6,614 results match your criteria feasibility reliability


Tools to study the severity of itch in 8- to 17-year-old children: Validation of TweenItchyQoL and ItchyQuant.

Pediatr Dermatol 2021 Aug 2. Epub 2021 Aug 2.

Duke University School of Medicine, Durham, NC, USA.

Background/objectives: Validated pruritus-specific quality of life and self-reported severity instruments exist primarily for adults. Clinical trials to develop therapeutics for children with chronic pruritus are hampered by the paucity of appropriate outcome measures. To address this gap, we aimed to develop validated instruments to measure itch-specific quality of life and self-reported severity in children. Read More

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Development and validation of a patient-reported outcome measure for patients with chronic respiratory failure: The CRF-PROM scale.

Health Expect 2021 Aug 1. Epub 2021 Aug 1.

Department of Health Statistics, Shanxi Medical University, Taiyuan, Shanxi Province, China.

Background: Various health-related quality-of-life (HRQOL) tools are used to evaluate patients with chronic respiratory failure (CRF), but there is a relative lack of tools available for the evaluation of social support and treatment in these patients. The present study focused on the development of a systematic patient-reported outcome measure (PROM) tool for use in patients with CRF.

Methods: The CRF-PROM scale conceptual framework and item bank were generated after reviewing the corresponding literature and HRQOL scales, interviewing CRF patients and focus groups. Read More

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Revisiting pedicled latissimus dorsi flaps in head and neck reconstruction: contrasting shoulder morbidities across mysofascial flaps.

Plast Aesthet Res 2021 25;8. Epub 2021 Feb 25.

Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, MI 48109, USA.

Free tissue transfer has become the gold standard for reconstruction within the head and neck. However, there are still many instances where pedicled locoregional flaps are the optimal reconstructive option. When myofascial tissue is needed, several options have been described throughout the literature. Read More

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February 2021

Reliability and validity of clinically useful depression outcome scale identifying mixed features in patients with manic episode.

Brain Behav 2021 Aug 1. Epub 2021 Aug 1.

Hongkou District Mental Health Center, Shanghai, P. R. China.

Objectives: This study aims to explore the reliability, validity, and feasibility of Clinically Useful Depression Outcome Scale (CUDOS) in screening mixed features in patients diagnosed with mania.

Methods: A total of 109 patients with (hypo-) manic episode were recruited. The reliability of Chinese version of CUDOS (CUDOS-C) were analyzed with Cronbach's alpha and intraclass correlation coefficient (ICC). Read More

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Quality indicators for dementia and older people nearing the end of life: A systematic review.

J Am Geriatr Soc 2021 Jul 31. Epub 2021 Jul 31.

Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, Cicely Saunders Institute, King's College London, London, UK.

Background: Robust quality indicators (QIs) are essential for monitoring and improving the quality of care and learning from good practice. We aimed to identify and assess QIs for the care of older people and people with dementia who are nearing the end of life and recommend QIs for use with routinely collected electronic data across care settings.

Methods: A systematic review was conducted, including five databases and reference chaining. Read More

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Wound Image Quality From a Mobile Health Tool for Home-Based Chronic Wound Management With Real-Time Quality Feedback: Randomized Feasibility Study.

JMIR Mhealth Uhealth 2021 Jul 30;9(7):e26149. Epub 2021 Jul 30.

Mobile Health Systems Lab, Institute of Robotics and Intelligent Systems, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.

Background: Travel to clinics for chronic wound management is burdensome to patients. Remote assessment and management of wounds using mobile and telehealth approaches can reduce this burden and improve patient outcomes. An essential step in wound documentation is the capture of wound images, but poor image quality can have a negative influence on the reliability of the assessment. Read More

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Seizure Diaries and Forecasting With Wearables: Epilepsy Monitoring Outside the Clinic.

Front Neurol 2021 13;12:690404. Epub 2021 Jul 13.

Department of Medicine, Graeme Clark Institute and St Vincent's Hospital, The University of Melbourne, Fitzroy, VIC, Australia.

