3,633 results match your criteria fibroadenoma

Primary breast angiosarcoma resembling a common benign tumor: A case report.

Ann Med Surg (Lond) 2021 May 10;65:102281. Epub 2021 Apr 10.

Department of Surgery, Al-Mouwassat University Hospital, Damascus University, Faculty of Medicine, Damascus, Syria.

Introduction And Importance: The breast angiosarcoma is a rare malignant vascular neoplasm; it represents nearly 0.05% of all breast cancers. Clinically, it could look like a haemangioma or pseudoangiomatous hyperplasia. Read More

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Hybrid Spectral-IRDx: Near-IR and Ultrasound Attenuation System for Differentiating Breast Cancer from Adjacent Normal Tissue.

IEEE Trans Biomed Eng 2021 May 4;PP. Epub 2021 May 4.

Objective: While performing surgical excision for breast cancer (lumpectomy), it is important to ensure a clear margin of normal tissue around the cancer to achieve complete resection. The current standard is histopathology; however, it is time-consuming and labour-intensive requiring skilled personnel.

Method: We describe a Hybrid Spectral-IRDx - a combination of the previously reported Spectral-IRDx tool with multimodal ultrasound and NIR spectroscopy techniques. Read More

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Differential diagnosis between small breast phyllodes tumors and fibroadenomas using artificial intelligence and ultrasound data.

Quant Imaging Med Surg 2021 May;11(5):2052-2061

Department of Ultrasound, Peking University People's Hospital, Beijing, China.

Background: It is challenging to differentiate between phyllodes tumors (PTs) and fibroadenomas (FAs). Artificial intelligence (AI) can provide quantitative information regarding the morphology and textural features of lesions. This study attempted to use AI to evaluate the ultrasonic images of PTs and FAs and to explore the diagnostic performance of AI features in the differential diagnosis of PTs and FAs. Read More

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Emergency embolization for breast pseudoaneurysm following vacuum-assisted biopsy: a case report.

Pan Afr Med J 2021 8;38:135. Epub 2021 Feb 8.

Department of Radiology, Ha Noi Medical University Hospital, Ha Noi, Vietnam.

Vacuum-assisted breast biopsy (VABB) is a minimally invasive procedure and has become an important treatment method. Although VABB is a minimally invasive procedure, it might cause complications, particularly those associated with blood vessels. In this article, we aimed to describe a 35-year-old female who experienced pseudoaneurysm post-VABB and was successfully treated with embolization. Read More

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Early onset, multiple, bilateral fibroadenomas of the breast: a case report.

BMC Womens Health 2021 Apr 21;21(1):170. Epub 2021 Apr 21.

Department of Surgery, Division of Surgical Oncology, University of California San Francisco, San Francisco, CA, USA.

Background: While fibroadenomas are common in the general population, affecting 10-20% of women, they are rarely early-onset, multiple, and bilateral.

Case Presentation: An 18-year-old woman presented with a 6 year history of multiple, bilateral breast masses without family history of breast disease. Magnetic resonance imaging (MRI, Fig. Read More

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Clinical practice guideline for breast fibroadenoma: Chinese Society of Breast Surgery (CSBrS) practice guideline 2021.

Chin Med J (Engl) 2021 Apr 15;134(9):1014-1016. Epub 2021 Apr 15.

Department of Breast Center, Peking University People's Hospital, Beijing 100044, China.

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Management of Pediatric Breast Masses: A Multi-institutional Retrospective Cohort Study.

J Surg Res 2021 Apr 9;264:309-315. Epub 2021 Apr 9.

Center for Surgical Outcomes Research, Nationwide Children's Hospital, Columbus, Ohio; Department of Surgery, Division of Pediatric Surgery, The Ohio State University College of Medicine, Nationwide Children's Hospital, Columbus, Ohio.

Background: The objective of our study was to describe the workup, management, and outcomes of pediatric patients with breast masses undergoing operative intervention.

Materials And Methods: A retrospective cohort study was conducted of girls 10-21 y of age who underwent surgery for a breast mass across 11 children's hospitals from 2011 to 2016. Demographic and clinical characteristics were summarized. Read More

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Surgery for fibroadenoma arising from axillary accessory breast.

Sung Ryul Lee

BMC Womens Health 2021 Apr 7;21(1):139. Epub 2021 Apr 7.

Department of Surgery, Damsoyu Hospital, 234 Hakdong-ro, Gangnam-gu, Seoul, Republic of Korea.

Background: Patients with fibroadenomas in axillary accessory breasts (AABs) have a palpable mass, cyclic axillary pain, and aesthetic concerns that must be addressed. We compared the baseline patient characteristics, AAB characteristics, and surgical outcomes of patients with AABs with and without fibroadenomas undergoing surgical excision. We also monitored the patients for recurrence of axillary fibroadenomas. Read More

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Development of a digital breast phantom for photoacoustic computed tomography.

