37 results match your criteria fif plan


Field-in-Field Technique With Intrafractionally Modulated Junction Shifts for Craniospinal Irradiation Planning With Three-Dimensional Conformal Radiation Therapy.

Cureus 2021 Apr 28;13(4):e14744. Epub 2021 Apr 28.

Oncology, Ziauddin University, Karachi, PAK.

Background: Planning craniospinal irradiation (CSI) with ''field-in-field'' (FIF) homogenization technique in combination with daily, intrafractional modulation of the field junctions is needed to avoid spinal cord overdose. Photon-based techniques for CSI may result in dose inhomogeneity within the treatment volume and usually require a weekly manual shift of the field junctions to minimize the possibility of spinal cord overdose. Nowadays, FIF technique is used to feather out the dose inhomogeneity caused by multiple fields. Read More

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Dosimetric assessment of brass mesh bolus and transparent polymer-gel type bolus for commonly used breast treatment delivery techniques.

Med Dosim 2021 Jan 31. Epub 2021 Jan 31.

Department of Radiation Oncology, Stritch School of Medicine, Cardinal Bernardine Cancer Center, Loyola University Chicago, Maywood, IL, 60637 USA. Electronic address:

We investigated skin dose enhancements of brass mesh bolus (BMB) and a recently developed transparent polymer-gel bolus (PGB) for clinically relevant breast treatment delivery techniques. The dose enhancement of the breast surface with BMB and PGB were compared to that of tissue-equivalent bolus. Three breast treatment plans were generated on CT scans of an anthropomorphic chest phantom: tangential step-and-shoot 3D conformal (3DCRT) planned using Field-in-Field (FiF), tangential sliding-window 3DCRT using Electronic Compensator (EC), and volumetric modulated arc therapy (VMAT). Read More

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January 2021

Assessment of planning reproducibility in three-dimensional field-in-field radiotherapy technique for breast cancer: impact of surgery-simulation interval.

Sci Rep 2021 Jan 15;11(1):1556. Epub 2021 Jan 15.

Division of Medical Oncology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

The three-dimensional field-in-field (3-D FIF) technique for radiotherapy is an advanced, state-of-the-art method that uses multileaf collimators to generate a homogeneous and conformal dose distribution via segmental subfields. The purpose of this study is to evaluate the dosimetric reproducibility of 3-D FIF plans using the original simulation computed tomography (iCT) scans and re-simulation CT (rCT) scans for whole breast irradiation (WBI) schedule. This study enrolled a total of 34 patients. Read More

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January 2021

Plan quality assessment of modern radiotherapy delivery techniques in left-sided breast cancer: an analysis stratified by target delineation guidelines.

BJR Open 2020 11;2(1):20200007. Epub 2020 Dec 11.

Department of Radiation Oncology, Rajiv Gandhi Cancer Institute and Research Centre, Sector 5, Rohini, New Delhi, India.

Objective: This study compares planning techniques stratified by consensus delineation guidelines in patients undergoing whole-breast radiotherapy based on an objective plan quality assessment scale.

Methods: 10 patients with left-sided breast cancer were randomly selected, and target delineation for intact breast was performed using Tangent (RTOG 0413), ESTRO, and RTOG guidelines. Consensus Plan Quality Metric (PQM) scoring was defined and communicated to the physicist before commencing treatment planning. Read More

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December 2020

Postmastectomy Radiation Therapy Planning After Immediate Implant-based Reconstruction Using the European Society for Radiotherapy and Oncology-Advisory Committee in Radiation Oncology Practice Consensus Guidelines for Target Volume Delineation.

Clin Oncol (R Coll Radiol) 2021 01 26;33(1):20-29. Epub 2020 Sep 26.

Department of Experimental Clinical Oncology, Aarhus University Hospital, Aarhus, Denmark.

Aims: To evaluate how common radiation therapy techniques perform in the setting of the new European Society for Radiotherapy and Oncology-Advisory Committee in Radiation Oncology Practice (ESTRO-ACROP) delineation recommendations for immediate breast reconstruction (IBR).

Materials And Methods: Seven Danish radiation therapy centres and six international European centres participated in this project. Two breast cancer cases (one left-sided and one right-sided) with a retropectoral implant were chosen for radiation therapy planning using deep-inspiration breath-hold. Read More

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January 2021

Skin Toxicity in Early Breast Cancer Patients Treated with Field-In-Field Breast Intensity-Modulated Radiotherapy versus Helical Inverse Breast Intensity-Modulated Radiotherapy: Results of a Phase III Randomised Controlled Trial.