It is a major challenge in clinical epilepsy to diagnose and treat a disease characterized by infrequent seizures based on patient or caregiver reports and limited duration clinical testing. The poor reliability of self-reported seizure diaries for many people with epilepsy is well-established, but these records remain necessary in clinical care and therapeutic studies. A number of wearable devices have emerged, which may be capable of detecting seizures, recording seizure data, and alerting caregivers. Read More

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Assessment of the feasibility of frozen sections for the detection of spread through air spaces (STAS) in pulmonary adenocarcinoma.

Mod Pathol 2021 Jul 29. Epub 2021 Jul 29.

Department of Pathology, New York University Langone Health, New York, NY, USA.

Spread through air spaces (STAS) is reportedly associated with worse prognosis in sublobar resections of lung adenocarcinoma. Recently, it was proposed that STAS detected on frozen sections can be an indication for lobectomy instead of sublobar resection. We undertook this study to evaluate the reliability of STAS assessment on frozen sections compared to permanent sections, as well as the associations among STAS, tumor grade, and recurrence-free survival (RFS) after sublobar resection. Read More

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Feasibility and reliability of sentinel lymph node biopsy after neoadjuvant chemotherapy in breast cancer patients with positive axillary nodes at initial diagnosis: An up-to date meta-analysis of 3,578 patients.

Breast 2021 Jul 22;59:256-269. Epub 2021 Jul 22.

Department of Breast and Thyroid Surgery, Peking University Shenzhen Hospital, Shenzhen, Guangdong Province, People's Republic of China. Electronic address:

Purpose: Neoadjuvant chemotherapy (NACT) is increasingly adopted in the therapy of breast cancer (BC) patients with positive axillary nodes (cN+), but the reliability and feasibility of sentinel lymph node biopsy (SLNB) following NACT are still controversial. The objective of the present study is to conduct an updated meta-analysis on this issue.

Methods: A literature search was performed using PubMed, Cochrane, Embase, and Web of Science to identify papers published from January 1, 2000 to October 22, 2020 to research SLNB after NACT in BC patients. Read More

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Assessment of Autism Spectrum Disorder in Deaf Adults with Intellectual Disability: Feasibility and Psychometric Properties of an Adapted Version of the Autism Diagnostic Observation Schedule (ADOS-2).

J Autism Dev Disord 2021 Jul 28. Epub 2021 Jul 28.

Forschungsinstitut für Entwicklungsmedizin, Johannes Kepler Universität Linz, Linz, Austria.

This study describes the adaptation of the autism diagnostic observation schedule (ADOS-2) to assess autism spectrum disorder (ASD) in adults with intellectual disability (ID) and hearing loss who communicate primarily visually. This adapted ADOS-2 was applied to residents of specialized therapeutic living communities (n = 56). The internal consistency of the adapted ADOS-2 was excellent for the Social Affect of modules 2 and 3 and acceptable for Restricted and Repetitive Behaviors subscale of module 2, but poor for module 3. Read More

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Feasibility and reliability of the Self Administered Children's Lifestyle Assessment (SACLA), a new tool to measure children's lifestyle behaviors: the VIF Program.

J Prev Med Hyg 2021 Mar 29;62(1):E117-E121. Epub 2021 Apr 29.

Professeur émérite, University of Lille, CHU Lille, ULR 2694, METRICS: Evaluation des technologies de santé et des pratiques médicales, Lille, France.

Objectives: To develop a self-administered children health-related behaviors assessment, and to test its feasibility and reliability in a group of French children.

Methods: A sample of 216 children participated in the first stage of this study, dedicated to the feasibility assessment. An independent sample of 99 children participated in the assessment of reliability via questionnaire test and retest. Read More

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A novel DNA biosensor for the ultrasensitive detection of DNA methyltransferase activity based on a high-density "hot spot" SERS substrate and rolling circle amplification strategy.

Analyst 2021 Jul 28. Epub 2021 Jul 28.

Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, 225001, P. R. China. and Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Yangzhou University, Yangzhou, P. R. China and Jiangsu Key Laboratory of Experimental & Translational Noncoding RNA Research, Medical College, Yangzhou University, Yangzhou, China.

Herein, we proposed a novel biosensor based on a high-density "hot spot" [email protected] array substrate and rolling circle amplification (RCA) strategy for the ultrasensitive detection of CpG methyltransferase (M.SssI) activity. In the presence of M. Read More

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Validation of the Pediatric Quality of Life Inventory™, Neuromuscular Module, version 3.0 in Spanish for Argentina.