Biomed Opt Express 2021 Mar 10;12(3):1391-1406. Epub 2021 Feb 10.

The Department of Electronic Engineering, Tsinghua University, Beijing, 100084, China.

Photoacoustic (PA) imaging provides morphological and functional information about angiogenesis and thus is potentially suitable for breast cancer diagnosis. However, the development of PA breast imaging has been hindered by inadequate patients and a lack of ground truth images. Here, we report a digital breast phantom with realistic acoustic and optical properties, with which a digital PA-ultrasound imaging pipeline is developed to create a diverse pool of virtual patients with three types of masses: ductal carcinoma in situ, invasive breast cancer, and fibroadenoma. Read More

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Hamartomas of the Breast: A Mimic of Fibroadenoma and Cytological Pitfall.

J Cytol 2020 Oct-Dec;37(4):210-211. Epub 2020 Oct 31.

Department of Cytopathology, PGIMER, ABVIMS, RML Hospital, New Delhi, India.

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October 2020

Retrospective study of malignant phyllodes tumors of the breast: Younger age, prior fibroadenoma surgery, malignant heterologous elements and surgical margins may predict recurrence.

Breast 2021 Jun 17;57:62-70. Epub 2021 Mar 17.

Department of Radiation Oncology, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin, China. Electronic address:

Purpose: The potential recurrence rate of malignant phyllodes tumors (MPTs) of the breast is high, and the prognostic factors are still unclear. We therefore aim to study the factors affecting the outcome of MPTs.

Methods: A retrospective review of MPT patients treated from 2006 to 2020 at our institution was conducted. Read More

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Sliding window based deep ensemble system for breast cancer classification.

J Med Eng Technol 2021 Mar 26:1-11. Epub 2021 Mar 26.

Department of Biomedical Systems and Informatics Engineering, Hijjawi Faculty for Engineering Technology, Yarmouk University, Irbid, Jordan.

Breast cancer is a severe problem for women around the world especially in developing countries, according to recent reports from the World Health Organization (WHO). High accuracy and early detection of breast cancer reduces the mortality rate, in the other hand, recognition of breast cancer is a complicated issue. Various studies and methods have been carried out to overcome this problem and to obtain accurate screening of breast cancer. Read More

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An atypically located pleomorphic adenoma: Radiological and pathological correlation.

J Med Imaging Radiat Oncol 2021 Mar 25. Epub 2021 Mar 25.

Department of Radiology, Royal Perth Hospital, Perth, Western Australia, Australia.

Pleomorphic adenoma is a common benign salivary gland neoplasm which very rarely occurs in the breast. Its radiologic and pathologic appearance may be mistaken for other benign or malignant lesions such as a fibroadenoma or invasive ductal carcinoma. Due to the risk of local recurrence and, rarely, malignant transformation, wide local excision with clear margins is recommended. Read More

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A Study of Anxiety and Depression in Benign Breast Disease.

J Midlife Health 2020 Oct-Dec;11(4):200-209. Epub 2021 Jan 21.

Department of General Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.

Background: To compare the prevalence of anxiety and depression levels in patients with benign breast disease (BBD) and healthy individuals using Hospital Anxiety and Depression Scale (HADS) and Brief Patient Health Questionnaire (BPHQ).

Methods: This study includes 100 patients who were clinically suspected of having BBDs and were matched against 100 healthy age-matched controls from June 2016 and July 2018. The diagnosis of BBD was established on the basis of ultrasonography, fine needle aspiration cytology, and/or histopathology. Read More

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January 2021

[The HRT follow-up consultation. What to do in case of breast tumour (clinical or radiological) and microcalcifications. Postmenopausal women management: CNGOF and GEMVi clinical practice guidelines].

Gynecol Obstet Fertil Senol 2021 May 20;49(5):485-492. Epub 2021 Mar 20.

CHRU, Hôpitaux universitaires de Strasbourg, 1, place de l'hôpital, 67091 Strasbourg, France; Unité d'imagerie mammaire, Institut de cancérologie Strasbourg Europe (ICANS), 17, rue Albert-Calmette. 67033 Strasbourg cedex, France.

Objective: The objective was to evaluate the diagnostic value of clinical examination and complementary imaging in the exploration of a breast lump or microcalcifications occurring in a postmenopausal woman taking hormonal replacement therapy (HRT), based on a systematic review of the literature in order to make recommendations for HRT management.

Methods: A literature review was conducted using Medline, Cochrane Library data and international recommendations in French and English until 2020.

