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Cross-Sectional Analysis of Quality of Life in Pediatric Patients with Inflammatory Bowel Disease in British Columbia, Canada.

J Pediatr 2021 Jul 19. Epub 2021 Jul 19.

Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Faculty of Medicine, British Columbia Children's Hospital, University of British Columbia, B.C., Canada; British Columbia Children Hospital Research Institute, Vancouver, British Columbia, Canada; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, B.C., Canada. Electronic address:

Objectives: To evaluate Quality of Life (QoL) in a large cohort of pediatric patients with Inflammatory Bowel Disease (IBD) and to identify the clinical factors that influence QoL.

Study Design: This cross-sectional study analyzes a quality improvement initiative in 351 pediatric patients with IBD in British Columbia, Canada using the self-reported PedsQL 4.0 generic scale. Read More

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Attachment Style Mediates the Relationship between Trauma and Somatic Distress among Individuals with Serious Mental Illness.

Psychiatry 2021 ;84(2):150-164

: Individuals with mental illnesses severe enough to require psychiatric hospitalization often have significant trauma histories, have developed maladaptive attachment styles, and experience comorbid somatic distress. Gaining an understanding about the interaction of such factors may lead to prioritizing interventions that target factors that mediate the relationship between trauma and adverse somatic distress. Prior research has examined various mediation models, but results have been mixed and conducted only on outpatient samples. Read More

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January 2021

Prevalence of hyperventilation in patients with asthma.

J Asthma 2021 Jul 22:1-11. Epub 2021 Jul 22.

Radboud university medical center, Radboud Institute for Health Sciences, Department of Respiratory Diseases, 6525 GA Nijmegen, The Netherlands.

Objective: Asthma is frequently accompanied by dysfunctional breathing of which hyperventilation has been recognized as a subtype. The prevalence of hyperventilation in stable asthma has been scantily studied using blood gas analysis. Hence, a reliable estimate of its prevalence is lacking. Read More

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Longitudinal analysis of client appointment adherence under Universal Test and Treat strategy: A stepped-wedge trial.

HIV Med 2021 Jul 22. Epub 2021 Jul 22.

Harvard T.H. Chan School of Public Health, Boston, MA, USA.

Objectives: Universal Test and Treat (UTT) strategies are being adopted across sub-Saharan Africa based on clinical benefits to morbidity and mortality and to attain targets of the Joint United Nations Programme on HIV/AIDS (UNAIDS). Universal Test and Treat is expected to change the client population at clinics, due to more asymptomatic HIV clients initiating antiretroviral therapy (ART). We assessed the impact of UTT on client appointment adherence at 14 government-managed health facilities in Eswatini's public sector health system. Read More

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Transcondylar Odontoid Resection and Stabilization for Craniovertebral Degenerative Compression: 2-Dimensional Operative Video.

Oper Neurosurg (Hagerstown) 2021 Jul 22. Epub 2021 Jul 22.

Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Non-neoplastic craniovertebral junction lesions are well known with various etiologies.1,2 They are frequently associated with craniovertebral junction instability. Many require only stabilization for their management. Read More

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Male microchimerism in females: a quantitative study of twin pedigrees to investigate mechanisms.

Hum Reprod 2021 Jul 19. Epub 2021 Jul 19.

Amsterdam Reproduction and Development (AR&D) Research Institute, Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands.

Study Question: Does having a male co-twin, older brothers, or sons lead to an increased probability of persistent male microchimerism in female members of twin pedigrees?

Summary Answer: The presence of a male co-twin did not increase risk of male microchimerism and the prevalence of male microchimerism was not explained by having male offspring or by having an older brother.

What Is Known Already: Microchimerism describes the presence of cells within an organism that originate from another zygote and is commonly described as resulting from pregnancy in placental mammals. It is associated with diseases with a female predilection including autoimmune diseases and pregnancy-related complications. Read More

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Population-based utility scores for HPV infection and cervical squamous cell carcinoma among Australian Indigenous women.

PLoS One 2021 22;16(7):e0254575. Epub 2021 Jul 22.

Adelaide Dental School, Australian Research Centre for Population Oral Health, The University of Adelaide, Adelaide, Australia.