Arch Argent Pediatr 2021 Aug;119(4):e286-e297

Servicio de Kinesiología, Hospital de Pediatría S.A.M.I.C. "Prof. Dr. Juan P. Garrahan", Ciudad Autónoma de Buenos Aires, Argentina.

Objective: To assess the psychometric properties of the Pediatric Quality of Life Inventory™ (PedsQL™ 3.0), Neuromuscular Module, version in Spanish for Argentina, for children aged 2-18 years with neuromuscular disease.

Population And Methods: Observational, analytical, prospective validation study conducted in Hospital Garrahan between March 19th, 2019 and March 9th, 2020. Read More

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Comparing an e-Health program vs home rehabilitation program in patients with non-specific low back pain: A study protocol randomized feasibility trial.

J Back Musculoskelet Rehabil 2021 Jul 13. Epub 2021 Jul 13.

Department of Nursing, Physical Therapy and Medicine, University of Almeria, Spain.

Background: There is little evidence on the reliability of the web application-based rehabilitation systems to treat chronic low back pain (CLBP).

Methods: This protocol describes a double-blind, randomized controlled feasibility trial of an e-Health intervention developed to support the self-management of people with CLBP in primary care physiotherapy. Three Hospitals with primary care for outpatients will be the units of randomisation, in each Hospital the participants will be randomized to one of two groups, a pragmatic control group receiving either the usual home program based on electrostimulation and McKenzie Therapy and e-Health intervention. Read More

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The Feasibility of Using Self-Generated Identification Codes in Longitudinal Research With Military Personnel.

Eval Health Prof 2021 Jul 26:1632787211031625. Epub 2021 Jul 26.

School of Medicine Department of Public Health Sciences, University of Virginia, Charlottesville, VA, USA.

Self-generated identification codes (SGICs) are strings of information based on stable participant characteristics. They are often used in longitudinal research to match data between time points while protecting participant anonymity. However, the use of SGICs with military personnel has been infrequent, even though military personnel do not have the same privacy protections as civilians. Read More

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AMIC for traumatic focal osteochondral defect of the talar shoulder: a 5 years follow-up prospective cohort study.

BMC Musculoskelet Disord 2021 Jul 24;22(1):638. Epub 2021 Jul 24.

Department of Orthopaedics and Trauma Surgery, University Clinic Aachen, RWTH Aachen University Clinic, 52064, Aachen, Germany.

Background: Autologous Matrix-Induced Chondrogenesis (AMIC) is addressed to osteochondral defects of the talus. However, evidence concerning the midterm efficacy and safety of AMIC are limited. This study assessed reliability and feasibility of AMIC at 60 months follow-up. Read More

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The feasibility, reliability, and incremental value of two-dimensional speckle-tracking for the detection of significant coronary stenosis after treadmill stress echocardiography.

Cardiovasc Ultrasound 2021 Jul 23;19(1):27. Epub 2021 Jul 23.

Division of Cardiology, Department of Medicine, Sherbrooke University Hospital Center (CHUS) , 3001, 12e Avenue Nord, Sherbrooke, QC, J1H 5N4, Canada.

Background: Two-dimensional speckle-tracking echocardiography (STE) may help detect coronary artery disease (CAD) when combined with dobutamine stress echocardiography. However, few studies have explored STE with exercise stress echocardiography (ESE). We aimed to evaluate the feasibility, reliability, and incremental value of STE combined with treadmill ESE compared to treadmill ESE alone to detect CAD. Read More

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Estimation and Optimization of Tool Wear in Conventional Turning of 709M40 Alloy Steel Using Support Vector Machine (SVM) with Bayesian Optimization.

Materials (Basel) 2021 Jul 6;14(14). Epub 2021 Jul 6.

Department of Electronics Engineering Technology, College of Technological Studies, P.A.A.E.T., P.O. Box 42325, Shuwaikh 70654, Kuwait.

Cutting tool wear reduces the quality of the product in production processes. The optimization of both the machining parameters and tool life reliability is an increasing research trend to save manufacturing resources. In the present work, we introduced a computational approach in estimating the tool wear in the turning process using artificial intelligence. Read More

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Feasibility and Reliability Assessment of Video-Based Motion Analysis and Surface Electromyography in Children with Fragile X during Gait.

