Biosens Bioelectron 2021 Jan 12;171:112721. Epub 2020 Oct 12.
Department of Chemical and Environmental Engineering, University of California, Riverside, Riverside, CA, 92521, USA; Center for Environmental Research and Technology (CE-CERT), University of California, Riverside, Riverside, CA, 92507, USA. Electronic address:
We developed an affordable, highly sensitive, and specific paper-based microfluidic platform for fast multiplexed detections of important biomarkers in various body fluids, including urine, saliva, serum, and whole blood. The sensor array consisted of five individual sensing channels with various functionalities that only required a micro liter-sized sample, which was equally split into aliquots by the built-in paper microfluidics. We achieved the individual functionalizations of various bioreceptors by employing the use of wax barriers and 'paper bridges' in an easy and low-cost manner. Read More