Arterioscler Thromb Vasc Biol 2021 Apr 29:ATVBAHA120315698. Epub 2021 Apr 29.
Department of Cardiology and Angiology, University Hospital Tuebingen, Eberhard Karls University Tuebingen, Germany. (C.L., A.-K.R., S.G., Á.P.-U., P.J., A.A., T.H., K.-P.K., T.C., D.R., M.P.G., K.A.L.M.).
Objective: Patients with coronary artery disease (CAD) are at increased risk for cardiac death and respiratory failure following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Platelets are crucially involved in pathogenesis of CAD and might also contribute to pathophysiology of SARS-CoV-2 infection. Approach and Results: We enrolled a cohort of 122 participants from February 2020 to July 2020 including 55 patients with preexisting CAD and acute SARS-CoV-2 infection (CAD-SARS-CoV-2), 28 patients with CAD and without SARS-CoV-2 (CAD-SARS-CoV-2), and 39 healthy controls. Read More