Clin Oncol (R Coll Radiol) 2021 01 22;33(1):30-39. Epub 2020 Jul 22.

Division of Radiation Oncology, Department of Oncology, University of Alberta & Cross Cancer Institute, Edmonton, Alberta, Canada. Electronic address:

Aims: Skin toxicity is a common adverse effect of breast radiotherapy. We investigated whether inverse-planned intensity-modulated radiotherapy (IMRT) would reduce the incidence of skin toxicity compared with forward field-in-field breast IMRT (FiF-IMRT) in early stage breast cancer.

Materials And Methods: This phase III randomised controlled trial compared whole-breast irradiation with either FiF-IMRT or helical tomotherapy IMRT (HT-IMRT), with skin toxicity as the primary end point. Read More

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January 2021

Dosimetric study of whole-brain irradiation with high-energy photon beams for dose reduction to the scalp.

Br J Radiol 2020 Oct 21;93(1114):20200159. Epub 2020 Jul 21.

Department of Radiation Oncology, Keio University School of Medicine, Shinjuku, Tokyo, Japan.

Objective: To evaluate the efficiency of high-energy photons for mitigating alopecia due to whole-brain irradiation (WBRT).

Methods: Planning CT data from 10 patients who received WBRT were collected. We prepared 4 WBRT plans that used 6 or 15 MV photon beams, with or without use of a field-in-field (FiF) technique, and compared outcomes using a treatment planning system. Read More

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October 2020

Dosimetric comparison of helical tomotherapy, volumetric-modulated arc therapy, intensity-modulated radiotherapy, and field-in-field technique for synchronous bilateral breast cancer.

Med Dosim 2020 Autumn;45(3):271-277. Epub 2020 Feb 29.

Department of Radiation Oncology, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Department of Radiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. Electronic address:

Purpose: To compare the dosimetric characteristics of helical tomotherapy (HT), volumetric-modulated arc therapy (VMAT), intensity-modulated radiotherapy (IMRT), and tangential field-in-field technique (FIF) for the treatment of synchronous bilateral breast cancer (SBBC).

Methods And Materials: Ten patients with early-stage unilateral breast cancer were selected for simulating the patients with SBBC in this retrospective analysis. Treatment plans with HT, VMAT, IMRT, and FIF were generated for each patient with a total dose of 50. Read More

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Optimization of autogenerated chest-wall radiation treatment plans developed for postmastectomy breast cancer patients in underserved clinics.

Med Dosim 2020 Spring;45(1):102-107. Epub 2020 Jan 16.

The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

Over the past decade, several strides have been made to improve the management of breast cancer in developing countries; however, there are still obstacles present. In the area of radiation therapy, these hurdles include limited access to radiotherapy treatment and scarcity of oncology specialists. In an effort to reduce inequities in cancer care while improving patient outcomes, our research is focused on developing automated postmastectomy radiation therapy (PMRT) plans for breast cancer patients in these underserved communities that can be further improved upon through treatment planning system (TPS) specific optimization guidelines. Read More

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December 2020

Effects of image distortion and Hounsfield unit variations on radiation treatment plans: An extended field-of-view reconstruction in a large bore CT scanner.

Sci Rep 2020 01 16;10(1):473. Epub 2020 Jan 16.

Department of Radiation Oncology, Konkuk University Medical Center, Seoul, Republic of Korea.

This study aimed to evaluate the effect of image distortion and Hounsfield unit (HU) variation due to the extended field-of-view (eFOV) of the large-bore (LB) computed tomography (CT) on dose distribution. Both home-made inhomogeneity and breast phantoms were scanned at the geometric center position and four different offset positions. We also performed dose optimizations based on different breast phantom CT sets for evaluating the effects of image artifacts on the intensity-modulated radiation techniques. Read More

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January 2020

Field-in-field breast planning for a jawless, double-stack MLC LINAC using flattening-filter-free beams.

J Appl Clin Med Phys 2019 Nov 16;20(11):14-26. Epub 2019 Oct 16.

Department of Radiation Oncology, Washington University, St. Louis, MO, 63110, USA.

Background: This study intends to develop an efficient field-in-field (FiF) planning technique with the Eclipse treatment planning system (TPS) to determine the feasibility of using the Halcyon treatment delivery system for 3D treatment of breast cancer.

Methods: Ten treatment plans were prepared on the Halcyon treatment planning system and compared to the same patients' clinically delivered TrueBeam plans which used flattened 6 MV and 10 MV beams. Patients selected for this study were treated via simple, tangential breast irradiation and did not receive radiotherapy of the supraclavicular or internal mammary lymph nodes. Read More

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November 2019

Automated Field-In-Field (FIF) Plan Framework Combining Scripting Application Programming Interface and User-Executed Program for Breast Forward IMRT.