Objective: Working in partnership with Indigenous communities in South Australia, we aimed to develop, pilot test and estimate utility scores for health states relating to cervical cancer screening, precancer, and invasive cervical cancer and precancer/cancer treatment among Indigenous women.

Methods: Development and pilot testing of hypothetical cervical cancer health states, specifically through the lens of being an Indigenous Australian woman, was done with an Indigenous Reference Group in conjunction with five female Indigenous community members. Six health states were developed. Read More

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Decreases in psychiatric symptoms persist following exposure-based group therapy for sexual violence victimization among incarcerated women.

Psychol Serv 2021 Jul 22. Epub 2021 Jul 22.

Department of Psychological Science.

(SHARE) is a brief, exposure-based group treatment for incarcerated female survivors of sexual violence. Preliminary evaluations of SHARE showed declines in depression and posttraumatic stress disorder (PTSD) symptoms from pre- to posttreatment. However, prior investigations have not included a longitudinal follow-up period and thus knowledge of whether therapeutic benefits persist following the termination of the group is lacking. Read More

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Ethnic and national identity development processes: The role of cultural behaviors and gender.

Cultur Divers Ethnic Minor Psychol 2021 Jul 22. Epub 2021 Jul 22.

Department of Sociology, University of Victoria.

This study examined the interrelations between Chinese and Canadian identity development during adolescence over an 18-month period using an individual-in-context perspective. We simultaneously considered the roles of youths' cultural behavior practices and their gender for predicting identity processes. We also examined whether practicing heritage cultural behaviors interferes with or is unrelated to national identity development and vice versa. Read More

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Surgical oncology operative experience at a high-volume safety-net hospital during the COVID-19 pandemic.

J Surg Oncol 2021 Jul 22. Epub 2021 Jul 22.

Division of Surgical Oncology, Department of Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA.

Background: The coronavirus (COVID-19) pandemic led to disruptions in operative and hospital capabilities as the country triaged resources and canceled elective procedures. This study details the operative experience of a safety-net hospital for cancer-related operations during a 3-month period at the height of the pandemic.

Methods: Patients operated on for or diagnosed with malignancies of the abdomen, breast, skin, or soft-tissue (September 3, 2020-September 6, 2020) were identified from operative/clinic schedules. Read More

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Characterization of American Teduglutide Consumers from 2015-2020: A Large Database Study.

JPEN J Parenter Enteral Nutr 2021 Jul 21. Epub 2021 Jul 21.

Louis Stokes VA Medical Center, Cleveland, Ohio, United States.

Introduction: Teduglutide, a glucagon-like peptide-2 analog, is a novel therapy for intestinal failure that reduces need for parenteral support, especially in patients without a functional terminal ileum or colon. It can also predispose patients to accelerated progression of gastrointestinal malignancy and fluid overload. We demographically and clinically characterized American patients prescribed teduglutide using a large database. Read More

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Ruptured Renal Abscess From Streptococcus agalactiae Invasion in a Postpartum Female.

Cureus 2021 Jun 16;13(6):e15701. Epub 2021 Jun 16.

Internal Medicine, Wright State University Boonshoft School of Medicine, Dayton, USA.

(Group B or GBS)is an exceptionally rare causative organism of a ruptured renal abscess. We report a case of this normally commensal organism causing a large ruptured renal abscess in a 17-year-old postpartum female. Although is known to cause postpartum neonatal morbidity and mortality, it has rarely caused invasive infections in the last 20 years in adults. Read More

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Cohort profile: an observational longitudinal data collection of health aspects in a cohort of female cancer survivors with a history of pelvic radiotherapy-a population-based cohort in the western region of Sweden.

BMJ Open 2021 Jul 21;11(7):e049479. Epub 2021 Jul 21.

Division of Clinical Cancer Epidemiology, Department of Oncology, Institute of Clinical Science, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Purpose: The study 'Health among women after pelvic radiotherapy' was conducted in response to the need for more advanced and longitudinal data concerning long-term radiotherapy-induced late effects and chronic states among female cancer survivors. The objective of this paper is to detail the cohort profile and the study procedure in order to provide a sound basis for future analyses of the study cohort.