Sensors (Basel) 2021 Jul 12;21(14). Epub 2021 Jul 12.

Department of Women's and Children's Health, University of Padova, 35128 Padova, Italy.

Fragile X Syndrome (FXS), the leading form of inherited intellectual disability and autism, is characterized by specific musculoskeletal conditions. We hypothesized that gait analysis in FXS could be relevant for the evaluation of motor control of gait, and help the understanding of a possible correlation between functional and intellectual abilities. Typical deficits in executive control and hyperactivity have hampered the use of standard gait analysis. Read More

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Assessing avoidance behavior due to concerns about falling: Psychometric properties of the FES-IAB in a sample of older adults of an online panel.

Arch Gerontol Geriatr 2021 Jul 6;97:104469. Epub 2021 Jul 6.

Department of Health Services Research, Care and Public Health Research Institute (CAPHRI), Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, the Netherlands.

Background And Objectives: The Falls Efficacy Scale-International (FES-I) and its shorter version (Short FES-I) are widely used measures of concerns about falling (CaF) and have consistently demonstrated good psychometric properties. The FES-I Avoidance Behavior (FES-IAB) and Short FES-IAB were developed to gain insight into activity avoidance due to CaF and add a question to each item of the FES-I and Short FES-I. The objective was to assess the psychometric properties of the FES-IAB and Short FES-IAB in community-dwelling older people. Read More

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Evaluation of a Wearable AR Platform for Guiding Complex Craniotomies in Neurosurgery.

Ann Biomed Eng 2021 Jul 23. Epub 2021 Jul 23.

Department of Information Engineering, University of Pisa, Pisa, Italy.

Today, neuronavigation is widely used in daily clinical routine to perform safe and efficient surgery. Augmented reality (AR) interfaces can provide anatomical models and preoperative planning contextually blended with the real surgical scenario, overcoming the limitations of traditional neuronavigators. This study aims to demonstrate the reliability of a new-concept AR headset in navigating complex craniotomies. Read More

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Relationship between the ratio of optic nerve sheath diameter to eyeball transverse diameter and morphological characteristics of dogs.

Am J Vet Res 2021 Aug;82(8):667-675

Objective: To assess the feasibility of ocular ultrasonography for measurement of the ratio of optic nerve sheath diameter (ONSD) to eyeball transverse diameter (ETD) in dogs with various morphologies and to evaluate the interobserver reliability of the ONSD/ETD ratio and its correlation with various morphological variables.

Animals: 45 healthy dogs of various breeds.

Procedures: Height, head circumference, body weight, body condition score, intraocular pressure, and blood pressure were recorded for each dog. Read More

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Feasibility and reliability of evaluate PD-L1 expression determination using small biopsy specimens in non-small cell lung cancer.

Thorac Cancer 2021 Jul 21. Epub 2021 Jul 21.

Department of Respiratory and Critical Care Medicine, Peking Union Medical College Hospital, Beijing, China.

Background: Programmed cell death ligand-1 (PD-L1) is a useful biomarker in non-small cell lung cancer (NSCLC) patients who would probably benefit from immunotherapy. In most patients with advanced stage NSCLC, only small biopsy specimens were available for the evaluation of PD-L1 expression. In this study, we evaluated the feasibility and reliability of PD-L1 testing on small biopsy samples. Read More

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Development and validation of the Health-Friendly Activity Index: an assessment tool to comprehensively measure health-friendly activities of corporations or organisations.

BMJ Open 2021 07 19;11(7):e048768. Epub 2021 Jul 19.

Family Science and Social Work, Miami University, Oxford, Ohio, USA.

Objectives: We developed the Health-Friendly Activity Index (HFAI) to comprehensively measure the health-friendly activities of corporations or organisations. We validated the developed tool and reported on its use as an assessment tool to improve consumers' health-related outcomes.

Design: This was a cross-sectional study. Read More

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Cross-validation of the Tunisian version of the National Eye Institute Visual Function Questionnaire 25.

J Fr Ophtalmol 2021 Jul 16. Epub 2021 Jul 16.