Technol Cancer Res Treat 2018 01;17:1533033818810391

1 Department of Radiation Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Purpose: To develop an one-click option on treatment planning system that enables for the automated breast FIF planning by combining the Eclipse Scripting application programming interfaces and user-executed programming in Windows.

Methods: Scripting application programming interfaces were designed to promote automation in clinical workflow associated with radiation oncology. However, scripting cannot provide all functions that users want to perform. Read More

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January 2018

A treatment planning comparison of contemporary photon-based radiation techniques for breast cancer.

Phys Imaging Radiat Oncol 2018 Jul 8;7:32-38. Epub 2018 Sep 8.

Institute of Radiation Physics, Lausanne University Hospital, Lausanne, Switzerland.

Background And Purpose: Adjuvant radiation therapy (RT) of the whole breast (WB) is still the standard treatment for early breast cancer. A variety of radiation techniques is currently available according to different delivery strategies. This study aims to provide a comparison of six treatment planning strategies commonly adopted for breast-conserving adjuvant RT and to use the Pareto concept in an attempt to assess the degree of plan optimization. Read More

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Breast-conserving radiotherapy with simultaneous integrated boost; field-in-field three-dimensional conformal radiotherapy versus inverse intensity-modulated radiotherapy - A dosimetric comparison: Do we need intensity-modulated radiotherapy?

South Asian J Cancer 2018 Jul-Sep;7(3):163-166

Department of Radiotherapy, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka, India.

Background And Purpose: To examine the feasibility of improving breast-conserving radiotherapy with simultaneous integrated boost (SIB) and analyzing the efficiency of forward versus inverse intensity-modulated radiotherapy (IMRT) techniques in providing the same.

Materials And Methods: Three-dimensional conformal radiotherapy (3DCRT) field-in-field (FIF) plans with simultaneous and sequential boost and IMRT SIB plans were generated for the datasets of 20 patients who had undergone breast-conserving surgery. The 3 plans were compared dosimetrically for efficiency in terms of planning target volume (PTV) coverage (PTV 95%), homogeneity and conformity, dose delivered to ipsilateral/contralateral lungs (I/L: V10, V20, C/L: Vmean, V5), heart and contralateral breast (Vmean, V30 for heart and Vmean, V1, V5 for C/L breast). Read More

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Dosimetric comparison of three intensity-modulated radiation therapies for left breast cancer after breast-conserving surgery.

J Appl Clin Med Phys 2018 May 10;19(3):79-86. Epub 2018 Mar 10.

Department of Radiation Oncology, PLA General Hospital, Beijing, China.

Purpose: This study aimed to evaluate dosimetric differences of intensity-modulated radiation therapy (IMRT) in target and normal tissues after breast-conserving surgery.

Methods: IMRT five-field plan I, IMRT six-field plan II, and field-in-field-direct machine parameter optimization-IMRT plan III were designed for each of the 50 patients. One-way analysis of variance was performed to compare differences, and P < 0. Read More

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Usefulness of the dual energy field-in-field technique in breast tangential radiotherapy.

Radiol Med 2016 Apr 11;121(4):323-6. Epub 2015 Dec 11.

Department of Radiology, Gifu University Hospital, Yanagido 1-1, Gifu, 501-1194, Japan.

Purpose: In the field-in-field (FIF) technique in breast tangential radiotherapy, the energy of the subfield is usually the same as the energy of the main field. However, some studies have applied 10-18 MV to subfields in patients with large breasts. We compared two FIF plans in 66 breast cancer patients: in one, the energy of the subfield was the same as that of the main field (the mono energy plan); in the other, it was higher (the dual energy plan). Read More

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Evaluation of the field-in-field technique with lung blocks for breast tangential radiotherapy.

Nagoya J Med Sci 2015 Aug;77(3):339-45

Department of Radiology, Gifu University Graduate School of Medicine, Gifu, Japan ; Department of Radiology, Gifu University Hospital, Gifu, Japan.

Several studies have reported the advantages of the field-in-field (FIF) technique in breast radiotherapy, including dose reduction in the lungs by using lung field blocks. We evaluated the FIF technique with lung blocks for breast tangential radiotherapy. Sixteen patients underwent free breathing (FB) computed tomography (CT), followed by two CT procedures performed during breath hold after light inhalation (IN) and light exhalation (EX). Read More

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Single-isocenter hybrid IMRT plans versus two-isocenter conventional plans and impact of intrafraction motion for the treatment of breast cancer with supraclavicular lymph nodes involvement.

