Toxicology 2021 Apr 5;456:152771. Epub 2021 Apr 5.
Technische Universität Dresden, School of Science, Faculty of Biology, Institute of Zoology, Chair of Molecular Cell Physiology and Endocrinology, Zellescher Weg 20b, 01217, Dresden, Germany. Electronic address:
Lanthanide (Ln) exposure poses a serious health risk to animals and humans. In this study, we investigated the effect of 10-10 M La, Ce, Eu, and Yb exposure onto the viability of rat renal NRK-52E cells in dependence on Ln concentration, exposure time, and composition of the cell culture medium. Especially, the influence of fetal bovine serum (FBS) and citrate onto Ln cytotoxicity, solubility, and speciation was investigated. Read More