- Markus J Ege
Ann Am Thorac Soc 2017 Nov;14(Supplement_5):S348-S353
Dr. von Hauner Children's Hospital, Ludwig Maximilians University Munich and Comprehensive Pneumology Centre Munich, German Centre for Lung Research, Munich, Germany.
The original version of the hygiene hypothesis suggested that infections transmitted early in life by "unhygienic contact" prevented allergies. Examples were endemic fecal-oral infections by viral, bacterial, or protozoic pathogens, such as hepatitis A virus, Helicobacter pylori, or Toxoplasma gondii. Later, this concept also included microorganisms beyond pathogens, such as commensals and symbionts, and the hygiene hypothesis was extended to inflammatory diseases in general. Read More