Results: In the presence of a clinical breast mass in postmenopausal women, there is no clinical evidence to rule out cancer. Read More

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Giant Juvenile Fibroadenoma of the breast in a 13-year-old Pakistani girl with excellent cosmetic outcome after subareolar enucleation - A case report.

Int J Surg Case Rep 2021 Feb 28;79:450-454. Epub 2021 Jan 28.

Section of Breast Surgery, Department of Surgery, The Aga Khan University, P.O. Box 3500, Stadium Road, Karachi, 74800, Pakistan. Electronic address:

Introduction: Fibroadenoma is the most common benign lesion of breast in young women, characterized by an aberrant proliferation of both epithelial and mesenchymal elements. It is termed giant fibroadenoma when it is larger than 5 cm or weighs more than 500 g with an incidence of 0.5-2% of all fibroadenomas. Read More

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February 2021

Quantitative proteome profiling stratifies fibroepithelial lesions of the breast.

Oncotarget 2021 Mar 2;12(5):507-518. Epub 2021 Mar 2.

Cancer Biology, CSIR-Centre for Cellular and Molecular Biology, Hyderabad, Telangana, 500007, India.

Breast fibroepithelial lesions (FELs) include heterogeneous pathological tumors, involving indolent fibroadenoma (FAD) to potentially aggressive phyllodes tumors (PTs). The current grading system remains unreliable in differentiating these tumors due to histological heterogeneity and lack of appropriate markers to monitor the sudden and unpredictable malignant transformation of PTs. Thus, there exists an imminent need for a marker-based diagnostic approach to augment the conventional histological platform that could lead to accurate diagnosis and distinction of FELs. Read More

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Feasibility and efficacy of microwave ablation for treating breast fibroadenoma.

Int J Hyperthermia 2021 ;38(1):471-478

Department of Breast Surgery, The Third Hospital of Nanchang City, Key Laboratory of Breast Diseases, Nanchang, China.

Background: To investigate the safety, efficacy, and follow-up outcomes of microwave ablation (MWA) in patients with breast fibroadenoma.

Methods: An institutional review board-approved this study of patients treated with MWA for breast fibroadenoma from October 2017 to March 2019. Clinical features of patients and breast fibroadenoma were analyzed. Read More

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January 2021

Breast fibroadenomas: a review in the light of current literature.

Pol Przegl Chir 2020 Dec;93(1):40-48

Unaizah College of Medicine, Qassim University, Kingdom of Saudi Arabia.

<br><b>Introduction:</b> Fibroadenomas are one of the most common benign tumors of the breast in the adolescent females accounting for about 2/3<sup>rd</sup> of all the breast lumps and more than half of all the biopsied breast lesions. They come into being due to overgrowth of glandular tissue under the influence of hormonal changes that the girls undergo at the time of puberty. Due to the wide prevalence of fibroadenomas and the psychosocial morbidity associated with the finding of a breast mass, it is imperative for physicians treating adolescent patients to be thoroughly familiar and updated with this disease. Read More

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December 2020

The efficacy and safety of indocyanine green-hyaluronic acid mixture (LuminoMark™) for localization in patients with non-palpable breast lesions: a multi-center open-label parallel phase-2 clinical trial.

BMC Surg 2021 Mar 16;21(1):134. Epub 2021 Mar 16.

Division of Breast Surgery, Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.

Background: Increasing rates of breast cancer screening have been associated with an increasing frequency of non-palpable breast lesions detection. Preoperative breast lesion localization is essential for optimizing excision accuracy. This study aimed to evaluate the efficacy and safety of indocyanine green (ICG) hyaluronic acid injection as a novel mixture for localization. Read More

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Low-grade ductal carcinoma in situ (DCIS) arising in a fibroadenoma of the breast during 5 years follow-up: A case report.

Medicine (Baltimore) 2021 Mar;100(10):e24023

Department of Radiology, University of Toyama.

Rationale: Fibroadenoma (FA) is a common type of benign breast tumors but ductal carcinoma in situ (DCIS) rarely arises within this tumor type.

Patient Concerns: This case report presents a non-symptomatic 61-year-old woman with FA that was coincidentally found during a breast cancer screening program performed 5 years ago by her city of residence. She had subsequently been followed-up with mammography and breast ultrasound (US). Read More

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Primary stromal sarcoma of breast: A case report and literature review.

Breast Dis 2021 Mar 9. Epub 2021 Mar 9.

Department of General and Special Surgery, Faculty of Medicine, Hashemite University, Zarqa, Jordan.

Introduction: Primary breast sarcoma (PBS) was first described in 1887 as a rare heterogeneous neoplasm arising from the mesenchymal tissue of the mammary gland accounting for less than 5% of all body soft-tissue sarcomas and less than 0.1% of all malignant tumors of the breast.

