyopathy.

J Vet Intern Med 2020 Mar 11;34(2):591-599. Epub 2020 Feb 11.

Department of Small Animal Clinical Science, Institute of Veterinary Science, Leahurst, University of Liverpool, Neston, UK.

Background: Insulin, insulin-like growth factor-1 (IGF-1), and inflammation possibly are involved in cats with asymptomatic hypertrophic cardiomyopathy (aHCM).

Objectives: To evaluate echocardiography, morphology, cardiac and inflammatory markers, insulin and IGF-1 in cats with aHCM.

Animals: Fifty-one client-owned cats with aHCM. Read More

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Bacterial infection before and after stent placement in dogs with tracheal collapse syndrome.

J Vet Intern Med 2020 Mar 24;34(2):725-733. Epub 2020 Jan 24.

Lamb Statistical Consulting LLC, West Saint Paul, Minnesota.

Background: Dogs with tracheal stents often have positive airway bacterial cultures. The pathogenicity of these organisms and risk factors for infection have not been investigated.

Objective: Describe bacterial infection in dogs with tracheal collapse before and after tracheal stent placement. Read More

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Comparison of cerebellomedullary and lumbar cerebrospinal fluid analysis in dogs with neurological disease.

J Vet Intern Med 2020 Mar 18;34(2):838-843. Epub 2020 Jan 18.

Department of Veterinary Pathobiology, University of Illinois at Urbana-Champaign, Urbana, Illinois.

Background: Cerebrospinal fluid (CSF) analysis aids in categorizing underlying disease processes in patients with neurologic disease. Convention suggests that CSF should be collected caudal to the lesion. However, little evidence exists to justify this assertion. Read More

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Evaluation of benazepril in cats with heart disease in a prospective, randomized, blinded, placebo-controlled clinical trial.

J Vet Intern Med 2019 Nov 27;33(6):2559-2571. Epub 2019 Sep 27.

Clinique Vétérinaire du Clos des Camélias, Colombes, France.

Background: Heart disease is an important cause of morbidity and mortality in cats, but there is limited evidence of the benefit of any medication.

Hypothesis: The angiotensin-converting enzyme inhibitor benazepril would delay the time to treatment failure in cats with heart disease of various etiologies.

Animals: One hundred fifty-one client-owned cats. Read More

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November 2019

Clinical characteristics and short-term outcomes for rabbits with signs of gastrointestinal tract dysfunction: 117 cases (2014-2016).

J Am Vet Med Assoc 2019 10;255(7):837-845

Objective: To describe the clinical findings and short-term outcomes for rabbits with signs of gastrointestinal tract dysfunction or rabbit gastrointestinal syndrome (RGIS).

Animals: 117 client-owned rabbits.

Procedures: The electronic medical records database of a veterinary teaching hospital was searched to identify rabbits that were examined because of altered or absent food intake and decreased or absent fecal output between June 1, 2014, and June 30, 2016. Read More

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October 2019

A prospective randomized study of efficacy of 2 treatment protocols in preventing recurrence of clinical signs in 51 male cats with obstructive idiopathic cystitis.

J Vet Intern Med 2019 Sep 10;33(5):2117-2123. Epub 2019 Aug 10.

Veterinary Teaching Hospital and Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, Rehovot, Israel.

Background: Urethral obstruction (UO) is a common complication of feline idiopathic cystitis (FIC). Robust treatment recommendations to prevent its recurrence are scarce.

Objectives: To evaluate meloxicam treatment for prevention of clinical recrudescence in male cats with obstructive FIC. Read More

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September 2019