Department of Ophthalmology, Fattouma Bourguiba University Hospital, Faculty of Medicine, University of Monastir, 5000 Monastir, Tunisia.

Introduction: The goal of our study was to create a cross-cultural adaptation of the questionnaire « National Eye Institute Visual Function Questionnaire » (NEI-VFQ-25) for the Tunisian population (Tu-VFQ-25) and to test its psychometric properties in a group of patients with chronic uveitis.

Patients And Methods: The study consisted of two steps. The first was translation of the NEI-VFQ-25 and its cross-cultural adaptation to the Tunisian dialect (Tu-VFQ-25) according to the guidelines of Beaton et al. Read More

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A novel strategy based on targeted cellular metabolomics for quantitatively evaluating anti-aging effect and screening effective extracts of Erzhi Wan.

J Chromatogr B Analyt Technol Biomed Life Sci 2021 Jul 10;1178:122857. Epub 2021 Jul 10.

School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China; Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, and National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China.

The complexity of ingredients in traditional Chinese medicine (TCM) makes it challenging to clarify its efficacy in an acceptable and scientific approach. The present study was aimed to use quantification results from targeted cellular metabolomics to evaluate anti-aging efficacy of a famous Chinese medicine formula, Erzhi Wan (EZW), and screen possible effective extracts, depending on the developed strategy integrating multivariate receiver operating characteristic (ROC) curve and analytic hierarchy process (AHP). In this study, senescent NRK cells induced by D-galactose were treated with drug-containing serum of EZW and four kinds of extracts (petroleum ether, ethyl acetate, butanol and water). Read More

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Italian adaptation of the Beaumont Behavioral Inventory (BBI): psychometric properties and clinical usability.

Amyotroph Lateral Scler Frontotemporal Degener 2021 Jul 19:1-6. Epub 2021 Jul 19.

"Rita Levi Montalcini" Department of Neuroscience, University of Turin, ALS Centre, Turin, Italy.

Up to 50% of patients affected by amyotrophic lateral sclerosis (ALS) show behavioral changes within the of frontotemporal degeneration (FTD). Behavioral dysfunctions in ALS patients negatively impact on management, prognosis and survival. It is, thus, crucial to develop ALS-specific psychometric tools for early detecting alterations in behavior. Read More

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Can Visual Acuity Be Reliably Measured at Home? Validation of Telemedicine Remote Computerised Visual Acuity Measurements.

Br Ir Orthopt J 2021 16;17(1):119-126. Epub 2021 Jun 16.

Guy's and St Thomas' NHSFT, GB.

Purpose: The recent pandemic has identified the need for telemedicine assessment of ophthalmology patients. A vital component of such assessment is visual acuity (VA) measurement. The aim of this study was to determine the feasibility and reliability of computerised 'at home' VA measurements using COMPlog software. Read More

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Aero-engine health degradation estimation based on an underdetermined extended Kalman filter and convergence proof.

ISA Trans 2021 Jul 10. Epub 2021 Jul 10.

School of Transportation Science and Engineering, Beihang University, Beijing, 100191, PR China. Electronic address:

In order to improve the reliability of aero-engine, reduce maintenance cost, and promote aircraft safety, lots of attention is paid to health monitoring of aero-engine. The aero-engine gas components involve flow and efficiency parameters, which are key health parameters to obtain the aero-engine' performance degradation. A challenge has to be faced is that these health parameters needed to know are more than the available sensors, which cannot be estimated by the ordinary estimator like Kalman Filter (KF) and Extended Kalman Filter (EKF). Read More

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The Clinical Sustainability Assessment Tool: measuring organizational capacity to promote sustainability in healthcare.

Implement Sci Commun 2021 Jul 17;2(1):77. Epub 2021 Jul 17.

Washington University in St. Louis, Brown School, St. Louis, MO, USA.

Background: Few validated assessment tools are available to increase understanding and measure factors associated with sustainment of clinical practices, an increasingly recognized need among clinicians. We describe the development of the Clinical Sustainability Assessment Tool (CSAT), designed to assess factors that contribute to sustainable practices in clinical settings.

Methods: Sixty-four participants from clinical and research fields participated in concept mapping and were recruited to brainstorm factors that lead to sustained clinical practices. Read More

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