Am J Surg Pathol 2021 Sep 13. Epub 2021 Sep 13.
Department of Pathology, Charles University, Faculty of Medicine in Plzen Bioptic Laboratory Ltd Molecular and Genetic Laboratory, Bioptic Laboratory Ltd, Plzen The Fingerland Department of Pathology, Charles University, Faculty of Medicine and University Hospital Hradec Kralove, Hradec Králové Department of Pathology and Molecular Medicine, 2nd Faculty of Medicine in Prague, Prague, Charles University and Motol University Hospital, Prague, Czech Republic Department of Histopathology, Division of Clinical Medicine, University of Surrey, Royal Surrey County Hospital, Guildford, Surrey, UK Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Comprehensive Cancer Center (CCC) Erlangen-EMN, Erlangen, Germany Department of Pathology, CHU Gui de Chauliac, Montpellier, France Department of Pathology, National University Health System, Singapore, Singapore Department of Pathology, Research Institute GROW, Maastricht University Medical Center, Maastricht, The Netherlands Department of Anatomic Histopathology and Cytogenetics, Department of Laboratory Medicine, Niguarda Cancer Center, Milan, Italy Medical Laboratory CSD, Kyiv, Ukraine Institute of Biomedicine, Pathology, University of Turku, and Turku University Hospital, Turku, Finland.
Sclerosing polycystic adenoma (SPA) is a rare salivary gland neoplasm originally thought to represent a non-neoplastic lesion. Recently we have encountered an index case of apocrine intraductal carcinoma of parotid gland of 62-year-old man with invasive salivary duct carcinoma component arising from SPA, a combination of tumor entities that has never been published so far. Here, we further explore the nature of SPA by evaluating 36 cases that were identified from the authors' consultation files. Read More