Participants: Since 2011, and still currently ongoing, participants have been recruited from a population-based study cohort including all female patients with cancer, over 18 years of age, treated with pelvic radiotherapy with curative intent at Sahlgrenska University Hospital in Gothenburg, in the western region of Sweden, which covers 1. Read More

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Promoting proactive bystander responses to racism and racial discrimination in primary schools: a mixed methods evaluation of the 'Speak Out Against Racism' program pilot.

BMC Public Health 2021 Jul 21;21(1):1434. Epub 2021 Jul 21.

Centre for Health Equity, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia.

Background: Racism and racial discrimination are fundamental causes and determinants of health and health inequalities globally, with children and adolescents particularly vulnerable. Racial discrimination is a common stressor in the lives of many children and adolescents, with growing evidence of negative associations between racial discrimination and multiple domains of child and adolescent health. Addressing racism and racial discrimination must be core public health priorities, even more so among children and young people. Read More

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Sense of Coherence and COVID-19: A Longitudinal Study.

J Psychol 2021 Jul 21:1-21. Epub 2021 Jul 21.

Family Studies and Research University Centre, Università Cattolica del Sacro Cuore.

The strong restrictive measures adopted in 2020 against the spread of the COVID-19 pandemic in Italy have deeply affected the general population's mental health. In the current longitudinal study, we specifically focus on sense of coherence (SOC), both in terms of comprehensibility/manageability and meaningfulness, among a large sample of Italian adults; SOC is a potential resource likely to foster the ability to cope with stressors. A total of 2,191 Italian participants (65. Read More

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The Impact of Surgical Center Volume on Reoperation Risk After Midurethral Sling.

J Urol 2021 Jul 21:101097JU0000000000002140. Epub 2021 Jul 21.

Division of Female Pelvic Medicine and Reconstructive Surgery, Department of OB/GYN, Kaiser Permanente, San Diego, California.

Objective: To determine whether a center's surgical volume affects patient reoperation rates after midurethral sling surgery.

Methods: We performed a retrospective cohort study evaluating a large managed care organization from 2005 to 2016. The primary outcome was the MUS reoperation rate. Read More

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Pitfalls in Diagnosing Urinary Tract Infection in Children Below the Age of 2. Suprapubic Aspiration Vs. Clean Catch Urine Sampling.

J Urol 2021 Jul 21:101097JU0000000000002117. Epub 2021 Jul 21.

Department of Paediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark.

Purpose: Reliable urine samples are of eminent importance when diagnosing urinary tract infections (UTI) in children. Non-invasive procedures are convenient, but likely to be contaminated. This study aimed to compare the diagnostic accuracy of urine samples obtained by the midstream clean-catch method (CCU) with urine obtained by suprapubic aspiration (SPA), and evaluate the ability of urinary dipstick to predict true infection. Read More

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Sex differences in sensory processing in children with autism spectrum disorder.

Autism Res 2021 Jul 20. Epub 2021 Jul 20.

Service des Troubles du Spectre de l'Autisme et apparentés, Lausanne University Hospital, Lausanne, Switzerland.

Despite the high prevalence of sensory processing difficulties in children with autism spectrum disorder (ASD), little research has focused on the sex differences in sensory processing. Furthermore, there is a lack of knowledge on the female-specific symptoms of ASD, contributing to later referral, diagnosis and intervention. In this study, we examined the sex differences in sensory processing symptoms in large cohorts of ASD children (N = 168; 26 females, 142 males) and typically developing (TD) children (N = 439; 209 females, 230 males). Read More

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A new 2D-3D registration gold-standard dataset for the hip joint based on uncertainty modeling.

Med Phys 2021 Jul 21. Epub 2021 Jul 21.

Geneva School of Health Sciences, University of Applied Sciences and Arts of Western Switzerland (HES-SO), Geneva, 1206, Switzerland.