J Appl Clin Med Phys 2015 07 8;16(4):31–39. Epub 2015 Jul 8.

Georgia Regents University.

The purpose of this study was to compare the single-isocenter, four-field hybrid IMRT with the two-isocenter techniques to treat the whole breast and supraclavicular fields and to investigate the intrafraction motions in both techniques in the superior direction. Fifteen breast cancer patients who underwent lumpectomy and adjuvant radiation to the whole breast and supraclavicular (SCV) fossa at our institution were selected for this study. Two planning techniques were compared for the treatment of the breast and SCV lymph nodes. Read More

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Use of tomotherapy in treatment of synchronous bilateral breast cancer: dosimetric comparison study.

Br J Radiol 2015 Apr 21;88(1048):20140612. Epub 2015 Jan 21.

1 Department of Radiation Oncology, Tata Memorial Hospital, Mumbai, India.

Objective: Synchronous malignancy in both breasts is a rare incidence. The present study aims at dosimetric comparison of conventional bitangential radiotherapy (RT) technique with conventional [field-in-field (FIF)] and rotational [Helical TomoTherapy(®) and TomoDirect™ (TD); Accuray Inc., Sunnyvale, CA] intensity-modulated RT for patients with synchronous bilateral breast cancer (SBBC). Read More

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Effects of geometrical uncertainties on whole breast radiotherapy: a comparison of four different techniques.

J Breast Cancer 2014 Jun 27;17(2):157-60. Epub 2014 Jun 27.

Department of Radiation Oncology, St. Luke's International Hospital, Tokyo, Japan.

Purpose: The purpose of this study was to quantify the target coverage, homogeneity, and robustness of the dose distributions against geometrical uncertainties associated with four whole breast radiotherapy techniques.

Methods: The study was based on the planning-computed tomography-datasets of 20 patients who underwent whole breast radiotherapy. A total of four treatment plans (wedge, field-in-field [FIF], hybrid intensity-modulated radiotherapy [IMRT], and full IMRT) were created for each patient. Read More

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Impact of respiratory motion on breast tangential radiotherapy using the field-in-field technique compared to irradiation using physical wedges.

Radiol Oncol 2014 Mar 22;48(1):94-8. Epub 2014 Jan 22.

Department of Radiology, Gifu University Hospital, Yanagido 1-1, Gifu, Japan.

Background: This study aimed to evaluate whether the field-in-field (FIF) technique was more vulnerable to the impact of respiratory motion than irradiation using physical wedges (PWs).

Patients And Methods: Ten patients with early stage breast cancer were enrolled. Computed tomography (CT) was performed during free breathing (FB). Read More

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Determination of the optimal method for the field-in-field technique in breast tangential radiotherapy.

J Radiat Res 2014 Jul 16;55(4):769-73. Epub 2014 Feb 16.

Department of Radiology, Gifu University Hospital, Yanagido 1-1, Gifu 501-1194, Japan.

Several studies have reported the usefulness of the field-in-field (FIF) technique in breast radiotherapy. However, the methods for the FIF technique used in these studies vary. These methods were classified into three categories. Read More

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Field-in-field plan does not improve the dosimetric outcome compared with the wedged beams plan for breast cancer radiotherapy.

Med Dosim 2014 12;39(1):79-82. Epub 2013 Dec 12.

Department of General Surgery, Zuoying Branch of Kaohsiung Armed Forces General Hospital, Kaohsiung City, Taiwan, ROC.

To evaluate and compare the dosimetry of field-in-field (FIF) and wedged beams (WB) techniques for patients with breast cancer receiving adjuvant radiotherapy after conservative surgery. A total of 89 patients with breast cancer participated in this study. Each patient received a computed tomography-based treatment plan with opposed tangential fields. Read More

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September 2014

The impact of flattening-filter-free beam technology on 3D conformal RT.

Radiat Oncol 2013 May 31;8:133. Epub 2013 May 31.

Department of Radiation Therapy and Radiooncology, Radiologische Allianz Hamburg, Hamburg, Germany.

Background: The removal of the flattening filter (FF) leads to non-uniform fluence distribution with a considerable increase in dose rate. It is possible to adapt FFF beams (flattening-filter-free) in 3D conformal radiation therapy (3D CRT) by using field in field techniques (FiF). The aim of this retrospective study is to clarify whether the quality of 3D CRT plans is influenced by the use of FFF beams. Read More

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A comparative dosimetric study for treating left-sided breast cancer for small breast size using five different radiotherapy techniques: conventional tangential field, filed-in-filed, tangential-IMRT, multi-beam IMRT and VMAT.