Case Presentation: A 31-year old lady presented with left breast mass which she felt four years before during which the mass increased in size from 1 to 6 cm in the largest diameter, diagnosed clinically as a benign fibroadenoma without any further cytological or histopathological confirmation. Read More

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Clinicopathological significance of immunohistochemical expression of Filamin A in breast cancer.

J Carcinog 2020 5;19:13. Epub 2020 Dec 5.

Department of Surgery, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.

Background: Filamin A is an actin-crosslinking protein expressed in many malignancies, although its prognostic and therapeutic role in breast cancer is not studied. There is enigma regarding its dual role in cancer, the tumor-progressing or tumor-suppressing effects depending on the site to which it localizes in the cell. The current study aimed to detect Filamin A expression in breast cancer and its association with other biomarkers and other clinicopathological parameters and established risk factors in breast cancer so that it can be a potential site for targeted therapy. Read More

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December 2020

Gene expression profiling of giant fibroadenomas of the breast.

Surg Oncol 2021 Mar 2;37:101536. Epub 2021 Mar 2.

Center for Cancer and Stem Cell Research, Institute for Research, Development and Innovation (IRDI), International Medical University, Kuala Lumpur, Malaysia; School of Pharmacy, International Medical University, Kuala Lumpur, Malaysia. Electronic address:

Introduction: Fibroadenomas of the breast present as two phenotypic variants. The usual variety is 5 cm or less in diameter and there is another large variant called giant fibroadenoma which is greater than 5 cm in diameter. Despite of its large size, it is not malignant. Read More

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Serum Long Non-Coding RNAs PVT1, HOTAIR, and NEAT1 as Potential Biomarkers in Egyptian Women with Breast Cancer.

Biomolecules 2021 02 18;11(2). Epub 2021 Feb 18.

Biochemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Einy Street, Cairo 11562, Egypt.

Long non-coding RNAs play an important role in tumor growth, angiogenesis, and metastasis in several types of cancer. However, the clinical significance of using lncRNAs as biomarkers for breast cancer diagnosis and prognosis is still poorly investigated. In this study, we analyzed the serum expression levels of lncRNAs PVT1, HOTAIR, NEAT1, and MALAT1, and their associated proteins, PAI-1, and OPN, in breast cancer patients compared to fibroadenoma patients and healthy subjects. Read More

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February 2021

Interleukin-18 and -10 may be associated with lymph node metastasis in breast cancer.

Teng Ma Meng Kong

Oncol Lett 2021 Apr 3;21(4):253. Epub 2021 Feb 3.

Department of General Surgery, Qilu Children's Hospital of Shandong University, Jinan, Shandong 250022, P.R. China.

Reports on the expression of interleukin (IL)-10 in breast cancer are rare. The present study investigated the correlation between IL-18 and -10 in breast cancer, and assessed their clinical significance. Breast cancer (n=104) and breast fibroadenoma (n=31) tissues that were surgically removed and pathologically confirmed at Jinan Central Hospital Affiliated to Shandong University (Jinan, China) between November 2016 and January 2019 were collected. Read More

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Organochlorine Pesticide Tissue Levels in Benign and Malignant Breast Disease: A Comparative Exploratory Study.

J Environ Pathol Toxicol Oncol 2021 ;40(1):43-50

Department of Surgery, University College of Medical Sciences and Guru Teg Bahadur Hospital, University of Delhi, India.

Exposure to organochlorine pesticides (OCPs) may be a risk factor for breast cancer (BC). Their role may be more relevant in developing countries such as India, where an abundance of these products is used for agricultural purposes. The present study compares OCP tissue levels in patients who underwent BC surgery (group A) or patients who had surgery for excision of breast fibroadenoma (group B). Read More

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Fatal outcome of malignant phyllodes tumor of the breast in pregnancy: a case and literature review.

Gland Surg 2021 Jan;10(1):371-377

Department of Breast Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Phyllodes tumor of the breast (PTB) is a rare fibroepithelial breast neoplasm that accounts for less than 1% of breast tumors. Only a few cases related to pregnancy have been reported. It is not known how pregnancy affects the diagnosis, treatment and prognosis of breast tumors. Read More

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January 2021

Reactive eccrine syringofibroadenoma triggered by thermal damage: case report.

An Bras Dermatol 2021 Mar-Apr;96(2):255-256. Epub 2021 Jan 25.

Department of Basic Pathology, Biological Sciences Sector, Universidade Federal do Paraná, Curitiba, PR, Brazil.

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Prospective clinical trial on high-intensity focused ultrasound for the treatment of breast fibroadenoma.

Breast J 2021 Mar 15;27(3):294-296. Epub 2021 Feb 15.

Bristol Medical School, University of Bristol, Bristol, UK.

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