Purpose: Estimation of the accuracy of 2D-3D registration is paramount for a correct evaluation of its outcome in both research and clinical studies. Publicly available datasets with standardized evaluation methodology are necessary for validation and comparison of 2D-3D registration techniques. Given the large use of 2D-3D registration in biomechanics, we introduced the first gold standard validation dataset for Computed Tomography (CT)-to-X-ray registration of the hip joint, based on fluoroscopic images with large rotation angles. Read More

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Outcomes of redo-transversus abdominis release for abdominal wall reconstruction.

Hernia 2021 Jul 21. Epub 2021 Jul 21.

Department of General Surgery, Cleveland Clinic Center for Abdominal Core Health, Digestive Disease and Surgery Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, A100, A10-133, Cleveland, OH, 44195, US.

Background: Transversus abdominis release (TAR) is increasingly used to address complex ventral hernias; consequently, associated complications are seen more frequently. Our hernia center has a growing experience with redo-transversus abdominis release (redo-TAR) to address large, complex hernia recurrences after failed TAR. Here, we describe our outcomes after abdominal wall reconstruction with redo-TAR. Read More

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Relationship of the type of breastfeeding in the sexual function of women.

Rev Lat Am Enfermagem 2021 19;29:e3438. Epub 2021 Jul 19.

Universidade de São Paulo, Escola de Enfermagem de Ribeirão Preto, PAHO/WHO Collaborating Centre for Nursing Research Development, Ribeirão Preto, SP, Brazil.

Objective: to relate the type of breastfeeding in the women's sexual function.

Method: a cross-sectional study conducted with 150 women in the postpartum period registered in the Family Health Strategy of a large Brazilian municipality. Two instruments were used: one for characterizing sociodemographic, obstetric and breastfeeding variables, and the Female Sexual Function Index for the sexual function. Read More

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Electroencephalography Patterns of Subacute Sclerosing Panencephalitis.

Cureus 2021 Jun 17;13(6):e15728. Epub 2021 Jun 17.

Internal Medicine, Khyber Teaching Hospital, Peshawar, PAK.

Introduction And Background: This article explores the electroencephalography (EEG) pattern in patients of suspected subacute sclerosing panencephalitis (SSPE) visiting Lady Reading Hospital, Peshawar. Pakistan has a huge deficit of research culture, and limited studies are done on this topic. This study concluded that a typical pattern is the most common EEG pattern, although atypical and normal EEG patterns were also observed. Read More

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Juvenile granulosa cell tumor diagnosed in 6-month-old infant with precocious puberty.

Radiol Case Rep 2021 Sep 10;16(9):2609-2613. Epub 2021 Jul 10.

Department of Radiology, Medical University of South Carolina, Charleston, SC, USA.

Juvenile granulosa cell tumor is a rare tumor diagnosed in children, which can present with precocious puberty. We have reported a case of a 6-month-old female patient who presented with precocious puberty. Abdominopelvic imaging revealed a large mixed cystic and solid mass, with internal solid enhancement, and restricted diffusion. Read More

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September 2021


Acta Clin Croat 2020 Dec;59(4):582-589

1Division of Perinatology, Istanbul Medeniyet University, Faculty of Medicine, Istanbul, Turkey; 2Division of Genetic Disease, Van Regional Training and Research Hospital, Van, Turkey; 3Division of Obstetrics & Gynecology, Van Regional Trainingand Research Hospital, Van, Turkey; 4Bahceci Infertility and IVF Center, Fulya, Istanbul, Turkey.

The objective of this study was to evaluate the association between aberrant right subclavian artery (ARSA) and chromosomal abnormalities. The study included 5211 women having attended our unit for fetal anatomic screening and fetal echocardiography from August 2016 until February 2019. After diagnosing ARSA, prenatal invasive testing was discussed with the patients. Read More

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December 2020

N-glycosylation of immunoglobulin G predicts incident hypertension.

J Hypertens 2021 Jul 19. Epub 2021 Jul 19.

Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia Department of Twin Research, Kings College London, London, UK Genos Glycoscience Research Laboratory, Zagreb, Croatia Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München Research Center for Environmental Health German Center for Diabetes Research (DZD) Institute of Epidemiology, Helmholtz Zentrum München Research Center for Environmental Health LMU Munich, IBE-Chair of Epidemiology, Neuherberg, Germany Department of Public Health, University of Split, School of Medicine, Split, Croatia NIHR Biomedical Research Centre at Guy's and St Thomas' Foundation Trust, London Academic Rheumatology Clinical Sciences Building, Nottingham City Hospital, University of Nottingham, Nottingham University of Glasgow, Glasgow, Scotland, UK.

Objectives: Glycosylation of immunoglobulin G (IgG) is an important regulator of the immune system and has been implicated in prevalent hypertension.The aim of this study is to investigate whether the IgG glycome begins to change prior to hypertension diagnosis by analysing the IgG glycome composition in a large population-based female cohort with two independent replication samples.

Methods: We included 989 unrelated cases with incident hypertension and 1628 controls from the TwinsUK cohort (mean follow-up time of 6. Read More

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Arterial hypertension as an inaugural sign of myomatous uterus.

BMJ Case Rep 2021 Jul 20;14(7). Epub 2021 Jul 20.

Department of Gynecology, Centro Hospitalar e Universitario de Coimbra EPE, Coimbra, Portugal.

Uterine fibroids can be large enough to cause mechanical obstruction of pelvic ureters, which may result in hydroureters and hydronephrosis. Renal impairment frequently results in hypertension due to increased activity of the tubuloglomerular feedback system and renin-angiotensin-aldosterone axis. This process, however, seems reversible because normalisation of blood pressure is possible after the relief of renal obstruction. Read More

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Development of a BMI-Assigned Stunkard Scale for the Evaluation of Body Image Perception Based on Data of the SOS Reference Study.

Obes Facts 2021 Jul 20:1-8. Epub 2021 Jul 20.

Institute of Medicine, Department of Molecular and Clinical Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.

Introduction: Stunkard's figure rating scale is a widely used tool to assess weight status and, more recently, body image perception in people with obesity. However, large population-based studies on Europeans linking this scale's silhouettes with measured BMI values are lacking. Therefore, we used measured weight and height data from the Swedish Obese Subjects (SOS) reference cohort to assign a mean BMI to each of the 9 Stunkard Scale silhouettes and to define silhouette cutoff values for categorizing people with obesity and overweight. Read More

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Knowledge and awareness of COVID-19 among Indonesian migrant workers in the Greater China Region.

Public Health 2021 Jun 12;197:28-35. Epub 2021 Jun 12.

Department of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; New York University (Shanghai), Shanghai, PR China. Electronic address:

Objectives: Migrant workers are one of the most vulnerable population groups during the coronavirus disease 2019 (COVID-19) pandemic. This study investigated knowledge and awareness of COVID-19 among Indonesian migrant workers (IMWs) in Macao (SAR), Hong Kong (SAR), and Taiwan.

Study Design: This was a cross-sectional study. Read More

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Visual outcomes in idiopathic intracranial hypertension in children.

Can J Ophthalmol 2021 Jul 17. Epub 2021 Jul 17.

Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ont.; Department of Ophthalmology and Vision Sciences, Hospital for Sick Children, Toronto, Ont.. Electronic address:

Objective: The purpose of this study was to report the clinical characteristics and long-term visual outcomes in a cohort of children with idiopathic intracranial hypertension (IIH).

Design: Retrospective, observational cohort study.

Participants: Consecutive children who met the diagnostic criteria for definite IIH at a tertiary care pediatric hospital between 2009 and 2020. Read More

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[A prognosis scale for functional outcome at discharge after endovascular thrombectomy in the carotid artery territory].

Zh Nevrol Psikhiatr Im S S Korsakova 2021 ;121(6):34-39

City Multi-Field Hospital «Elizavetinskaya bolnitsa», St. Petersburg, Russia.

Objective: To develop a method for early (24 hrs after intervention) prognosis of functional outcome at discharge in patients after endovascular thrombectomy (EVT) in anterior cerebral circulation based on NIHSS.

Material And Methods: A retrospective analysis of endovascular treatment in 362 acute stroke patients (189 men, 173 women, median age 69 years) with anterior circulation large vessel occlusion was performed in the regional vascular centers of St. Petersburg. Read More

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