Radiat Oncol 2013 Apr 15;8:89. Epub 2013 Apr 15.

Department of Radiation Oncology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, People's Republic of China.

Background And Purposes: To compare the dosimetry for the left-sided breast cancer treatment using five different radiotherapy techniques.

Materials And Methods: Twenty patients with left sided breast cancer were treated with conservative surgery followed by radiotherapy. They were planned using five different radiotherapy techniques, including: 1) conventional tangential wedge-based fields (TW); 2) field-in-field (FIF) technique; 3) tangential inverse planning intensity-modulated radiation therapy (T-IMRT); 4) multi-field IMRT (M-IMRT); and 5) volumetric modulated arc therapy (VMAT). Read More

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Dosimetric comparison of intensity modulated radiotherapy isocentric field plans and field in field (FIF) forward plans in the treatment of breast cancer.

J Med Phys 2013 Jan;38(1):22-9

Department of Radiotherapy, Royal Hospital, Muscat, Oman.

The present study is aimed at comparing the planning and delivery efficiency between three-dimensional conformal radiotherapy (3D-CRT), field-in-field, forward planned, intensity modulated radiotherapy (FIF-FP-IMRT), and inverse planned intensity modulated radiotherapy (IP-IMRT). Treatment plans of 20 patients with left-sided breast cancer, 10 post-mastectomy treated to a prescribed dose of 45 Gy to the chest wall in 20 fractions, and 10 post-breast-conserving surgery to a prescribed dose of 50 Gy to the whole breast in 25 fractions, with 3D-CRT were selected. The FiF-FP-IMRT plans were created by combining two open fields with three to four segments in two tangential beam directions. Read More

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January 2013

The dosimetric impact of respiratory breast movement and daily setup error on tangential whole breast irradiation using conventional wedge, field-in-field and irregular surface compensator techniques.

J Radiat Res 2013 Jan 1;54(1):157-65. Epub 2012 Aug 1.

Department of Radiology, Faculty of Medicine, Juntendo University, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.

To evaluate the dosimetric impact of respiratory breast motion and daily setup error on whole breast irradiation (WBI) using three irradiation techniques; conventional wedge (CW), field-in-field (FIF) and irregular surface compensator (ISC). WBI was planned for 16 breast cancer patients. The dose indices for evaluated clinical target volume (CTV(evl)), lung, and body were evaluated. Read More

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January 2013

SU-E-T-440: Dosimetry Parameter Comparison between Field-In-Field Technique and Conventional Physical Wedge Technique for Whole Breast Radiation Treatment.

Authors:
M Su V Ayzenberg W Li

Med Phys 2012 Jun;39(6Part16):3806

Mount Sinai School of Medicine, Elmhurst, NY.

Purpose: To compare an advantage/disadvantage between Field-in-Field (FIF) technique and conventional physical wedge (PW) technique for a whole breast (WB) tangential field irradiation.

Methods And Materials: Total 86 patients were included in this study. 46 of them were left breast cancer cases. Read More

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Evaluation of field-in-field technique for total body irradiation.

Int J Radiat Oncol Biol Phys 2012 Aug 26;83(5):1641-8. Epub 2012 Jan 26.

Department of Radiation Oncology, Baskent University Faculty of Medicine, Adana, Turkey.

Purpose: To evaluate the clinical use of a field-in-field (FIF) technique for total body irradiation (TBI) using a treatment-planning system (TPS) and to verify TPS results with in vivo dose measurements using metal-oxide-semiconductor field-effect transistor (MOSFET) detectors.

Methods And Materials: Clinical and dosimetric data of 10 patients treated with TBI were assessed. Certain radiation parameters were measured using homogenous and regular phantoms at an extended distance of 380 cm, and the results were compared with data from a conventional standard distance of 100 cm. Read More

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Dosimetric comparison of the field-in-field technique and tangential wedged beams for breast irradiation.

Jpn J Radiol 2012 Apr 21;30(3):218-26. Epub 2011 Dec 21.

Department of Radiation Oncology, Adana Research and Treatment Centre, Baskent University Faculty of Medicine, 01120 Adana, Turkey.

Purpose: To analyze tangential wedged beam and field-in-field (FIF) technique doses using dose-volume histograms and conformality indices for target volume and healthy tissues within the irradiated volume.

Materials And Methods: Thirty patients treated with breast-conserving surgery and postoperative whole breast radiotherapy were enrolled. Three plans were generated: a standard tangential plan with either one outer field wedge or bilateral wedges, and an FIF plan. Read More

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